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Volumn 29, Issue 8, 2012, Pages 972-979

Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes

Author keywords

cell; Insulin resistance; Insulin secretion; Pathogenesis (Type2 diabetes)

Indexed keywords

INSULIN; INSULIN DETEMIR; INSULIN GLARGINE; SULFONYLUREA;

EID: 84864025055     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2012.03655.x     Document Type: Review
Times cited : (69)

References (74)
  • 2
    • 0036314216 scopus 로고    scopus 로고
    • Phasic insulin release and metabolic regulation in type2 diabetes
    • Del Prato S, Marchetti P, Bonadonna RC. Phasic insulin release and metabolic regulation in type2 diabetes. Diabetes 2002; 51: S109-S116.
    • (2002) Diabetes , vol.51
    • Del Prato, S.1    Marchetti, P.2    Bonadonna, R.C.3
  • 3
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden G, Chen X, Ruiz J, White JV, Rossetti L. Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest 1994; 93: 2438-2446.
    • (1994) J Clin Invest , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 4
    • 3543029821 scopus 로고    scopus 로고
    • Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
    • Samuel VT, Liu ZX, Qu X, Elder BD, Bilz S, Befroy D et al. Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem 2004; 279: 32345-32353.
    • (2004) J Biol Chem , vol.279 , pp. 32345-32353
    • Samuel, V.T.1    Liu, Z.X.2    Qu, X.3    Elder, B.D.4    Bilz, S.5    Befroy, D.6
  • 5
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type2 diabetes
    • Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type2 diabetes. Nat Rev Mol Cell Biol 2008; 9: 367-377.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 7
    • 0037073679 scopus 로고    scopus 로고
    • Serine phosphorylation of insulin receptor substrate1 by inhibitor kappa B kinase complex
    • Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ et al. Serine phosphorylation of insulin receptor substrate1 by inhibitor kappa B kinase complex. J Biol Chem 2002; 277: 48115-48121.
    • (2002) J Biol Chem , vol.277 , pp. 48115-48121
    • Gao, Z.1    Hwang, D.2    Bataille, F.3    Lefevre, M.4    York, D.5    Quon, M.J.6
  • 8
    • 84861983219 scopus 로고    scopus 로고
    • Rosiglitazone attenuates tumor necrosis factor-alpha-induced protein tyrosine phosphatase-1B production in HepG2 cells
    • Wu J, Yang LJ, Zou DJ. Rosiglitazone attenuates tumor necrosis factor-alpha-induced protein tyrosine phosphatase-1B production in HepG2 cells. J Endocrinol Invest 2012; 35: 28-34.
    • (2012) J Endocrinol Invest , vol.35 , pp. 28-34
    • Wu, J.1    Yang, L.J.2    Zou, D.J.3
  • 10
    • 0024476904 scopus 로고
    • Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic beta-cells
    • Grapengiesser E, Gylfe E, Hellman B. Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic beta-cells. Arch Biochem Biophys 1989; 268: 404-407.
    • (1989) Arch Biochem Biophys , vol.268 , pp. 404-407
    • Grapengiesser, E.1    Gylfe, E.2    Hellman, B.3
  • 11
    • 0025921541 scopus 로고
    • Propagation of cytoplasmic Ca2+ oscillations in clusters of pancreatic beta-cells exposed to glucose
    • Gylfe E, Grapengiesser E, Hellman B. Propagation of cytoplasmic Ca2+ oscillations in clusters of pancreatic beta-cells exposed to glucose. Cell Calcium 1991; 12: 229-240.
    • (1991) Cell Calcium , vol.12 , pp. 229-240
    • Gylfe, E.1    Grapengiesser, E.2    Hellman, B.3
  • 12
    • 0036314357 scopus 로고    scopus 로고
    • Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism
    • Ainscow EK, Rutter GA. Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism. Diabetes 2002; 51: S162-S170.
    • (2002) Diabetes , vol.51
    • Ainscow, E.K.1    Rutter, G.A.2
  • 13
    • 0023934185 scopus 로고
    • Glucose-induced oscillations of cytoplasmic Ca2+ in the pancreatic beta-cell
    • Grapengiesser E, Gylfe E, Hellman B. Glucose-induced oscillations of cytoplasmic Ca2+ in the pancreatic beta-cell. Biochem Biophys Res Commun 1988; 151: 1299-1304.
    • (1988) Biochem Biophys Res Commun , vol.151 , pp. 1299-1304
    • Grapengiesser, E.1    Gylfe, E.2    Hellman, B.3
  • 14
    • 72449148697 scopus 로고    scopus 로고
    • Pulsatility of insulin release-a clinically important phenomenon
    • Hellman B. Pulsatility of insulin release-a clinically important phenomenon. Ups J Med Sci 2009; 114: 193-205.
    • (2009) Ups J Med Sci , vol.114 , pp. 193-205
    • Hellman, B.1
  • 15
    • 0036360977 scopus 로고    scopus 로고
    • Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ob mice
    • Ravier MA, Sehlin J, Henquin JC. Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ob mice. Diabetologia 2002; 45: 1154-1163.
    • (2002) Diabetologia , vol.45 , pp. 1154-1163
    • Ravier, M.A.1    Sehlin, J.2    Henquin, J.C.3
  • 16
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion-implications for health and disease
    • Ahren B. Autonomic regulation of islet hormone secretion-implications for health and disease. Diabetologia 2000; 43: 393-410.
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahren, B.1
  • 17
    • 71949101801 scopus 로고    scopus 로고
    • Glucose generates coincident insulin and somatostatin pulses and antisynchronous glucagon pulses from human pancreatic islets
    • Hellman B, Salehi A, Gylfe E, Dansk H, Grapengiesser E. Glucose generates coincident insulin and somatostatin pulses and antisynchronous glucagon pulses from human pancreatic islets. Endocrinology 2009; 150: 5334-5340.
    • (2009) Endocrinology , vol.150 , pp. 5334-5340
    • Hellman, B.1    Salehi, A.2    Gylfe, E.3    Dansk, H.4    Grapengiesser, E.5
  • 18
    • 80052824604 scopus 로고    scopus 로고
    • Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type2 diabetes
    • Menge BA, Gruber L, Jorgensen SM, Deacon CF, Schmidt WE, Veldhuis JD et al. Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type2 diabetes. Diabetes 2011; 60: 2160-2168.
    • (2011) Diabetes , vol.60 , pp. 2160-2168
    • Menge, B.A.1    Gruber, L.2    Jorgensen, S.M.3    Deacon, C.F.4    Schmidt, W.E.5    Veldhuis, J.D.6
  • 20
    • 0029746149 scopus 로고    scopus 로고
    • Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass
    • Porksen N, Munn S, Steers J, Veldhuis JD, Butler PC. Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass. Diabetes 1996; 45: 1317-1323.
    • (1996) Diabetes , vol.45 , pp. 1317-1323
    • Porksen, N.1    Munn, S.2    Steers, J.3    Veldhuis, J.D.4    Butler, P.C.5
  • 21
    • 0028814801 scopus 로고
    • Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting
    • Porksen N, Munn S, Steers J, Vore S, Veldhuis J, Butler P. Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting. Am J Physiol 1995; 269: E478-E488.
    • (1995) Am J Physiol , vol.269
    • Porksen, N.1    Munn, S.2    Steers, J.3    Vore, S.4    Veldhuis, J.5    Butler, P.6
  • 24
    • 0029892285 scopus 로고    scopus 로고
    • Association between insulin secretory pulse frequency and peripheral insulin action in NIDDM and normal subjects
    • Hunter SJ, Atkinson AB, Ennis CN, Sheridan B, Bell PM. Association between insulin secretory pulse frequency and peripheral insulin action in NIDDM and normal subjects. Diabetes 1996; 45: 683-686.
    • (1996) Diabetes , vol.45 , pp. 683-686
    • Hunter, S.J.1    Atkinson, A.B.2    Ennis, C.N.3    Sheridan, B.4    Bell, P.M.5
  • 25
    • 12244299450 scopus 로고    scopus 로고
    • Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis
    • Ferrannini E, Gastaldelli A, Miyazaki Y, Matsuda M, Mari A, DeFronzo RA. Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis. J Clin Endocrinol Metab 2005; 90: 493-500.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 493-500
    • Ferrannini, E.1    Gastaldelli, A.2    Miyazaki, Y.3    Matsuda, M.4    Mari, A.5    DeFronzo, R.A.6
  • 26
    • 77954323314 scopus 로고    scopus 로고
    • The stunned beta-cell: a brief history
    • Ferrannini E. The stunned beta-cell: a brief history. Cell Metab 2010; 11: 349-352.
    • (2010) Cell Metab , vol.11 , pp. 349-352
    • Ferrannini, E.1
  • 27
    • 20044368667 scopus 로고    scopus 로고
    • Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans
    • Meier JJ, Veldhuis JD, Butler PC. Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans. Diabetes 2005; 54: 1649-1656.
    • (2005) Diabetes , vol.54 , pp. 1649-1656
    • Meier, J.J.1    Veldhuis, J.D.2    Butler, P.C.3
  • 28
    • 0033826342 scopus 로고    scopus 로고
    • Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type2 diabetes
    • Laedtke T, Kjems L, Porksen N, Schmitz O, Veldhuis J, Kao PC et al. Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type2 diabetes. Am J Physiol Endocrinol Metab 2000; 279: E520-E528.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Laedtke, T.1    Kjems, L.2    Porksen, N.3    Schmitz, O.4    Veldhuis, J.5    Kao, P.C.6
  • 29
    • 56049116225 scopus 로고    scopus 로고
    • Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats
    • Matveyenko AV, Veldhuis JD, Butler PC. Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab 2008; 295: E832-E841.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Matveyenko, A.V.1    Veldhuis, J.D.2    Butler, P.C.3
  • 30
    • 0037021433 scopus 로고    scopus 로고
    • Insulin feedback action on pancreatic beta-cell function
    • Leibiger IB, Leibiger B, Berggren PO. Insulin feedback action on pancreatic beta-cell function. FEBS Lett 2002; 532: 1-6.
    • (2002) FEBS Lett , vol.532 , pp. 1-6
    • Leibiger, I.B.1    Leibiger, B.2    Berggren, P.O.3
  • 31
    • 0036578921 scopus 로고    scopus 로고
    • Beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass
    • Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA et al. Beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. Nat Genet 2002; 31: 111-115.
    • (2002) Nat Genet , vol.31 , pp. 111-115
    • Kulkarni, R.N.1    Holzenberger, M.2    Shih, D.Q.3    Ozcan, U.4    Stoffel, M.5    Magnuson, M.A.6
  • 34
    • 84856537444 scopus 로고    scopus 로고
    • Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans
    • Halperin F, Lopez X, Manning R, Kahn CR, Kulkarni RN, Goldfine AB. Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans. Diabetes 2012; 61: 301-309.
    • (2012) Diabetes , vol.61 , pp. 301-309
    • Halperin, F.1    Lopez, X.2    Manning, R.3    Kahn, C.R.4    Kulkarni, R.N.5    Goldfine, A.B.6
  • 35
    • 84856541164 scopus 로고    scopus 로고
    • Damaging loss of self-control by stressed beta-cells
    • Holness MJ, Sugden MC. Damaging loss of self-control by stressed beta-cells. Diabetes 2012; 61: 267-269.
    • (2012) Diabetes , vol.61 , pp. 267-269
    • Holness, M.J.1    Sugden, M.C.2
  • 36
    • 0024205289 scopus 로고
    • Rapid reduction and return of surface insulin receptors after exposure to brief pulses of insulin in perifused rat hepatocytes
    • Goodner CJ, Sweet IR, Harrison HC Jr. Rapid reduction and return of surface insulin receptors after exposure to brief pulses of insulin in perifused rat hepatocytes. Diabetes 1988; 37: 1316-1323.
    • (1988) Diabetes , vol.37 , pp. 1316-1323
    • Goodner, C.J.1    Sweet, I.R.2    Harrison Jr., H.C.3
  • 37
    • 0018897231 scopus 로고
    • Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level
    • Marshall S, Olefsky JM. Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. J Clin Invest 1980; 66: 763-772.
    • (1980) J Clin Invest , vol.66 , pp. 763-772
    • Marshall, S.1    Olefsky, J.M.2
  • 38
    • 0025060767 scopus 로고
    • Intraportal hyperinsulinemia decreases insulin-stimulated glucose uptake in the dog
    • McGuinness OP, Friedman A, Cherrington AD. Intraportal hyperinsulinemia decreases insulin-stimulated glucose uptake in the dog. Metabolism 1990; 39: 127-132.
    • (1990) Metabolism , vol.39 , pp. 127-132
    • McGuinness, O.P.1    Friedman, A.2    Cherrington, A.D.3
  • 39
    • 0342466624 scopus 로고    scopus 로고
    • Transgenic hyperinsulinemia: a mouse model of insulin resistance and glucose intolerance without obesity
    • Shafrir E, ed. 6th edn. Boston: Birkhauser
    • Marban SL, Roth J. Transgenic hyperinsulinemia: a mouse model of insulin resistance and glucose intolerance without obesity. In: Shafrir E, ed. Lessons from Animal Diabetes VI. 6th edn. Boston: Birkhauser, 1996: 201-224.
    • (1996) Lessons from Animal Diabetes VI , pp. 201-224
    • Marban, S.L.1    Roth, J.2
  • 40
    • 0021361017 scopus 로고
    • Effect of continuous and oscillatory portal vein insulin infusion upon glucose-induced insulin release in rats
    • Stapelfeldt W, Bender H, Schusdziarra V, Pfeiffer EF. Effect of continuous and oscillatory portal vein insulin infusion upon glucose-induced insulin release in rats. Res Exp Med (Berl) 1984; 184: 67-71.
    • (1984) Res Exp Med (Berl) , vol.184 , pp. 67-71
    • Stapelfeldt, W.1    Bender, H.2    Schusdziarra, V.3    Pfeiffer, E.F.4
  • 41
    • 0022497629 scopus 로고
    • Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in typeI diabetic humans
    • Bratusch-Marrain PR, Komjati M, Waldhausl WK. Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in typeI diabetic humans. Diabetes 1986; 35: 922-926.
    • (1986) Diabetes , vol.35 , pp. 922-926
    • Bratusch-Marrain, P.R.1    Komjati, M.2    Waldhausl, W.K.3
  • 42
    • 0022641752 scopus 로고
    • Superior efficacy of pulsatile versus continuous hormone exposure on hepatic glucose production in vitro
    • Komjati M, Bratusch-Marrain P, Waldhausl W. Superior efficacy of pulsatile versus continuous hormone exposure on hepatic glucose production in vitro. Endocrinology 1986; 118: 312-319.
    • (1986) Endocrinology , vol.118 , pp. 312-319
    • Komjati, M.1    Bratusch-Marrain, P.2    Waldhausl, W.3
  • 43
    • 0030884636 scopus 로고    scopus 로고
    • Erratic oscillatory characteristics of plasma insulin concentrations in patients with insulinoma: mechanism for unpredictable hypoglycemia
    • Berman N, Genter P, Chou HF, Cortez C, Bowsher R, Ipp E. Erratic oscillatory characteristics of plasma insulin concentrations in patients with insulinoma: mechanism for unpredictable hypoglycemia. J Clin Endocrinol Metab 1997; 82: 2899-2903.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2899-2903
    • Berman, N.1    Genter, P.2    Chou, H.F.3    Cortez, C.4    Bowsher, R.5    Ipp, E.6
  • 44
    • 0029856092 scopus 로고    scopus 로고
    • Comparison of insulin sensitivity in patients with insulinoma and obese Type2 diabetes mellitus
    • Skrha J, Sindelka G, Haas T, Hilgertova J, Justova V. Comparison of insulin sensitivity in patients with insulinoma and obese Type2 diabetes mellitus. Horm Metab Res 1996; 28: 595-598.
    • (1996) Horm Metab Res , vol.28 , pp. 595-598
    • Skrha, J.1    Sindelka, G.2    Haas, T.3    Hilgertova, J.4    Justova, V.5
  • 45
    • 70349863175 scopus 로고    scopus 로고
    • Beta-cell (dys)function in non-diabetic offspring of diabetic patients
    • Stadler M, Pacini G, Petrie J, Luger A, Anderwald C. Beta-cell (dys)function in non-diabetic offspring of diabetic patients. Diabetologia 2009; 52: 2435-2444.
    • (2009) Diabetologia , vol.52 , pp. 2435-2444
    • Stadler, M.1    Pacini, G.2    Petrie, J.3    Luger, A.4    Anderwald, C.5
  • 46
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • O'Rahilly S, Turner RC, Matthews DR. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 1988; 318: 1225-1230.
    • (1988) N Engl J Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 47
    • 78751575640 scopus 로고    scopus 로고
    • Implications of genome-wide association studies for the understanding of type2 diabetes pathophysiology
    • Petrie JR, Pearson ER, Sutherland C. Implications of genome-wide association studies for the understanding of type2 diabetes pathophysiology. Biochem Pharmacol 2011; 81: 471-477.
    • (2011) Biochem Pharmacol , vol.81 , pp. 471-477
    • Petrie, J.R.1    Pearson, E.R.2    Sutherland, C.3
  • 48
    • 0036772389 scopus 로고    scopus 로고
    • Insights into obesity and insulin resistance from the study of extreme human phenotypes
    • O'Rahilly S. Insights into obesity and insulin resistance from the study of extreme human phenotypes. Eur J Endocrinol 2002; 147: 435-441.
    • (2002) Eur J Endocrinol , vol.147 , pp. 435-441
    • O'Rahilly, S.1
  • 49
    • 70450220107 scopus 로고    scopus 로고
    • Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC
    • Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, Dash S et al. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med 2009; 1: 280-287.
    • (2009) EMBO Mol Med , vol.1 , pp. 280-287
    • Rubio-Cabezas, O.1    Puri, V.2    Murano, I.3    Saudek, V.4    Semple, R.K.5    Dash, S.6
  • 50
    • 67249108808 scopus 로고    scopus 로고
    • A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia
    • Dash S, Sano H, Rochford JJ, Semple RK, Yeo G, Hyden CS et al. A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proc Natl Acad Sci USA 2009; 106: 9350-9355.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9350-9355
    • Dash, S.1    Sano, H.2    Rochford, J.J.3    Semple, R.K.4    Yeo, G.5    Hyden, C.S.6
  • 51
    • 2542528670 scopus 로고    scopus 로고
    • A family with severe insulin resistance and diabetes due to a mutation in AKT2
    • George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC et al. A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 2004; 304: 1325-1328.
    • (2004) Science , vol.304 , pp. 1325-1328
    • George, S.1    Rochford, J.J.2    Wolfrum, C.3    Gray, S.L.4    Schinner, S.5    Wilson, J.C.6
  • 52
    • 0023222361 scopus 로고
    • Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes
    • Caro JF, Sinha MK, Raju SM, Ittoop O, Pories WJ, Flickinger EG et al. Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. J Clin Invest 1987; 79: 1330-1337.
    • (1987) J Clin Invest , vol.79 , pp. 1330-1337
    • Caro, J.F.1    Sinha, M.K.2    Raju, S.M.3    Ittoop, O.4    Pories, W.J.5    Flickinger, E.G.6
  • 53
    • 0346482217 scopus 로고
    • Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture
    • Gavin JR 3rd, Roth J, Neville DM Jr, de Meyts P, Buell DN. Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture. Proc Natl Acad Sci U S A 1974; 71: 84-88.
    • (1974) Proc Natl Acad Sci U S A , vol.71 , pp. 84-88
    • Gavin 3rd, J.R.1    Roth, J.2    Neville Jr., D.M.3    de Meyts, P.4    Buell, D.N.5
  • 54
    • 0017224874 scopus 로고
    • Site-site interactions among insulin receptors. Characterization of the negative cooperativity
    • DeMeyts P, Bainco AR, Roth J. Site-site interactions among insulin receptors. Characterization of the negative cooperativity. J Biol Chem 1976; 251: 1877-1888.
    • (1976) J Biol Chem , vol.251 , pp. 1877-1888
    • DeMeyts, P.1    Bainco, A.R.2    Roth, J.3
  • 55
    • 0024539198 scopus 로고
    • Alternative splicing of human insulin receptor messenger RNA
    • Seino S, Bell GI. Alternative splicing of human insulin receptor messenger RNA. Biochem Biophys Res Commun 1989; 159: 312-316.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 312-316
    • Seino, S.1    Bell, G.I.2
  • 57
    • 0028281921 scopus 로고
    • Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance
    • Kusari J, Kenner KA, Suh KI, Hill DE, Henry RR. Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance. J Clin Invest 1994; 93: 1156-1162.
    • (1994) J Clin Invest , vol.93 , pp. 1156-1162
    • Kusari, J.1    Kenner, K.A.2    Suh, K.I.3    Hill, D.E.4    Henry, R.R.5
  • 58
    • 17044451410 scopus 로고    scopus 로고
    • A new role for SOCS in insulin action. Suppressor of cytokine signaling
    • PE6.
    • Krebs DL, Hilton DJ. A new role for SOCS in insulin action. Suppressor of cytokine signaling. Sci STKE 2003; 2003: PE6.
    • (2003) Sci STKE , vol.2003
    • Krebs, D.L.1    Hilton, D.J.2
  • 59
    • 0037059330 scopus 로고    scopus 로고
    • Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
    • Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 2002; 277: 1531-1537.
    • (2002) J Biol Chem , vol.277 , pp. 1531-1537
    • Aguirre, V.1    Werner, E.D.2    Giraud, J.3    Lee, Y.H.4    Shoelson, S.E.5    White, M.F.6
  • 60
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000; 275: 9047-9054.
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 61
    • 0037474274 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade
    • Lee YH, Giraud J, Davis RJ, White MF. c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade. J Biol Chem 2003; 278: 2896-2902.
    • (2003) J Biol Chem , vol.278 , pp. 2896-2902
    • Lee, Y.H.1    Giraud, J.2    Davis, R.J.3    White, M.F.4
  • 62
    • 1542616960 scopus 로고    scopus 로고
    • Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation
    • Carlson CJ, White MF, Rondinone CM. Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation. Biochem Biophys Res Commun 2004; 316: 533-539.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 533-539
    • Carlson, C.J.1    White, M.F.2    Rondinone, C.M.3
  • 63
    • 3342958797 scopus 로고    scopus 로고
    • The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins
    • Harrington LS, Findlay GM, Gray A, Tolkacheva T, Wigfield S, Rebholz H et al. The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins. J Cell Biol 2004; 166: 213-223.
    • (2004) J Cell Biol , vol.166 , pp. 213-223
    • Harrington, L.S.1    Findlay, G.M.2    Gray, A.3    Tolkacheva, T.4    Wigfield, S.5    Rebholz, H.6
  • 64
    • 0030931560 scopus 로고    scopus 로고
    • Phosphorylation of insulin receptor substrate1 by glycogen synthase kinase3 impairs insulin action
    • Eldar-Finkelman H, Krebs EG. Phosphorylation of insulin receptor substrate1 by glycogen synthase kinase3 impairs insulin action. Proc Natl Acad Sci USA 1997; 94: 9660-9664.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9660-9664
    • Eldar-Finkelman, H.1    Krebs, E.G.2
  • 65
    • 0031465447 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
    • De Fea K, Roth RA. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J Biol Chem 1997; 272: 31400-31406.
    • (1997) J Biol Chem , vol.272 , pp. 31400-31406
    • De Fea, K.1    Roth, R.A.2
  • 66
    • 0029959109 scopus 로고    scopus 로고
    • Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass
    • Porksen NK, Munn SR, Steers JL, Schmitz O, Veldhuis JD, Butler PC. Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass. Diabetes 1996; 45: 1792-1797.
    • (1996) Diabetes , vol.45 , pp. 1792-1797
    • Porksen, N.K.1    Munn, S.R.2    Steers, J.L.3    Schmitz, O.4    Veldhuis, J.D.5    Butler, P.C.6
  • 68
    • 0842333082 scopus 로고    scopus 로고
    • Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort
    • McKeown NM, Meigs JB, Liu S, Saltzman E, Wilson PW, Jacques PF. Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care 2004; 27: 538-546.
    • (2004) Diabetes Care , vol.27 , pp. 538-546
    • McKeown, N.M.1    Meigs, J.B.2    Liu, S.3    Saltzman, E.4    Wilson, P.W.5    Jacques, P.F.6
  • 69
    • 33644827143 scopus 로고    scopus 로고
    • Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sensitivity, secretion, and adiposity in the Insulin Resistance Atherosclerosis Study
    • Liese AD, Schulz M, Fang F, Wolever TM, D'Agostino RB Jr, Sparks KC et al. Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sensitivity, secretion, and adiposity in the Insulin Resistance Atherosclerosis Study. Diabetes Care 2005; 28: 2832-2838.
    • (2005) Diabetes Care , vol.28 , pp. 2832-2838
    • Liese, A.D.1    Schulz, M.2    Fang, F.3    Wolever, T.M.4    D'Agostino Jr., R.B.5    Sparks, K.C.6
  • 70
    • 78651331337 scopus 로고    scopus 로고
    • A low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans
    • Solomon TP, Haus JM, Kelly KR, Cook MD, Filion J, Rocco M et al. A low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans. Am J Clin Nutr 2010; 92: 1359-1368.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1359-1368
    • Solomon, T.P.1    Haus, J.M.2    Kelly, K.R.3    Cook, M.D.4    Filion, J.5    Rocco, M.6
  • 71
    • 12944299291 scopus 로고    scopus 로고
    • Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women
    • McAuley KA, Hopkins CM, Smith KJ, McLay RT, Williams SM, Taylor RW et al. Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women. Diabetologia 2005; 48: 8-16.
    • (2005) Diabetologia , vol.48 , pp. 8-16
    • McAuley, K.A.1    Hopkins, C.M.2    Smith, K.J.3    McLay, R.T.4    Williams, S.M.5    Taylor, R.W.6
  • 72
    • 79955984524 scopus 로고    scopus 로고
    • High-carbohydrate diet selectively induces tumor necrosis factor-alpha production in mice liver
    • Ferreira AV, Mario EG, Porto LC, Andrade SP, Botion LM. High-carbohydrate diet selectively induces tumor necrosis factor-alpha production in mice liver. Inflammation 2011; 34: 139-145.
    • (2011) Inflammation , vol.34 , pp. 139-145
    • Ferreira, A.V.1    Mario, E.G.2    Porto, L.C.3    Andrade, S.P.4    Botion, L.M.5
  • 73
    • 0034072962 scopus 로고    scopus 로고
    • Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells
    • Patane G, Piro S, Rabuazzo AM, Anello M, Vigneri R, Purrello F. Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells. Diabetes 2000; 49: 735-740.
    • (2000) Diabetes , vol.49 , pp. 735-740
    • Patane, G.1    Piro, S.2    Rabuazzo, A.M.3    Anello, M.4    Vigneri, R.5    Purrello, F.6
  • 74
    • 1642414416 scopus 로고    scopus 로고
    • Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARγ2 in the modulation of insulin secretion
    • Lupi R, Del Guerra S, Marselli L, Bugliani M, Boggi U, Mosca F et al. Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARγ2 in the modulation of insulin secretion. Am J Physiol Endocrinol Metab 2004; 286: E560-E567.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Lupi, R.1    Del Guerra, S.2    Marselli, L.3    Bugliani, M.4    Boggi, U.5    Mosca, F.6


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