Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells

Journal of Biological Chemistry

Volumn 285, Issue 29, 2010, Pages 22426-22436

  Humphrey, Rohan K ^a   Newcomb, Christina J ^a   Yu, Shu Mei A ^a   Hao, Ergeng ^a   Yu, Doris ^a   Krajewski, Stan ^b   Du, Keyong ^c   Jhala, Ulupi S ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b BURNHAM INSTITUTE   (United States)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BAX TRANSLOCATION; BETA CELL; COCULTURE; CONFORMATIONAL CHANGE; CYTOKINE SIGNALING; CYTOKINES; EX-VIVO; IN-CELL; MAMMALIAN HOMOLOGS; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL TRANSLOCATION; NON-OBESE DIABETICS; PANCREATIC BETA CELLS; PSEUDOKINASE;

CELL DEATH; CELL MEMBRANES; MAMMALS;

CELL CULTURE;

CYTOKINE; MIXED LINEAGE KINASE 3; PHOSPHOTRANSFERASE; PROTEIN BAX; PROTEIN KINASE B; PROTEIN TRB3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME STABILITY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY;

ADULT; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE, TUMOR; COCULTURE TECHNIQUES; CYTOKINES; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INSULIN-SECRETING CELLS; MAP KINASE KINASE KINASES; MICE; MITOCHONDRIA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS;

MAMMALIA; MUS;

EID: 77954565804     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.123786     Document Type: Article

References (57)

1. Widmann, C., Gibson, S., Jarpe, M. B., and Johnson, G. L. (1999) Physiol. Rev. 79, 143-180
2. Sathyanarayana, P., Barthwal, M. K., Kundu, C. N., Lane, M. E., Bergmann, A., Tzivion, G., and Rana, A. (2002) Mol. Cell 10, 1527-1533
3. Korchnak, A. C., Zhan, Y., Aguilar, M. T., and Chadee, D. N. (2009) Cell. Signal. 21, 1620-1625
4. Whitmarsh, A. J., Cavanagh, J., Tournier, C., Yasuda, J., and Davis, R. J. (1998) Science 281, 1671-1674
5. Yasuda, J., Whitmarsh, A. J., Cavanagh, J., Sharma, M., and Davis, R. J. (1999) Mol. Cell. Biol. 19, 7245-7254
6. Tournier, C., Dong, C., Turner, T. K., Jones, S. N., Flavell, R. A., and Davis, R. J. (2001) Genes Dev. 15, 1419-1426
7. Brancho, D., Ventura, J. J., Jaeschke, A., Doran, B., Flavell, R. A., and Davis, R. J. (2005) Mol. Cell. Biol. 25, 3670-3681
8. Xu, Z., Maroney, A. C., Dobrzanski, P., Kukekov, N. V., and Greene, L. A. (2001) Mol. Cell. Biol. 21, 4713-4724
9. Pan, J., Zhang, Q. G., and Zhang, G. Y. (2005) Neuroscience 131, 147-159
10. Bodner, A., Maroney, A. C., Finn, J. P., Ghadge, G., Roos, R., and Miller, R. J. (2002) J. Neurochem. 82, 1424-1434
11. Wang, L. H., Besirli, C. G., and Johnson, E. M., Jr. (2004) Annu. Rev. Pharmacol. Toxicol. 44, 451-474
12. Mayumi-Matsuda, K., Kojima, S., Suzuki, H., and Sakata, T. (1999) Biochem. Biophys. Res. Commun. 258, 260-264
13. Du, K., Herzig, S., Kulkarni, R. N., and Montminy, M. (2003) Science 300, 1574-1577
14. Kennedy, S. G., Kandel, E. S., Cross, T. K., and Hay, N. (1999) Mol. Cell. Biol. 19, 5800-5810
15. Yamaguchi, H., and Wang, H. G. (2001) Oncogene 20, 7779-7786
16. Rathmell, J. C., Fox, C. J., Plas, D. R., Hammerman, P. S., Cinalli, R. M., and Thompson, C. B. (2003) Mol. Cell. Biol. 23, 7315-7328
17. Sheridan, C., and Martin, S. J. (2008) Trends Cell Biol. 18, 353-357
18. Chang, L. K., Putcha, G. V., Deshmukh, M., and Johnson, E. M., Jr. (2002) Biochimie 84, 223-231
19. Sharma, S., Jhala, U. S., Johnson, T., Ferreri, K., Leonard, J., and Montminy, M. (1997) Mol. Cell. Biol. 17, 2598-2604
20. Krajewska, M., Rosenthal, R. E., Mikolajczyk, J., Stennicke, H. R., Wiesenthal, T., Mai, J., Naito, M., Salvesen, G. S., Reed, J. C., Fiskum, G., and Krajewski, S. (2004) Exp. Neurol. 189, 261-279
21. Krajewski, S., Zapata, J. M., Krajewska, M., VanArsdale, T., Shabaik, A., Gascoyne, R. D., and Reed, J. C. (1997) J. Immunol. 159, 5841-5852
22. Krajewski, S., Thor, A. D., Edgerton, S. M., Moore, D. H., 2nd, Krajewska, M., and Reed, J. C. (1997) Clin. Cancer Res. 3, 199-208
23. Kato, S., and Du, K. (2007) Biochem. Biophys. Res. Commun. 353, 933-938
24. Roy, S. K., Shuman, J. D., Platanias, L. C., Shapiro, P. S., Reddy, S. P., Johnson, P. F., and Kalvakolanu, D. V. (2005) J. Biol. Chem. 280, 24462-24471
25. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W., and Vogelstein, B. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 2509-2514
26. Bresson, D., Togher, L., Rodrigo, E., Chen, Y., Bluestone, J. A., Herold, K. C., and von Herrath, M. (2006) J. Clin. Invest. 116, 1371-1381
27. Krajewska, M., Zapata, J. M., Meinhold-Heerlein, I., Hedayat, H., Monks, A., Bettendorf, H., Shabaik, A., Bubendorf, L., Kallioniemi, O. P., Kim, H., Reifenberger, G., Reed, J. C., and Krajewski, S. (2002) Neoplasia 4, 129-140
28. Krajewska, M., Mai, J. K., Zapata, J. M., Ashwell, K. W., Schendel, S. L., Reed, J. C., and Krajewski, S. (2002) Cell Death Differ. 9, 145-157
29. Humphrey, R. K., Yu, S. M., Flores, L. E., and Jhala, U. S. (2010) J. Biol. Chem. 285, 3406-3416
30. Danial, N. N., Gramm, C. F., Scorrano, L., Zhang, C. Y., Krauss, S., Ranger, A. M., Datta, S. R., Greenberg, M. E., Licklider, L. J., Lowell, B. B., Gygi, S. P., and Korsmeyer, S. J. (2003) Nature 424, 952-956
31. Donath, M. Y., Størling, J., Maedler, K., and Mandrup-Poulsen, T. (2003) J. Mol. Med. 81, 455-470
32. Xu, Z., Kukekov, N. V., and Greene, L. A. (2005) Mol. Cell. Biol. 25, 9949-9959
33. Morrison, D. K., and Davis, R. J. (2003) Annu. Rev. Cell Dev. Biol. 19, 91-118
34. Murakata, C., Kaneko, M., Gessner, G., Angeles, T. S., Ator, M. A., O'Kane, T. M., McKenna, B. A., Thomas, B. A., Mathiasen, J. R., Saporito, M. S., Bozyczko-Coyne, D., and Hudkins, R. L. (2002) Bioorg. Med. Chem. Lett. 12, 147-150
35. Ohoka, N., Yoshii, S., Hattori, T., Onozaki, K., and Hayashi, H. (2005) EMBO J. 24, 1243-1255
36. Qian, B., Wang, H., Men, X., Zhang, W., Cai, H., Xu, S., Xu, Y., Ye, L., Wollheim, C. B., and Lou, J. (2008) J. Endocrinol. 199, 407-416
37. Dansen, T. B., Whitfield, J., Rostker, F., Brown-Swigart, L., and Evan, G. I. (2006) J. Biol. Chem. 281, 10890-10895
38. Hsu, Y. T., and Youle, R. J. (1998) J. Biol. Chem. 273, 10777-10783
39. Chao, D. T., and Korsmeyer, S. J. (1998) Annu. Rev. Immunol. 16, 395-419
40. Dijkers, P. F., Birkenkamp, K. U., Lam, E. W., Thomas, N. S., Lammers, J. W., Koenderman, L., and Coffer, P. J. (2002) J. Cell Biol. 156, 531-542
41. Plas, D. R., Talapatra, S., Edinger, A. L., Rathmell, J. C., and Thompson, C. B. (2001) J. Biol. Chem. 276, 12041-12048
42. Bouzakri, K., Ribaux, P., and Halban, P. A. (2009) J. Biol. Chem. 284, 27892-27898
43. Venieratos, P. D., Drossopoulou, G. I., Kapodistria, K. D., Tsilibary, E. C., and Kitsiou, P. V. (2010) Cell. Signal. 22, 791-800
44. Collier, J. J., Fueger, P. T., Hohmeier, H. E., and Newgard, C. B. (2006) Diabetes 55, 1398-1406
45. Kim, S., Millet, I., Kim, H. S., Kim, J. Y., Han, M. S., Lee, M. K., Kim, K. W., Sherwin, R. S., Karin, M., and Lee, M. S. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 1913-1918
46. Cho, S. G., and Choi, E. J. (2002) J. Biochem. Mol. Biol. 35, 24-27
47. Dhanasekaran, D. N., and Reddy, E. P. (2008) Oncogene 27, 6245-6251
48. Parcellier, A., Tintignac, L. A., Zhuravleva, E., and Hemmings, B. A. (2008) Cell. Signal. 20, 21-30
49. Miyamoto, S., Murphy, A. N., and Brown, J. H. (2009) J. Bioenerg. Biomembr. 41, 169-180
50. Cnop, M., Welsh, N., Jonas, J. C., Jörns, A., Lenzen, S., and Eizirik, D. L. (2005) Diabetes 54, Suppl. 2, S97-S107
51. Pacher, P., Beckman, J. S., and Liaudet, L. (2007) Physiol. Rev. 87, 315-424
52. Szabadkai, G., and Duchen, M. R. (2009) Apoptosis 14, 1405-1423
53. Kroemer, G., Galluzzi, L., and Brenner, C. (2007) Physiol. Rev. 87, 99-163
54. Lemasters, J. J., Qian, T., He, L., Kim, J. S., Elmore, S. P., Cascio, W. E., and Brenner, D. A. (2002) Antioxid. Redox Signal. 4, 769-781
55. Chadee, D. N., and Kyriakis, J. M. (2004) Cell Cycle 3, 1227-1229
56. Chadee, D. N., and Kyriakis, J. M. (2004) Nat. Cell Biol. 6, 770-776
57. Stronach, B., and Perrimon, N. (2002) Genes Dev. 16, 377-387