-
1
-
-
17744388339
-
Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function
-
DOI 10.1210/en.141.9.3478
-
Udagawa N, Takahashi N, Yasuda H, et al. Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function. Endocrinology. 2000;141(9):3478-3484. (Pubitemid 32269038)
-
(2000)
Endocrinology
, vol.141
, Issue.9
, pp. 3478-3484
-
-
Udagawa, N.1
Takahashi, N.2
Yasuda, H.3
Mizuno, A.4
Itoh, K.5
Ueno, Y.6
Shinki, T.7
Gillespie, M.T.8
Martin, T.J.9
Higashio, K.10
Suda, T.11
-
2
-
-
0033888977
-
Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo
-
Lacey DL, Tan HL, Lu J, et al. Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. Am J Pathol. 2000;157(2):435-448.
-
(2000)
Am J Pathol
, vol.157
, Issue.2
, pp. 435-448
-
-
Lacey, D.L.1
Tan, H.L.2
Lu, J.3
-
4
-
-
37149016951
-
Myeloma cells and bone marrow osteoblast interactions: Role in the development of osteolytic lesions in multiple myeloma
-
Giuliani N, Rizzoli V. Myeloma cells and bone marrow osteoblast interactions: role in the development of osteolytic lesions in multiple myeloma. Leuk Lymphoma. 2007;48(12):2323-2329.
-
(2007)
Leuk Lymphoma
, vol.48
, Issue.12
, pp. 2323-2329
-
-
Giuliani, N.1
Rizzoli, V.2
-
5
-
-
38749106994
-
RANK ligand as a therapeutic target for bone metastases and multiple myeloma
-
Roodman GD, Dougall WC. RANK ligand as a therapeutic target for bone metastases and multiple myeloma. Cancer Treat Rev. 2008;34(1):92-101.
-
(2008)
Cancer Treat Rev
, vol.34
, Issue.1
, pp. 92-101
-
-
Roodman, G.D.1
Dougall, W.C.2
-
6
-
-
0035048973
-
Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow
-
DOI 10.1038/86523
-
Feuerer M, Beckhove P, Bai L, et al. Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow. Nat Med. 2001;7(4):452-458. (Pubitemid 32298548)
-
(2001)
Nature Medicine
, vol.7
, Issue.4
, pp. 452-458
-
-
Feuerer, M.1
Beckhove, P.2
Bai, L.3
Solomayer, E.-F.4
Bastert, G.5
Diel, I.J.6
Pedain, C.7
Oberniedermayr, M.8
Schirrmacher, V.9
Umansky, V.10
-
7
-
-
0036316236
-
Bone marrow CD8 T cells are in different activation state than those in lymphoid periphery
-
DOI 10.1002/1521-4141(200207)32:7<1873::AID-IMMU1873>3.0.CO;2-P
-
Di Rosa F, Santoni A. Bone marrow CD8 T cells are in a different activation state than those in lymphoid periphery. Eur J Immunol. 2002;32(7):1873-1880. (Pubitemid 34814542)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.7
, pp. 1873-1880
-
-
Di Rosa, F.1
Santoni, A.2
-
8
-
-
0141796315
-
Bone marrow as a priming site for T-cell responses to blood-borne antigen
-
Feuerer M, Beckhove P, Garbi N, et al. Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nat Med. 2003;9(9):1151-1157.
-
(2003)
Nat Med
, vol.9
, Issue.9
, pp. 1151-1157
-
-
Feuerer, M.1
Beckhove, P.2
Garbi, N.3
-
9
-
-
8544281696
-
Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals
-
Zou L, Barnett B, Safah H, et al. Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals. Cancer Res. 2004;64(22):8451-8455.
-
(2004)
Cancer Res
, vol.64
, Issue.22
, pp. 8451-8455
-
-
Zou, L.1
Barnett, B.2
Safah, H.3
-
10
-
-
20144389307
-
Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors
-
Noonan K, Matsui W, Serafini P, et al. Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors. Cancer Res. 2005;65(5):2026-2034.
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 2026-2034
-
-
Noonan, K.1
Matsui, W.2
Serafini, P.3
-
11
-
-
33751531874
-
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
-
Serafini P, Meckel K, Kelso M, et al. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med. 2006;203(12):2691-2702.
-
(2006)
J Exp Med
, vol.203
, Issue.12
, pp. 2691-2702
-
-
Serafini, P.1
Meckel, K.2
Kelso, M.3
-
12
-
-
42649115767
-
TH17 cells in development: An updated view of their molecular identity and genetic programming
-
Dong C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol. 2008;8(5):337-348.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.5
, pp. 337-348
-
-
Dong, C.1
-
13
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6(11):1123-1132.
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
14
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol. 2007;8(9):967-974.
-
(2007)
Nat Immunol
, vol.8
, Issue.9
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
-
15
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441(7090):235-238.
-
(2006)
Nature
, vol.441
, Issue.7090
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
16
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T-cell subset that links T cell activation and bone destruction
-
Sato K, Suematsu A, Okamoto K, et al. Th17 functions as an osteoclastogenic helper T-cell subset that links T cell activation and bone destruction. J Exp Med. 2006;203(12):2673-2682.
-
(2006)
J Exp Med
, vol.203
, Issue.12
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
-
17
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence A, Tato CM, Davidson TS, et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity. 2007;26(3):371-381.
-
(2007)
Immunity
, vol.26
, Issue.3
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
-
18
-
-
0022338260
-
Monoclonal antibodies to osteoclastomas (giant cell bone tumors): Definition of osteoclast-specific cellular antigens
-
Horton MA, Lewis D, McNulty K, Pringle JA, Chambers TJ. Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer Res. 1985;45(11):5663-5669.
-
(1985)
Cancer Res
, vol.45
, Issue.11
, pp. 5663-5669
-
-
Horton, M.A.1
Lewis, D.2
McNulty, K.3
Pringle, J.A.4
Chambers, T.J.5
-
19
-
-
40449134510
-
High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients
-
Mylin AK, Abildgaard N, Johansen JS, et al. High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients. Eur J Haematol. 2008;80(4):310-317.
-
(2008)
Eur J Haematol
, vol.80
, Issue.4
, pp. 310-317
-
-
Mylin, A.K.1
Abildgaard, N.2
Johansen, J.S.3
-
20
-
-
0030305457
-
A language for data analysis and graphics
-
Ihaka R. A language for data analysis and graphics. J Comput Graphic Stat. 1996;5(5):299-314.
-
(1996)
J Comput Graphic Stat
, vol.5
, Issue.5
, pp. 299-314
-
-
Ihaka, R.1
-
21
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey V, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10)[R80]:1465-6914.
-
(2004)
Genome Biol
, vol.5
, Issue.10 R80
, pp. 1465-6914
-
-
Gentleman, R.C.1
Carey, V.2
Bates, D.M.3
-
22
-
-
5644258322
-
c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells
-
Zou W, Liu X, Yue P, et al. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. Cancer Res. 2004;64(20):7570-7578.
-
(2004)
Cancer Res
, vol.64
, Issue.20
, pp. 7570-7578
-
-
Zou, W.1
Liu, X.2
Yue, P.3
-
23
-
-
0024419152
-
Production of cytokines by bone marrow cells obtained from patients with multiple myeloma
-
Lichtenstein A, Berenson J, Norman D, Chang MP, Carlile A. Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood. 1989;74(4):1266-1273. (Pubitemid 19227434)
-
(1989)
Blood
, vol.74
, Issue.4
, pp. 1266-1273
-
-
Lichtenstein, A.1
Berenson, J.2
Norman, D.3
Chang, M.-P.4
Carlile, A.5
-
24
-
-
43149089554
-
The pathogenesis of the bone disease of multiple myeloma
-
Edwards CM, Zhuang J, Mundy GR. The pathogenesis of the bone disease of multiple myeloma. Bone. 2008;42(6):1007-1013.
-
(2008)
Bone
, vol.42
, Issue.6
, pp. 1007-1013
-
-
Edwards, C.M.1
Zhuang, J.2
Mundy, G.R.3
-
25
-
-
57449112782
-
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells
-
Korn T, Mitsdoerffer M, Croxford AL, et al. IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2008;105(47):18460-18465.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.47
, pp. 18460-18465
-
-
Korn, T.1
Mitsdoerffer, M.2
Croxford, A.L.3
-
26
-
-
0035383761
-
Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand
-
Han JH, Choi SJ, Kurihara N, Koide M, Oba Y, Roodman GD. Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood. 2001;97(11):3349-3353.
-
(2001)
Blood
, vol.97
, Issue.11
, pp. 3349-3353
-
-
Han, J.H.1
Choi, S.J.2
Kurihara, N.3
Koide, M.4
Oba, Y.5
Roodman, G.D.6
-
27
-
-
33645959483
-
STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice
-
Cho ML, Kang JW, Moon YM, et al. STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J Immunol. 2006;176(9):5652-5661.
-
(2006)
J Immunol
, vol.176
, Issue.9
, pp. 5652-5661
-
-
Cho, M.L.1
Kang, J.W.2
Moon, Y.M.3
-
28
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006;24(2):179-189.
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
29
-
-
40849141379
-
CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation
-
Atanackovic D, Cao Y, Luetkens T, et al. CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation. Haematologica. 2008;93(3):423-430.
-
(2008)
Haematologica
, vol.93
, Issue.3
, pp. 423-430
-
-
Atanackovic, D.1
Cao, Y.2
Luetkens, T.3
-
30
-
-
0020960066
-
Direct bone resorbing activity of murine myeloma cells
-
McDonald DF, Schofield BH, Prezioso EM, et al. Direct bone resorbing activity of murine myeloma cells. Cancer Lett. 1983;19(2):119-124.
-
(1983)
Cancer Lett
, vol.19
, Issue.2
, pp. 119-124
-
-
McDonald, D.F.1
Schofield, B.H.2
Prezioso, E.M.3
-
31
-
-
33846201640
-
Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: A new type of cancer-host partnership?
-
Andersen TL, Boissy P, Sondergaard TE, et al. Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: a new type of cancer-host partnership? J Pathol. 2007;211(1):10-17.
-
(2007)
J Pathol
, vol.211
, Issue.1
, pp. 10-17
-
-
Andersen, T.L.1
Boissy, P.2
Sondergaard, T.E.3
-
32
-
-
33745494534
-
A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: A potential role in the development of lytic bone disease and tumor progression in multiple myeloma
-
Gunn WG, Conley A, Deininger L, Olson SD, Prockop DJ, Gregory CA. A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. Stem Cells. 2006;24(4):986-991.
-
(2006)
Stem Cells
, vol.24
, Issue.4
, pp. 986-991
-
-
Gunn, W.G.1
Conley, A.2
Deininger, L.3
Olson, S.D.4
Prockop, D.J.5
Gregory, C.A.6
-
33
-
-
0037114636
-
Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: A potential role in multiple myeloma bone disease
-
Giuliani N, Colla S, Sala R, et al. Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: a potential role in multiple myeloma bone disease. Blood. 2002;100(13):4615-4621.
-
(2002)
Blood
, vol.100
, Issue.13
, pp. 4615-4621
-
-
Giuliani, N.1
Colla, S.2
Sala, R.3
-
34
-
-
69249092613
-
A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity
-
Huber M, Heink S, Grothe H, et al. A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity. Eur J Immunol. 2009;39(7):1716-1725.
-
(2009)
Eur J Immunol
, vol.39
, Issue.7
, pp. 1716-1725
-
-
Huber, M.1
Heink, S.2
Grothe, H.3
-
35
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing K, Onishi Y, Prieto-Martin P, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science. 2008;322(5899):271-275.
-
(2008)
Science
, vol.322
, Issue.5899
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
-
36
-
-
47249103596
-
CTLA-4 directly inhibits osteoclast formation
-
Axmann R, Herman S, Zaiss M, et al. CTLA-4 directly inhibits osteoclast formation. Ann Rheum Dis. 2008;67(11):1603-1609.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.11
, pp. 1603-1609
-
-
Axmann, R.1
Herman, S.2
Zaiss, M.3
-
37
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
Yang XO, Panopoulos AD, Nurieva R, et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem. 2007;282(13):9358-9363.
-
(2007)
J Biol Chem
, vol.282
, Issue.13
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
-
38
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 2006;126(6):1121-1133.
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
39
-
-
37749021324
-
Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity
-
Harris TJ, Grosso JF, Yen HR, et al. Cutting edge: an in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol. 2007;179(7):4313-4317.
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4313-4317
-
-
Harris, T.J.1
Grosso, J.F.2
Yen, H.R.3
-
40
-
-
33646383590
-
Recent advances in understanding the mechanism of action of bisphosphonates
-
Coxon FP, Thompson K, Rogers MJ. Recent advances in understanding the mechanism of action of bisphosphonates. Curr Opin Pharmacol. 2006;6(3):307-312.
-
(2006)
Curr Opin Pharmacol
, vol.6
, Issue.3
, pp. 307-312
-
-
Coxon, F.P.1
Thompson, K.2
Rogers, M.J.3
-
41
-
-
15244344110
-
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
-
DOI 10.1016/j.immuni.2005.01.011
-
Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity. 2005;22(3):285-294. (Pubitemid 40387471)
-
(2005)
Immunity
, vol.22
, Issue.3
, pp. 285-294
-
-
Stark, M.A.1
Huo, Y.2
Burcin, T.L.3
Morris, M.A.4
Olson, T.S.5
Ley, K.6
-
42
-
-
54049156803
-
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
-
Breitkreutz I, Raab MS, Vallet S, et al. Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma. Leukemia. 2008;22(10):1925-1932.
-
(2008)
Leukemia
, vol.22
, Issue.10
, pp. 1925-1932
-
-
Breitkreutz, I.1
Raab, M.S.2
Vallet, S.3
|