PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

Nature Medicine

Volumn 18, Issue 1, 2012, Pages 100-110

  Xue, Yuan ^a   Lim, Sharon ^a   Yang, Yunlong ^a   Wang, Zongwei ^a   Jensen, Lasse Dahl Ejby ^a   Hedlund, Eva Maria ^a   Andersson, Patrik ^a   Sasahara, Masakiyo ^b   Larsson, Ola ^a   Galter, Dagmar ^a   Cao, Renhai ^a   Hosaka, Kayoko ^a   Cao, Yihai ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF TOYAMA   (Japan)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ADENOVIRUS VECTOR; ERYTHROPOIETIN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN C JUN; TRANSCRIPTION FACTOR SP1;

ANEMIA; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL EXPANSION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRAMEDULLARY HEMATOPOIESIS; FEMALE; HEMATOPOIESIS; IMMUNOHISTOCHEMISTRY; IRRADIATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STROMA CELL; TRANSCRIPTION REGULATION; TUMOR GROWTH;

ANEMIA; ANIMALS; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ERYTHROPOIETIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEMATOPOIESIS; MICE; MICE, INBRED C57BL; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; PROTO-ONCOGENE PROTEINS C-SIS; SIGNAL TRANSDUCTION; STROMAL CELLS;

MUS;

EID: 84855545329     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2575     Document Type: Article

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