-
1
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10-30.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
-
2
-
-
0034085989
-
Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
-
Bubendorf L, Schopfer A, Wagner U, et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol. 2000;31:578-583.
-
(2000)
Hum Pathol
, vol.31
, pp. 578-583
-
-
Bubendorf, L.1
Schopfer, A.2
Wagner, U.3
-
3
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 1998;93:165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
-
4
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
Kong YY, Feige U, Sarosi I, et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature. 1999;402:304-309.
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
-
5
-
-
0032545355
-
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis
-
Nakagawa N, Kinosaki M, Yamaguchi K, et al. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res Commun. 1998;253:395-400.
-
(1998)
Biochem Biophys Res Commun
, vol.253
, pp. 395-400
-
-
Nakagawa, N.1
Kinosaki, M.2
Yamaguchi, K.3
-
6
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 1997;89:309-319.
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
-
7
-
-
0032079445
-
Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
-
Bucay N, Sarosi I, Dunstan CR, et al. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev. 1998;12:1260-1268.
-
(1998)
Genes Dev
, vol.12
, pp. 1260-1268
-
-
Bucay, N.1
Sarosi, I.2
Dunstan, C.R.3
-
8
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
Dougall WC, Glaccum M, Charrier K, et al. RANK is essential for osteoclast and lymph node development. Genes Dev. 1999;13:2412-2424.
-
(1999)
Genes Dev
, vol.13
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
-
9
-
-
0032577903
-
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
-
Mizuno A, Amizuka N, We K, et al. Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun. 1998;247:610-615.
-
(1998)
Biochem Biophys Res Commun
, vol.247
, pp. 610-615
-
-
Mizuno, A.1
Amizuka, N.2
We, K.3
-
10
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2:584-593.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
11
-
-
11344261227
-
Expression of receptor activator of nuclear factor-kappaB is inversely correlated with metastatic phenotype in breast carcinoma
-
Bhatia P, Sanders MM, Hansen MF. Expression of receptor activator of nuclear factor-kappaB is inversely correlated with metastatic phenotype in breast carcinoma. Clin Cancer Res. 2005;11:162-165.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 162-165
-
-
Bhatia, P.1
Sanders, M.M.2
Hansen, M.F.3
-
12
-
-
0141482103
-
Receptor activator of nuclear factor-kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo
-
Farrugia AN, Atkins GJ, To LB, et al. Receptor activator of nuclear factor-kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo. Cancer Res. 2003;63:5438-5445.
-
(2003)
Cancer Res
, vol.63
, pp. 5438-5445
-
-
Farrugia, A.N.1
Atkins, G.J.2
To, L.B.3
-
13
-
-
0033873632
-
Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: Possible involvement in tumor cell-induced osteoclast-like cell formation
-
Huang L, Xu J, Wood DJ, Zheng MH. Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am J Pathol. 2000;156:761-767.
-
(2000)
Am J Pathol
, vol.156
, pp. 761-767
-
-
Huang, L.1
Xu, J.2
Wood, D.J.3
Zheng, M.H.4
-
14
-
-
0037395314
-
Receptor activator of NF-kappaB ligand (RANKL) is expressed in chondroblastoma: Possible involvement in osteoclastic giant cell recruitment
-
Huang L, Cheng YY, Chow LT, Zheng MH, Kumta SM. Receptor activator of NF-kappaB ligand (RANKL) is expressed in chondroblastoma: possible involvement in osteoclastic giant cell recruitment. Mol Pathol. 2003;56:116-120.
-
(2003)
Mol Pathol
, vol.56
, pp. 116-120
-
-
Huang, L.1
Cheng, Y.Y.2
Chow, L.T.3
Zheng, M.H.4
Kumta, S.M.5
-
15
-
-
4143057125
-
In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells
-
Granchi D, Amato I, Battistelli L, et al. In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells. Int J Cancer. 2004;111:829-838.
-
(2004)
Int J Cancer
, vol.111
, pp. 829-838
-
-
Granchi, D.1
Amato, I.2
Battistelli, L.3
-
16
-
-
22044436505
-
Oral squamous cell carcinoma cells induce osteoclast differentiation by suppression of osteoprotegerin expression in osteoblasts
-
Tada T, Jimi E, Okamoto M, Ozeki S, Okabe K. Oral squamous cell carcinoma cells induce osteoclast differentiation by suppression of osteoprotegerin expression in osteoblasts. Int J Cancer. 2005;116:253-262.
-
(2005)
Int J Cancer
, vol.116
, pp. 253-262
-
-
Tada, T.1
Jimi, E.2
Okamoto, M.3
Ozeki, S.4
Okabe, K.5
-
17
-
-
0035525784
-
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines
-
Fiumara P, Snell V, Li Y, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-2790.
-
(2001)
Blood
, vol.98
, pp. 2784-2790
-
-
Fiumara, P.1
Snell, V.2
Li, Y.3
-
18
-
-
0142182080
-
Receptor activator of nuclear factor kappaB ligand (RANKL)/ osteoprotegerin (OPG) ratio is increased in severe osteolysis
-
Grimaud E, Soubigou L, Couillaud S, et al. Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. Am J Pathol. 2003;163:2021-2031.
-
(2003)
Am J Pathol
, vol.163
, pp. 2021-2031
-
-
Grimaud, E.1
Soubigou, L.2
Couillaud, S.3
-
19
-
-
0035360265
-
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis
-
Morony S, Capparelli C, Sarosi I, Lacey DL, Dunstan CR, Kostenuik PJ. Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis. Cancer Res. 2001;61:4432-4436.
-
(2001)
Cancer Res
, vol.61
, pp. 4432-4436
-
-
Morony, S.1
Capparelli, C.2
Sarosi, I.3
Lacey, D.L.4
Dunstan, C.R.5
Kostenuik, P.J.6
-
20
-
-
23044509872
-
The RANKL Inhibitor Osteoprotegerin (OPG) causes greater suppression of bone resorption and hypercalcemia compared to bisphosphonates in two models of humoral hypercalcemia of malignancy
-
Morony S, Warmington K, Adamu S, et al. The RANKL Inhibitor Osteoprotegerin (OPG) causes greater suppression of bone resorption and hypercalcemia compared to bisphosphonates in two models of humoral hypercalcemia of malignancy. Endocrinology. 2005;146:3235-3543.
-
(2005)
Endocrinology
, vol.146
, pp. 3235-3543
-
-
Morony, S.1
Warmington, K.2
Adamu, S.3
-
21
-
-
0034105966
-
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord
-
Honore P, Luger NM, Sabino MC, et al. Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. Nat Med. 2000;6:521-528
-
(2000)
Nat Med
, vol.6
, pp. 521-528
-
-
Honore, P.1
Luger, N.M.2
Sabino, M.C.3
-
22
-
-
0037303260
-
RANK-Fc: A therapeutic antagonist for RANK-L in myeloma
-
Sordillo EM, Pearse RN. RANK-Fc: a therapeutic antagonist for RANK-L in myeloma. Cancer. 2003;97(3 Suppl):802-812.
-
(2003)
Cancer
, vol.97
, Issue.3 SUPPL.
, pp. 802-812
-
-
Sordillo, E.M.1
Pearse, R.N.2
-
23
-
-
0346837985
-
A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases
-
Body JJ, Greipp P, Coleman RE, et al. A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases. Cancer. 2003;97(3 Suppl):887-892.
-
(2003)
Cancer
, vol.97
, Issue.3 SUPPL.
, pp. 887-892
-
-
Body, J.J.1
Greipp, P.2
Coleman, R.E.3
-
24
-
-
0037086077
-
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells
-
Holen I, Croucher PI, Hamdy FC, Eaton CL. Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells. Cancer Res. 2002;62:1619-1623.
-
(2002)
Cancer Res
, vol.62
, pp. 1619-1623
-
-
Holen, I.1
Croucher, P.I.2
Hamdy, F.C.3
Eaton, C.L.4
-
25
-
-
0035021176
-
Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone
-
Zhang J, Dai J, Qi Y et al. Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. J Clin Invest. 2001;107:1235-1244.
-
(2001)
J Clin Invest
, vol.107
, pp. 1235-1244
-
-
Zhang, J.1
Dai, J.2
Qi, Y.3
-
26
-
-
12444300160
-
The effect of Osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft
-
Kiefer JA, Vessella RL, Quinn JE, et al. The effect of Osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft. Clin Exp Metastasis. 2004;21:381-387.
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 381-387
-
-
Kiefer, J.A.1
Vessella, R.L.2
Quinn, J.E.3
-
27
-
-
4043064387
-
Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: Diagnostic and prognostic implications
-
Jung K, Lein M, Stephan C, et al. Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications. Int J Cancer. 2004;111:783-791.
-
(2004)
Int J Cancer
, vol.111
, pp. 783-791
-
-
Jung, K.1
Lein, M.2
Stephan, C.3
-
28
-
-
27644458185
-
Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: Correlation with Gleason score
-
Guan M, Chen Y. Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: correlation with Gleason score. J Clin Pathol. 2005;58:1175-1179.
-
(2005)
J Clin Pathol
, vol.58
, pp. 1175-1179
-
-
Guan, M.1
Chen, Y.2
-
29
-
-
4444326415
-
Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
-
Chen G, Shukeir N, Potti A, et al. Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer. 2004;101:1345-1356.
-
(2004)
Cancer
, vol.101
, pp. 1345-1356
-
-
Chen, G.1
Shukeir, N.2
Potti, A.3
-
30
-
-
0036433659
-
Expression and somatic mutation on androgen receptor gene in prostate cancer
-
Segawa N, Nakamura M, Shan L, et al. Expression and somatic mutation on androgen receptor gene in prostate cancer. Int J Urol. 2002;9:545-553.
-
(2002)
Int J Urol
, vol.9
, pp. 545-553
-
-
Segawa, N.1
Nakamura, M.2
Shan, L.3
-
31
-
-
0035319658
-
Osteoprotegerin and rank ligand expression in prostate cancer
-
Brown JM, Corey E, Lee ZD, et al. Osteoprotegerin and rank ligand expression in prostate cancer. Urology. 2001;57:611-616.
-
(2001)
Urology
, vol.57
, pp. 611-616
-
-
Brown, J.M.1
Corey, E.2
Lee, Z.D.3
-
32
-
-
85058065867
-
Receptor activator of NK-kappaB ligand influences malignant activities of metastatic breast cancer cells
-
Ray MR, Allan AL, Tuck AB, Chambers AF. Receptor activator of NK-kappaB ligand influences malignant activities of metastatic breast cancer cells. J Bone Miner Res. 2005;20(Suppl 1):S1117.
-
(2005)
J Bone Miner Res
, vol.20
, Issue.SUPPL. 1
-
-
Ray, M.R.1
Allan, A.L.2
Tuck, A.B.3
Chambers, A.F.4
-
33
-
-
21144438505
-
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL
-
Lynch CC, Hikosaka A, Acuff HB, et al. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL. Cancer Cell. 2005;7:485-496.
-
(2005)
Cancer Cell
, vol.7
, pp. 485-496
-
-
Lynch, C.C.1
Hikosaka, A.2
Acuff, H.B.3
-
34
-
-
24644435593
-
Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo - A role in tumour cell survival?
-
Holen I, Cross SS, Neville-Webbe HL, et al. Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo-a role in tumour cell survival? Breast Cancer Res Treat. 2005;92:207-215.
-
(2005)
Breast Cancer Res Treat
, vol.92
, pp. 207-215
-
-
Holen, I.1
Cross, S.S.2
Neville-Webbe, H.L.3
-
35
-
-
0041854146
-
Expression of Osteoprotegerin correlates with aggressiveness and poor prognosis of gastric carcinoma
-
Ito R, Nakayama H, Yoshida K, et al. Expression of Osteoprotegerin correlates with aggressiveness and poor prognosis of gastric carcinoma. Virchows Arch. 2003;443:146-151.
-
(2003)
Virchows Arch
, vol.443
, pp. 146-151
-
-
Ito, R.1
Nakayama, H.2
Yoshida, K.3
-
36
-
-
4744340115
-
Prognostic significance of serum osteoprotegerin levels in patients with bladder carcinoma
-
Mizutani Y, Matsubara H, Yamamoto K, et al. Prognostic significance of serum osteoprotegerin levels in patients with bladder carcinoma. Cancer. 2004;101:1794-1802
-
(2004)
Cancer
, vol.101
, pp. 1794-1802
-
-
Mizutani, Y.1
Matsubara, H.2
Yamamoto, K.3
-
37
-
-
11344267803
-
Prostate cancer bone metastases promote both osteolytic and osteoblastic activity
-
Keller ET, Brown J. Prostate cancer bone metastases promote both osteolytic and osteoblastic activity. J Cell Biochem. 2004;91:718-729.
-
(2004)
J Cell Biochem
, vol.91
, pp. 718-729
-
-
Keller, E.T.1
Brown, J.2
-
38
-
-
16444368652
-
Osteoprotegerin in prostate cancer bone metastasis
-
Corey E, Brown LG, Kiefer JA, et al. Osteoprotegerin in prostate cancer bone metastasis. Cancer Res. 2005;65:1710-1718.
-
(2005)
Cancer Res
, vol.65
, pp. 1710-1718
-
-
Corey, E.1
Brown, L.G.2
Kiefer, J.A.3
-
39
-
-
0142026185
-
Receptor activator of nuclear factor kappaB (RANK) is expressed as a late event during malignant progression in Barrett's metaplasia
-
Yorke R, Younes A, Chirala M, Younes M. Receptor activator of nuclear factor kappaB (RANK) is expressed as a late event during malignant progression in Barrett's metaplasia. Eur J Cancer. 2003;39:2099-2102.
-
(2003)
Eur J Cancer
, vol.39
, pp. 2099-2102
-
-
Yorke, R.1
Younes, A.2
Chirala, M.3
Younes, M.4
-
40
-
-
16444377384
-
Fc-OPG inhibits osteoclast activity while tumor-derived OPG enhances tumor growth
-
Abstract
-
Fisher JL, Thomas-Mudge RJ, Elliot J, et al. Fc-OPG inhibits osteoclast activity while tumor-derived OPG enhances tumor growth. J Bone Miner Res. 2003;18:S63. Abstract.
-
(2003)
J Bone Miner Res
, vol.18
-
-
Fisher, J.L.1
Thomas-Mudge, R.J.2
Elliot, J.3
|