Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis

European Journal of Clinical Investigation

Volumn 36, Issue 5, 2006, Pages 362-367

  Psathakis, K ^a   Mermigkis, D ^b   Papatheodorou, G ^a   Loukides, S ^a   Panagou, P ^a   Polychronopoulos, V ^b   Siafakas, N M ^c   Bouros, D ^d  

^a KAT HOSPITAL   (Greece)

^b SISMANOGLIO HOSPITAL   (Greece)

^c UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^d DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

8 isoprostane; Expired breath condensate; H2O2; IPF; Oxidative stress

Indexed keywords

8 ISOPROSTANE; BIOLOGICAL MARKER; CARBON MONOXIDE; HYDROGEN PEROXIDE; OXYGEN;

ADULT; AGED; ARTICLE; BREATHING; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; HEALTH STATUS; HUMAN; HUMAN CELL; IDIOPATHIC DISEASE; LEUKOCYTE DIFFERENTIAL COUNT; LUNG FIBROSIS; LUNG FUNCTION TEST; LUNG LAVAGE; OXIDATIVE STRESS; OXYGEN TENSION; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BREATH TESTS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; DINOPROST; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; HYDROGEN PEROXIDE; MALE; MIDDLE AGED; OXIDATIVE STRESS; PULMONARY FIBROSIS; RESPIRATORY FUNCTION TESTS; TOTAL LUNG CAPACITY;

EID: 33645845729     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2006.01636.x     Document Type: Article

References (29)

1. Khalil N O'Connor R Idiopathic pulmonary fibrosis: current understanding of the pathogenesis and the status of treatment CMAJ 2004 171 153 60
2. King TE Costabel U Cordier JF DoPico GA duBois RM Lynch D et al. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement Am J Respir Crit Care Med 2000 161 646 64
3. Verleden GM du Bois RM Bouros D Drent M Millar A Muller-Quernheim J et al. Genetic predisposition and pathogenetic mechanisms of interstitial lung diseases of unknown origin Eur Respir J 2001 18 Suppl. 32 17s 29s
4. McCord JM The evolution of free radicals and oxidative stress Am J Med 2000 108 652 9
5. Young IS Woodside JV Antioxidants in health and disease J Clin Pathol 2001 54 176 86
6. Mastruzzo C Crimi N Vancheri C Role of oxidative stress in pulmonary fibrosis Monaldi Arch Chest Dis 2002 57 173 6
7. Kinnula VL Fattman CL Tan RJ Oury TD Oxidative stress in pulmonary fibrosis. A possible role for redox modulatory therapy Am J Respir Crit Care Med 2005 172 417 22
8. Morrow JD Roberts LJ The isoprostanes. Their role as an index of oxidant stress status in human pulmonary disease Am J Respir Crit Care Med 2002 166 s25 s30
9. Lenz A-G Costabel U Maier KL Oxidized BAL fluid proteins in patients with interstitial lung diseases Eur Respir J 1996 9 307 12
10. Montuschi P Ciabattoni G Paredi P Pantelidis P duBois RM Kharitonov SA et al. 8-isoprostane as a biomarker of oxidative stress in interstitial lung diseases Am J Respir Crit Care Med 1998 158 1524 7
11. Psathakis K Papatheodorou G Plataki M Panagou P Loukides S Siafakas NM et al. 8-isoprostane, a marker of oxidative stress, is increased in the expired breath condensate of patients with pulmonary sarcoidosis Chest 2004 125 1005 11
12. Kostikas K Papatheodorou G Psathakis K Panagou P Loukides S Oxidative stress in expired breath condensate of patients with COPD Chest 2003 124 1373 80
13. Ganas K Loukides S Papatheodorou G Panagou P Kalogeropoulos N Total nitrite/nitrate in the expired breath condensate of patients with asthma Respir Med 2001 95 649 54
14. 2 and 3, 3′, 5, 5′-tetramethylbenzidine J Clin Chem Clin Biochem 1985 23 453 60
15. Montuschi P Corradi M Ciabattoni G Nightingale J Kharitonov SA Barnes PJ Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients Am J Respir Crit Care Med 1999 160 216 20
16. Bland JM Altman DG Statistical methods for assessing agreement between two methods of clinical measurement Lancet 1986 1 307 10
17. Selman M King TE Pardo A Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy Ann Intern Med 2001 134 136 51
18. Rochelle LG Fischer BM Adler KB Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro Free Radic Biol Med 1998 24 863 4
19. Rahman I MacNee W Oxidative stress and regulation of glutathione in lung inflammation Eur Respir J 2000 16 534 54
20. Rahman I Skwarska E Henry M Davis M O'Connor CM FitzGerald MX et al. Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis Free Radic Biol Med 1999 27 60 8
21. Demedts M Behr J Buhl R Costabel U Dekhuijzen R Jansen HM et al. High-dose acetylcysteine in idiopathic pulmonary fibrosis N Engl J Med 2005 353 2229 42
22. Horvath I Hunt J Barnes PJ Exhaled breath condensate: methodological recommendations and unresolved questions Eur Respir J 2005 26 523 48
23. Van Hoydonck PGA Wuyts WA Vanaudenaerde BM Schouten EG Dupont LJ Temme EH Quantitative analysis of 8-isoprostane and hydrogen peroxide in exhaled breath condensate Eur Respir J 2004 23 189 92
24. Rahman I Kelly F Biomarkers in breath condensate: a promising new non-invasive technique in free radical research Free Radic Res 2003 37 1253 66
25. 2 and thiobarbituric acid reactive substances (TBARs) by healthy subjects Free Radic Biol Med 2001 30 178 86
26. Jobsis Q Raatgeep HC Schellekens SL Hop WCJ Hermans PWM de Jongste JC Hydrogen peroxide in exhaled air of healthy children: reference values Eur Respir J 1998 12 483 5
27. Montuschi P Collins JV Ciabattoni G Lazzeri N Corradi M Kharitonov SA et al. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers Am J Respir Crit Care Med 2000 162 1175 7
28. Hunninghake GW Antioxidant therapy for idiopathic pulmonary fibrosis N Engl J Med 2005 353 2285 7
29. Tomioka H Kuwata Y Imanaka K Hashimoto K Ohnishi H Tada K et al. A pilot study of aerosolized N-acetylcysteine for idiopathic pulmonary fibrosis Respirology 2005 10 449 55