Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy

Transplantation

Volumn 84, Issue 9, 2007, Pages 1183-1190

  Chien, Chiang Ting ^a   Shyue, Song Kuen ^b   Lai, Ming Kuen ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Adenoviral bcl xL; Apoptosis; Autophagy; Ischemia reperfusion; Reactive oxygen species

Indexed keywords

ADENOVIRUS VECTOR; BECLIN 1; CASPASE 3; CYTOCHROME C; MICROTUBULE ASSOCIATED PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYGEN; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE TRANSFER; GLOMERULUS; KIDNEY DISTAL TUBULE; KIDNEY DYSFUNCTION; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REPERFUSION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; FEMALE; GENE TRANSFER TECHNIQUES; HUMANS; ISCHEMIA; KIDNEY TUBULES, DISTAL; KIDNEY TUBULES, PROXIMAL; PROMOTER REGIONS (GENETICS); RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 36249011527     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000287334.38933.e3     Document Type: Article

References (37)

1. Bilzer M, Paumgartner G, Gerbes AL. Glutathione protects the rat liver against reperfusion injury after hypothermic preservation. Gastroenterology 1999; 117: 200.
2. Chien CT, Lee PH, Chen CF, et al. De novo demonstration and colocalization of free-radical production and apoptosis formation in rat kidney subjected to ischemia/reperfusion. J Am Soc Nephrol 2001; 12: 973.
3. Plesnila N, Zhu C, Culmsee C, et al. Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J Cereb Blood Flow Metab 2004; 24: 458.
4. Rajesh KG, Sasaguri S, Suzuki R, Maeda H. Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression. Am J Physiol Heart Circ Physiol 2003; 285: H2171.
5. Hunter T. Protein kinase and phosphatase: The yin and yang of protein phosphorylation and signaling. Cell 1995; 80: 225.
6. Stamler JS. Redox signaling: Nitrosylation and related target interactions of nitric oxide. Cell 1994; 78: 931.
7. Salahudeen AK, Huang H, Joshi M, et al. Involvement of the mitochondrial pathway in cold storage and rewarming-associated apoptosis of human renal proximal tubular cells. Am J Transplant 2003; 3: 273.
8. Scherz-Shouval R, Shvets E, Fass E, et al. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007; 26: 1749.
9. Vande Velde C, Cizeau J, Dubik D, et al. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 2000; 20: 5454.
10. Chien CT, Chang TC, Tsai CY, et al. Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis. Am J Transplant 2005; 5: 1194.
11. Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479.
12. Antonsson B, Montessuit S, Lauper S, et al. Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria. Biochem J 2000; 345: 271.
13. Gross A, Jockel J, Wei MC, Korsmeyer SJ. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J 1998; 17: 3878.
14. Adams JM, Cory S. The Bcl-2 protein family: Arbiters of cell survival. Science 1998; 281: 1322.
15. Blanco-Colio LM, Justo P, Daehn I, et al. Bcl-xL overexpression protects from apoptosis induced by HMG-CoA reductase inhibitors in murine tubular cells. Kidney Int 2003; 64: 181.
16. Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit beclin-1 dependent autophagy. Cell 2005; 122: 927.
17. Zhu C, Wang X, Xu F, et al. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differentiation 2005; 12: 162.
18. Basile DP, Liapis H, Hammerman MR. Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am J Physiol 1997; 272: F640.
19. Kaushal GP, Singh AB, Shah SV. Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury. Am J Physiol 1998; 274: F587.
20. McGown AJ, Ruiz-Ruiz MC, Gorman AM, et al. Reactive oxygen intermediate(s) (ROI): Common mediator(s) of poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis. FEBS Lett 1996; 39: 299.
21. Perskvist N, Long M, Stendahl O, Zheng L. Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway. J Immunol 2002; 168: 6358.
22. Cuttle L, Zhang XJ, Endre ZH, et al. Bcl-xL translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress. Kidney Int 2001; 59: 1779.
23. Hildeman DA, Mitchell T, Aronow B, et al. Control of Bcl-2 expression by reactive oxygen species. Proc Natl Acad Sci USA 2003; 100: 15035.
24. Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999; 399: 483.
25. Reed JC. Double identity for proteins of the Bcl-2 family. Nature 1997; 387: 773.
26. Shyue SK, Tsai MJ, Liou JY, et al. Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. Circulation 2001; 103: 2090.
27. Su YT, Chang HL, Shyue SK, Hsu SL. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen speciesdependent mitochondrial signaling pathway. Biochem Pharmacol 2005; 70: 229.
28. Digerness SB, Harris KD, Kirklin JW, et al. Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle. Free Radic Biol Med 1999; 27: 1386.
29. Kono H, Arteel GE, Rusyn I, et al. Ebselen prevents early alcohol-induced liver injury in rats. Free Radic Biol Med 2001; 30: 403.
30. Kruger AL, Peterson SJ, Schwartzman ML, et al. Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects. J Pharmacol Exp Ther 2006; 319: 1144.
31. Richter C, Schweizer M, Cossarizza, Franceschi C. Control of apoptosis by the cellular ATP level. FEBS Lett 1996; 378: 107.
32. Petronilli V, Costantini P, Scorrano L, et al. The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols: Increase of the gating potential by oxidants and its reversal by reducing agents. J Biol Chem 1994; 269: 16638.
33. Lemasters JJ, Qian T, He L, et al. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid Redox Signa 2002; 4: 769.
34. Madesh M, Hajnoczky G. VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J Cell Biol 2001; 155: 1003.
35. Stefanis L. Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist 2005; 11: 50.
36. Yanagisawa H, Miyashita T, Nakano Y, Yamamoto D. HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. Cell Death Differ 2003; 10: 798.
37. Chen QM, Alexander D, Sun H, et al. Corticosteroids inhibit cell death induced by doxorubicin in cardiomyocytes: Induction of antiapoptosis, antioxidant, and detoxification genes. Mol Pharmacol 2005; 67: 1861.