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Volumn 28, Issue 5, 2013, Pages 711-720

Endothelin antagonists in hypertension and kidney disease

Author keywords

Chronic kidney disease; Endothelin A receptor; Endothelin B receptor; Endothelin 1; Endothelin converting enzyme 1

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; 3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; AMBRISENTAN; ATRASENTAN; BOSENTAN; BQ 610; CGS 35066; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DARUSENTAN; ENALAPRIL; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; ENRASENTAN; IPI 725; L 744453; L 751281; L 754142; MACITENTAN; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N ACETYL 10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTEN 5 YLGLYCYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; PHOSPHORAMIDON; PLACEBO; RES 011; RO 468443; SITAXSENTAN; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE]; TAK 044; TEZOSENTAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIBOTENTAN;

EID: 84880570863     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-012-2316-4     Document Type: Review
Times cited : (27)

References (75)
  • 2
    • 0027164084 scopus 로고
    • Sarafotoxins and endothelins: Evolution, structure and function
    • 8332988 10.1016/0041-0101(93)90111-U 1:CAS:528:DyaK3sXksVarsbw%3D
    • Kochva E, Bdolah A, Wollberg Z (1993) Sarafotoxins and endothelins: evolution, structure and function. Toxicon 31:541-568
    • (1993) Toxicon , vol.31 , pp. 541-568
    • Kochva, E.1    Bdolah, A.2    Wollberg, Z.3
  • 3
    • 0025805940 scopus 로고
    • Chromosomal assignments of the human endothelin family genes: The endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3
    • 2018043 1:CAS:528:DyaK3MXkvVKmsrg%3D
    • Arinami T, Ishikawa M, Inoue A, Yanagisawa M, Masaki T, Yoshida M, Hamaguchi H (1991) Chromosomal assignments of the human endothelin family genes: the endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3. Am J Hum Genet 48:990-996
    • (1991) Am J Hum Genet , vol.48 , pp. 990-996
    • Arinami, T.1    Ishikawa, M.2    Inoue, A.3    Yanagisawa, M.4    Masaki, T.5    Yoshida, M.6    Hamaguchi, H.7
  • 4
    • 0025790420 scopus 로고
    • The gene for the novel vasoactive peptide endothelin 3 (EDN3) is localized to human chromosome 20q13.2-qter
    • 1889823 10.1016/0888-7543(91)90472-Q 1:CAS:528:DyaK3MXmtVSjs7k%3D
    • Rao V, Löffler C, Hansmann I (1991) The gene for the novel vasoactive peptide endothelin 3 (EDN3) is localized to human chromosome 20q13.2-qter. Genomics 10:840-841
    • (1991) Genomics , vol.10 , pp. 840-841
    • Rao, V.1    Löffler, C.2    Hansmann, I.3
  • 7
    • 0024427985 scopus 로고
    • The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression
    • 2670930 1:CAS:528:DyaK3cXktlGlsL8%3D
    • Inoue A, Yanagisawa M, Takuwa Y, Mitsui Y, Kobayashi M, Masaki T (1989) The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression. J Biol Chem 264:14954-14959
    • (1989) J Biol Chem , vol.264 , pp. 14954-14959
    • Inoue, A.1    Yanagisawa, M.2    Takuwa, Y.3    Mitsui, Y.4    Kobayashi, M.5    Masaki, T.6
  • 8
    • 79251592532 scopus 로고    scopus 로고
    • Endothelin-1 gene regulation
    • 20837776 10.1096/fj.10-161612 1:CAS:528:DC%2BC3MXls1Gguw%3D%3D
    • Stow L, Jacobs M, Wingo C, Cain B (2011) Endothelin-1 gene regulation. FASEB J 25:16-28
    • (2011) FASEB J , vol.25 , pp. 16-28
    • Stow, L.1    Jacobs, M.2    Wingo, C.3    Cain, B.4
  • 9
    • 59649085140 scopus 로고    scopus 로고
    • Chymase-dependent conversion of Big endothelin-1 in the mouse in vivo
    • 18987301 10.1124/jpet.108.142992 1:CAS:528:DC%2BD1MXhs1Khu7c%3D
    • Simard E, Jin D, Takai S, Miyazaki M, Brochu I, D'Orleans-Juste P (2009) Chymase-dependent conversion of Big endothelin-1 in the mouse in vivo. J Pharmacol Exp Ther 328:540-548
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 540-548
    • Simard, E.1    Jin, D.2    Takai, S.3    Miyazaki, M.4    Brochu, I.5    D'Orleans-Juste, P.6
  • 10
    • 0027992642 scopus 로고
    • ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1
    • 8062389 10.1016/0092-8674(94)90425-1 1:CAS:528:DyaK2MXkvV2nug%3D%3D
    • Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, deWit D, Yanagisawa M (1994) ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 78:473-485
    • (1994) Cell , vol.78 , pp. 473-485
    • Xu, D.1    Emoto, N.2    Giaid, A.3    Slaughter, C.4    Kaw, S.5    Dewit, D.6    Yanagisawa, M.7
  • 12
    • 0030032386 scopus 로고    scopus 로고
    • Molecular pharmacology of endothelin converting enzymes
    • 10.1016/0006-2952(95)02036-5
    • Turner AJ, Murphy LJ (1996) Molecular pharmacology of endothelin converting enzymes. Biochem Pharmacol 26:91-102
    • (1996) Biochem Pharmacol , vol.26 , pp. 91-102
    • Turner, A.J.1    Murphy, L.J.2
  • 13
    • 0029741347 scopus 로고    scopus 로고
    • Human pulmonary circulation is an important site for both clearance and production of endothelin-1
    • 8840847 10.1161/01.CIR.94.7.1578 1:CAS:528:DyaK28XmsFSntL8%3D
    • Dupuis J, Stewart DJ, Cernacek P, Gosselin G (1996) Human pulmonary circulation is an important site for both clearance and production of endothelin-1. Circulation 94:1578-1584
    • (1996) Circulation , vol.94 , pp. 1578-1584
    • Dupuis, J.1    Stewart, D.J.2    Cernacek, P.3    Gosselin, G.4
  • 14
    • 0025368480 scopus 로고
    • Endothelium-derived vasoactive factors and regulation of vascular tone in human blood vessels
    • 2166886 10.1007/BF02718110
    • Luscher TF (1990) Endothelium-derived vasoactive factors and regulation of vascular tone in human blood vessels. Lung 168:27-34
    • (1990) Lung , vol.168 , pp. 27-34
    • Luscher, T.F.1
  • 15
    • 0033160038 scopus 로고    scopus 로고
    • Endothelin receptor antagonists. Promising new agents in the management of cardiovascular disorders
    • 10560541 10.2165/00126839-199902010-00001 1:CAS:528:DyaK1MXmt1Sjtrs%3D
    • Goddard J, Webb DJ (1999) Endothelin receptor antagonists. Promising new agents in the management of cardiovascular disorders. Drugs R D 2:1-12
    • (1999) Drugs R D , vol.2 , pp. 1-12
    • Goddard, J.1    Webb, D.J.2
  • 16
    • 0029585975 scopus 로고
    • Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)
    • 8530372 10.1074/jbc.270.50.29794 1:CAS:528:DyaK2MXhtVSitbrP
    • Valdenaire O, Rohrbacher E, Mattei MG (1995) Organization of the gene encoding the human endothelin-converting enzyme (ECE-1). J Biol Chem 270:29794-29798
    • (1995) J Biol Chem , vol.270 , pp. 29794-29798
    • Valdenaire, O.1    Rohrbacher, E.2    Mattei, M.G.3
  • 17
    • 18744386101 scopus 로고    scopus 로고
    • A New class of inhibitors for the metalloprotease neprilysin based on a Central Imidazole Scaffold
    • 10.1002/hlca.200590050 1:CAS:528:DC%2BD2MXktFSmsrY%3D
    • Sahli S, Stump B, Welti T, Schweizer WB, Diederich F, Blum-Kaelin D, Aebi JD, Böhm HJ (2005) A New class of inhibitors for the metalloprotease neprilysin based on a Central Imidazole Scaffold. Helv Chim Acta 88:707-730
    • (2005) Helv Chim Acta , vol.88 , pp. 707-730
    • Sahli, S.1    Stump, B.2    Welti, T.3    Schweizer, W.B.4    Diederich, F.5    Blum-Kaelin, D.6    Aebi, J.D.7    Böhm, H.J.8
  • 18
    • 28844505349 scopus 로고    scopus 로고
    • Endothelin-converting enzyme-1, abundance of isoforms a-d and identification of a novel alternatively spliced variant lacking a transmembrane domain
    • 16186113 10.1074/jbc.M505679200 1:CAS:528:DC%2BD2MXht1Oqt7%2FK
    • Meidan R, Klipper E, Gilboa T, Muller L, Levy N (2005) Endothelin-converting enzyme-1, abundance of isoforms a-d and identification of a novel alternatively spliced variant lacking a transmembrane domain. J Biol Chem 280:40867-40874
    • (2005) J Biol Chem , vol.280 , pp. 40867-40874
    • Meidan, R.1    Klipper, E.2    Gilboa, T.3    Muller, L.4    Levy, N.5
  • 19
    • 33744915776 scopus 로고    scopus 로고
    • Identification of a novel alternatively spliced variant endothelin converting enzyme-1 lacking a transmembrane domain
    • 1:CAS:528:DC%2BD28Xlt1ersr4%3D
    • Klipper E, Levy N, Gilboa T, Muller L, Meidan R (2006) Identification of a novel alternatively spliced variant endothelin converting enzyme-1 lacking a transmembrane domain. Exp Biol Med (Maywood) 231:723-728
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 723-728
    • Klipper, E.1    Levy, N.2    Gilboa, T.3    Muller, L.4    Meidan, R.5
  • 20
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • 2175396 10.1038/348730a0 1:CAS:528:DyaK3MXktVaisb0%3D
    • Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S (1990) Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348:730-732
    • (1990) Nature , vol.348 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 21
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • 2175397 10.1038/348732a0 1:CAS:528:DyaK3MXktVaisbo%3D
    • Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T (1990) Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 348:732-735
    • (1990) Nature , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3    Miyazaki, H.4    Kimura, S.5    Goto, K.6    Masaki, T.7
  • 22
    • 0033580697 scopus 로고    scopus 로고
    • Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation
    • 10364236 10.1074/jbc.274.25.17901 1:CAS:528:DyaK1MXktVylsLg%3D
    • Gohla A, Offermanns S, Wilkie TM, Schultz G (1999) Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation. J Biol Chem 274:17901-17907
    • (1999) J Biol Chem , vol.274 , pp. 17901-17907
    • Gohla, A.1    Offermanns, S.2    Wilkie, T.M.3    Schultz, G.4
  • 23
    • 0032980752 scopus 로고    scopus 로고
    • Subcellular mechanisms of endothelin action in vascular system
    • 10443571 10.1016/S0014-2999(99)00252-6 1:CAS:528:DyaK1MXks1CrsrY%3D
    • Masaki T, Miwa S, Sawamura T, Ninomiya H, Okamoto Y (1999) Subcellular mechanisms of endothelin action in vascular system. Eur J Pharmacol 375:133-138
    • (1999) Eur J Pharmacol , vol.375 , pp. 133-138
    • Masaki, T.1    Miwa, S.2    Sawamura, T.3    Ninomiya, H.4    Okamoto, Y.5
  • 24
    • 0036156350 scopus 로고    scopus 로고
    • Molecular mechanism for endothelin-1-induced stress-fiber formation: Analysis of G proteins using a mutant endothelin(A) receptor
    • 11809851 10.1124/mol.61.2.277 1:CAS:528:DC%2BD38Xos1Oiuw%3D%3D
    • Kawanabe Y, Okamoto Y, Nozaki K, Hashimoto N, Miwa S, Masaki T (2002) Molecular mechanism for endothelin-1-induced stress-fiber formation: analysis of G proteins using a mutant endothelin(A) receptor. Mol Pharmacol 61:277-284
    • (2002) Mol Pharmacol , vol.61 , pp. 277-284
    • Kawanabe, Y.1    Okamoto, Y.2    Nozaki, K.3    Hashimoto, N.4    Miwa, S.5    Masaki, T.6
  • 25
    • 0036085650 scopus 로고    scopus 로고
    • Molecular mechanisms for the activation of voltage-independent Ca2+ channels by endothelin-1 in Chinese hamster ovary cells stably expressing human endothelin(A) receptors
    • 12065757 10.1124/mol.62.1.75 1:CAS:528:DC%2BD38Xlt1Kqtb8%3D
    • Kawanabe Y, Okamoto Y, Miwa S, Hashimoto N, Masaki T (2002) Molecular mechanisms for the activation of voltage-independent Ca2+ channels by endothelin-1 in Chinese hamster ovary cells stably expressing human endothelin(A) receptors. Mol Pharmacol 62:75-80
    • (2002) Mol Pharmacol , vol.62 , pp. 75-80
    • Kawanabe, Y.1    Okamoto, Y.2    Miwa, S.3    Hashimoto, N.4    Masaki, T.5
  • 26
    • 0036765311 scopus 로고    scopus 로고
    • Effects of phosphoinositide 3-kinase on the endothelin-1-induced activation of voltage-independent Ca(2+) channels and mitogenesis in Chinese hamster ovary cells stably expressing endothelin(a) receptor
    • 12181454 10.1124/mol.62.3.756 1:CAS:528:DC%2BD38XmsVKlsr8%3D
    • Kawanabe Y, Hashimoto N, Masaki T (2002) Effects of phosphoinositide 3-kinase on the endothelin-1-induced activation of voltage-independent Ca(2+) channels and mitogenesis in Chinese hamster ovary cells stably expressing endothelin(a) receptor. Mol Pharmacol 62:756-761
    • (2002) Mol Pharmacol , vol.62 , pp. 756-761
    • Kawanabe, Y.1    Hashimoto, N.2    Masaki, T.3
  • 27
    • 0028788150 scopus 로고
    • Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: Relation to hemodynamic variables and endothelin levels
    • 7594089 10.1016/0735-1097(95)00399-1 1:CAS:528:DyaK28XlvFCquw%3D%3D
    • Nootens M, Kaufmann E, Rector T, Toher C, Judd D, Francis GS, Rich S (1995) Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels. J Am Coll Cardiol 26:1581-1585
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1581-1585
    • Nootens, M.1    Kaufmann, E.2    Rector, T.3    Toher, C.4    Judd, D.5    Francis, G.S.6    Rich, S.7
  • 28
    • 0026034713 scopus 로고
    • Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease?
    • 1994793 1:STN:280:DyaK3M7js1SmsA%3D%3D
    • Stewart DJ, Levy RD, Cernacek P, Langleben D (1991) Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med 114:464-469
    • (1991) Ann Intern Med , vol.114 , pp. 464-469
    • Stewart, D.J.1    Levy, R.D.2    Cernacek, P.3    Langleben, D.4
  • 30
    • 0033844691 scopus 로고    scopus 로고
    • Endothelin A receptor blockade prevents capillary/myocyte mismatch in the heart of uremic animals
    • 10966495 1:CAS:528:DC%2BD3cXntFKru7s%3D
    • Amann K, Munter K, Wessels S, Wagner J, Balajew V, Hergenroder S, Mall G, Ritz E (2000) Endothelin A receptor blockade prevents capillary/myocyte mismatch in the heart of uremic animals. J Am Soc Nephrol 11:1702-1711
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1702-1711
    • Amann, K.1    Munter, K.2    Wessels, S.3    Wagner, J.4    Balajew, V.5    Hergenroder, S.6    Mall, G.7    Ritz, E.8
  • 31
    • 78649864855 scopus 로고    scopus 로고
    • At the heart of tissue: Endothelin system and end-organ damage
    • 10.1042/CS20100222 1:CAS:528:DC%2BC3cXhtVKiu7%2FE
    • Iglarz M, Clozel M (2010) At the heart of tissue: endothelin system and end-organ damage. Clin Sci (Lond) 119:453-463
    • (2010) Clin Sci (Lond) , vol.119 , pp. 453-463
    • Iglarz, M.1    Clozel, M.2
  • 32
    • 33845423984 scopus 로고    scopus 로고
    • Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention
    • 16868309 10.1152/ajprenal.00190.2006 1:CAS:528:DC%2BD2sXktV2j
    • Ge Y, Bagnall A, Stricklett PK, Strait K, Webb DJ, Kotelevtsev Y, Kohan DE (2006) Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. Am J Physiol Renal Physiol 291:F1274-F1280
    • (2006) Am J Physiol Renal Physiol , vol.291
    • Ge, Y.1    Bagnall, A.2    Stricklett, P.K.3    Strait, K.4    Webb, D.J.5    Kotelevtsev, Y.6    Kohan, D.E.7
  • 33
    • 34548172512 scopus 로고    scopus 로고
    • Chronic activation of endothelin B receptors: New model of experimental hypertension
    • 17664390 10.1161/HYPERTENSIONAHA.107.094821 1:CAS:528: DC%2BD2sXptlykt70%3D
    • Fink G, Li M, Lau Y, Osborn J, Watts S (2007) Chronic activation of endothelin B receptors: new model of experimental hypertension. Hypertension 50:512-518
    • (2007) Hypertension , vol.50 , pp. 512-518
    • Fink, G.1    Li, M.2    Lau, Y.3    Osborn, J.4    Watts, S.5
  • 34
    • 1542514709 scopus 로고    scopus 로고
    • Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: A comparison of selective and combined endothelin receptor blockade
    • 14981006 10.1161/01.CIR.0000118499.69469.51 1:CAS:528: DC%2BD2cXhs12kt7w%3D
    • Goddard J, Johnston NR, Hand MF, Cumming AD, Rabelink TJ, Rankin AJ, Webb DJ (2004) Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: a comparison of selective and combined endothelin receptor blockade. Circulation 109:1186-1193
    • (2004) Circulation , vol.109 , pp. 1186-1193
    • Goddard, J.1    Johnston, N.R.2    Hand, M.F.3    Cumming, A.D.4    Rabelink, T.J.5    Rankin, A.J.6    Webb, D.J.7
  • 35
    • 0036004052 scopus 로고    scopus 로고
    • Role of endothelin in cardiovascular disease
    • 11984741 10.3317/jraas.2002.001 1:CAS:528:DC%2BD38Xjs1Knu7c%3D
    • Agapitov AV, Haynes WG (2002) Role of endothelin in cardiovascular disease. J Renin Angiotensin Aldosterone Syst 3:1-15
    • (2002) J Renin Angiotensin Aldosterone Syst , vol.3 , pp. 1-15
    • Agapitov, A.V.1    Haynes, W.G.2
  • 37
    • 79960444557 scopus 로고    scopus 로고
    • SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: The CARDIA Fitness Study
    • 20944660 10.1038/jhh.2010.94 1:CAS:528:DC%2BC3MXovFOiu7o%3D
    • Sarzynski MA, Rankinen T, Sternfeld B, Fornage M, Sidney S, Bouchard C (2011) SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CARDIA Fitness Study. J Hum Hypertens 25:509-518
    • (2011) J Hum Hypertens , vol.25 , pp. 509-518
    • Sarzynski, M.A.1    Rankinen, T.2    Sternfeld, B.3    Fornage, M.4    Sidney, S.5    Bouchard, C.6
  • 38
    • 78650200856 scopus 로고    scopus 로고
    • Contrasting effects of intervention with ETA and ETB receptor antagonists in hypertension induced by angiotensin II and high-salt diet
    • 20725138 10.1139/Y10-051 1:CAS:528:DC%2BC3cXpsFyiurs%3D
    • Boesen EI, Pollock JS, Pollock DM (2010) Contrasting effects of intervention with ETA and ETB receptor antagonists in hypertension induced by angiotensin II and high-salt diet. Can J Physiol Pharmacol 88:802-807
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 802-807
    • Boesen, E.I.1    Pollock, J.S.2    Pollock, D.M.3
  • 39
    • 78651238433 scopus 로고    scopus 로고
    • Impaired stimulatory effect of ETB receptor on D receptor in immortalized renal proximal tubule cells of spontaneously hypertensive rats
    • 21228598 10.1159/000323135
    • Zhang Y, Fu C, Ren H, He D, Wang X, Asico LD, Jose PA, Zeng C (2011) Impaired stimulatory effect of ETB receptor on D receptor in immortalized renal proximal tubule cells of spontaneously hypertensive rats. Kidney Blood Press Res 34:75-82
    • (2011) Kidney Blood Press Res , vol.34 , pp. 75-82
    • Zhang, Y.1    Fu, C.2    Ren, H.3    He, D.4    Wang, X.5    Asico, L.D.6    Jose, P.A.7    Zeng, C.8
  • 42
    • 79953192548 scopus 로고    scopus 로고
    • Endothelin-1 increases collagen accumulation in renal mesangial cells by stimulating a chemokine and cytokine autocrine signaling loop
    • 21169360 10.1074/jbc.M110.190793 1:CAS:528:DC%2BC3MXjslKhu78%3D
    • Simonson MS, Ismail-Beigi F (2011) Endothelin-1 increases collagen accumulation in renal mesangial cells by stimulating a chemokine and cytokine autocrine signaling loop. J Biol Chem 286:11003-11008
    • (2011) J Biol Chem , vol.286 , pp. 11003-11008
    • Simonson, M.S.1    Ismail-Beigi, F.2
  • 43
    • 0034101906 scopus 로고    scopus 로고
    • Mechanisms of big endothelin-1-induced diuresis and natriuresis: Role of ET(B) receptors
    • 10720587 10.1161/01.HYP.35.3.732 1:CAS:528:DC%2BD3cXit12qt74%3D
    • Hoffman A, Abassi ZA, Brodsky S, Ramadan R, Winaver J (2000) Mechanisms of big endothelin-1-induced diuresis and natriuresis: role of ET(B) receptors. Hypertension 35:732-739
    • (2000) Hypertension , vol.35 , pp. 732-739
    • Hoffman, A.1    Abassi, Z.A.2    Brodsky, S.3    Ramadan, R.4    Winaver, J.5
  • 44
    • 78649972833 scopus 로고    scopus 로고
    • Cooperative role of ETA and ETB receptors in mediating the diuretic response to intramedullary hyperosmotic NaCl infusion
    • 20844020 10.1152/ajprenal.00015.2010 1:CAS:528:DC%2BC3cXhs1elsb7L
    • Boesen EI, Pollock DM (2010) Cooperative role of ETA and ETB receptors in mediating the diuretic response to intramedullary hyperosmotic NaCl infusion. Am J Physiol Renal Physiol 299:F1424-F1432
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Boesen, E.I.1    Pollock, D.M.2
  • 45
    • 0033032954 scopus 로고    scopus 로고
    • Differential effects of endothelin-1 antagonists on erythropoietin- induced hypertension in renal failure
    • 10405199 1:CAS:528:DyaK1MXktlKhur4%3D
    • Brochu E, Lacasse S, Lariviere R, Kingma I, Grose JH, Lebel M (1999) Differential effects of endothelin-1 antagonists on erythropoietin-induced hypertension in renal failure. J Am Soc Nephrol 10:1440-1446
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1440-1446
    • Brochu, E.1    Lacasse, S.2    Lariviere, R.3    Kingma, I.4    Grose, J.H.5    Lebel, M.6
  • 46
    • 0028187959 scopus 로고
    • Effects of selective endothelin antagonists on the hemodynamic response to cyclosporin A
    • 8161726 1:CAS:528:DyaK2cXkt1Kntb0%3D
    • Davis LS, Haleen SJ, Doherty AM, Cody WL, Keiser JA (1994) Effects of selective endothelin antagonists on the hemodynamic response to cyclosporin A. J Am Soc Nephrol 4:1448-1454
    • (1994) J Am Soc Nephrol , vol.4 , pp. 1448-1454
    • Davis, L.S.1    Haleen, S.J.2    Doherty, A.M.3    Cody, W.L.4    Keiser, J.A.5
  • 47
    • 84867582858 scopus 로고    scopus 로고
    • Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues
    • 10.1016/j.lfs.2012.05.008
    • Maguire JJ, Kuc RE, Davenport AP (2012) Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues. Life Sci. doi: 10.1016/j.lfs.2012.05.008
    • (2012) Life Sci
    • Maguire, J.J.1    Kuc, R.E.2    Davenport, A.P.3
  • 48
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomised placebo-controlled study
    • 11597664 10.1016/S0140-6736(01)06250-X 1:CAS:528:DC%2BD3MXntlOrurs%3D
    • Channick RN, Simonneau G, Sitbon O, Robbins IM, Frost A, Tapson VF, Badesch DB, Roux S, Rainisio M, Bodin F, Rubin LJ (2001) Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 358:1119-1123
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3    Robbins, I.M.4    Frost, A.5    Tapson, V.F.6    Badesch, D.B.7    Roux, S.8    Rainisio, M.9    Bodin, F.10    Rubin, L.J.11
  • 51
    • 67349277689 scopus 로고    scopus 로고
    • Endothelin receptor blockade in the management of pulmonary arterial hypertension: Selective and dual antagonism
    • 19304472 10.1016/j.rmed.2009.02.016
    • Trow TK, Taichman DB (2009) Endothelin receptor blockade in the management of pulmonary arterial hypertension: selective and dual antagonism. Respir Med 103:951-962
    • (2009) Respir Med , vol.103 , pp. 951-962
    • Trow, T.K.1    Taichman, D.B.2
  • 52
    • 0033854558 scopus 로고    scopus 로고
    • Hypertension in black patients: An emerging role of the endothelin system in salt-sensitive hypertension
    • 10904013 10.1161/01.HYP.36.1.62 1:CAS:528:DC%2BD3cXlslehur8%3D
    • Ergul A (2000) Hypertension in black patients: an emerging role of the endothelin system in salt-sensitive hypertension. Hypertension 36:62-67
    • (2000) Hypertension , vol.36 , pp. 62-67
    • Ergul, A.1
  • 53
    • 0032546259 scopus 로고    scopus 로고
    • The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators
    • 9504938 10.1056/NEJM199803193381202 1:CAS:528:DyaK1cXitlChtbs%3D
    • Krum H, Viskoper RJ, Lacourciere Y, Budde M, Charlon V (1998) The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators. N Engl J Med 338:784-790
    • (1998) N Engl J Med , vol.338 , pp. 784-790
    • Krum, H.1    Viskoper, R.J.2    Lacourciere, Y.3    Budde, M.4    Charlon, V.5
  • 54
    • 70350133404 scopus 로고    scopus 로고
    • A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: A randomised, double-blind, placebo-controlled trial
    • 19748665 10.1016/S0140-6736(09)61500-2 1:CAS:528:DC%2BD1MXhtlSru7jK
    • Weber MA, Black H, Bakris G, Krum H, Linas S, Weiss R, Linseman JV, Wiens BL, Warren MS, Lindholm LH (2009) A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial. Lancet 374:1423-1431
    • (2009) Lancet , vol.374 , pp. 1423-1431
    • Weber, M.A.1    Black, H.2    Bakris, G.3    Krum, H.4    Linas, S.5    Weiss, R.6    Linseman, J.V.7    Wiens, B.L.8    Warren, M.S.9    Lindholm, L.H.10
  • 55
    • 68049088897 scopus 로고    scopus 로고
    • Endothelin as a clinical target in the treatment of systemic hypertension
    • 19525680 10.1097/CRD.0b013e3181aa8f4a
    • Prasad VS, Palaniswamy C, Frishman WH (2009) Endothelin as a clinical target in the treatment of systemic hypertension. Cardiol Rev 17:181-191
    • (2009) Cardiol Rev , vol.17 , pp. 181-191
    • Prasad, V.S.1    Palaniswamy, C.2    Frishman, W.H.3
  • 57
    • 79959526176 scopus 로고    scopus 로고
    • Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease
    • 21471190 10.1124/jpet.111.178988 1:CAS:528:DC%2BC3MXosFChsrs%3D
    • Saleh MA, Pollock JS, Pollock DM (2011) Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J Pharmacol Exp Ther 338:263-270
    • (2011) J Pharmacol Exp Ther , vol.338 , pp. 263-270
    • Saleh, M.A.1    Pollock, J.S.2    Pollock, D.M.3
  • 58
    • 62149126622 scopus 로고    scopus 로고
    • Avosentan reduces albumin excretion in diabetics with macroalbuminuria
    • SPP301 (Avosentan) Endothelin Antagonist Evaluation in Diabetic Nephropathy Study Investigators 19144760 10.1681/ASN.2008050482
    • Wenzel RR, Littke T, Kuranoff S, Jurgens C, Bruck H, Ritz E, Philipp T, Mitchell A, SPP301 (Avosentan) Endothelin Antagonist Evaluation in Diabetic Nephropathy Study Investigators (2009) Avosentan reduces albumin excretion in diabetics with macroalbuminuria. J Am Soc Nephrol 20:655-664
    • (2009) J Am Soc Nephrol , vol.20 , pp. 655-664
    • Wenzel, R.R.1    Littke, T.2    Kuranoff, S.3    Jurgens, C.4    Bruck, H.5    Ritz, E.6    Philipp, T.7    Mitchell, A.8
  • 59
    • 84856047617 scopus 로고    scopus 로고
    • Endothelin but not angiotensin II may mediate hypertension-induced coronary vascular calcification in chronic kidney disease
    • 10.4061/2011/516237 21747998
    • Rabkin SW (2011) Endothelin but not angiotensin II may mediate hypertension-induced coronary vascular calcification in chronic kidney disease. Int J Nephrol doi: 10.4061/2011/516237
    • (2011) Int J Nephrol
    • Rabkin, S.W.1
  • 60
    • 79960077202 scopus 로고    scopus 로고
    • Endothelin receptor A antagonism attenuates renal medullary blood flow impairment in endotoxemic pigs
    • 21760895 10.1371/journal.pone.0021534 1:CAS:528:DC%2BC3MXps1Churs%3D
    • Fenhammar J, Andersson A, Forestier J, Weitzberg E, Sollevi A, Hjelmqvist H, Frithiof R (2011) Endothelin receptor A antagonism attenuates renal medullary blood flow impairment in endotoxemic pigs. PLoS One 6:e21534
    • (2011) PLoS One , vol.6 , pp. 21534
    • Fenhammar, J.1    Andersson, A.2    Forestier, J.3    Weitzberg, E.4    Sollevi, A.5    Hjelmqvist, H.6    Frithiof, R.7
  • 62
    • 70349841844 scopus 로고    scopus 로고
    • Tezosentan reduces the renal injury induced by abdominal aortic ischemia-reperfusion in rats
    • 19329125 10.1016/j.jss.2008.08.011 1:CAS:528:DC%2BD1MXht1Oru7nL
    • Gulmen S, Kiris I, Narin C, Ceylan BG, Mermi B, Sutcu R, Meteoglu I (2009) Tezosentan reduces the renal injury induced by abdominal aortic ischemia-reperfusion in rats. J Surg Res 157:e7-e13
    • (2009) J Surg Res , vol.157
    • Gulmen, S.1    Kiris, I.2    Narin, C.3    Ceylan, B.G.4    Mermi, B.5    Sutcu, R.6    Meteoglu, I.7
  • 63
    • 84867581354 scopus 로고    scopus 로고
    • Involvement of the endothelin and nitric oxide systems in the pathogenesis of renal ischemic damage in an experimental diabetic model
    • 10.1016/j.lfs.2012.02.002 22365956
    • Abu-Saleh N, Ovcharenko E, Awad H, Goltsman I, Khamaisi M, Hoffman A, Heyman SN, Winaver J, Abassi Z (2012) Involvement of the endothelin and nitric oxide systems in the pathogenesis of renal ischemic damage in an experimental diabetic model. Life Sci. doi: 10.1016/j.lfs.2012.02.002
    • (2012) Life Sci
    • Abu-Saleh, N.1    Ovharenko, E.2    Awad, H.3    Goltsman, I.4    Khamaisi, M.5    Hoffman, A.6    Heyman, S.N.7    Winaver, J.8    Abassi, Z.9
  • 64
    • 84867418316 scopus 로고    scopus 로고
    • Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD)
    • 10.1016/j.lfs.2012.01.011 22326504
    • Andress D, Coll B, Pritchett Y, Brennan J, Molitch M, Kohan D (2012) Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD). Life Sci. doi: 10.1016/j.lfs.2012.01.011
    • (2012) Life Sci
    • Andress, D.1    Coll, B.2    Pritchett, Y.3    Brennan, J.4    Molitch, M.5    Kohan, D.6
  • 66
    • 39149133153 scopus 로고    scopus 로고
    • Stimulation of endothelin-1 gene expression by insulin via phosphoinositide-3 kinase-glycogen synthase kinase-3beta signaling in endothelial cells
    • 18201727 10.1016/j.lfs.2007.12.005 1:CAS:528:DC%2BD1cXitVeis7k%3D
    • Yang Z, Li JC (2008) Stimulation of endothelin-1 gene expression by insulin via phosphoinositide-3 kinase-glycogen synthase kinase-3beta signaling in endothelial cells. Life Sci 82:512-518
    • (2008) Life Sci , vol.82 , pp. 512-518
    • Yang, Z.1    Li, J.C.2
  • 67
    • 56749168571 scopus 로고    scopus 로고
    • Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK
    • 19029977 10.1038/bjp.2008.327 1:CAS:528:DC%2BD1cXhsVWgsr7K
    • Kobayashi T, Nogami T, Taguchi K, Matsumoto T, Kamata K (2008) Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK. Br J Pharmacol 155:974-983
    • (2008) Br J Pharmacol , vol.155 , pp. 974-983
    • Kobayashi, T.1    Nogami, T.2    Taguchi, K.3    Matsumoto, T.4    Kamata, K.5
  • 68
    • 77649234517 scopus 로고    scopus 로고
    • Short-term angiotensin-1 receptor antagonism in type 2 diabetic Goto-Kakizaki rats normalizes endothelin-1-induced mesenteric artery contraction
    • 10.1016/j.peptides.2009.12.017
    • Matsumoto T, Ishida K, Taguchi K, Kobayashi T, Kamata K (2010) Short-term angiotensin-1 receptor antagonism in type 2 diabetic Goto-Kakizaki rats normalizes endothelin-1-induced mesenteric artery contraction. Peptides 4:609-617
    • (2010) Peptides , vol.4 , pp. 609-617
    • Matsumoto, T.1    Ishida, K.2    Taguchi, K.3    Kobayashi, T.4    Kamata, K.5
  • 69
    • 58149105516 scopus 로고    scopus 로고
    • Role of angiotensin II, endothelin-1 and L-type calcium channel in the development of glomerular, tubulointerstitial and perivascular fibrosis
    • 18806627 10.1097/HJH.0b013e328309f00a 1:CAS:528:DC%2BD1cXhtFCju7zL
    • Seccia TM, Maniero C, Belloni AS, Guidolin D, Pothen P, Pessina AC, Rossi GP (2008) Role of angiotensin II, endothelin-1 and L-type calcium channel in the development of glomerular, tubulointerstitial and perivascular fibrosis. J Hypertens 26:2022-2029
    • (2008) J Hypertens , vol.26 , pp. 2022-2029
    • Seccia, T.M.1    Maniero, C.2    Belloni, A.S.3    Guidolin, D.4    Pothen, P.5    Pessina, A.C.6    Rossi, G.P.7
  • 71
    • 79953295959 scopus 로고    scopus 로고
    • Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathy
    • 21372210 10.1681/ASN.2010080869 1:CAS:528:DC%2BC3MXlslOjs7s%3D
    • Kohan DE, Pritchett Y, Molitch M, Wen S, Garimella T, Audhya P, Andress DL (2011) Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathy. J Am Soc Nephrol 22:763-772
    • (2011) J Am Soc Nephrol , vol.22 , pp. 763-772
    • Kohan, D.E.1    Pritchett, Y.2    Molitch, M.3    Wen, S.4    Garimella, T.5    Audhya, P.6    Andress, D.L.7
  • 72
    • 79954490055 scopus 로고    scopus 로고
    • Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone
    • 21270096 10.1152/ajprenal.00587.2010 1:CAS:528:DC%2BC3MXlt1Oktbc%3D
    • Wesson DE, Simoni J, Broglio K, Sheather S (2011) Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone. Am J Physiol Renal Physiol 300:F830-F837
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Wesson, D.E.1    Simoni, J.2    Broglio, K.3    Sheather, S.4
  • 73
    • 1842564170 scopus 로고    scopus 로고
    • Therapeutic potential for endothelin receptor antagonists in cardiovascular disorders
    • 14728028 10.2165/00129784-200101040-00007 1:CAS:528:DC%2BD38XitVGgsb4%3D
    • Spieker LE, Noll G, Luscher TF (2001) Therapeutic potential for endothelin receptor antagonists in cardiovascular disorders. Am J Cardiovasc Drugs 1:293-303
    • (2001) Am J Cardiovasc Drugs , vol.1 , pp. 293-303
    • Spieker, L.E.1    Noll, G.2    Luscher, T.F.3
  • 74
    • 67649859521 scopus 로고    scopus 로고
    • Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease
    • 19506099 10.1161/HYPERTENSIONAHA.109.132670 1:CAS:528: DC%2BD1MXntVyrtL0%3D
    • Dhaun N, Macintyre IM, Melville V, Lilitkarntakul P, Johnston NR, Goddard J, Webb DJ (2009) Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease. Hypertension 54:113-119
    • (2009) Hypertension , vol.54 , pp. 113-119
    • Dhaun, N.1    Macintyre, I.M.2    Melville, V.3    Lilitkarntakul, P.4    Johnston, N.R.5    Goddard, J.6    Webb, D.J.7
  • 75
    • 70349241843 scopus 로고    scopus 로고
    • Effects of endothelin receptor antagonism relate to the degree of renin-angiotensin system blockade in chronic proteinuric kidney disease
    • 19652085 10.1161/HYPERTENSIONAHA.109.138263 1:CAS:528: DC%2BD1MXhtV2gt7%2FM
    • Dhaun N, Macintyre IM, Melville V, Lilitkarntakul P, Johnston NR, Goddard J, Webb DJ (2009) Effects of endothelin receptor antagonism relate to the degree of renin-angiotensin system blockade in chronic proteinuric kidney disease. Hypertension 54:e19-e20
    • (2009) Hypertension , vol.54
    • Dhaun, N.1    Macintyre, I.M.2    Melville, V.3    Lilitkarntakul, P.4    Johnston, N.R.5    Goddard, J.6    Webb, D.J.7


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