SCOPUS 정보 검색 플랫폼

Volumn 6, Issue 9, 2011, Pages 1616-1629

Adamantyl ethanone pyridyl derivatives: Potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1

(7) Su, Xiangdong a Pradaux Caggiano, Fabienne a Vicker, Nigel a Thomas, Mark P a Halem, Heather b Culler, Michael D b Potter, Barry V L a

a University of Bath (United Kingdom)

b Biomeasure Inc (United States)

Author keywords

11 HSD1; Adamantyl ethanones; Diabetics; Hydroxysteroid dehydrogenases; Inhibitors; Metabolic syndrome

Indexed keywords

1 (ADAMANTAN 1 YL) 2 (4 METHOXYPYRIDIN 3 YL)METHOXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (6 METHYLPYRIDIN 2 YL)SULFANYL]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (6 METHYLPYRIDINE 2 SULFINYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (6 METHYLPYRIDINE 2 SULFONYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDIN 2 YLSULFANYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDIN 3 YLMETHOXY)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDIN 3 YLOXY)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDIN 4 YLSULFANYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDINE 2 SULFINYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDINE 2 SULFONYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 (PYRIDINE 4 SULFONYL)ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(2 CHLOROPYRIDIN 3 YL)OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(3 METHOXYPYRIDIN 2 YL)METHOXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(5 CHLOROPYRIDIN 3 YL)OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(5 METHOXYPYRIDIN 3 YL)METHOXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(6 CHLOROPYRIDIN 2 YL)OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(6 METHYLPYRIDIN 2 YL)METHOXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(6 METHYLPYRIDIN 2 YL)OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [(6 METHYLPYRIDIN 3 YL)OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [[(5 TRIFLUOROMETHYLPYRIDIN 2 YL)PYRIDIN 2 YL]OXY]ETHAN 1 ONE; 1 (ADAMANTAN 1 YL) 2 [[5 (TRIFLUOROMETHYL)PYRIDIN 2 YL]SULFANYL]ETHAN 1 ONE; 1(ADAMANTAN 1 YL) 2 (PYRIDIN 2 YLMETHOXY)ETHAN 1 ONE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; 6 [[2 (ADAMANTAN 1 YL) 2 OXOETHYL]SULFANYL] N ETHYLPYRIDINE 3 CARBOXAMIDE; 6 [[2 (ADAMANTAN 1 YL) 2 OXOETHYL]SULFANYL] N METHYLPYRIDINE 3 CARBOXAMIDE; 6 [[2 (ADAMANTAN 1 YL) 2 OXOETHYL]SULFANYL] N,N DIMETHYLPYRIDINE 3 CARBOXAMIDE; 6 [[2 (ADAMANTAN 1 YL) 2 OXOETHYL]SULFANYL]PYRIDINE 3 CARBOXAMIDE; 6 [[2 (ADAMANTAN 1 YL) 2 OXOETHYL]SULFANYL]PYRIDINE 3 CARBOXYLIC ACID; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LIVER MICROSOME; MOLECULAR DOCKING; MOUSE; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; STRUCTURE ACTIVITY RELATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADAMANTANE; ANIMALS; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; HEK293 CELLS; HUMANS; HYDROXYSTEROID DEHYDROGENASES; KIDNEY; METABOLIC DISEASES; MICE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80052088740 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100182 Document Type: Article

Times cited : (13)

References (47)

1
- 1842842014
- S. M. Grundy, H. B. Brewer, Jr., J. I. Cleeman, S. C. Smith, Jr., C. Lenfant, Arterioscler. Thromb. Vasc. Biol. 2004, 24, e13-18.
- (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24
- Grundy, S.M.¹ Brewer Jr., H.B.² Cleeman, J.I.³ Smith Jr., S.C.⁴ Lenfant, C.⁵

2
- 30944451953
- P. W. Wilson, R. B. D'Agostino, H. Parise, L. Sullivan, J. B. Meigs, Circulation 2005, 112, 3066-3072.
- (2005) Circulation , vol.112 , pp. 3066-3072
- Wilson, P.W.¹ D'Agostino, R.B.² Parise, H.³ Sullivan, L.⁴ Meigs, J.B.⁵

3
- 0035656177
- T. C. Sandeep, B. R. Walker, Trends Endocrinol. Metab. 2001, 12, 446-453.
- (2001) Trends Endocrinol. Metab. , vol.12 , pp. 446-453
- Sandeep, T.C.¹ Walker, B.R.²

4
- 4043077286
- J. W. Tomlinson, E. A. Walker, I. J. Bujalska, N. Draper, G. G. Lavery, M. S. Cooper, M. Hewison, P. M. Stewart, Endocr. Rev. 2004, 25, 831-866.
- (2004) Endocr. Rev. , vol.25 , pp. 831-866
- Tomlinson, J.W.¹ Walker, E.A.² Bujalska, I.J.³ Draper, N.⁴ Lavery, G.G.⁵ Cooper, M.S.⁶ Hewison, M.⁷ Stewart, P.M.⁸

5
- 34447099301
- K. E. Chapman, A. Coutinho, M. Gray, J. S. Gilmour, J. S. Savill, J. R. Seckl, Ann. N. Y. Acad. Sci. 2006, 1088, 265-273.
- (2006) Ann. N. Y. Acad. Sci. , vol.1088 , pp. 265-273
- Chapman, K.E.¹ Coutinho, A.² Gray, M.³ Gilmour, J.S.⁴ Savill, J.S.⁵ Seckl, J.R.⁶

6
- 33751215200
- B. R. Walker, Diabetic Med. 2006, 23, 1281-1288.
- (2006) Diabetic Med. , vol.23 , pp. 1281-1288
- Walker, B.R.¹

7
- 26844573524
- R. Thieringer, A. Hermanowski-Vosatka, Expert Rev. Cardiovasc. Ther. 2005, 3, 911-924.
- (2005) Expert Rev. Cardiovasc. Ther. , vol.3 , pp. 911-924
- Thieringer, R.¹ Hermanowski-Vosatka, A.²

8
- 0034454682
- R. M. Sapolsky, L. M. Romero, A. U. Munck, Endocr. Rev. 2000, 21, 55-89.
- (2000) Endocr. Rev. , vol.21 , pp. 55-89
- Sapolsky, R.M.¹ Romero, L.M.² Munck, A.U.³

9
- 0027288233
- J. E. Friedman, J. S. Yun, Y. M. Patel, M. M. McGrane, R. W. Hanson, J. Biol. Chem. 1993, 268, 12952-12957.
- (1993) J. Biol. Chem. , vol.268 , pp. 12952-12957
- Friedman, J.E.¹ Yun, J.S.² Patel, Y.M.³ McGrane, M.M.⁴ Hanson, R.W.⁵

10
- 27144509346
- M. Wang, Nutr. Metab. 2005, 2, 3.
- (2005) Nutr. Metab. , vol.2 , pp. 3
- Wang, M.¹

11
- 0033127892
- P. O. Hasselgren, Curr. Opin. Clin. Nutr. Metab. Care 1999, 2, 201-205.
- (1999) Curr. Opin. Clin. Nutr. Metab. Care , vol.2 , pp. 201-205
- Hasselgren, P.O.¹

12
- 34447105433
- M. Wamil, J. R. Seckl, Drug Discovery Today 2007, 12, 504-520.
- (2007) Drug Discovery Today , vol.12 , pp. 504-520
- Wamil, M.¹ Seckl, J.R.²

13
- 9144250366
- G. Arnaldi, A. Angeli, A. B. Atkinson, X. Bertagna, F. Cavagnini, G. P. Chrousos, G. A. Fava, J. W. Findling, R. C. Gaillard, A. B. Grossman, B. Kola, A. Lacroix, T. Mancini, F. Mantero, J. Newell-Price, L. K. Nieman, N. Sonino, M. L. Vance, A. Giustina, M. Boscaro, J. Clin. Endocrinol. Metab. 2003, 88, 5593-5602.
- (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 5593-5602
- Arnaldi, G.¹ Angeli, A.² Atkinson, A.B.³ Bertagna, X.⁴ Cavagnini, F.⁵ Chrousos, G.P.⁶ Fava, G.A.⁷ Findling, J.W.⁸ Gaillard, R.C.⁹ Grossman, A.B.¹⁰ Kola, B.¹¹ Lacroix, A.¹² Mancini, T.¹³ Mantero, F.¹⁴ Newell-Price, J.¹⁵ Nieman, L.K.¹⁶ Sonino, N.¹⁷ Vance, M.L.¹⁸ Giustina, A.¹⁹ Boscaro, M.²⁰ more..

14
- 0036095881
- B. S. McEwen, J. Clin. Endocrinol. Metab. 2002, 87, 1947-1948.
- (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1947-1948
- McEwen, B.S.¹

15
- 0038305844
- A. Faggiano, R. Pivonello, S. Spiezia, M. C. DeMartino, M. Filippella, C. DiSomma, G. Lombardi, A. Colao, J. Clin. Endocrinol. Metab. 2003, 88, 2527-2533.
- (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2527-2533
- Faggiano, A.¹ Pivonello, R.² Spiezia, S.³ DeMartino, M.C.⁴ Filippella, M.⁵ DiSomma, C.⁶ Lombardi, G.⁷ Colao, A.⁸

16
- 0034880195
- J. W. Chu, D. F. Matthias, J. Belanoff, A. Schatzberg, A. R. Hoffman, D. Feldman, J. Clin. Endocrinol. Metab. 2001, 86, 3568-3573.
- (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 3568-3573
- Chu, J.W.¹ Matthias, D.F.² Belanoff, J.³ Schatzberg, A.⁴ Hoffman, A.R.⁵ Feldman, D.⁶

17
- 0033018598
- R. Fraser, M. C. Ingram, N. H. Anderson, C. Morrison, E. Davies, J. M. C. Connell, Hypertension 1999, 33, 1364-1368.
- (1999) Hypertension , vol.33 , pp. 1364-1368
- Fraser, R.¹ Ingram, M.C.² Anderson, N.H.³ Morrison, C.⁴ Davies, E.⁵ Connell, J.M.C.⁶

18
- 85047683614
- J. R. Seckl, B. R. Walker, Endocrinology 2001, 142, 1371-1376.
- (2001) Endocrinology , vol.142 , pp. 1371-1376
- Seckl, J.R.¹ Walker, B.R.²

19
- 0028785017
- R. C. Wilson, M. D. Harbison, Z. S. Krozowski, J. W. Funder, C. H. Shackleton, H. M. Hanauske-Abel, J. Q. Wei, J. Hertecant, A. Moran, R. E. Neiberger, etal., J. Clin. Endocrinol. Metab. 1995, 80, 3145-3150.
- (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3145-3150
- Wilson, R.C.¹ Harbison, M.D.² Krozowski, Z.S.³ Funder, J.W.⁴ Shackleton, C.H.⁵ Hanauske-Abel, H.M.⁶ Wei, J.Q.⁷ Hertecant, J.⁸ Moran, A.⁹ Neiberger, R.E.¹⁰

20
- 0023242981
- P. M. Stewart, A. M. Wallace, R. Valentino, D. Burt, C. H. L. Shackleton, C. R. W. Edwards, Lancet 1987, 330, 821-824.
- (1987) Lancet , vol.330 , pp. 821-824
- Stewart, P.M.¹ Wallace, A.M.² Valentino, R.³ Burt, D.⁴ Shackleton, C.H.L.⁵ Edwards, C.R.W.⁶

21
- 0028081325
- A. K. Agarwal, T. Mune, C. Monder, P. C. White, J. Biol. Chem. 1994, 269, 25959-25962.
- (1994) J. Biol. Chem. , vol.269 , pp. 25959-25962
- Agarwal, A.K.¹ Mune, T.² Monder, C.³ White, P.C.⁴

22
- 0035824440
- H. Masuzaki, J. Paterson, H. Shinyama, N. M. Morton, J. J. Mullins, J. R. Seckl, J. S. Flier, Science 2001, 294, 2166-2170.
- (2001) Science , vol.294 , pp. 2166-2170
- Masuzaki, H.¹ Paterson, J.² Shinyama, H.³ Morton, N.M.⁴ Mullins, J.J.⁵ Seckl, J.R.⁶ Flier, J.S.⁷

23
- 85047693986
- H. Masuzaki, H. Yamamoto, C. J. Kenyon, J. K. Elmquist, N. M. Morton, J. M. Paterson, H. Shinyama, M. G. Sharp, S. Fleming, J. J. Mullins, J. R. Seckl, J. S. Flier, J. Clin. Invest. 2003, 112, 83-90.
- (2003) J. Clin. Invest. , vol.112 , pp. 83-90
- Masuzaki, H.¹ Yamamoto, H.² Kenyon, C.J.³ Elmquist, J.K.⁴ Morton, N.M.⁵ Paterson, J.M.⁶ Shinyama, H.⁷ Sharp, M.G.⁸ Fleming, S.⁹ Mullins, J.J.¹⁰ Seckl, J.R.¹¹ Flier, J.S.¹²

24
- 0031283178
- Y. Kotelevtsev, M. C. Holmes, A. Burchell, P. M. Houston, D. Schmoll, P. Jamieson, R. Best, R. Brown, C. R. W. Edwards, J. R. Seckl, J. J. Mullins, Proc. Natl. Acad. Sci. USA 1997, 94, 14924-14929.
- (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14924-14929
- Kotelevtsev, Y.¹ Holmes, M.C.² Burchell, A.³ Houston, P.M.⁴ Schmoll, D.⁵ Jamieson, P.⁶ Best, R.⁷ Brown, R.⁸ Edwards, C.R.W.⁹ Seckl, J.R.¹⁰ Mullins, J.J.¹¹

25
- 12144291638
- N. M. Morton, J. M. Paterson, H. Masuzaki, M. C. Holmes, B. Staels, C. Fievet, B. R. Walker, J. S. Flier, J. J. Mullins, J. R. Seckl, Diabetes 2004, 53, 931-938.
- (2004) Diabetes , vol.53 , pp. 931-938
- Morton, N.M.¹ Paterson, J.M.² Masuzaki, H.³ Holmes, M.C.⁴ Staels, B.⁵ Fievet, C.⁶ Walker, B.R.⁷ Flier, J.S.⁸ Mullins, J.J.⁹ Seckl, J.R.¹⁰

26
- 15944394711
- E. E. Kershaw, N. M. Morton, H. Dhillon, L. Ramage, J. R. Seckl, J. S. Flier, Diabetes 2005, 54, 1023-1031.
- (2005) Diabetes , vol.54 , pp. 1023-1031
- Kershaw, E.E.¹ Morton, N.M.² Dhillon, H.³ Ramage, L.⁴ Seckl, J.R.⁵ Flier, J.S.⁶

27
- 0036432995
- P. Alberts, L. Engblom, N. Edling, M. Forsgren, G. Klingstrom, C. Larsson, Y. Ronquist-Nii, B. Ohman, L. Abrahmsen, Diabetologia 2002, 45, 1528-1532.
- (2002) Diabetologia , vol.45 , pp. 1528-1532
- Alberts, P.¹ Engblom, L.² Edling, N.³ Forsgren, M.⁴ Klingstrom, G.⁵ Larsson, C.⁶ Ronquist-Nii, Y.⁷ Ohman, B.⁸ Abrahmsen, L.⁹

28
- 0242468543
- P. Alberts, C. Nilsson, G. Selen, L. O. M. Engblom, N. H. M. Edling, S. Norling, G. Klingstrom, C. Larsson, M. Forsgren, M. Ashkzari, C. E. Nilsson, M. Fiedler, E. Bergqvist, B. Ohman, E. Bjorkstrand, L. B. Abrahmsen, Endocrinology 2003, 144, 4755-4762.
- (2003) Endocrinology , vol.144 , pp. 4755-4762
- Alberts, P.¹ Nilsson, C.² Selen, G.³ Engblom, L.O.M.⁴ Edling, N.H.M.⁵ Norling, S.⁶ Klingstrom, G.⁷ Larsson, C.⁸ Forsgren, M.⁹ Ashkzari, M.¹⁰ Nilsson, C.E.¹¹ Fiedler, M.¹² Bergqvist, E.¹³ Ohman, B.¹⁴ Bjorkstrand, E.¹⁵ Abrahmsen, L.B.¹⁶

29
- 23944493717
- A. Hermanowski-Vosatka, J. M. Balkovec, K. Cheng, H. Y. Chen, M. Hernandez, G. C. Koo, C. B. LeGrand, Z. H. Li, J. M. Metzger, S. S. Mundt, H. Noonan, C. N. Nunes, S. H. Olson, B. Pikounis, N. Ren, N. Robertson, J. M. Schaeffer, K. Shah, M. S. Springer, A. M. Strack, M. Strowski, K. Wu, T. J. Wu, J. Y. Xiao, B. B. Zhang, S. D. Wright, R. Thieringer, J. Exp. Med. 2005, 202, 517-527.
- (2005) J. Exp. Med. , vol.202 , pp. 517-527
- Hermanowski-Vosatka, A.¹ Balkovec, J.M.² Cheng, K.³ Chen, H.Y.⁴ Hernandez, M.⁵ Koo, G.C.⁶ LeGrand, C.B.⁷ Li, Z.H.⁸ Metzger, J.M.⁹ Mundt, S.S.¹⁰ Noonan, H.¹¹ Nunes, C.N.¹² Olson, S.H.¹³ Pikounis, B.¹⁴ Ren, N.¹⁵ Robertson, N.¹⁶ Schaeffer, J.M.¹⁷ Shah, K.¹⁸ Springer, M.S.¹⁹ Strack, A.M.²⁰ more..

30
- 0028839840
- B. R. Walker, A. A. Connacher, R. M. Lindsay, D. J. Webb, C. R. W. Edwards, J. Clin. Endocrinol. Metab. 1995, 80, 3155-3159.
- (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3155-3159
- Walker, B.R.¹ Connacher, A.A.² Lindsay, R.M.³ Webb, D.J.⁴ Edwards, C.R.W.⁵

31
- 0037238379
- R. C. Andrews, O. Rooyackers, B. R. Walker, J. Clin. Endocrinol. Metab. 2003, 88, 285-291.
- (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 285-291
- Andrews, R.C.¹ Rooyackers, O.² Walker, B.R.³

32
- 41149085727
- X. Su, N. Vicker, B. V. L. Potter, Prog. Med. Chem. 2008, 46, 29-130.
- (2008) Prog. Med. Chem. , vol.46 , pp. 29-130
- Su, X.¹ Vicker, N.² Potter, B.V.L.³

33
- 40049094652
- C. G. Schnackenberg, Curr. Opin. Invest. Drugs 2008, 9, 295-300.
- (2008) Curr. Opin. Invest. Drugs , vol.9 , pp. 295-300
- Schnackenberg, C.G.¹

34
- 42149162795
- K. A. Hughes, S. P. Webster, B. R. Walker, Expert Opin. Invest. Drugs 2008, 17, 481-496.
- (2008) Expert Opin. Invest. Drugs , vol.17 , pp. 481-496
- Hughes, K.A.¹ Webster, S.P.² Walker, B.R.³

35
- 50249091534
- C. Fotsch, M. H. Wang, J. Med. Chem. 2008, 51, 4851-4857.
- (2008) J. Med. Chem. , vol.51 , pp. 4851-4857
- Fotsch, C.¹ Wang, M.H.²

36
- 67649362287
- C. D. Boyle, T. J. Kowalski, Expert Opin. Ther. Pat. 2009, 19, 801-825.
- (2009) Expert Opin. Ther. Pat. , vol.19 , pp. 801-825
- Boyle, C.D.¹ Kowalski, T.J.²

37
- 77950664531
- R. Ge, Y. Huang, G. Liang, X. Li, Curr. Med. Chem. 2010, 17, 412-422.
- (2010) Curr. Med. Chem. , vol.17 , pp. 412-422
- Ge, R.¹ Huang, Y.² Liang, G.³ Li, X.⁴

38
- 39049131253
- R. Courtney, P. M. Stewart, M. Toh, M. N. Ndongo, R. A. Calle, B. Hirshberg, J. Clin. Endocrinol. Metab. 2008, 93, 550-556.
- (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 550-556
- Courtney, R.¹ Stewart, P.M.² Toh, M.³ Ndongo, M.N.⁴ Calle, R.A.⁵ Hirshberg, B.⁶

39
- 64549162134
- 57 (Suppl.1), A-A.
- M. Hawkins, D. Hunter, P. Kishore, S. Schwartz, M. Hompesch, G. Hollis, R. Levy, B. Williams, R. Huber, Diabetes 2008, 57 (Suppl.1), A99-A100.
- (2008) Diabetes , pp. 99-100
- Hawkins, M.¹ Hunter, D.² Kishore, P.³ Schwartz, S.⁴ Hompesch, M.⁵ Hollis, G.⁶ Levy, R.⁷ Williams, B.⁸ Huber, R.⁹

40
- 77955630861
- J. Rosenstock, S. Banarer, V. A. Fonseca, S. E. Inzucchi, W. Sun, W. Yao, G. Hollis, R. Flores, R. Levy, W. V. Williams, J. R. Seckl, R. Huber, Diabetes Care 2010, 33, 1516-1522.
- (2010) Diabetes Care , vol.33 , pp. 1516-1522
- Rosenstock, J.¹ Banarer, S.² Fonseca, V.A.³ Inzucchi, S.E.⁴ Sun, W.⁵ Yao, W.⁶ Hollis, G.⁷ Flores, R.⁸ Levy, R.⁹ Williams, W.V.¹⁰ Seckl, J.R.¹¹ Huber, R.¹²

41
- 77954141448
- X. Su, F. Pradaux-Caggiano, M. P. Thomas, M. W. Szeto, H. A. Halem, M. D. Culler, N. Vicker, B. V. L. Potter, ChemMedChem 2010, 5, 1026-1044.
- (2010) ChemMedChem , vol.5 , pp. 1026-1044
- Su, X.¹ Pradaux-Caggiano, F.² Thomas, M.P.³ Szeto, M.W.⁴ Halem, H.A.⁵ Culler, M.D.⁶ Vicker, N.⁷ Potter, B.V.L.⁸

42
- 79960688526
- ChemMedChem, in press; DOI:
- X. Su, N. Vicker, M.P. Thomas, F. Pradaux-Caggiano, H.A. Halem, M.D. Culler, B.V.L. Potter, ChemMedChem, 2011, in press; DOI:.
- (2001)
- Su, X.¹ Vicker, N.² Thomas, M.P.³ Pradaux-Caggiano, F.⁴ Halem, H.A.⁵ Culler, M.D.⁶ Potter, B.V.L.⁷

43
- 79953235168
- M. P. Thomas, B. V. L. Potter, Future Med. Chem. 2011, 3, 367-390.
- (2011) Future Med. Chem. , vol.3 , pp. 367-390
- Thomas, M.P.¹ Potter, B.V.L.²

44
- 0032733974
- R. S. Obach, Drug Metab. Dispos. 1999, 27, 1350-1359.
- (1999) Drug Metab. Dispos. , vol.27 , pp. 1350-1359
- Obach, R.S.¹

45
- 33846165085
- B. Sorensen, M. Winn, J. Rohde, Q. Shuai, J. Wang, S. Fung, K. Monzon, W. Chiou, D. Stolarik, H. Imade, L. Pan, X. Deng, L. Chovan, K. Longenecker, R. Judge, W. Qin, M. Brune, H. Camp, E. U. Frevert, P. Jacobson, J. T. Link, Bioorg. Med. Chem. Lett. 2007, 17, 527-532.
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 527-532
- Sorensen, B.¹ Winn, M.² Rohde, J.³ Shuai, Q.⁴ Wang, J.⁵ Fung, S.⁶ Monzon, K.⁷ Chiou, W.⁸ Stolarik, D.⁹ Imade, H.¹⁰ Pan, L.¹¹ Deng, X.¹² Chovan, L.¹³ Longenecker, K.¹⁴ Judge, R.¹⁵ Qin, W.¹⁶ Brune, M.¹⁷ Camp, H.¹⁸ Frevert, E.U.¹⁹ Jacobson, P.²⁰ Link, J.T.²¹ more..

46
- 80052095845
- Sterix Limited, UK), PCT application: WO/2006/100502
- N. Vicker, X. Su, F. Pradaux, M. J. Reed, B. V. L. Potter, (Sterix Limited, UK), PCT application: WO/2006/100502, 2006.
- (2006)
- Vicker, N.¹ Su, X.² Pradaux, F.³ Reed, M.J.⁴ Potter, B.V.L.⁵

47
- 0033214482
- A. Odermatt, P. Arnold, A. Stauffer, B. M. Frey, F. J. Frey, J. Biol. Chem. 1999, 274, 28762-28770.
- (1999) J. Biol. Chem. , vol.274 , pp. 28762-28770
- Odermatt, A.¹ Arnold, P.² Stauffer, A.³ Frey, B.M.⁴ Frey, F.J.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.