-
1
-
-
84872304968
-
Current and novel drug therapies for idiopathic pulmonary fibrosis
-
doi: 10.2147/DDDT.S29928
-
Adamali, H. I., and Maher, T. M. (2012). Current and novel drug therapies for idiopathic pulmonary fibrosis. Drug Des. Dev. Ther. 6, 261-272. doi: 10.2147/DDDT.S29928.
-
(2012)
Drug Des. Dev. Ther.
, vol.6
, pp. 261-272
-
-
Adamali, H.I.1
Maher, T.M.2
-
2
-
-
33744919279
-
Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis
-
doi: 10.1513/pats.200601-010TK
-
Agostini, C., and Gurrieri, C. (2006). Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis. Proc. Am. Thorac. Soc. 3, 357-363. doi: 10.1513/pats.200601-010TK.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 357-363
-
-
Agostini, C.1
Gurrieri, C.2
-
3
-
-
48949117344
-
Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
-
doi: 10.1016/j.biocel.2008.02.012
-
Andersson-Sjoland, A., de Alba, C. G., Nihlberg, K., Becerril, C., Ramirez, R., Pardo, A., et al. (2008). Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis. Int. J. Biochem. Cell Biol. 40, 2129-2140. doi: 10.1016/j.biocel.2008.02.012.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 2129-2140
-
-
Andersson-Sjoland, A.1
de Alba, C.G.2
Nihlberg, K.3
Becerril, C.4
Ramirez, R.5
Pardo, A.6
-
4
-
-
0037439630
-
Making sense of latent TGFbeta activation
-
doi: 10.1242/jcs.00229
-
Annes, J. P., Munger, J. S., and Rifkin, D. B. (2003). Making sense of latent TGFbeta activation. J Cell Sci. 116(Pt 2), 217-224. doi: 10.1242/jcs.00229.
-
(2003)
J Cell Sci.
, vol.116
, Issue.PART 2
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
5
-
-
77956338352
-
Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF)
-
doi: 10.1016/j.rmed.2010.04.015
-
Antoniou, K. M., Papadaki, H. A., Soufla, G., Kastrinaki, M. C., Damianaki, A., Koutala, H., et al. (2010). Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF). Respir. Med. 104, 1535-1542. doi: 10.1016/j.rmed.2010.04.015.
-
(2010)
Respir. Med.
, vol.104
, pp. 1535-1542
-
-
Antoniou, K.M.1
Papadaki, H.A.2
Soufla, G.3
Kastrinaki, M.C.4
Damianaki, A.5
Koutala, H.6
-
6
-
-
56949093822
-
Different angiogenic CXC chemokine levels in bronchoalveolar lavage fluid after interferon gamma-1b therapy in idiopathic pulmonary fibrosis patients
-
doi: 10.1016/j.pupt.2008.06.005
-
Antoniou, K. M., Tzanakis, N., Tzortzaki, E. G., Malagari, K., Koutsopoulos, A. V., Alexandrakis, M., et al. (2008). Different angiogenic CXC chemokine levels in bronchoalveolar lavage fluid after interferon gamma-1b therapy in idiopathic pulmonary fibrosis patients. Pulm. Pharmacol. Ther. 21, 840-844. doi: 10.1016/j.pupt.2008.06.005.
-
(2008)
Pulm. Pharmacol. Ther.
, vol.21
, pp. 840-844
-
-
Antoniou, K.M.1
Tzanakis, N.2
Tzortzaki, E.G.3
Malagari, K.4
Koutsopoulos, A.V.5
Alexandrakis, M.6
-
7
-
-
28244449083
-
Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts
-
Asano, Y., Ihn, H., Yamane, K., Jinnin, M., Mimura, Y., and Tamaki, K. (2005). Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts. J. Immunol. 175, 7708-7718.
-
(2005)
J. Immunol.
, vol.175
, pp. 7708-7718
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Mimura, Y.5
Tamaki, K.6
-
8
-
-
84888807831
-
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model
-
doi: 10.1189/jlb.0313140
-
Besnard, A. G., Struyf, S., Guabiraba, R., Fauconnier, L., Rouxel, N., Proost, P., et al. (2013). CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model. J. Leukoc. Biol. 94, 1317-1323. doi: 10.1189/jlb.0313140.
-
(2013)
J. Leukoc. Biol.
, vol.94
, pp. 1317-1323
-
-
Besnard, A.G.1
Struyf, S.2
Guabiraba, R.3
Fauconnier, L.4
Rouxel, N.5
Proost, P.6
-
9
-
-
20244383986
-
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor
-
doi: 10.1164/rccm.200405-612OC
-
Bonniaud, P., Margetts, P. J., Kolb, M., Schroeder, J. A., Kapoun, A. M., Damm, D., et al. (2005). Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am. J. Respir. Crit. Care Med. 171, 889-898. doi: 10.1164/rccm.200405-612OC.
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, pp. 889-898
-
-
Bonniaud, P.1
Margetts, P.J.2
Kolb, M.3
Schroeder, J.A.4
Kapoun, A.M.5
Damm, D.6
-
10
-
-
40949099967
-
Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts
-
doi: 10.1111/j.1365-2222.2008.02944.x
-
Borowski, A., Kuepper, M., Horn, U., Knupfer, U., Zissel, G., Hohne, K., et al. (2008). Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts. Clin. Exp. Allergy 38, 619-628. doi: 10.1111/j.1365-2222.2008.02944.x.
-
(2008)
Clin. Exp. Allergy
, vol.38
, pp. 619-628
-
-
Borowski, A.1
Kuepper, M.2
Horn, U.3
Knupfer, U.4
Zissel, G.5
Hohne, K.6
-
11
-
-
50849104286
-
Resident cellular components of the lung: developmental aspects
-
doi: 10.1513/pats.200803-026HR
-
Cardoso, W. V., and Whitsett, J. A. (2008). Resident cellular components of the lung: developmental aspects. Proc. Am. Thorac. Soc. 5, 767-771. doi: 10.1513/pats.200803-026HR.
-
(2008)
Proc. Am. Thorac. Soc.
, vol.5
, pp. 767-771
-
-
Cardoso, W.V.1
Whitsett, J.A.2
-
12
-
-
40349098060
-
Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?
-
doi: 10.1038/sj.bjp.0707603
-
Chambers, R. C. (2008). Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br. J. Pharmacol. 153(Suppl. 1), S367-S378. doi: 10.1038/sj.bjp.0707603.
-
(2008)
Br. J. Pharmacol.
, vol.153
, Issue.SUPPL. 1
-
-
Chambers, R.C.1
-
13
-
-
0025234884
-
Possible mechanisms of bleomycin-induced fibrosis
-
Chandler, D. B. (1990). Possible mechanisms of bleomycin-induced fibrosis. Clin. Chest Med. 11, 21-30.
-
(1990)
Clin. Chest Med.
, vol.11
, pp. 21-30
-
-
Chandler, D.B.1
-
14
-
-
79951805332
-
Epithelial-mesenchymal interactions in pulmonary fibrosis
-
doi: 10.1146/annurev-physiol-012110-142225
-
Chapman, H. A. (2011). Epithelial-mesenchymal interactions in pulmonary fibrosis. Annu. Rev. Physiol. 73, 413-435. doi: 10.1146/annurev-physiol-012110-142225.
-
(2011)
Annu. Rev. Physiol.
, vol.73
, pp. 413-435
-
-
Chapman, H.A.1
-
15
-
-
5444253271
-
Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways
-
doi: 10.1016/j.bbrc.2004.09.157
-
Chen, R., Lim, J. H., Jono, H., Gu, X. X., Kim, Y. S., Basbaum, C. B., et al. (2004). Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways. Biochem. Biophys. Res. Commun. 324, 1087-1094. doi: 10.1016/j.bbrc.2004.09.157.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 1087-1094
-
-
Chen, R.1
Lim, J.H.2
Jono, H.3
Gu, X.X.4
Kim, Y.S.5
Basbaum, C.B.6
-
16
-
-
84882925367
-
Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
-
doi: 10.1016/j.trsl.2013.06.004
-
Chilosi, M., Carloni, A., Rossi, A., and Poletti, V. (2013). Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema. Transl. Res. 162, 156-173. doi: 10.1016/j.trsl.2013.06.004.
-
(2013)
Transl. Res.
, vol.162
, pp. 156-173
-
-
Chilosi, M.1
Carloni, A.2
Rossi, A.3
Poletti, V.4
-
17
-
-
84855614159
-
The pathogenesis of COPD and IPF: distinct horns of the same devil?
-
doi: 10.1186/1465-9921-13-3
-
Chilosi, M., Poletti, V., and Rossi, A. (2012). The pathogenesis of COPD and IPF: distinct horns of the same devil? Respir. Res. 13, 3. doi: 10.1186/1465-9921-13-3.
-
(2012)
Respir. Res.
, vol.13
, pp. 3
-
-
Chilosi, M.1
Poletti, V.2
Rossi, A.3
-
18
-
-
0034960535
-
Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung
-
doi: 10.1136/thorax.56.7.549
-
Coker, R. K., Laurent, G. J., Jeffery, P. K., du Bois, R. M., Black, C. M., and McAnulty, R. J. (2001). Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung. Thorax 56, 549-556. doi: 10.1136/thorax.56.7.549.
-
(2001)
Thorax
, vol.56
, pp. 549-556
-
-
Coker, R.K.1
Laurent, G.J.2
Jeffery, P.K.3
du Bois, R.M.4
Black, C.M.5
McAnulty, R.J.6
-
19
-
-
77958060949
-
Angiogenic and angiostatic chemokines in idiopathic pulmonary fibrosis and granulomatous lung disease
-
doi: 10.1159/000245332
-
Cui, A., Anhenn, O., Theegarten, D., Ohshimo, S., Bonella, F., Sixt, S. U., et al. (2001). Angiogenic and angiostatic chemokines in idiopathic pulmonary fibrosis and granulomatous lung disease. Respiration 80, 372-378. doi: 10.1159/000245332.
-
(2001)
Respiration
, vol.80
, pp. 372-378
-
-
Cui, A.1
Anhenn, O.2
Theegarten, D.3
Ohshimo, S.4
Bonella, F.5
Sixt, S.U.6
-
20
-
-
15244339164
-
Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis
-
Daniels, C. E., Wilkes, M. C., Edens, M., Kottom, T. J., Murphy, S. J., Limper, A. H., et al. (2004). Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J. Clin. Invest. 114, 1308-1316.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
-
21
-
-
84882927097
-
Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability
-
doi: 10.1165/rcmb.2012-0252OC
-
Davidovich, N., DiPaolo, B. C., Lawrence, G. G., Chhour, P., Yehya, N., and Margulies, S. S. (2013). Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability. Am. J. Respir. Cell Mol. Biol. 49, 156-164. doi: 10.1165/rcmb.2012-0252OC.
-
(2013)
Am. J. Respir. Cell Mol. Biol.
, vol.49
, pp. 156-164
-
-
Davidovich, N.1
DiPaolo, B.C.2
Lawrence, G.G.3
Chhour, P.4
Yehya, N.5
Margulies, S.S.6
-
22
-
-
13744255589
-
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
-
Duffield, J. S., Forbes, S. J., Constandinou, C. M., Clay, S., Partolina, M., Vuthoori, S., et al. (2005). Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J. Clin. Invest. 115, 56-65.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 56-65
-
-
Duffield, J.S.1
Forbes, S.J.2
Constandinou, C.M.3
Clay, S.4
Partolina, M.5
Vuthoori, S.6
-
23
-
-
84864332317
-
Idiopathic pulmonary fibrosis is associated with circulating antiepithelial antibodies
-
doi: 10.1007/s00408-012-9390-z
-
Fahim, A., Chong, M. C., Crooks, M. G., and Hart, S. P. (2012). Idiopathic pulmonary fibrosis is associated with circulating antiepithelial antibodies. Lung 190, 451-458. doi: 10.1007/s00408-012-9390-z.
-
(2012)
Lung
, vol.190
, pp. 451-458
-
-
Fahim, A.1
Chong, M.C.2
Crooks, M.G.3
Hart, S.P.4
-
24
-
-
78649735324
-
Airway mucus function and dysfunction
-
doi: 10.1056/NEJMra0910061
-
Fahy, J. V., and Dickey, B. F. (2010). Airway mucus function and dysfunction. N. Engl. J. Med. 363, 2233-2247. doi: 10.1056/NEJMra0910061.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
25
-
-
84878686854
-
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
-
doi: 10.1038/ng.2609
-
Fingerlin, T. E., Murphy, E., Zhang, W., Peljto, A. L., Brown, K. K., Steele, M. P., et al. (2013). Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat. Genet. 45, 613-620. doi: 10.1038/ng.2609.
-
(2013)
Nat. Genet.
, vol.45
, pp. 613-620
-
-
Fingerlin, T.E.1
Murphy, E.2
Zhang, W.3
Peljto, A.L.4
Brown, K.K.5
Steele, M.P.6
-
26
-
-
0035260881
-
Chemokines and disease
-
doi: 10.1038/84209
-
Gerard, C., and Rollins, B. J. (2001). Chemokines and disease. Nat. Immunol. 2, 108-115. doi: 10.1038/84209.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 108-115
-
-
Gerard, C.1
Rollins, B.J.2
-
27
-
-
84881005368
-
Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a
-
doi: 10.1152/ajplung.00014.2013
-
Ghosh, M. C., Gorantla, V., Makena, P. S., Luellen, C., Sinclair, S. E., Schwingshackl, A., et al. (2013). Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a. Am. J. Physiol. Lung Cell. Mol. Physiol. 305, L222-L228. doi: 10.1152/ajplung.00014.2013.
-
(2013)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.305
-
-
Ghosh, M.C.1
Gorantla, V.2
Makena, P.S.3
Luellen, C.4
Sinclair, S.E.5
Schwingshackl, A.6
-
28
-
-
84857651851
-
Epithelial cells utilize cortical actin/myosin to activate latent TGF-beta through integrin alpha(v)beta(6)-dependent physical force
-
doi: 10.1016/j.yexcr.2012.01.020
-
Giacomini, M. M., Travis, M. A., Kudo, M., and Sheppard, D. (2012). Epithelial cells utilize cortical actin/myosin to activate latent TGF-beta through integrin alpha(v)beta(6)-dependent physical force. Exp. Cell Res. 318, 716-722. doi: 10.1016/j.yexcr.2012.01.020.
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 716-722
-
-
Giacomini, M.M.1
Travis, M.A.2
Kudo, M.3
Sheppard, D.4
-
29
-
-
84885470108
-
Bronchial epithelium as a target for innovative treatments in asthma
-
doi: 10.1016/j.pharmthera.2013.07.008
-
Gras, D., Chanez, P., Vachier, I., Petit, A., and Bourdin, A. (2013). Bronchial epithelium as a target for innovative treatments in asthma. Pharmacol. Ther. 140, 290-305. doi: 10.1016/j.pharmthera.2013.07.008.
-
(2013)
Pharmacol. Ther.
, vol.140
, pp. 290-305
-
-
Gras, D.1
Chanez, P.2
Vachier, I.3
Petit, A.4
Bourdin, A.5
-
30
-
-
69949124749
-
Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition
-
doi: 10.1016/j.humpath.2009.02.020
-
Guarino, M., Tosoni, A., and Nebuloni, M. (2009). Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition. Hum. Pathol. 40, 1365-1376. doi: 10.1016/j.humpath.2009.02.020.
-
(2009)
Hum. Pathol.
, vol.40
, pp. 1365-1376
-
-
Guarino, M.1
Tosoni, A.2
Nebuloni, M.3
-
31
-
-
33750182181
-
Mucin overproduction in chronic inflammatory lung disease
-
Hauber, H. P., Foley, S. C., and Hamid, Q. (2006). Mucin overproduction in chronic inflammatory lung disease. Can. Respir. J. 13, 327-335.
-
(2006)
Can. Respir. J.
, vol.13
, pp. 327-335
-
-
Hauber, H.P.1
Foley, S.C.2
Hamid, Q.3
-
32
-
-
1542319868
-
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium
-
doi: 10.1016/S0002-9440(10)63147-1
-
Hong, K. U., Reynolds, S. D., Watkins, S., Fuchs, E., and Stripp, B. R. (2004). Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am. J. Pathol. 164, 577-588. doi: 10.1016/S0002-9440(10)63147-1.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 577-588
-
-
Hong, K.U.1
Reynolds, S.D.2
Watkins, S.3
Fuchs, E.4
Stripp, B.R.5
-
33
-
-
0025874817
-
Neuroepithelial bodies stimulate proliferation of airway epithelium in fetal hamster lung
-
Hoyt, R. F. Jr., McNelly, N. A., McDowell, E. M., and Sorokin, S. P. (1991). Neuroepithelial bodies stimulate proliferation of airway epithelium in fetal hamster lung. Am. J. Physiol. 260(Pt 1), L234-L240.
-
(1991)
Am. J. Physiol.
, vol.260
, Issue.PART 1
-
-
Hoyt Jr., R.F.1
McNelly, N.A.2
McDowell, E.M.3
Sorokin, S.P.4
-
34
-
-
33645579104
-
Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro
-
doi: 10.1007/s00408-005-2560-5
-
Hu, Y., Peng, J., Feng, D., Chu, L., Li, X., Jin, Z., et al. (2006). Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro. Lung 184, 33-42. doi: 10.1007/s00408-005-2560-5.
-
(2006)
Lung
, vol.184
, pp. 33-42
-
-
Hu, Y.1
Peng, J.2
Feng, D.3
Chu, L.4
Li, X.5
Jin, Z.6
-
35
-
-
84878599042
-
MUC5B promoter polymorphism and interstitial lung abnormalities
-
doi: 10.1056/NEJMoa1216076
-
Hunninghake, G. M., Hatabu, H., Okajima, Y., Gao, W., Dupuis, J., Latourelle, J. C., et al. (2013). MUC5B promoter polymorphism and interstitial lung abnormalities. N. Engl. J. Med. 368, 2192-2200. doi: 10.1056/NEJMoa1216076.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 2192-2200
-
-
Hunninghake, G.M.1
Hatabu, H.2
Okajima, Y.3
Gao, W.4
Dupuis, J.5
Latourelle, J.C.6
-
36
-
-
43049146157
-
The role of proteases in transforming growth factor-beta activation
-
doi: 10.1016/j.biocel.2007.11.026
-
Jenkins, G. (2008). The role of proteases in transforming growth factor-beta activation. Int. J. Biochem. Cell Biol. 40, 1068-1078. doi: 10.1016/j.biocel.2007.11.026.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 1068-1078
-
-
Jenkins, G.1
-
37
-
-
33745183811
-
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury
-
doi: 10.1172/JCI27183
-
Jenkins, R. G., Su, X., Su, G., Scotton, C. J., Camerer, E., Laurent, G. J., et al. (2006). Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J. Clin. Invest. 116, 1606-1614. doi: 10.1172/JCI27183.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1606-1614
-
-
Jenkins, R.G.1
Su, X.2
Su, G.3
Scotton, C.J.4
Camerer, E.5
Laurent, G.J.6
-
38
-
-
30744462300
-
Regulation of lung injury and repair by Toll-like receptors and hyaluronan
-
doi: 10.1038/nm1315
-
Jiang, D., Liang, J., Fan, J., Yu, S., Chen, S., Luo, Y., et al. (2005). Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat. Med. 11, 1173-1179. doi: 10.1038/nm1315.
-
(2005)
Nat. Med.
, vol.11
, pp. 1173-1179
-
-
Jiang, D.1
Liang, J.2
Fan, J.3
Yu, S.4
Chen, S.5
Luo, Y.6
-
39
-
-
84855844345
-
Pathogenesis of idiopathic pulmonary fibrosis: from initial apoptosis of epithelial cells to lung remodeling?
-
Jin, H. L., and Dong, J. C. (2011). Pathogenesis of idiopathic pulmonary fibrosis: from initial apoptosis of epithelial cells to lung remodeling? Chin. Med. J. 124, 4330-4338.
-
(2011)
Chin. Med. J.
, vol.124
, pp. 4330-4338
-
-
Jin, H.L.1
Dong, J.C.2
-
40
-
-
38349060783
-
Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis
-
doi: 10.1378/chest.07-1948
-
Kinder, B. W., Brown, K. K., Schwarz, M. I., Ix, J. H., Kervitsky, A., and King, T. E. Jr. (2008). Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis. Chest 133, 226-232. doi: 10.1378/chest.07-1948.
-
(2008)
Chest
, vol.133
, pp. 226-232
-
-
Kinder, B.W.1
Brown, K.K.2
Schwarz, M.I.3
Ix, J.H.4
Kervitsky, A.5
King Jr., T.E.6
-
41
-
-
82755161052
-
Idiopathic pulmonary fibrosis
-
doi: 10.1016/S0140-6736(11)60052-4
-
King, T. E. Jr., Pardo, A., and Selman, M. (2011). Idiopathic pulmonary fibrosis. Lancet 378, 1949-1961. doi: 10.1016/S0140-6736(11)60052-4.
-
(2011)
Lancet
, vol.378
, pp. 1949-1961
-
-
King Jr., T.E.1
Pardo, A.2
Selman, M.3
-
42
-
-
67449083692
-
Global impairment of CD4+CD25+FOXP3+ regulatory T cells in idiopathic pulmonary fibrosis
-
doi: 10.1164/rccm.200812-1936OC
-
Kotsianidis, I., Nakou, E., Bouchliou, I., Tzouvelekis, A., Spanoudakis, E., Steiropoulos, P., et al. (2009). Global impairment of CD4+CD25+FOXP3+ regulatory T cells in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 179, 1121-1130. doi: 10.1164/rccm.200812-1936OC.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 1121-1130
-
-
Kotsianidis, I.1
Nakou, E.2
Bouchliou, I.3
Tzouvelekis, A.4
Spanoudakis, E.5
Steiropoulos, P.6
-
43
-
-
0032717522
-
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
-
doi: 10.1172/JCI5628
-
Kuwano, K., Hagimoto, N., Kawasaki, M., Yatomi, T., Nakamura, N., Nagata, S., et al. (1999). Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J. Clin. Invest. 104, 13-19. doi: 10.1172/JCI5628.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 13-19
-
-
Kuwano, K.1
Hagimoto, N.2
Kawasaki, M.3
Yatomi, T.4
Nakamura, N.5
Nagata, S.6
-
44
-
-
0035903306
-
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1)
-
doi: 10.1084/jem.194.6.809
-
Lee, C. G., Homer, R. J., Zhu, Z., Lanone, S., Wang, X., Koteliansky, V., et al. (2001). Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J. Exp. Med. 194, 809-821. doi: 10.1084/jem.194.6.809.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 809-821
-
-
Lee, C.G.1
Homer, R.J.2
Zhu, Z.3
Lanone, S.4
Wang, X.5
Koteliansky, V.6
-
45
-
-
84863012828
-
Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis
-
doi: 10.1183/09031936.00050911
-
Lee, J. S., Song, J. W., Wolters, P. J., Elicker, B. M., King, T. E. Jr., Kim, D. S., et al. (2012). Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis. Eur. Respir. J. 39, 352-358. doi: 10.1183/09031936.00050911.
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 352-358
-
-
Lee, J.S.1
Song, J.W.2
Wolters, P.J.3
Elicker, B.M.4
King Jr., T.E.5
Kim, D.S.6
-
46
-
-
0035094928
-
Pulmonary collectins and innate host defense of the lung
-
doi: 10.1016/S1286-4579(00)01363-0
-
LeVine, A. M., and Whitsett, J. A. (2001). Pulmonary collectins and innate host defense of the lung. Microbes Infect. 3, 161-166. doi: 10.1016/S1286-4579(00)01363-0.
-
(2001)
Microbes Infect.
, vol.3
, pp. 161-166
-
-
LeVine, A.M.1
Whitsett, J.A.2
-
47
-
-
0031029855
-
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease
-
doi: 10.1073/pnas.94.3.967
-
Li, J. D., Dohrman, A. F., Gallup, M., Miyata, S., Gum, J. R., Kim, Y. S., et al. (1997). Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc. Natl. Acad. Sci. U.S.A. 94, 967-972. doi: 10.1073/pnas.94.3.967.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 967-972
-
-
Li, J.D.1
Dohrman, A.F.2
Gallup, M.3
Miyata, S.4
Gum, J.R.5
Kim, Y.S.6
-
48
-
-
78650925648
-
Epithelium-specific deletion of TGF-beta receptor type II protects mice from bleomycin-induced pulmonary fibrosis
-
doi: 10.1172/JCI42090
-
Li, M., Krishnaveni, M. S., Li, C., Zhou, B., Xing, Y., Banfalvi, A., et al. (2011). Epithelium-specific deletion of TGF-beta receptor type II protects mice from bleomycin-induced pulmonary fibrosis. J. Clin. Invest. 121, 277-287. doi: 10.1172/JCI42090.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 277-287
-
-
Li, M.1
Krishnaveni, M.S.2
Li, C.3
Zhou, B.4
Xing, Y.5
Banfalvi, A.6
-
49
-
-
78149483354
-
CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice
-
doi: 10.1371/journal.pone.0015404
-
Liu, F., Liu, J., Weng, D., Chen, Y., Song, L., He, Q., et al. (2010). CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice. PLoS ONE 5:e15404. doi: 10.1371/journal.pone.0015404.
-
(2010)
PLoS ONE
, vol.5
-
-
Liu, F.1
Liu, J.2
Weng, D.3
Chen, Y.4
Song, L.5
He, Q.6
-
50
-
-
33646481327
-
Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis
-
Marchal-Somme, J., Uzunhan, Y., Marchand-Adam, S., Valeyre, D., Soumelis, V., Crestani, B., et al. (2006). Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J. Immunol. 176, 5735-5739.
-
(2006)
J. Immunol.
, vol.176
, pp. 5735-5739
-
-
Marchal-Somme, J.1
Uzunhan, Y.2
Marchand-Adam, S.3
Valeyre, D.4
Soumelis, V.5
Crestani, B.6
-
51
-
-
79960429928
-
Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study
-
doi: 10.1186/1755-1536-3-20
-
Margaritopoulos, G. A., Antoniou, K. M., Karagiannis, K., Samara, K. D., Lasithiotaki, I., Vassalou, E., et al. (2010). Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study. Fibrogenesis Tissue Repair 3, 20. doi: 10.1186/1755-1536-3-20.
-
(2010)
Fibrogenesis Tissue Repair
, vol.3
, pp. 20
-
-
Margaritopoulos, G.A.1
Antoniou, K.M.2
Karagiannis, K.3
Samara, K.D.4
Lasithiotaki, I.5
Vassalou, E.6
-
52
-
-
84880128903
-
An update on idiopathic pulmonary fibrosis
-
Margaritopoulos, G. A., Giannarakis, I., Siafakas, N. M., and Antoniou, K. M. (2013). An update on idiopathic pulmonary fibrosis. Panminerva Med. 55, 109-120.
-
(2013)
Panminerva Med.
, vol.55
, pp. 109-120
-
-
Margaritopoulos, G.A.1
Giannarakis, I.2
Siafakas, N.M.3
Antoniou, K.M.4
-
53
-
-
84882580383
-
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
-
doi: 10.1016/j.immuni.2013.07.018
-
McHedlidze, T., Waldner, M., Zopf, S., Walker, J., Rankin, A. L., Schuchmann, M., et al. (2013). Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis. Immunity 39, 357-371. doi: 10.1016/j.immuni.2013.07.018.
-
(2013)
Immunity
, vol.39
, pp. 357-371
-
-
McHedlidze, T.1
Waldner, M.2
Zopf, S.3
Walker, J.4
Rankin, A.L.5
Schuchmann, M.6
-
54
-
-
0029808003
-
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44
-
doi: 10.1172/JCI119054
-
McKee, C. M., Penno, M. B., Cowman, M., Burdick, M. D., Strieter, R. M., Bao, C., et al. (1996). Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. J. Clin. Invest. 98, 2403-2413. doi: 10.1172/JCI119054.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2403-2413
-
-
McKee, C.M.1
Penno, M.B.2
Cowman, M.3
Burdick, M.D.4
Strieter, R.M.5
Bao, C.6
-
55
-
-
63349085645
-
Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis
-
doi: 10.1164/rccm.200712-1827OC
-
Mercer, P. F., Johns, R. H., Scotton, C. J., Krupiczojc, M. A., Konigshoff, M., Howell, D. C., et al. (2009). Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 179, 414-425. doi: 10.1164/rccm.200712-1827OC.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 414-425
-
-
Mercer, P.F.1
Johns, R.H.2
Scotton, C.J.3
Krupiczojc, M.A.4
Konigshoff, M.5
Howell, D.C.6
-
56
-
-
84881397595
-
Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4
-
doi: 10.1126/science.1240342
-
Millien, V. O., Lu, W., Shaw, J., Yuan, X., Mak, G., Roberts, L., et al. (2013). Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4. Science 341, 792-796. doi: 10.1126/science.1240342.
-
(2013)
Science
, vol.341
, pp. 792-796
-
-
Millien, V.O.1
Lu, W.2
Shaw, J.3
Yuan, X.4
Mak, G.5
Roberts, L.6
-
57
-
-
70450187617
-
The regulation of TGFbeta signal transduction
-
doi: 10.1242/dev.030338
-
Moustakas, A., and Heldin, C. H. (2009). The regulation of TGFbeta signal transduction. Development 136, 3699-3714. doi: 10.1242/dev.030338.
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
58
-
-
0033524949
-
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis
-
doi: 10.1016/S0092-8674(00)80545-0
-
Munger, J. S., Huang, X., Kawakatsu, H., Griffiths, M. J., Dalton, S. L., Wu, J., et al. (1999). The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 96, 319-328. doi: 10.1016/S0092-8674(00)80545-0.
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.4
Dalton, S.L.5
Wu, J.6
-
59
-
-
48949117336
-
Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2
-
doi: 10.1016/j.biocel.2008.02.016
-
Murray, L. A., Argentieri, R. L., Farrell, F. X., Bracht, M., Sheng, H., Whitaker, B., et al. (2008). Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2. Int. J. Biochem. Cell Biol. 40, 2174-2182. doi: 10.1016/j.biocel.2008.02.016.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 2174-2182
-
-
Murray, L.A.1
Argentieri, R.L.2
Farrell, F.X.3
Bracht, M.4
Sheng, H.5
Whitaker, B.6
-
60
-
-
33747780497
-
Shotgun proteomic analysis of human-induced sputum
-
doi: 10.1002/pmic.200600011
-
Nicholas, B., Skipp, P., Mould, R., Rennard, S., Davies, D. E., O'Connor, C. D., et al. (2006). Shotgun proteomic analysis of human-induced sputum. Proteomics 6, 4390-4401. doi: 10.1002/pmic.200600011.
-
(2006)
Proteomics
, vol.6
, pp. 4390-4401
-
-
Nicholas, B.1
Skipp, P.2
Mould, R.3
Rennard, S.4
Davies, D.E.5
O'Connor, C.D.6
-
61
-
-
73549107232
-
Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders
-
doi: 10.2353/ajpath.2009.090393
-
Nishimura, S. L. (2009). Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders. Am. J. Pathol. 175, 1362-1370. doi: 10.2353/ajpath.2009.090393.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 1362-1370
-
-
Nishimura, S.L.1
-
62
-
-
84864740280
-
Pulmonary fibrosis: patterns and perpetrators
-
doi: 10.1172/JCI60323
-
Noble, P. W., Barkauskas, C. E., and Jiang, D. (2012). Pulmonary fibrosis: patterns and perpetrators. J. Clin. Invest. 122, 2756-2762. doi: 10.1172/JCI60323.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2756-2762
-
-
Noble, P.W.1
Barkauskas, C.E.2
Jiang, D.3
-
63
-
-
84890478294
-
The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis
-
O'Dwyer, D. N., Armstrong, M. E., Trujillo, G., Cooke, G., Keane, M. P., Fallon, P. G., et al. (2013). The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 188, 1442-1450.
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.188
, pp. 1442-1450
-
-
O'Dwyer, D.N.1
Armstrong, M.E.2
Trujillo, G.3
Cooke, G.4
Keane, M.P.5
Fallon, P.G.6
-
64
-
-
0034027869
-
Increase of lung neutrophils in hypersensitivity pneumonitis is associated with lung fibrosis
-
doi: 10.1164/ajrccm.161.5.9907065
-
Pardo, A., Barrios, R., Gaxiola, M., Segura-Valdez, L., Carrillo, G., Estrada, A., et al. (2000). Increase of lung neutrophils in hypersensitivity pneumonitis is associated with lung fibrosis. Am. J. Respir. Crit. Care Med. 161, 1698-1704. doi: 10.1164/ajrccm.161.5.9907065.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
, pp. 1698-1704
-
-
Pardo, A.1
Barrios, R.2
Gaxiola, M.3
Segura-Valdez, L.4
Carrillo, G.5
Estrada, A.6
-
65
-
-
77953585588
-
Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice
-
doi: 10.1016/j.ijrobp.2009.12.065
-
Paun, A., Fox, J., Balloy, V., Chignard, M., Qureshi, S. T., and Haston, C. K. (2010). Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice. Int. J. Radiat. Oncol. Biol. Phys. 77, 1198-1205. doi: 10.1016/j.ijrobp.2009.12.065.
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.77
, pp. 1198-1205
-
-
Paun, A.1
Fox, J.2
Balloy, V.3
Chignard, M.4
Qureshi, S.T.5
Haston, C.K.6
-
66
-
-
84878600828
-
Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis
-
doi: 10.1001/jama.2013.5827
-
Peljto, A. L., Zhang, Y., Fingerlin, T. E., Ma, S. F., Garcia, J. G., Richards, T. J., et al. (2013). Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis. JAMA 309, 2232-2239. doi: 10.1001/jama.2013.5827.
-
(2013)
JAMA
, vol.309
, pp. 2232-2239
-
-
Peljto, A.L.1
Zhang, Y.2
Fingerlin, T.E.3
Ma, S.F.4
Garcia, J.G.5
Richards, T.J.6
-
67
-
-
36348944476
-
Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: a relation to transforming growth factor-beta1 production and fibroblast proliferation
-
doi: 10.1378/chest.07-1373
-
Perng, D. W., Chang, K. T., Su, K. C., Wu, Y. C., Wu, M. T., Hsu, W. H., et al. (2007). Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: a relation to transforming growth factor-beta1 production and fibroblast proliferation. Chest 132, 1548-1556. doi: 10.1378/chest.07-1373.
-
(2007)
Chest
, vol.132
, pp. 1548-1556
-
-
Perng, D.W.1
Chang, K.T.2
Su, K.C.3
Wu, Y.C.4
Wu, M.T.5
Hsu, W.H.6
-
68
-
-
13844314302
-
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis
-
doi: 10.1378/chest.127.1.266
-
Plataki, M., Koutsopoulos, A. V., Darivianaki, K., Delides, G., Siafakas, N. M., and Bouros, D. (2005). Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest 127, 266-274. doi: 10.1378/chest.127.1.266.
-
(2005)
Chest
, vol.127
, pp. 266-274
-
-
Plataki, M.1
Koutsopoulos, A.V.2
Darivianaki, K.3
Delides, G.4
Siafakas, N.M.5
Bouros, D.6
-
69
-
-
69049106527
-
Non-invasive biomarkers in pulmonary fibrosis
-
doi: 10.1111/j.1440-1843.2009.01600.x
-
Prasse, A., and Muller-Quernheim, J. (2009). Non-invasive biomarkers in pulmonary fibrosis. Respirology 14, 788-795. doi: 10.1111/j.1440-1843.2009.01600.x.
-
(2009)
Respirology
, vol.14
, pp. 788-795
-
-
Prasse, A.1
Muller-Quernheim, J.2
-
70
-
-
33645845729
-
Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis
-
doi: 10.1111/j.1365-2362.2006.01636.x
-
Psathakis, K., Mermigkis, D., Papatheodorou, G., Loukides, S., Panagou, P., Polychronopoulos, V., et al. (2006). Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis. Eur. J. Clin. Invest. 36, 362-367. doi: 10.1111/j.1365-2362.2006.01636.x.
-
(2006)
Eur. J. Clin. Invest.
, vol.36
, pp. 362-367
-
-
Psathakis, K.1
Mermigkis, D.2
Papatheodorou, G.3
Loukides, S.4
Panagou, P.5
Polychronopoulos, V.6
-
71
-
-
84864754040
-
Building and maintaining the epithelium of the lung
-
doi: 10.1172/JCI60519
-
Rackley, C. R., and Stripp, B. R. (2012). Building and maintaining the epithelium of the lung. J. Clin. Invest. 122, 2724-2730. doi: 10.1172/JCI60519.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2724-2730
-
-
Rackley, C.R.1
Stripp, B.R.2
-
72
-
-
30844450369
-
Stimulation of Toll-like receptor 2 with bleomycin results in cellular activation and secretion of pro-inflammatory cytokines and chemokines
-
doi: 10.1016/j.taap.2005.05.002
-
Razonable, R. R., Henault, M., and Paya, C. V. (2006). Stimulation of Toll-like receptor 2 with bleomycin results in cellular activation and secretion of pro-inflammatory cytokines and chemokines. Toxicol. Appl. Pharmacol. 210, 181-189. doi: 10.1016/j.taap.2005.05.002.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.210
, pp. 181-189
-
-
Razonable, R.R.1
Henault, M.2
Paya, C.V.3
-
73
-
-
84855264195
-
Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis
-
doi: 10.1164/rccm.201101-0058OC
-
Richards, T. J., Kaminski, N., Baribaud, F., Flavin, S., Brodmerkel, C., Horowitz, D., et al. (2012). Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 185, 67-76. doi: 10.1164/rccm.201101-0058OC.
-
(2012)
Am. J. Respir. Crit. Care Med.
, vol.185
, pp. 67-76
-
-
Richards, T.J.1
Kaminski, N.2
Baribaud, F.3
Flavin, S.4
Brodmerkel, C.5
Horowitz, D.6
-
74
-
-
0027145535
-
Cell adhesion molecules and the bronchial epithelium
-
doi: 10.1164/ajrccm/148.6_Pt_2.S79
-
Roche, W. R., Montefort, S., Baker, J., and Holgate, S. T. (1993). Cell adhesion molecules and the bronchial epithelium. Am. Rev. Respir. Dis. 148(Pt 2), S79-S82. doi: 10.1164/ajrccm/148.6_Pt_2.S79.
-
(1993)
Am. Rev. Respir. Dis.
, vol.148
, Issue.PART 2
-
-
Roche, W.R.1
Montefort, S.2
Baker, J.3
Holgate, S.T.4
-
75
-
-
2342523999
-
Airway mucus hypersecretion in asthma: an undervalued pathology?
-
doi: 10.1016/j.coph.2004.01.011
-
Rogers, D. F. (2004). Airway mucus hypersecretion in asthma: an undervalued pathology? Curr. Opin. Pharmacol. 4, 241-250. doi: 10.1016/j.coph.2004.01.011.
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 241-250
-
-
Rogers, D.F.1
-
76
-
-
24344448730
-
Bone marrow-derived mesenchymal stem cells in repair of the injured lung
-
doi: 10.1165/rcmb.2004-0330OC
-
Rojas, M., Xu, J., Woods, C. R., Mora, A. L., Spears, W., Roman, J., et al. (2005). Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am. J. Respir. Cell Mol. Biol. 33, 145-152. doi: 10.1165/rcmb.2004-0330OC.
-
(2005)
Am. J. Respir. Cell Mol. Biol.
, vol.33
, pp. 145-152
-
-
Rojas, M.1
Xu, J.2
Woods, C.R.3
Mora, A.L.4
Spears, W.5
Roman, J.6
-
77
-
-
0035190667
-
Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia
-
doi: 10.1165/ajrcmb.25.5.f218
-
Rose, M. C., Nickola, T. J., and Voynow, J. A. (2001). Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. Am. J. Respir. Cell Mol. Biol. 25, 533-537. doi: 10.1165/ajrcmb.25.5.f218.
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.25
, pp. 533-537
-
-
Rose, M.C.1
Nickola, T.J.2
Voynow, J.A.3
-
78
-
-
84877086317
-
Fibrosis of two: epithelial cell-fibroblast interactions in pulmonary fibrosis
-
doi: 10.1016/j.bbadis.2013.03.001
-
Sakai, N., and Tager, A. M. (2013). Fibrosis of two: epithelial cell-fibroblast interactions in pulmonary fibrosis. Biochim. Biophys. Acta 1832, 911-921. doi: 10.1016/j.bbadis.2013.03.001.
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 911-921
-
-
Sakai, N.1
Tager, A.M.2
-
79
-
-
84860290510
-
Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis
-
doi: 10.3892/ijo.2012.1374
-
Samara, K. D., Antoniou, K. M., Karagiannis, K., Margaritopoulos, G., Lasithiotaki, I., Koutala, E., et al. (2012). Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis. Int. J. Oncol. 40, 1397-1404. doi: 10.3892/ijo.2012.1374.
-
(2012)
Int. J. Oncol.
, vol.40
, pp. 1397-1404
-
-
Samara, K.D.1
Antoniou, K.M.2
Karagiannis, K.3
Margaritopoulos, G.4
Lasithiotaki, I.5
Koutala, E.6
-
80
-
-
79961139550
-
TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions
-
doi: 10.1042/CS20110086
-
Santibanez, J. F., Quintanilla, M., and Bernabeu, C. (2011). TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions. Clin. Sci. 121, 233-251. doi: 10.1042/CS20110086.
-
(2011)
Clin. Sci.
, vol.121
, pp. 233-251
-
-
Santibanez, J.F.1
Quintanilla, M.2
Bernabeu, C.3
-
81
-
-
0031799055
-
Mechanical strain inhibits repair of airway epithelium in vitro
-
Savla, U., and Waters, C. M. (1998). Mechanical strain inhibits repair of airway epithelium in vitro. Am. J. Physiol. 274(Pt 1), L883-L892.
-
(1998)
Am. J. Physiol.
, vol.274
, Issue.PART 1
-
-
Savla, U.1
Waters, C.M.2
-
82
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
doi: 10.1038/nature00858
-
Scaffidi, P., Misteli, T., and Bianchi, M. E. (2002). Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418, 191-195. doi: 10.1038/nature00858.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
83
-
-
33745840859
-
Hyaluronan fragments act as an endogenous danger signal by engaging TLR2
-
Scheibner, K. A., Lutz, M. A., Boodoo, S., Fenton, M. J., Powell, J. D., and Horton, M. R. (2006). Hyaluronan fragments act as an endogenous danger signal by engaging TLR2. J. Immunol. 177, 1272-1281.
-
(2006)
J. Immunol.
, vol.177
, pp. 1272-1281
-
-
Scheibner, K.A.1
Lutz, M.A.2
Boodoo, S.3
Fenton, M.J.4
Powell, J.D.5
Horton, M.R.6
-
84
-
-
79955146233
-
A common MUC5B promoter polymorphism and pulmonary fibrosis
-
doi: 10.1056/NEJMoa1013660
-
Seibold, M. A., Wise, A. L., Speer, M. C., Steele, M. P., Brown, K. K., Loyd, J. E., et al. (2011). A common MUC5B promoter polymorphism and pulmonary fibrosis. N. Engl. J. Med. 364, 1503-1512. doi: 10.1056/NEJMoa1013660.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1503-1512
-
-
Seibold, M.A.1
Wise, A.L.2
Speer, M.C.3
Steele, M.P.4
Brown, K.K.5
Loyd, J.E.6
-
85
-
-
33744924735
-
Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers
-
doi: 10.1513/pats.200601-003TK
-
Selman, M., and Pardo, A. (2006). Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. Proc. Am. Thorac. Soc. 3, 364-372. doi: 10.1513/pats.200601-003TK.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 364-372
-
-
Selman, M.1
Pardo, A.2
-
86
-
-
84868230311
-
Alveolar epithelial cell injury as an etiopathogenic factor in pulmonary fibrosis
-
doi: 10.1016/S0300-2896(12)70044-3
-
Serrano-Mollar, A. (2012). Alveolar epithelial cell injury as an etiopathogenic factor in pulmonary fibrosis. Arch. Bronconeumol. 48(Suppl. 2), 2-6. doi: 10.1016/S0300-2896(12)70044-3.
-
(2012)
Arch. Bronconeumol.
, vol.48
, Issue.SUPPL. 2
, pp. 2-6
-
-
Serrano-Mollar, A.1
-
87
-
-
33745808765
-
Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis
-
doi: 10.1513/pats.200601-008AW
-
Sheppard, D. (2006). Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc. Am. Thorac. Soc. 3, 413-417. doi: 10.1513/pats.200601-008AW.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 413-417
-
-
Sheppard, D.1
-
88
-
-
33645659496
-
Proteolytic activation of latent TGF-beta precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells
-
doi: 10.1002/jcp.20607
-
Solovyan, V. T., and Keski-Oja, J. (2006). Proteolytic activation of latent TGF-beta precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells. J. Cell. Physiol. 207, 445-453. doi: 10.1002/jcp.20607.
-
(2006)
J. Cell. Physiol.
, vol.207
, pp. 445-453
-
-
Solovyan, V.T.1
Keski-Oja, J.2
-
89
-
-
70849133707
-
Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation
-
doi: 10.1080/01902140902759282
-
Sterclova, M., Vasakova, M., Pavlicek, J., Metlicka, M., Krasna, E., and Striz, I. (2009). Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation. Exp. Lung Res. 35, 514-523. doi: 10.1080/01902140902759282.
-
(2009)
Exp. Lung Res.
, vol.35
, pp. 514-523
-
-
Sterclova, M.1
Vasakova, M.2
Pavlicek, J.3
Metlicka, M.4
Krasna, E.5
Striz, I.6
-
90
-
-
20244390429
-
The functional role of the ELR motif in CXC chemokine-mediated angiogenesis
-
doi: 10.1074/jbc.270.45.27348
-
Strieter, R. M., Polverini, P. J., Kunkel, S. L., Arenberg, D. A., Burdick, M. D., Kasper, J., et al. (1995). The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J. Biol. Chem. 270, 27348-27357. doi: 10.1074/jbc.270.45.27348.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27348-27357
-
-
Strieter, R.M.1
Polverini, P.J.2
Kunkel, S.L.3
Arenberg, D.A.4
Burdick, M.D.5
Kasper, J.6
-
91
-
-
3142768881
-
Effects of interferon-gamma 1b on biomarker expression in patients with idiopathic pulmonary fibrosis
-
doi: 10.1164/rccm.200312-1670OC
-
Strieter, R. M., Starko, K. M., Enelow, R. I., Noth, I., and Valentine, V. G. (2004). Effects of interferon-gamma 1b on biomarker expression in patients with idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 170, 133-140. doi: 10.1164/rccm.200312-1670OC.
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.170
, pp. 133-140
-
-
Strieter, R.M.1
Starko, K.M.2
Enelow, R.I.3
Noth, I.4
Valentine, V.G.5
-
92
-
-
45849148542
-
The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo
-
doi: 10.1080/15476910802085822
-
Sullivan, D. E., Ferris, M., Pociask, D., and Brody, A. R. (2008). The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo. J. Immunotoxicol. 5, 145-149. doi: 10.1080/15476910802085822.
-
(2008)
J. Immunotoxicol.
, vol.5
, pp. 145-149
-
-
Sullivan, D.E.1
Ferris, M.2
Pociask, D.3
Brody, A.R.4
-
93
-
-
79952719285
-
Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis
-
doi: 10.1164/rccm.201001-0076OC
-
Taille, C., Grootenboer-Mignot, S., Boursier, C., Michel, L., Debray, M. P., Fagart, J., et al. (2011). Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 183, 759-766. doi: 10.1164/rccm.201001-0076OC.
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 759-766
-
-
Taille, C.1
Grootenboer-Mignot, S.2
Boursier, C.3
Michel, L.4
Debray, M.P.5
Fagart, J.6
-
94
-
-
84865820041
-
TGF-beta activation and lung fibrosis
-
doi: 10.1513/pats.201201-003AW
-
Tatler, A. L., and Jenkins, G. (2012). TGF-beta activation and lung fibrosis. Proc. Am. Thorac. Soc. 9, 130-136. doi: 10.1513/pats.201201-003AW.
-
(2012)
Proc. Am. Thorac. Soc.
, vol.9
, pp. 130-136
-
-
Tatler, A.L.1
Jenkins, G.2
-
95
-
-
84861394764
-
Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis
-
doi: 10.1056/NEJMoa1113354
-
The Idiopathic Pulmonary Fibrosis Clinical Research Network. (2012). Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis. N. Engl. J. Med. 366, 1968-1977. doi: 10.1056/NEJMoa1113354.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1968-1977
-
-
The Idiopathic Pulmonary Fibrosis Clinical Research, Network.1
-
96
-
-
0036570052
-
Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred
-
doi: 10.1164/rccm.200112-123OC
-
Thomas, A. Q., Lane, K., Phillips, J. III, Prince, M., Markin, C., Speer, M., et al. (2002). Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. Am. J. Respir. Crit. Care Med. 165, 1322-1328. doi: 10.1164/rccm.200112-123OC.
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.165
, pp. 1322-1328
-
-
Thomas, A.Q.1
Lane, K.2
Phillips III, J.3
Prince, M.4
Markin, C.5
Speer, M.6
-
97
-
-
9744272376
-
Cigarette smoke induces senescence in alveolar epithelial cells
-
doi: 10.1165/rcmb.2003-0290OC
-
Tsuji, T., Aoshiba, K., and Nagai, A. (2004). Cigarette smoke induces senescence in alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 31, 643-649. doi: 10.1165/rcmb.2003-0290OC.
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.31
, pp. 643-649
-
-
Tsuji, T.1
Aoshiba, K.2
Nagai, A.3
-
98
-
-
0033765017
-
Involvement of Epstein-Barr virus latent membrane protein 1 in disease progression in patients with idiopathic pulmonary fibrosis
-
doi: 10.1136/thorax.55.11.958
-
Tsukamoto, K., Hayakawa, H., Sato, A., Chida, K., Nakamura, H., and Miura, K. (2000). Involvement of Epstein-Barr virus latent membrane protein 1 in disease progression in patients with idiopathic pulmonary fibrosis. Thorax 55, 958-961. doi: 10.1136/thorax.55.11.958.
-
(2000)
Thorax
, vol.55
, pp. 958-961
-
-
Tsukamoto, K.1
Hayakawa, H.2
Sato, A.3
Chida, K.4
Nakamura, H.5
Miura, K.6
-
99
-
-
78751489990
-
The airway epithelium: soldier in the fight against respiratory viruses
-
doi: 10.1128/CMR.00014-10
-
Vareille, M., Kieninger, E., Edwards, M. R., and Regamey, N. (2011). The airway epithelium: soldier in the fight against respiratory viruses. Clin. Microbiol. Rev. 24, 210-229. doi: 10.1128/CMR.00014-10.
-
(2011)
Clin. Microbiol. Rev.
, vol.24
, pp. 210-229
-
-
Vareille, M.1
Kieninger, E.2
Edwards, M.R.3
Regamey, N.4
-
100
-
-
18144371956
-
Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
-
Waghray, M., Cui, Z., Horowitz, J. C., Subramanian, I. M., Martinez, F. J., Toews, G. B., et al. (2005). Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J. 19, 854-856.
-
(2005)
FASEB J.
, vol.19
, pp. 854-856
-
-
Waghray, M.1
Cui, Z.2
Horowitz, J.C.3
Subramanian, I.M.4
Martinez, F.J.5
Toews, G.B.6
-
101
-
-
33744944779
-
Epithelial origin of myofibroblasts during fibrosis in the lung
-
doi: 10.1513/pats.200601-004TK
-
Willis, B. C., duBois, R. M., and Borok, Z. (2006). Epithelial origin of myofibroblasts during fibrosis in the lung. Proc. Am. Thorac. Soc. 3, 377-3782. doi: 10.1513/pats.200601-004TK.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 377-3782
-
-
Willis, B.C.1
duBois, R.M.2
Borok, Z.3
-
102
-
-
60649102339
-
Pulmonary fibrosis: pathogenesis, etiology and regulation
-
doi: 10.1038/mi.2008.85
-
Wilson, M. S., and Wynn, T. A. (2009). Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol. 2, 103-121. doi: 10.1038/mi.2008.85.
-
(2009)
Mucosal Immunol.
, vol.2
, pp. 103-121
-
-
Wilson, M.S.1
Wynn, T.A.2
-
103
-
-
79960381007
-
Integrating mechanisms of pulmonary fibrosis
-
doi: 10.1084/jem.20110551
-
Wynn, T. A. (2011). Integrating mechanisms of pulmonary fibrosis. J. Exp. Med. 208, 1339-1350. doi: 10.1084/jem.20110551.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1339-1350
-
-
Wynn, T.A.1
-
104
-
-
84863702343
-
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
-
doi: 10.1038/nm.2807
-
Wynn, T. A., and Ramalingam, T. R. (2012). Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat. Med. 18, 1028-1040. doi: 10.1038/nm.2807.
-
(2012)
Nat. Med.
, vol.18
, pp. 1028-1040
-
-
Wynn, T.A.1
Ramalingam, T.R.2
-
105
-
-
67649651896
-
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice
-
doi: 10.1093/gerona/glp040
-
Xu, J., Gonzalez, E. T., Iyer, S. S., Mac, V., Mora, A. L., Sutliff, R. L., et al. (2009). Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice. J. Gerontol. A Biol. Sci. Med. Sci. 64, 731-739. doi: 10.1093/gerona/glp040.
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 731-739
-
-
Xu, J.1
Gonzalez, E.T.2
Iyer, S.S.3
Mac, V.4
Mora, A.L.5
Sutliff, R.L.6
-
106
-
-
59849084848
-
Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironment
-
Yang, H. Z., Cui, B., Liu, H. Z., Chen, Z. R., Yan, H. M., Hua, F., et al. (2009). Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironment. J. Immunol. 182, 692-702.
-
(2009)
J. Immunol.
, vol.182
, pp. 692-702
-
-
Yang, H.Z.1
Cui, B.2
Liu, H.Z.3
Chen, Z.R.4
Yan, H.M.5
Hua, F.6
-
107
-
-
84887454672
-
Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis
-
doi: 10.1136/thoraxjnl-2012-202943
-
Yang, I. V., Coldren, C. D., Leach, S. M., Seibold, M. A., Murphy, E., Lin, J., et al. (2013). Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax 68, 1114-1121. doi: 10.1136/thoraxjnl-2012-202943.
-
(2013)
Thorax
, vol.68
, pp. 1114-1121
-
-
Yang, I.V.1
Coldren, C.D.2
Leach, S.M.3
Seibold, M.A.4
Murphy, E.5
Lin, J.6
|