Proteolytic activation of latent TGF-β precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells

Journal of Cellular Physiology

Volumn 207, Issue 2, 2006, Pages 445-453

  Solovyan, Victor T ^a,b   Keski Oja, Jorma ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOKINE; LARGE LATENT TRANSFORMING GROWTH FACTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE PROTEINASE INHIBITOR; STAUROSPORINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; EPITHELIUM CELL; EVALUATION; EXTRACELLULAR MATRIX; LUNG ALVEOLUS EPITHELIUM; MINK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SERUM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL ADHESION; CELL LINE; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; CULTURE MEDIA, SERUM-FREE; EPITHELIAL CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LATENT TGF-BETA BINDING PROTEINS; LUNG; MINK; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTO-ONCOGENE PROTEINS C-AKT; SMAD2 PROTEIN; STAUROSPORINE; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA; MUSTELA VISON;

EID: 33645659496     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20607     Document Type: Article

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