Transcriptional activation of mucin by pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 3, 1997, Pages 967-972

  Li, Jian Dong ^a,b   Dohrman, Austin F ^a,b   Gallup, Marianne ^a,b   Miyata, Susumu ^a,b   Gum, James R ^a,b   Kim, Young S ^a,b   Nadel, Jay A ^a,b   Prince, Alice ^c   Basbaum, Carol B ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

CFTR; endotoxin; MUC 2 gene; protein tyrosine phosphorylation

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHLORIDE CHANNEL; GENISTEIN; MUCIN; PROTEIN TYROSINE KINASE INHIBITOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; TYRPHOSTIN;

ARTICLE; BRONCHUS MUCUS; CONTROLLED STUDY; CYSTIC FIBROSIS; ENHANCER REGION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; RESPIRATORY EPITHELIUM; TRANSCRIPTION REGULATION;

BENZYLIDENE COMPOUNDS; BRONCHI; CELL LINE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME INHIBITORS; EPITHELIUM; HUMANS; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; MUCINS; NITRILES; PROTEIN-TYROSINE KINASES; PSEUDOMONAS AERUGINOSA; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TYRPHOSTINS;

EID: 0031029855     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.3.967     Document Type: Article

References (23)

1. Collins, F. S. & Wilson, J. M. (1992) Nature (London) 358, 708-709.
2. Saiman, L. & Prince, A. (1993) J. Clin. Invest. 92, 1875-18810.
3. Pier, G. B., Grout, M., Zaidi, T. S., Olsen, J. C., Johnson, L. G., Yankaskas, J. R. & Goldberg, J. B. (1996) Science 271, 64-67.
4. Smith, J. J., Travis, S. M., Greenberg, E. P. & Welsh, M. J. (1996) Cell 85, 229-236.
5. Matthews, L. (1963) Am. Rev. Respir. Dis. 88, 199-207.
6. Coyne, M. J., Kristin, J. R., Russell, S., Coyle, C. L. & Goldberg, J. B. (1994) J. Bacteriol. 176, 3500-3507.
7. Dohrman, A. & Basbaum, C. B. (1994) Exp. Lung Res. 20, 367-382.
8. Dohrman, A. & Basbaum, C. B. (1995) Respir. Crit. Care Med. 151, A160 (abstr.).
9. Gum, J. R., Hicks, J. W., Toribara, N. W., Siddiki, B. & Kim, Y. S. (1994) J. Biol. Chem. 269, 2440-2446.
10. Hiro, K., Takeuchi, K., Ohmori, H, Li, J. D., Gallup, M. & Basbaum C. B. (1996) J. Cell. Biochem. 61, 350-362.
11. Gum, J. R., Byrd, J. C., Hicks, J. W., Toribara, N. W., Lamport, D. T. A. & Kim, Y. S. (1989) J. Biol. Chem. 264, 6480-6487.
12. Boat, T. & Boucher, R. (1994) in Textbook of Respiratory Medicine, eds. Murray, J. & Nadel, J. (Saunders, Philadelphia), pp. 1418-1450.
13. DiMango, E., Zar, H. J., Bryan, R. & Prince, A. (1995) J. Clin. Invest. 96, 2204-2210.
14. Gambello, M. J. & Iglewski, B. H. (1991) J. Bacteriol. 173, 3000-3009.
15. Pearson, J. P., Gray, K. M., Passador, L., Tucker, K. D., Eberhard, A., Iglewski, B. H. & Greenberg, E. P. (1994) Proc. Natl. Acad. Sci. USA 91, 197-201.
16. Cacalano, G., Kays, M., Saiman, L. & Prince, A. (1992) J. Clin. Invest. 89, 1866-1874.
17. Drake, D. & Montie, T. C. (1988) J. Gen. Microbiol. 134, 43-52.
18. Weinstein, S. L, Sanghera, G. S., Lemke, K., DeFranco, A. L. & Pelech, S. L. (1992) J. Biol. Chem. 267, 14955-14962.
19. Ractz, C. (1990) Annu. Rev. Biochem. 59, 129-141.
20. Tang, H. B., DiMango, E., Bryan, R., Gambello, M., Iglewski, B. H., Goldberg, J. B. & Prince, A. (1996) Infect. Immun. 64, 37-43.
21. Novogrodsky, A., Vanichkin, A., Patya, M., Gazit, A., Osherov, N. & Levitzki, A. (1996) Science 264, 1319-1322.
22. Lynn, W. A. & Golenboch, D. T. (1992) Immunol. Today 13, 271-276.
23. Levitzki, A. & Gazit, A. (1995) Science 267, 1782-1788.