메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

A network pharmacology approach to determine active compounds and action mechanisms of Ge-Gen-Qin-Lian decoction for treatment of type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84893786240     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2014/495840     Document Type: Article
Times cited : (163)

References (69)
  • 1
    • 85081804798 scopus 로고    scopus 로고
    • IDF diabetes atlas
    • International Federation of Diabetes,. IDF diabetes atlas, http://www.diabetesatlas.org/
    • Federation Of Diabetes, I.1
  • 2
    • 84858383401 scopus 로고    scopus 로고
    • Diabetes mellitus and the β cell: The last ten years
    • 2-s2.0-84858383401 10.1016/j.cell.2012.02.010
    • Ashcroft F. M., Rorsman P., Diabetes mellitus and the β cell: the last ten years. Cell 2012 148 6 1160 1171 2-s2.0-84858383401 10.1016/j.cell.2012.02.010
    • (2012) Cell , vol.148 , Issue.6 , pp. 1160-1171
    • Ashcroft, F.M.1    Rorsman, P.2
  • 3
    • 0032489358 scopus 로고    scopus 로고
    • Type 2 diabetes: When insulin secretion fails to compensate for insulin resistance
    • DOI 10.1016/S0092-8674(00)81125-3
    • Kahn B. B., Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 1998 92 5 593 596 2-s2.0-0032489358 10.1016/S0092-8674(00)81125-3 (Pubitemid 28141507)
    • (1998) Cell , vol.92 , Issue.5 , pp. 593-596
    • Kahn, B.B.1
  • 4
    • 0026969347 scopus 로고
    • Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM)
    • Hamman R. F., Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM). Diabetes/Metabolism Reviews 1992 8 4 287 338 2-s2.0-0026969347 (Pubitemid 23171181)
    • (1992) Diabetes/Metabolism Reviews , vol.8 , Issue.4 , pp. 287-338
    • Hamman, R.F.1
  • 5
    • 77956266047 scopus 로고    scopus 로고
    • The emerging genetics of type 2 diabetes
    • 2-s2.0-77956266047 10.1016/j.molmed.2010.06.004
    • Bonnefond A., Froguel P., Vaxillaire M., The emerging genetics of type 2 diabetes. Trends in Molecular Medicine 2010 16 9 407 416 2-s2.0-77956266047 10.1016/j.molmed.2010.06.004
    • (2010) Trends in Molecular Medicine , vol.16 , Issue.9 , pp. 407-416
    • Bonnefond, A.1    Froguel, P.2    Vaxillaire, M.3
  • 6
    • 56349158387 scopus 로고    scopus 로고
    • Type 2 diabetes: New genes, new understanding
    • 2-s2.0-56349158387 10.1016/j.tig.2008.09.004
    • Prokopenko I., McCarthy M. I., Lindgren C. M., Type 2 diabetes: new genes, new understanding. Trends in Genetics 2008 24 12 613 621 2-s2.0-56349158387 10.1016/j.tig.2008.09.004
    • (2008) Trends in Genetics , vol.24 , Issue.12 , pp. 613-621
    • Prokopenko, I.1    McCarthy, M.I.2    Lindgren, C.M.3
  • 7
    • 79960913754 scopus 로고    scopus 로고
    • Emerging roles of JAK-STAT signaling pathways in adipocytes
    • 2-s2.0-79960913754 10.1016/j.tem.2011.03.007
    • Richard A. J., Stephens J. M., Emerging roles of JAK-STAT signaling pathways in adipocytes. Trends in Endocrinology and Metabolism 2011 22 8 325 332 2-s2.0-79960913754 10.1016/j.tem.2011.03.007
    • (2011) Trends in Endocrinology and Metabolism , vol.22 , Issue.8 , pp. 325-332
    • Richard, A.J.1    Stephens, J.M.2
  • 8
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • 2-s2.0-84857861919 10.1016/j.cell.2012.02.017
    • Samuel V. T., Shulman G. I., Mechanisms for insulin resistance: common threads and missing links. Cell 2012 148 5 852 871 2-s2.0-84857861919 10.1016/j.cell.2012.02.017
    • (2012) Cell , vol.148 , Issue.5 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 9
    • 55649098154 scopus 로고    scopus 로고
    • Wnt signaling: Relevance to β -cell biology and diabetes
    • 2-s2.0-55649098154 10.1016/j.tem.2008.08.004
    • Welters H. J., Kulkarni R. N., Wnt signaling: relevance to β -cell biology and diabetes. Trends in Endocrinology and Metabolism 2008 19 10 349 355 2-s2.0-55649098154 10.1016/j.tem.2008.08.004
    • (2008) Trends in Endocrinology and Metabolism , vol.19 , Issue.10 , pp. 349-355
    • Welters, H.J.1    Kulkarni, R.N.2
  • 10
    • 0038408484 scopus 로고    scopus 로고
    • Novel targets and therapeutic strategies for type 2 diabetes
    • DOI 10.1016/S1043-2760(03)00031-6
    • Morral N., Novel targets and therapeutic strategies for type 2 diabetes. Trends in Endocrinology and Metabolism 2003 14 4 169 175 2-s2.0-0038408484 10.1016/S1043-2760(03)00031-6 (Pubitemid 36733902)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.4 , pp. 169-175
    • Morral, N.1
  • 11
    • 0030860790 scopus 로고    scopus 로고
    • New concepts for treatment of non-insulin-dependent diabetes mellitus
    • DOI 10.1016/S1043-2760(97)00037-4, PII S1043276097000374
    • Larkins R. G., New concepts for treatment of non-insulin-dependent diabetes mellitus. Trends in Endocrinology and Metabolism 1997 8 5 187 191 2-s2.0-0030860790 10.1016/S1043-2760(97)00037-4 (Pubitemid 27343845)
    • (1997) Trends in Endocrinology and Metabolism , vol.8 , Issue.5 , pp. 187-191
    • Larkins, R.G.1
  • 12
    • 77649182705 scopus 로고    scopus 로고
    • Unveiling the role of network and systems biology in drug discovery
    • 2-s2.0-77649182705 10.1016/j.tips.2009.11.006
    • Pujol A., Mosca R., Farrés J., Aloy P., Unveiling the role of network and systems biology in drug discovery. Trends in Pharmacological Sciences 2010 31 3 115 123 2-s2.0-77649182705 10.1016/j.tips.2009.11.006
    • (2010) Trends in Pharmacological Sciences , vol.31 , Issue.3 , pp. 115-123
    • Pujol, A.1    Mosca, R.2    Farrés, J.3    Aloy, P.4
  • 15
    • 78049259598 scopus 로고    scopus 로고
    • Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet
    • 2-s2.0-78049259598 10.1016/j.ejphar.2010.09.054
    • Zhang W., Liu C.-Q., Wang P.-W., Sun S.-Y., Su W.-J., Zhang H.-J., Li X.-J., Yang S.-Y., Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet. European Journal of Pharmacology 2010 649 1-3 398 402 2-s2.0-78049259598 10.1016/j.ejphar.2010.09.054
    • (2010) European Journal of Pharmacology , vol.649 , Issue.1-3 , pp. 398-402
    • Zhang, W.1    Liu, C.-Q.2    Wang, P.-W.3    Sun, S.-Y.4    Su, W.-J.5    Zhang, H.-J.6    Li, X.-J.7    Yang, S.-Y.8
  • 16
    • 0038204299 scopus 로고    scopus 로고
    • Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats
    • Hsu F.-L., Liu I.-M., Kuo D.-H., Chen W.-C., Su H.-C., Cheng J.-T., Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. Journal of Natural Products 2003 66 6 788 792 2-s2.0-0038204299 (Pubitemid 36782086)
    • (2003) Journal of Natural Products , vol.66 , Issue.6 , pp. 788-792
    • Hsu, F.-L.1    Liu, I.-M.2    Kuo, D.-H.3    Chen, W.-C.4    Su, H.-C.5    Cheng, J.-T.6
  • 17
    • 85081803275 scopus 로고    scopus 로고
    • Puerarin reduces blood sugar in the diabetic mice and improves hyperlipidemia in rats
    • Liu Y. M., Feng Q. J., Niu X., Song Q., Zhang X., Kang Y. M., Puerarin reduces blood sugar in the diabetic mice and improves hyperlipidemia in rats. The FASEB Journal 2006 20 A298
    • (2006) The FASEB Journal , vol.20
    • Liu, Y.M.1    Feng, Q.J.2    Niu, X.3    Song, Q.4    Zhang, X.5    Kang, Y.M.6
  • 18
    • 79551665811 scopus 로고    scopus 로고
    • Antihyperglycemic effects of baicalin on streptozotocin - Nicotinamide induced diabetic rats
    • 2-s2.0-79551665811 10.1002/ptr.3238
    • Li H.-T., Wu X.-D., Davey A. K., Wang J., Antihyperglycemic effects of baicalin on streptozotocin-nicotinamide induced diabetic rats. Phytotherapy Research 2011 25 2 189 194 2-s2.0-79551665811 10.1002/ptr.3238
    • (2011) Phytotherapy Research , vol.25 , Issue.2 , pp. 189-194
    • Li, H.-T.1    Wu, X.-D.2    Davey, A.K.3    Wang, J.4
  • 19
    • 74049139484 scopus 로고    scopus 로고
    • Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression
    • 2-s2.0-74049139484 10.1016/j.metabol.2009.07.029
    • Zhang H., Wei J., Xue R., Wu J.-D., Zhao W., Wang Z.-Z., Wang S.-K., Zhou Z.-X., Song D.-Q., Wang Y.-M., Pan H.-N., Kong W.-J., Jiang J.-D., Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism 2010 59 2 285 292 2-s2.0-74049139484 10.1016/j.metabol.2009.07.029
    • (2010) Metabolism , vol.59 , Issue.2 , pp. 285-292
    • Zhang, H.1    Wei, J.2    Xue, R.3    Wu, J.-D.4    Zhao, W.5    Wang, Z.-Z.6    Wang, S.-K.7    Zhou, Z.-X.8    Song, D.-Q.9    Wang, Y.-M.10    Pan, H.-N.11    Kong, W.-J.12    Jiang, J.-D.13
  • 21
    • 79956141290 scopus 로고    scopus 로고
    • Clinical observations on the dose-effect relationship of Gegen Qin Lian Decoction on 54 out-patients with type 2 diabetes
    • 2-s2.0-79956141290
    • Tong X.-L., Zhao L.-H., Lian F.-M., Zhou Q., Xia L., Zhang J.-C., Chen X.-Y., Ji H.-Y., Clinical observations on the dose-effect relationship of Gegen Qin Lian Decoction on 54 out-patients with type 2 diabetes. Journal of Traditional Chinese Medicine 2011 31 1 56 59 2-s2.0-79956141290
    • (2011) Journal of Traditional Chinese Medicine , vol.31 , Issue.1 , pp. 56-59
    • Tong, X.-L.1    Zhao, L.-H.2    Lian, F.-M.3    Zhou, Q.4    Xia, L.5    Zhang, J.-C.6    Chen, X.-Y.7    Ji, H.-Y.8
  • 22
    • 84873714741 scopus 로고    scopus 로고
    • Anti-diabetic activities of Ge-Gen-Qin-Lian Decoction in high-fat diet combined with streptozotocin-induced diabetic rats and in 3T-L1 adipocytes
    • Zhang C. H., Xu G. L., Liu Y. H., Rao Y., Yu R. Y., Zhang Z. W., Wang Y. S., Tao L., Anti-diabetic activities of Ge-Gen-Qin-Lian Decoction in high-fat diet combined with streptozotocin-induced diabetic rats and in 3T-L1 adipocytes. Phytomedicine 2013 20 3-4 3221 3229
    • (2013) Phytomedicine , vol.20 , Issue.3-4 , pp. 3221-3229
    • Zhang, C.H.1    Xu, G.L.2    Liu, Y.H.3    Rao, Y.4    Yu, R.Y.5    Zhang, Z.W.6    Wang, Y.S.7    Tao, L.8
  • 24
    • 43049158125 scopus 로고    scopus 로고
    • Designing transient binding drugs: A new concept for drug discovery
    • 2-s2.0-43049158125 10.1016/j.drudis.2008.02.001
    • Ohlson S., Designing transient binding drugs: a new concept for drug discovery. Drug Discovery Today 2008 13 9-10 433 439 2-s2.0-43049158125 10.1016/j.drudis.2008.02.001
    • (2008) Drug Discovery Today , vol.13 , Issue.9-10 , pp. 433-439
    • Ohlson, S.1
  • 25
    • 84879147636 scopus 로고    scopus 로고
    • Traditional Chinese medicine network pharmacology: Theory, methodology and application
    • Li S., Zhang B., Traditional Chinese medicine network pharmacology: theory, methodology and application. Chinese Journal of Natural Medicines 2013 11 2 110 120
    • (2013) Chinese Journal of Natural Medicines , vol.11 , Issue.2 , pp. 110-120
    • Li, S.1    Zhang, B.2
  • 26
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: The next paradigm in drug discovery
    • 2-s2.0-54249155522 10.1038/nchembio.118
    • Hopkins A. L., Network pharmacology: the next paradigm in drug discovery. Nature Chemical Biology 2008 4 11 682 690 2-s2.0-54249155522 10.1038/nchembio.118
    • (2008) Nature Chemical Biology , vol.4 , Issue.11 , pp. 682-690
    • Hopkins, A.L.1
  • 27
    • 34249037449 scopus 로고    scopus 로고
    • Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network
    • DOI 10.1049/iet-syb:20060032
    • Li S., Zhang Z. Q., Wu L. J., Zhang X. G., Li Y. D., Wang Y. Y., Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network. IET Systems Biology 2007 1 1 51 60 2-s2.0-34249037449 10.1049/iet-syb:20060032 (Pubitemid 46779218)
    • (2007) IET Systems Biology , vol.1 , Issue.1 , pp. 51-60
    • Li, S.1    Zhang, Z.Q.2    Wu, L.J.3    Zhang, X.G.4    Li, Y.D.5    Wang, Y.Y.6
  • 28
    • 34648827366 scopus 로고    scopus 로고
    • Framework and practice of network-based studies for Chinese herbal formula
    • DOI 10.3736/jcim20070501
    • Li S., Framework and practice of network-based studies for Chinese herbal formula. Journal of Chinese Integrative Medicine 2007 5 5 489 493 2-s2.0-34648827366 10.3736/jcim20070501 (Pubitemid 47455595)
    • (2007) Journal of Chinese Integrative Medicine , vol.5 , Issue.5 , pp. 489-493
    • Li, S.1
  • 29
    • 70549112019 scopus 로고    scopus 로고
    • Network systems underlying traditional Chinese medicine syndrome and herb formula
    • 2-s2.0-70549112019 10.2174/157489309789071129
    • Li S., Network systems underlying traditional Chinese medicine syndrome and herb formula. Current Bioinformatics 2009 4 3 188 196 2-s2.0-70549112019 10.2174/157489309789071129
    • (2009) Current Bioinformatics , vol.4 , Issue.3 , pp. 188-196
    • Li, S.1
  • 30
    • 78650832745 scopus 로고    scopus 로고
    • Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae
    • supplement 11, article S6 2-s2.0-78650832745 10.1186/1471-2105-11-S11-S6
    • Li S., Zhang B., Jiang D., Wei Y., Zhang N., Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics 2010 11 supplement 11, article S6 2-s2.0-78650832745 10.1186/1471-2105-11-S11-S6
    • (2010) BMC Bioinformatics , vol.11
    • Li, S.1    Zhang, B.2    Jiang, D.3    Wei, Y.4    Zhang, N.5
  • 31
    • 80053964470 scopus 로고    scopus 로고
    • Network target: A starting point for traditional Chinese medicine network pharmacology
    • 2-s2.0-80053964470 10.4268/cjcmm20111502
    • Li S., Network target: a starting point for traditional Chinese medicine network pharmacology. Zhongguo Zhongyao Zazhi 2011 36 15 2017 2020 2-s2.0-80053964470 10.4268/cjcmm20111502
    • (2011) Zhongguo Zhongyao Zazhi , vol.36 , Issue.15 , pp. 2017-2020
    • Li, S.1
  • 32
    • 79959199033 scopus 로고    scopus 로고
    • Network target for screening synergistic drug combinations with application to traditional Chinese medicine
    • supplement 1, article S10 2-s2.0-79959199033 10.1186/1752-0509-5-S1-S10
    • Li S., Zhang B., Zhang N., Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC Systems Biology 2011 5 supplement 1, article S10 2-s2.0-79959199033 10.1186/1752-0509-5- S1-S10
    • (2011) BMC Systems Biology , vol.5
    • Li, S.1    Zhang, B.2    Zhang, N.3
  • 34
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and centrality in protein networks
    • DOI 10.1038/35075138
    • Jeong H., Mason S. P., Barabási A.-L., Oltvai Z. N., Lethality and centrality in protein networks. Nature 2001 411 6833 41 42 2-s2.0-0035799707 10.1038/35075138 (Pubitemid 32428180)
    • (2001) Nature , vol.411 , Issue.6833 , pp. 41-42
    • Jeong, H.1    Mason, S.P.2    Barabasi, A.-L.3    Oltvai, Z.N.4
  • 35
    • 0033518234 scopus 로고    scopus 로고
    • From molecular to modular cell biology
    • 2-s2.0-0033518234
    • Hartwell L. H., Hopfield J. J., Leibler S., Murray A. W., From molecular to modular cell biology. Nature 1999 402 6761 C47 C52 2-s2.0-0033518234
    • (1999) Nature , vol.402 , Issue.6761
    • Hartwell, L.H.1    Hopfield, J.J.2    Leibler, S.3    Murray, A.W.4
  • 36
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • 2-s2.0-65949107547 10.1056/NEJMp0806284
    • Goldstein D. B., Common genetic variation and human traits. New England Journal of Medicine 2009 360 17 1696 1698 2-s2.0-65949107547 10.1056/NEJMp0806284
    • (2009) New England Journal of Medicine , vol.360 , Issue.17 , pp. 1696-1698
    • Goldstein, D.B.1
  • 37
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • 2-s2.0-70249134919 10.1038/nature08454
    • Schadt E. E., Molecular networks as sensors and drivers of common human diseases. Nature 2009 461 7261 218 223 2-s2.0-70249134919 10.1038/nature08454
    • (2009) Nature , vol.461 , Issue.7261 , pp. 218-223
    • Schadt, E.E.1
  • 38
    • 84877278297 scopus 로고    scopus 로고
    • An integrative platform of TCM network pharmacology and its application on a Herbal Formula, Qing-Luo-Yin
    • 456747 10.1155/2013/456747
    • Zhang B., Wang X., Li S., An integrative platform of TCM network pharmacology and its application on a Herbal Formula, Qing-Luo-Yin. Evidence-Based Complementary and Alternative Medicine 2013 2013 12 456747 10.1155/2013/456747
    • (2013) Evidence-Based Complementary and Alternative Medicine , vol.2013 , pp. 12
    • Zhang, B.1    Wang, X.2    Li, S.3
  • 39
    • 67849104638 scopus 로고    scopus 로고
    • PubChem: A public information system for analyzing bioactivities of small molecules
    • 2-s2.0-67849104638 10.1093/nar/gkp456
    • Wang Y., Xiao J., Suzek T. O., Zhang J., Wang J., Bryant S. H., PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Research 2009 37 2 W623 W633 2-s2.0-67849104638 10.1093/nar/gkp456
    • (2009) Nucleic Acids Research , vol.37 , Issue.2
    • Wang, Y.1    Xiao, J.2    Suzek, T.O.3    Zhang, J.4    Wang, J.5    Bryant, S.H.6
  • 40
    • 13444266370 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
    • DOI 10.1093/nar/gki033
    • Hamosh A., Scott A. F., Amberger J. S., Bocchini C. A., McKusick V. A., Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Research 2005 33 D514 D517 2-s2.0-13444266370 10.1093/nar/gki033 (Pubitemid 40207927)
    • (2005) Nucleic Acids Research , vol.33 , Issue.DATABASE ISS.
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.S.3    Bocchini, C.A.4    McKusick, V.A.5
  • 42
    • 77955628292 scopus 로고    scopus 로고
    • Network-based relating pharmacological and genomic spaces for drug target identification
    • 2-s2.0-77955628292 10.1371/journal.pone.0011764 e11764
    • Zhao S., Li S., Network-based relating pharmacological and genomic spaces for drug target identification. PLoS ONE 2010 5 7 2-s2.0-77955628292 10.1371/journal.pone.0011764 e11764
    • (2010) PLoS ONE , vol.5 , Issue.7
    • Zhao, S.1    Li, S.2
  • 43
    • 0347473810 scopus 로고    scopus 로고
    • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
    • DOI 10.1038/nbt919
    • Parsons A. B., Brost R. L., Ding H., Li Z., Zhang C., Sheikh B., Brown G. W., Kane P. M., Hughes T. R., Boone C., Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nature Biotechnology 2004 22 1 62 69 2-s2.0-0347473810 10.1038/nbt919 (Pubitemid 38057958)
    • (2004) Nature Biotechnology , vol.22 , Issue.1 , pp. 62-69
    • Parsons, A.B.1    Brost, R.L.2    Ding, H.3    Li, Z.4    Zhang, C.5    Sheikh, B.6    Brown, G.W.7    Kane, P.M.8    Hughes, T.R.9    Boone, C.10
  • 44
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • 2-s2.0-61449172037 10.1038/nprot.2008.211
    • Huang D. W., Sherman B. T., Lempicki R. A., Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 2009 4 1 44 57 2-s2.0-61449172037 10.1038/nprot.2008.211
    • (2009) Nature Protocols , vol.4 , Issue.1 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 45
    • 77957156174 scopus 로고    scopus 로고
    • Ranking effects of candidate drugs on biological process by integrating network analysis and Gene Ontology
    • 2-s2.0-77957156174 10.1007/s11434-010-4067-6
    • Li L. S., Zhang N. B., Li S., Ranking effects of candidate drugs on biological process by integrating network analysis and Gene Ontology. Chinese Science Bulletin 2010 55 26 2974 2980 2-s2.0-77957156174 10.1007/s11434-010- 4067-6
    • (2010) Chinese Science Bulletin , vol.55 , Issue.26 , pp. 2974-2980
    • Li, L.S.1    Zhang, N.B.2    Li, S.3
  • 46
    • 0018869666 scopus 로고
    • Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes
    • Kaiden Student A., Hsu R. Y., Lane M. D., Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. Journal of Biological Chemistry 1980 255 10 4745 4750 2-s2.0-0018869666 (Pubitemid 10060752)
    • (1980) Journal of Biological Chemistry , vol.255 , Issue.10 , pp. 4745-4750
    • Kaiden Student, A.1    Hsu, R.Y.2    Lane, M.D.3
  • 47
    • 0034079122 scopus 로고    scopus 로고
    • High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes
    • Nelson B. A., Robinson K. A., Buse M. G., High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes. Diabetes 2000 49 6 981 991 2-s2.0-0034079122 (Pubitemid 30349421)
    • (2000) Diabetes , vol.49 , Issue.6 , pp. 981-991
    • Nelson, B.A.1    Robinson, K.A.2    Buse, M.G.3
  • 48
    • 33847377573 scopus 로고    scopus 로고
    • A robustness-based approach to systems-oriented drug design
    • DOI 10.1038/nrd2195, PII NRD2195
    • Kitano H., A robustness-based approach to systems-oriented drug design. Nature Reviews Drug Discovery 2007 6 3 202 210 2-s2.0-33847377573 10.1038/nrd2195 (Pubitemid 46344624)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.3 , pp. 202-210
    • Kitano, H.1
  • 49
    • 33646241042 scopus 로고    scopus 로고
    • SciFinder Scholar 2006: An empirical analysis of research topic query processing
    • 2-s2.0-33646241042 10.1021/ci050481b
    • Wagner A. B., SciFinder Scholar 2006: an empirical analysis of research topic query processing. Journal of Chemical Information and Modeling 2006 46 2 767 774 2-s2.0-33646241042 10.1021/ci050481b
    • (2006) Journal of Chemical Information and Modeling , vol.46 , Issue.2 , pp. 767-774
    • Wagner, A.B.1
  • 50
    • 9644295898 scopus 로고    scopus 로고
    • Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties
    • DOI 10.1016/j.foodchem.2004.05.056, PII S030881460400456X
    • Lee S.-J., Umano K., Shibamoto T., Lee K.-G., Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties. Food Chemistry 2005 91 1 131 137 2-s2.0-9644295898 10.1016/j.foodchem.2004.05.056 (Pubitemid 39572542)
    • (2005) Food Chemistry , vol.91 , Issue.1 , pp. 131-137
    • Lee, S.-J.1    Umano, K.2    Shibamoto, T.3    Lee, K.-G.4
  • 52
    • 0042668497 scopus 로고    scopus 로고
    • Systematic review of herbs and dietary supplements for glycemic control in diabetes
    • DOI 10.2337/diacare.26.4.1277
    • Yeh G. Y., Eisenberg D. M., Kaptchuk T. J., Phillips R. S., Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003 26 4 1277 1294 2-s2.0-0042668497 10.2337/diacare.26.4.1277 (Pubitemid 36929285)
    • (2003) Diabetes Care , vol.26 , Issue.4 , pp. 1277-1294
    • Yeh, G.Y.1    Eisenberg, D.M.2    Kaptchuk, T.J.3    Phillips, R.S.4
  • 54
    • 84880095734 scopus 로고    scopus 로고
    • A traditional Chinese medicine JiuHuangLian (Rhizoma coptidis steamed with rice wine) reduces oxidative stress injury in type 2 diabetic rats
    • 10.1016/j.fct.2013.06.005
    • Li J. C., Shen X. F., Meng X. L., A traditional Chinese medicine JiuHuangLian (Rhizoma coptidis steamed with rice wine) reduces oxidative stress injury in type 2 diabetic rats. Food and Chemical Toxicology 2013 59 222 229 10.1016/j.fct.2013.06.005
    • (2013) Food and Chemical Toxicology , vol.59 , pp. 222-229
    • Li, J.C.1    Shen, X.F.2    Meng, X.L.3
  • 55
    • 84876284037 scopus 로고    scopus 로고
    • Isolation of Jatrorrhizine and Epiberberine in Coptis chinensis and their in vitro Hypoglycemic Effect
    • Jiang X. F., Wang L. J., Li X. G., Zhao Z. Q., Zhu J. Y., Isolation of Jatrorrhizine and Epiberberine in Coptis chinensis and their in vitro Hypoglycemic Effect. Guizhou Agricultural Sciences 2011 39 9 44 46
    • (2011) Guizhou Agricultural Sciences , vol.39 , Issue.9 , pp. 44-46
    • Jiang, X.F.1    Wang, L.J.2    Li, X.G.3    Zhao, Z.Q.4    Zhu, J.Y.5
  • 56
    • 33750543230 scopus 로고    scopus 로고
    • Effect of jatrorrhizine, berberine, Huanglian Decoction and compound-mimic prescription on blood glucose in mice
    • Fu Y., Hu B. R., Tang Q., Effect of jatrorrhizine, berberine, Huanglian Decoction and compound-mimic prescription on blood glucose in mice. Chinese Traditional and Herbal Drugs 2005 36 4 548 551
    • (2005) Chinese Traditional and Herbal Drugs , vol.36 , Issue.4 , pp. 548-551
    • Fu, Y.1    Hu, B.R.2    Tang, Q.3
  • 57
    • 13544254451 scopus 로고    scopus 로고
    • Antidiabetic activity of alcoholic stem extract of Coscinium fenestratum in streptozotocin-nicotinamide induced type 2 diabetic rats
    • DOI 10.1016/j.jep.2004.11.034
    • Shirwaikar A., Rajendran K., Punitha I. S. R., Antidiabetic activity of alcoholic stem extract of Coscinium fenestratum in streptozotocin-nicotinamide induced type 2 diabetic rats. Journal of Ethnopharmacology 2005 97 2 369 374 2-s2.0-13544254451 10.1016/j.jep.2004.11.034 (Pubitemid 40222041)
    • (2005) Journal of Ethnopharmacology , vol.97 , Issue.2 , pp. 369-374
    • Shirwaikar, A.1    Rajendran, K.2    Punitha, I.S.R.3
  • 59
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
    • DOI 10.2337/db06-0006
    • Lee Y. S., Kim W. S., Kim K. H., Yoon M. J., Cho H. J., Shen Y., Ye J.-M., Lee C. H., Oh W. K., Kim C. T., Hohnen-Behrens C., Gosby A., Kraegen E. W., James D. E., Kim J. B., Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006 55 8 2256 2264 2-s2.0-33749336146 10.2337/db06-0006 (Pubitemid 44743622)
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2256-2264
    • Lee, Y.S.1    Kim, W.S.2    Kim, K.H.3    Yoon, M.J.4    Cho, H.J.5    Shen, Y.6    Ye, J.-M.7    Lee, C.H.8    Oh, W.K.9    Kim, C.T.10    Hohnen-Behrens, C.11    Gosby, A.12    Kraegen, E.W.13    James, D.E.14    Kim, J.B.15
  • 60
    • 0000959189 scopus 로고
    • Hypoglycemic action of indole-3-acetic acid by mouth in patients with diabetes mellitus
    • 10.3181/00379727-93-22678
    • Diengott D., Mirsky I. A., Hypoglycemic action of indole-3-acetic acid by mouth in patients with diabetes mellitus. Proceedings of the Society for Experimental Biology and Medicine 1956 93 1 109 110 10.3181/00379727-93-22678
    • (1956) Proceedings of the Society for Experimental Biology and Medicine , vol.93 , Issue.1 , pp. 109-110
    • Diengott, D.1    Mirsky, I.A.2
  • 62
    • 80052088740 scopus 로고    scopus 로고
    • Adamantyl ethanone pyridyl derivatives: Potent and selective inhibitors of human 11 β -hydroxysteroid dehydrogenase type 1
    • 2-s2.0-80052088740 10.1002/cmdc.201100182
    • Su X., Pradaux-Caggiano F., Vicker N., Thomas M. P., Halem H., Culler M. D., Potter B. V. L., Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11 β -hydroxysteroid dehydrogenase type 1. ChemMedChem 2011 6 9 1616 1629 2-s2.0-80052088740 10.1002/cmdc.201100182
    • (2011) ChemMedChem , vol.6 , Issue.9 , pp. 1616-1629
    • Su, X.1    Pradaux-Caggiano, F.2    Vicker, N.3    Thomas, M.P.4    Halem, H.5    Culler, M.D.6    Potter, B.V.L.7
  • 64
    • 24044513942 scopus 로고    scopus 로고
    • A review on the role of antioxidants in the management of diabetes and its complications
    • DOI 10.1016/j.biopha.2005.07.002, PII S0753332205001381
    • Rahimi R., Nikfar S., Larijani B., Abdollahi M., A review on the role of antioxidants in the management of diabetes and its complications. Biomedicine and Pharmacotherapy 2005 59 7 365 373 2-s2.0-24044513942 10.1016/j.biopha.2005. 07.002 (Pubitemid 41219650)
    • (2005) Biomedicine and Pharmacotherapy , vol.59 , Issue.7 , pp. 365-373
    • Rahimi, R.1    Nikfar, S.2    Larijani, B.3    Abdollahi, M.4
  • 65
    • 0347301652 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes with a combination regimen of repaglinide plus pioglitazone
    • DOI 10.1016/j.diabres.2003.09.004
    • Jovanovic L., Hassman D. R., Gooch B., Jain R., Greco S., Khutoryansky N., Hale P. M., Treatment of type 2 diabetes with a combination regimen of repaglinide plus pioglitazone. Diabetes Research and Clinical Practice 2004 63 2 127 134 2-s2.0-0347301652 10.1016/j.diabres.2003.09.004 (Pubitemid 38096358)
    • (2004) Diabetes Research and Clinical Practice , vol.63 , Issue.2 , pp. 127-134
    • Jovanovic, L.1    Hassman, D.R.2    Gooch, B.3    Jain, R.4    Greco, S.5    Khutoryansky, N.6    Hale, P.M.7
  • 66
    • 84875768370 scopus 로고    scopus 로고
    • Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients
    • 31543
    • Li R., Ma T., Gu J., Liang X., Li S., Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Scientific Reports 2013 3, article 1543
    • (2013) Scientific Reports
    • Li, R.1    Ma, T.2    Gu, J.3    Liang, X.4    Li, S.5
  • 67
    • 84871737708 scopus 로고    scopus 로고
    • Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome
    • Jiang B., Liang X., Chen Y., Ma T., Liu L., Li J., Jiang R., Chen T., Zhang X., Li S., Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome. Scientific Reports 2012 2, article 936
    • (2012) Scientific Reports , vol.2936
    • Jiang, B.1    Liang, X.2    Chen, Y.3    Ma, T.4    Liu, L.5    Li, J.6    Jiang, R.7    Chen, T.8    Zhang, X.9    Li, S.10
  • 68
    • 84864025055 scopus 로고    scopus 로고
    • Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes
    • 10.1111/j.1464-5491.2012.03655.x
    • Schofield C. J., Sutherland C., Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes. Diabetic Medicine 2012 29 8 972 979 10.1111/j.1464-5491.2012.03655.x
    • (2012) Diabetic Medicine , vol.29 , Issue.8 , pp. 972-979
    • Schofield, C.J.1    Sutherland, C.2
  • 69
    • 0030886025 scopus 로고    scopus 로고
    • Fatty acid-induced insulin resistance in adipocytes
    • DOI 10.1210/en.138.10.4338
    • Van Epps-Fung M., Williford J., Wells A., Hardy R. W., Fatty acid-induced insulin resistance in adipocytes. Endocrinology 1997 138 10 4338 4345 2-s2.0-0030886025 10.1210/en.138.10.4338 (Pubitemid 27408479)
    • (1997) Endocrinology , vol.138 , Issue.10 , pp. 4338-4345
    • Van Epps-Fung, M.1    Williford, J.2    Wells, A.3    Hardy, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.