-
1
-
-
0034575124
-
Apolipoprotein E. Far more than a lipid transport protein
-
Mahley, R. W., and Rall, S. C., Jr. (2000) Apolipoprotein E. Far more than a lipid transport protein. Annu. Rev. Genomics Hum. Genet. 1, 507-537
-
(2000)
Annu. Rev. Genomics Hum. Genet.
, vol.1
, pp. 507-537
-
-
Mahley, R.W.1
Rall Jr., S.C.2
-
2
-
-
0024299370
-
Apolipoprotein E. Cholesterol transport protein with expanding role in cell biology
-
Mahley, R. W. (1988) Apolipoprotein E. Cholesterol transport protein with expanding role in cell biology. Science 240, 622-630
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
3
-
-
67349270965
-
Apolipoprotein E and its receptors in Alzheimer's disease. Pathways, pathogenesis, and therapy
-
Bu, G. (2009) Apolipoprotein E and its receptors in Alzheimer's disease. Pathways, pathogenesis, and therapy. Nat. Rev. Neurosci. 10, 333-344
-
(2009)
Nat. Rev. Neurosci.
, vol.10
, pp. 333-344
-
-
Bu, G.1
-
4
-
-
84873722367
-
Apolipoprotein E and Alzheimer disease. Risk, mechanisms, and therapy
-
Liu, C.-C, Liu, C.-C, Kanekiyo, T., Xu, H., and Bu, G. (2013) Apolipoprotein E and Alzheimer disease. Risk, mechanisms, and therapy. Nat. Rev. Neurol. 9, 106-118
-
(2013)
Nat. Rev. Neurol.
, vol.9
, pp. 106-118
-
-
Liu, C.-C.1
Liu, C.-C.2
Kanekiyo, T.3
Xu, H.4
Bu, G.5
-
5
-
-
0028303072
-
Apolipoprotein E. Structure-function relationships
-
Weisgraber, K. H. (1994) Apolipoprotein E. Structure-function relationships. Adv. Protein Chem. 45, 249-302
-
(1994)
Adv. Protein Chem.
, vol.45
, pp. 249-302
-
-
Weisgraber, K.H.1
-
6
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer, L. A., Cupples, L. A., Haines, J. L., Hyman, B., Kukull, W. A., Mayeux, R., Myers, R. H., Pericak-Vance, M. A., Risch, N., and Van Duijn, C. M. (1997) Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278, 1349-1356
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
7
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C, Small, G. W., Roses, A. D., Haines, J. L., and Pericak-Vance, M. A. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
8
-
-
0027374047
-
Apolipoprotein E in sporadic Alzheimer's disease. Allelic variation and receptor interactions
-
Rebeck, G. W., Reiter, J. S., Strickland, D. K., and Hyman, B. T. (1993) Apolipoprotein E in sporadic Alzheimer's disease. Allelic variation and receptor interactions. Neuron 11, 575-580
-
(1993)
Neuron
, vol.11
, pp. 575-580
-
-
Rebeck, G.W.1
Reiter, J.S.2
Strickland, D.K.3
Hyman, B.T.4
-
9
-
-
0027973579
-
Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E e4 allele
-
Reed, T., Carmelli, D., Swan, G. E., Breitner, J. C, Welsh, K. A., Jarvik, G. P., Deeb, S., and Auwerx, J. (1994) Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E e4 allele. Arch. Neurol. 51, 1189-1192
-
(1994)
Arch. Neurol.
, vol.51
, pp. 1189-1192
-
-
Reed, T.1
Carmelli, D.2
Swan, G.E.3
Breitner, J.C.4
Welsh, K.A.5
Jarvik, G.P.6
Deeb, S.7
Auwerx, J.8
-
10
-
-
84555187600
-
Apolipoprotein E-e4, processing speed, and white matter volume in a genetically enriched sample of midlife adults
-
Ready, R. E., Baran, B., Chaudhry, M., Schatz, K., Gordon, J., and Spencer, R. M. (2011) Apolipoprotein E-e4, processing speed, and white matter volume in a genetically enriched sample of midlife adults. Am. J. Alzheimers Dis. Other Demen. 26, 463-468
-
(2011)
Am. J. Alzheimers Dis. Other Demen.
, vol.26
, pp. 463-468
-
-
Ready, R.E.1
Baran, B.2
Chaudhry, M.3
Schatz, K.4
Gordon, J.5
Spencer, R.M.6
-
11
-
-
34548543513
-
Predicting memory decline in normal elderly. Genetics, MRI, and cognitive reserve
-
Tupler, L. A., Krishnan, K. R., Greenberg, D. L., Marcovina, S. M., Payne, M. E., MacFall, J. R., Charles, H. C, and Doraiswamy, P. M. (2007) Predicting memory decline in normal elderly. Genetics, MRI, and cognitive reserve. Neurobiol. Aging 28, 1644-1656
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1644-1656
-
-
Tupler, L.A.1
Krishnan, K.R.2
Greenberg, D.L.3
Marcovina, S.M.4
Payne, M.E.5
MacFall, J.R.6
Charles, H.C.7
Doraiswamy, P.M.8
-
12
-
-
0034974216
-
Memory performance in healthy elderly without Alzheimer's disease. Effects of time and apolipoprotein-E
-
Mayeux, R., Small, S. A., Tang, M., Tycko, B., and Stern, Y. (2001) Memory performance in healthy elderly without Alzheimer's disease. Effects of time and apolipoprotein-E. Neurobiol. Aging 22, 683-689
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 683-689
-
-
Mayeux, R.1
Small, S.A.2
Tang, M.3
Tycko, B.4
Stern, Y.5
-
13
-
-
79955451703
-
The apolipoprotein E antagonistic pleiotropy hypothesis. Review and recommendations
-
Tuminello, E. R., and Han, S. D. (2011) The apolipoprotein E antagonistic pleiotropy hypothesis. Review and recommendations. Int. J. Alzheimers Dis. 2011, 726197
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 726197
-
-
Tuminello, E.R.1
Han, S.D.2
-
14
-
-
0025171570
-
Apolipoprotein E distribution among human plasma lipoproteins. Role of the cysteine-arginine interchange at residue 112
-
Weisgraber, K. H. (1990) Apolipoprotein E distribution among human plasma lipoproteins. Role of the cysteine-arginine interchange at residue 112. J. Lipid Res. 31, 1503-1511
-
(1990)
J. Lipid Res.
, vol.31
, pp. 1503-1511
-
-
Weisgraber, K.H.1
-
15
-
-
0029766916
-
Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
-
Dong, L.-M., and Weisgraber, K. H. (1996) Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins. J. Biol. Chem. 271, 19053-19057
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19053-19057
-
-
Dong, L.-M.1
Weisgraber, K.H.2
-
16
-
-
58149251844
-
Impact of apolipoprotein E (ApoE) polymorphism on brain apoE Levels
-
Riddell, D. R., Zhou, H., Atchison, K., Warwick, H. K., Atkinson, P. J., Jefferson, J., Xu, L., Aschmies, S., Kirksey, Y., Hu, Y., Wagner, E., Parratt, A., Xu, J., Li, Z., Zaleska, M. M., Jacobsen, J. S., Pangalos, M. N., and Reinhart, P. H. (2008) Impact of apolipoprotein E (ApoE) polymorphism on brain apoE Levels. J. Neurosci. 28, 11445-11453
-
(2008)
J. Neurosci.
, vol.28
, pp. 11445-11453
-
-
Riddell, D.R.1
Zhou, H.2
Atchison, K.3
Warwick, H.K.4
Atkinson, P.J.5
Jefferson, J.6
Xu, L.7
Aschmies, S.8
Kirksey, Y.9
Hu, Y.10
Wagner, E.11
Parratt, A.12
Xu, J.13
Li, Z.14
Zaleska, M.M.15
Jacobsen, J.S.16
Pangalos, M.N.17
Reinhart, P.H.18
-
17
-
-
0035949490
-
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E
-
Raffaï, R. L., Dong, L.-M., Farese, R. V., Jr., and Weisgraber, K. H. (2001) Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E. Proc. Natl. Acad. Sci. 98, 11587-11591
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 11587-11591
-
-
Raffaï, R.L.1
Dong, L.-M.2
Farese Jr., R.V.3
Weisgraber, K.H.4
-
18
-
-
43649084798
-
Apolipoprotein E4 domain interaction. Synaptic and cognitive deficits in mice
-
Zhong, N., Scearce-Levie, K., Ramaswamy, G., and Weisgraber, K. H. (2008) Apolipoprotein E4 domain interaction. Synaptic and cognitive deficits in mice. Alzheimers Dement. 4, 179-192
-
(2008)
Alzheimers Dement.
, vol.4
, pp. 179-192
-
-
Zhong, N.1
Scearce-Levie, K.2
Ramaswamy, G.3
Weisgraber, K.H.4
-
19
-
-
34248659126
-
Two-day radial-arm water maze learning and memory task. Robust resolution of amyloid-related memory deficits in transgenic mice
-
Alamed, J., Wilcock, D. M., Diamond, D. M., Gordon, M. N., and Morgan, D. (2006) Two-day radial-arm water maze learning and memory task. Robust resolution of amyloid-related memory deficits in transgenic mice. Nat Protoc. 1, 1671-1679
-
(2006)
Nat Protoc.
, vol.1
, pp. 1671-1679
-
-
Alamed, J.1
Wilcock, D.M.2
Diamond, D.M.3
Gordon, M.N.4
Morgan, D.5
-
20
-
-
0026660230
-
A two-trial memory task with automated recording. Study in young and aged rats
-
Dellu, F., Mayo, W., Cherkaoui, J., Le Moal, M., and Simon, H. (1992) A two-trial memory task with automated recording. Study in young and aged rats. Brain Res. 588, 132-139
-
(1992)
Brain Res.
, vol.588
, pp. 132-139
-
-
Dellu, F.1
Mayo, W.2
Cherkaoui, J.3
Le Moal, M.4
Simon, H.5
-
21
-
-
79960015625
-
Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency
-
Vuillermot, S., Joodmardi, E., Perlmann, T., Ove Ögren, S., Feldon, J., and Meyer, U. (2011) Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency. Genes Brain Behav. 10, 589-603
-
(2011)
Genes Brain Behav.
, vol.10
, pp. 589-603
-
-
Vuillermot, S.1
Joodmardi, E.2
Perlmann, T.3
Ove Ögren, S.4
Feldon, J.5
Meyer, U.6
-
22
-
-
22144436260
-
Chronic stress leaves noveltyseeking behavior intact while impairing spatial recognition memory in the Y-maze
-
Wright, R. L., and Conrad, C. D. (2005) Chronic stress leaves noveltyseeking behavior intact while impairing spatial recognition memory in the Y-maze. Stress 8, 151-154
-
(2005)
Stress
, vol.8
, pp. 151-154
-
-
Wright, R.L.1
Conrad, C.D.2
-
23
-
-
34447292290
-
Neuropharmacological effects of oleamide in male and female mice
-
Akanmu, M. A., Adeosun, S. O., and Ilesanmi, O. R. (2007) Neuropharmacological effects of oleamide in male and female mice. Behav. Brain Res. 182, 88-94
-
(2007)
Behav. Brain Res.
, vol.182
, pp. 88-94
-
-
Akanmu, M.A.1
Adeosun, S.O.2
Ilesanmi, O.R.3
-
24
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations. Lack of association with amyloid deposits
-
Holcomb, L. A., Gordon, M. N., Jantzen, P., Hsiao, K., Duff, K., and Morgan, D. (1999) Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations. Lack of association with amyloid deposits. Behav. Genet. 29, 177-185
-
(1999)
Behav. Genet.
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsiao, K.4
Duff, K.5
Morgan, D.6
-
25
-
-
79953758383
-
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
-
Ramonet, D., Daher, J. P., Lin, B. M., Stafa, K., Kim, J., Banerjee, R., Westerlund, M., Pletnikova, O., Glauser, L., Yang, L., Liu, Y., Swing, D. A., Beal, M. F., Troncoso, J. C, McCaffery, J. M., Jenkins, N. A., Copeland, N. G., Galter, D., Thomas, B., Lee, M. K., Dawson, T. M., Dawson, V. L., and Moore, D. J. (2011) Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS ONE 6, e18568
-
(2011)
PLoS ONE
, vol.6
-
-
Ramonet, D.1
Daher, J.P.2
Lin, B.M.3
Stafa, K.4
Kim, J.5
Banerjee, R.6
Westerlund, M.7
Pletnikova, O.8
Glauser, L.9
Yang, L.10
Liu, Y.11
Swing, D.A.12
Beal, M.F.13
Troncoso, J.C.14
McCaffery, J.M.15
Jenkins, N.A.16
Copeland, N.G.17
Galter, D.18
Thomas, B.19
Lee, M.K.20
Dawson, T.M.21
Dawson, V.L.22
Moore, D.J.23
more..
-
26
-
-
84870487990
-
Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease
-
Adeosun, S. O., Hou, X., Jiao, Y., Zheng, B., Henry, S., Hill, R., He, Z., Pani, A., Kyle, P., Ou, X., Mosley, T., Farley, J. M., Stockmeier, C, Paul, I., Bigler, S., Brinton, R. D., Smeyne, R., and Wang, J. M. (2012) Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease. PLoS ONE 7, e50040
-
(2012)
PLoS ONE
, vol.7
-
-
Adeosun, S.O.1
Hou, X.2
Jiao, Y.3
Zheng, B.4
Henry, S.5
Hill, R.6
He, Z.7
Pani, A.8
Kyle, P.9
Ou, X.10
Mosley, T.11
Farley, J.M.12
Stockmeier, C.13
Paul, I.14
Bigler, S.15
Brinton, R.D.16
Smeyne, R.17
Wang, J.M.18
-
27
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2-AACT method
-
Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-AACT method. Methods 25, 402-408
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
28
-
-
33846052176
-
QPrimerDepot. A primer database for quantitative real time PCR
-
Cui, W., Taub, D. D., and Gardner, K. (2007) qPrimerDepot. A primer database for quantitative real time PCR. Nucleic Acids Res. 35, D805-D809
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Cui, W.1
Taub, D.D.2
Gardner, K.3
-
29
-
-
0032517795
-
Quantitative analysis of GABAergic neurons in the mouse hippocampus, with optical dissector using confocal laser scanning microscope
-
Jinno, S., Aika, Y., Fukuda, T., and Kosaka, T. (1998) Quantitative analysis of GABAergic neurons in the mouse hippocampus, with optical dissector using confocal laser scanning microscope. Brain Res. 814, 55-70
-
(1998)
Brain Res.
, vol.814
, pp. 55-70
-
-
Jinno, S.1
Aika, Y.2
Fukuda, T.3
Kosaka, T.4
-
30
-
-
80052517958
-
Stereologic estimation of hippocampal GluR2β- and calretinin-immunoreactive hilar neurons (presumptive mossy cells) in two mouse models of temporal lobe epilepsy
-
Volz, F., Bock, H. H, Gierthmuehlen, M., Zentner, J., Haas, C. A., and Freiman, T. M. (2011) Stereologic estimation of hippocampal GluR2β- and calretinin-immunoreactive hilar neurons (presumptive mossy cells) in two mouse models of temporal lobe epilepsy. Epilepsia 52, 1579-1589
-
(2011)
Epilepsia
, vol.52
, pp. 1579-1589
-
-
Volz, F.1
Bock, H.H.2
Gierthmuehlen, M.3
Zentner, J.4
Haas, C.A.5
Freiman, T.M.6
-
31
-
-
33845235682
-
Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation
-
Plümpe, T., Ehninger, D., Steiner, B., Klempin, F., Jessberger, S., Brandt, M., Römer, B., Rodriguez, G. R., Kronenberg, G., and Kempermann, G. (2006) Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation. BMC Neurosci. 7, 77
-
(2006)
BMC Neurosci.
, vol.7
, pp. 77
-
-
Plümpe, T.1
Ehninger, D.2
Steiner, B.3
Klempin, F.4
Jessberger, S.5
Brandt, M.6
Römer, B.7
Rodriguez, G.R.8
Kronenberg, G.9
Kempermann, G.10
-
32
-
-
84871742808
-
Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice
-
Leung, L., Andrews-Zwilling, Y., Yoon, S. Y., Jain, S., Ring, K., Dai, J., Wang, M. M., Tong, L., Walker, D., and Huang, Y. (2012) Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice. PLoS ONE 7, e53569
-
(2012)
PLoS ONE
, vol.7
-
-
Leung, L.1
Andrews-Zwilling, Y.2
Yoon, S.Y.3
Jain, S.4
Ring, K.5
Dai, J.6
Wang, M.M.7
Tong, L.8
Walker, D.9
Huang, Y.10
-
33
-
-
84873095084
-
Enhanced dendritogenesis and axogenesis in hippocampal neuroblasts of LRRK2 knockout mice
-
Paus, M., Kohl, Z., Ben Abdallah, N. M., Galter, D., Gillardon, F., and Winkler, J. (2013) Enhanced dendritogenesis and axogenesis in hippocampal neuroblasts of LRRK2 knockout mice. Brain Res. 1497, 85-100
-
(2013)
Brain Res.
, vol.1497
, pp. 85-100
-
-
Paus, M.1
Kohl, Z.2
Ben Abdallah, N.M.3
Galter, D.4
Gillardon, F.5
Winkler, J.6
-
34
-
-
14844310369
-
Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats
-
Scharfman, H, Goodman, J., Macleod, A., Phani, S., Antonelli, C, and Croll, S. (2005) Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp. Neurol. 192, 348-356
-
(2005)
Exp. Neurol.
, vol.192
, pp. 348-356
-
-
Scharfman, H.1
Goodman, J.2
Macleod, A.3
Phani, S.4
Antonelli, C.5
Croll, S.6
-
35
-
-
84867266696
-
BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission
-
Waterhouse, E. G., An, J. J., Orefice, L. L., Baydyuk, M., Liao, G.-Y., Zheng, K., Lu, B., and Xu, B. (2012) BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission. J. Neurosci. 32, 14318-14330
-
(2012)
J. Neurosci.
, vol.32
, pp. 14318-14330
-
-
Waterhouse, E.G.1
An, J.J.2
Orefice, L.L.3
Baydyuk, M.4
Liao, G.-Y.5
Zheng, K.6
Lu, B.7
Xu, B.8
-
36
-
-
70449523361
-
Early age-related changes in adult hippocampal neurogenesis in C57 mice
-
Ben Abdallah, N. M., Slomianka, L., Vyssotski, A. L., and Lipp, H.-P. (2010) Early age-related changes in adult hippocampal neurogenesis in C57 mice. Neurobiol. Aging 31, 151-161
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 151-161
-
-
Ben Abdallah, N.M.1
Slomianka, L.2
Vyssotski, A.L.3
Lipp, H.-P.4
-
37
-
-
33847258237
-
Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
-
Zhang, C., McNeil, E., Dressler, L., and Siman, R. (2007) Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp. Neurol. 204, 77-87
-
(2007)
Exp. Neurol.
, vol.204
, pp. 77-87
-
-
Zhang, C.1
McNeil, E.2
Dressler, L.3
Siman, R.4
-
38
-
-
79955483247
-
Limited hippocampal neurogenesis in SAMP8 mouse model of Alzheimer's disease
-
Gang, B., Yue, C., Han, N, Xue, H., Li, B., Sun, L., Li, X., and Zhao, Q. (2011) Limited hippocampal neurogenesis in SAMP8 mouse model of Alzheimer's disease. Brain Res. 1389, 183-193
-
(2011)
Brain Res.
, vol.1389
, pp. 183-193
-
-
Gang, B.1
Yue, C.2
Han, N.3
Xue, H.4
Li, B.5
Sun, L.6
Li, X.7
Zhao, Q.8
-
39
-
-
34447648402
-
Differences in doublecortin immunoreactivity and protein levels in the hippocampal dentate gyrus between adult and aged dogs
-
Hwang, I. K., Yoo, K.-Y., Li, H, Choi, J. H, Kwon, Y.-G., Ahn, Y., Lee, I. S., and Won, M. H. (2007) Differences in doublecortin immunoreactivity and protein levels in the hippocampal dentate gyrus between adult and aged dogs. Neurochem. Res. 32, 1604-1609
-
(2007)
Neurochem. Res.
, vol.32
, pp. 1604-1609
-
-
Hwang, I.K.1
Yoo, K.-Y.2
Li, H.3
Choi, J.H.4
Kwon, Y.-G.5
Ahn, Y.6
Lee, I.S.7
Won, M.H.8
-
40
-
-
4444269849
-
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw, Ind) mice
-
Jin, K., Galvan, V., Xie, L., Mao, X. O., Gorostiza, O. F., Bredesen, D. E., and Greenberg, D. A. (2004) Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw, Ind) mice. Proc. Natl. Acad. Sci. U. S. A. 101, 13363-13367
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13363-13367
-
-
Jin, K.1
Galvan, V.2
Xie, L.3
Mao, X.O.4
Gorostiza, O.F.5
Bredesen, D.E.6
Greenberg, D.A.7
-
41
-
-
48949099311
-
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
-
Bour, A., Grootendorst, J., Vogel, E., Kelche, C., Dodart, J.-C., Bales, K., Moreau, P.-H, Sullivan, P. M., and Mathis, C. (2008) Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks. Behav. Brain Res. 193, 174-182
-
(2008)
Behav. Brain Res.
, vol.193
, pp. 174-182
-
-
Bour, A.1
Grootendorst, J.2
Vogel, E.3
Kelche, C.4
Dodart, J.-C.5
Bales, K.6
Moreau, P.-H.7
Sullivan, P.M.8
Mathis, C.9
-
42
-
-
0034870449
-
Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice. ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology
-
Hartman, R. E., Wozniak, D. F., Nardi, A., Olney, J. W., Sartorius, L., and Holtzman, D. M. (2001) Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice. ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology. Exp. Neurol. 170, 326-344
-
(2001)
Exp. Neurol.
, vol.170
, pp. 326-344
-
-
Hartman, R.E.1
Wozniak, D.F.2
Nardi, A.3
Olney, J.W.4
Sartorius, L.5
Holtzman, D.M.6
-
43
-
-
0035066332
-
Alzheimer's disease. Genes, proteins, and therapy
-
Selkoe, D. J. (2001) Alzheimer's disease. Genes, proteins, and therapy. Physiol. Rev. 81, 741-766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
44
-
-
84865598830
-
Adultborn hippocampal neurons promote cognitive flexibility in mice
-
Burghardt, N. S., Park, E. H., Hen, R., and Fenton, A. A. (2012) Adultborn hippocampal neurons promote cognitive flexibility in mice. Hippocampus 22, 1795-1808
-
(2012)
Hippocampus
, vol.22
, pp. 1795-1808
-
-
Burghardt, N.S.1
Park, E.H.2
Hen, R.3
Fenton, A.A.4
-
45
-
-
0028169648
-
Reduced apolipoprotein e4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals
-
Rebeck, G. W., Perls, T. T., West, H. L., Sodhi, P., Lipsitz, L. A., and Hyman, B. T. (1994) Reduced apolipoprotein e4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals. Neurology 44, 1513-1516
-
(1994)
Neurology
, vol.44
, pp. 1513-1516
-
-
Rebeck, G.W.1
Perls, T.T.2
West, H.L.3
Sodhi, P.4
Lipsitz, L.A.5
Hyman, B.T.6
-
46
-
-
0029886560
-
Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition
-
Corder, E. H., Lannfelt, L., Viitanen, M., Corder, L. S., Manton, K. G., Winblad, B., and Basun, H. (1996) Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. Arch. Neurol. 53, 418-422
-
(1996)
Arch. Neurol.
, vol.53
, pp. 418-422
-
-
Corder, E.H.1
Lannfelt, L.2
Viitanen, M.3
Corder, L.S.4
Manton, K.G.5
Winblad, B.6
Basun, H.7
-
47
-
-
58749102624
-
The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80
-
Negash, S., Greenwood, P. M., Sunderland, T., Parasuraman, R., Geda, Y. E., Knopman, D. S., Boeve, B. F., Ivnik, R. J., Petersen, R. C., and Smith, G. E. (2009) The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80. Neuropsychology 23, 81-89
-
(2009)
Neuropsychology
, vol.23
, pp. 81-89
-
-
Negash, S.1
Greenwood, P.M.2
Sunderland, T.3
Parasuraman, R.4
Geda, Y.E.5
Knopman, D.S.6
Boeve, B.F.7
Ivnik, R.J.8
Petersen, R.C.9
Smith, G.E.10
-
48
-
-
84867797446
-
Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide
-
Hashimoto, T., Serrano-Pozo, A., Hori, Y., Adams, K. W., Takeda, S., Banerji, A. O., Mitani, A., Joyner, D., Thyssen, D. H., Bacskai, B. J., Frosch, M. P., Spires-Jones, T. L., Finn, M. B., Holtzman, D. M., and Hyman, B. T. (2012) Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide. J. Neurosci. 32, 15181-15192
-
(2012)
J. Neurosci.
, vol.32
, pp. 15181-15192
-
-
Hashimoto, T.1
Serrano-Pozo, A.2
Hori, Y.3
Adams, K.W.4
Takeda, S.5
Banerji, A.O.6
Mitani, A.7
Joyner, D.8
Thyssen, D.H.9
Bacskai, B.J.10
Frosch, M.P.11
Spires-Jones, T.L.12
Finn, M.B.13
Holtzman, D.M.14
Hyman, B.T.15
-
49
-
-
79955663093
-
High ability of apolipoprotein E4to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease
-
Cerf, E., Gustot, A., Goormaghtigh, E., Ruysschaert, J.-M., and Raussens, V. (2011) High ability of apolipoprotein E4to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease. FASEBJ. 25, 1585-1595
-
(2011)
FASEBJ
, vol.25
, pp. 1585-1595
-
-
Cerf, E.1
Gustot, A.2
Goormaghtigh, E.3
Ruysschaert, J.-M.4
Raussens, V.5
-
50
-
-
0027365822
-
Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
-
Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H, Pericak-Vance, M. A., Goldgaber, D., and Roses, A. D. (1993) Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. 90, 9649-9653
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.J.4
Hulette, C.M.5
Joo, S.H.6
Pericak-Vance, M.A.7
Goldgaber, D.8
Roses, A.D.9
-
51
-
-
0036233168
-
Human and murine apoE markedly alters Aβ metabolism before and after plaque formation in a mouse model of Alzheimer's disease
-
Fagan, A. M., Watson, M., Parsadanian, M., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2002) Human and murine apoE markedly alters Aβ metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 9, 305-318
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 305-318
-
-
Fagan, A.M.1
Watson, M.2
Parsadanian, M.3
Bales, K.R.4
Paul, S.M.5
Holtzman, D.M.6
-
52
-
-
0033532373
-
Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures
-
Beffert, U., Aumont, N, Dea, D., Lussier-Cacan, S., Davignon, J., and Poirier, J. (1999) Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures. Mol. Brain Res. 68, 181-185
-
(1999)
Mol. Brain Res.
, vol.68
, pp. 181-185
-
-
Beffert, U.1
Aumont, N.2
Dea, D.3
Lussier-Cacan, S.4
Davignon, J.5
Poirier, J.6
-
53
-
-
12844273475
-
Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's disease
-
Dodart, J.-C., Marr, R. A., Koistinaho, M., Gregersen, B. M., Malkani, S., Verma, I. M., and Paul, S. M. (2005) Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 102, 1211-1216
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 1211-1216
-
-
Dodart, J.-C.1
Marr, R.A.2
Koistinaho, M.3
Gregersen, B.M.4
Malkani, S.5
Verma, I.M.6
Paul, S.M.7
-
54
-
-
0345171818
-
Apolipoprotein E and β-amyloid (1-42) regulation of glycogen synthase kinase-3β
-
Cedazo-Mínguez, A., Popescu, B. O., Blanco-Millán, J. M., Akterin, S., Pei, J.-J., Winblad, B., and Cowburn, R. F. (2003) Apolipoprotein E and β-amyloid (1-42) regulation of glycogen synthase kinase-3β. J. Neurochem. 87, 1152-1164
-
(2003)
J. Neurochem.
, vol.87
, pp. 1152-1164
-
-
Cedazo-Mínguez, A.1
Popescu, B.O.2
Blanco-Millán, J.M.3
Akterin, S.4
Pei, J.-J.5
Winblad, B.6
Cowburn, R.F.7
-
55
-
-
0034711453
-
Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3β identified by nano-electrospray mass spectrometry
-
Gibb, G. M., Pearce, J., Betts, J. C, Lovestone, S., Hoffmann, M. M., Maerz, W., Blackstock, W. P., and Anderton, B. H. (2000) Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3β identified by nano-electrospray mass spectrometry. FEBS Lett. 485, 99-103
-
(2000)
FEBS Lett.
, vol.485
, pp. 99-103
-
-
Gibb, G.M.1
Pearce, J.2
Betts, J.C.3
Lovestone, S.4
Hoffmann, M.M.5
Maerz, W.6
Blackstock, W.P.7
Anderton, B.H.8
-
56
-
-
0030868557
-
Lithium reduces Tau phosphorylation by inhibition of glycogen synthase kinase-3
-
Hong, M., Chen, D. C, Klein, P. S., and Lee, V. M. (1997) Lithium reduces Tau phosphorylation by inhibition of glycogen synthase kinase-3. J. Biol. Chem. 272, 25326-25332
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25326-25332
-
-
Hong, M.1
Chen, D.C.2
Klein, P.S.3
Lee, V.M.4
-
57
-
-
0029994754
-
Phosphorylation of Tau by glycogen synthase kinase-3β in intact mammalian cells. The effects on the organization and stability of microtubules
-
Lovestone, S., Hartley, C. L., Pearce, J., and Anderton, B. H. (1996) Phosphorylation of Tau by glycogen synthase kinase-3β in intact mammalian cells. the effects on the organization and stability of microtubules. Neuroscience 73, 1145-1157
-
(1996)
Neuroscience
, vol.73
, pp. 1145-1157
-
-
Lovestone, S.1
Hartley, C.L.2
Pearce, J.3
Anderton, B.H.4
-
58
-
-
76549122910
-
Possible role of Tau in mediating pathological effects of apoE4 in vivo prior to and following activation of the amyloid cascade
-
Inbar, D., Belinson, H., Rosenman, H., and Michaelson, D. M. (2010) Possible role of Tau in mediating pathological effects of apoE4 in vivo prior to and following activation of the amyloid cascade. Neurodegener. Dis. 7, 16-23
-
(2010)
Neurodegener. Dis.
, vol.7
, pp. 16-23
-
-
Inbar, D.1
Belinson, H.2
Rosenman, H.3
Michaelson, D.M.4
-
59
-
-
0033889344
-
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein Tau in the brains of transgenic mice
-
Tesseur, I., Van Dorpe, J., Spittaels, K., Van Den Haute, C, Moechars, D., and Van Leuven, F. (2000) Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein Tau in the brains of transgenic mice. Am. J. Pathol. 156, 951-964
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 951-964
-
-
Tesseur, I.1
Van Dorpe, J.2
Spittaels, K.3
Van Den Haute, C.4
Moechars, D.5
Van Leuven, F.6
-
60
-
-
7244253060
-
Increased Tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase. Modulation by zinc
-
Harris, F. M., Brecht, W. J., Xu, Q., Mahley, R. W., and Huang, Y. (2004) Increased Tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase. Modulation by zinc. J. Biol. Chem. 279, 44795-44801
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44795-44801
-
-
Harris, F.M.1
Brecht, W.J.2
Xu, Q.3
Mahley, R.W.4
Huang, Y.5
-
61
-
-
12144290271
-
Neuron-specific apolipoprotein E4 proteolysis is associated with increased Tau phosphorylation in brains of transgenic mice
-
Brecht, W. J., Harris, F. M., Chang, S., Tesseur, I., Yu, G.-Q., Xu, Q., Dee Fish, J., Wyss-Coray, T., Buttini, M., Mucke, L., Mahley, R. W., and Huang, Y. (2004) Neuron-specific apolipoprotein E4 proteolysis is associated with increased Tau phosphorylation in brains of transgenic mice. J. Neurosci. 24, 2527-2534
-
(2004)
J. Neurosci.
, vol.24
, pp. 2527-2534
-
-
Brecht, W.J.1
Harris, F.M.2
Chang, S.3
Tesseur, I.4
Yu, G.-Q.5
Xu, Q.6
Dee Fish, J.7
Wyss-Coray, T.8
Buttini, M.9
Mucke, L.10
Mahley, R.W.11
Huang, Y.12
-
62
-
-
84863029161
-
APOE genotype alters glial activation and loss of synaptic markers in mice
-
Zhu, Y., Nwabuisi-Heath, E., Dumanis, S. B., Tai, L. M., Yu, C, Rebeck, G. W., and La Du, M. J. (2012) APOE genotype alters glial activation and loss of synaptic markers in mice. Glia 60, 559-569
-
(2012)
Glia
, vol.60
, pp. 559-569
-
-
Zhu, Y.1
Nwabuisi-Heath, E.2
Dumanis, S.B.3
Tai, L.M.4
Yu, C.5
Rebeck, G.W.6
La Du, M.J.7
-
63
-
-
15744378392
-
Human apoE targeted replacement mouse lines. H-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior
-
Grootendorst, J., Bour, A., Vogel, E., Kelche, C, Sullivan, P. M., Dodart, J.-C, Bales, K., and Mathis, C. (2005) Human apoE targeted replacement mouse lines. h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior. Behav. Brain Res. 159, 1-14
-
(2005)
Behav. Brain Res.
, vol.159
, pp. 1-14
-
-
Grootendorst, J.1
Bour, A.2
Vogel, E.3
Kelche, C.4
Sullivan, P.M.5
Dodart, J.-C.6
Bales, K.7
Mathis, C.8
-
64
-
-
0032168460
-
Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice. Increased susceptibility of females
-
Raber, J., Wong, D., Buttini, M., Orth, M., Bellosta, S., Pitas, R. E., Mahley, R. W., and Mucke, L. (1998) Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice. Increased susceptibility of females. Proc. Natl. Acad. Sci. U. S. A. 95, 10914-10919
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 10914-10919
-
-
Raber, J.1
Wong, D.2
Buttini, M.3
Orth, M.4
Bellosta, S.5
Pitas, R.E.6
Mahley, R.W.7
Mucke, L.8
-
65
-
-
32544448231
-
Reduced hippocampal volume in non-demented carriers of the apolipoprotein E e4. Relation to chronological age and recognition memory
-
Lind, J., Larsson, A., Persson, J., Ingvar, M., Nilsson, L.-G., Bäckman, L., Adolfsson, R., Cruts, M., Sleegers, K., Van Broeckhoven, C, and Nyberg, L. (2006) Reduced hippocampal volume in non-demented carriers of the apolipoprotein E e4. Relation to chronological age and recognition memory. Neurosci. Lett. 396, 23-27
-
(2006)
Neurosci. Lett.
, vol.396
, pp. 23-27
-
-
Lind, J.1
Larsson, A.2
Persson, J.3
Ingvar, M.4
Nilsson, L.-G.5
Bäckman, L.6
Adolfsson, R.7
Cruts, M.8
Sleegers, K.9
Van Broeckhoven, C.10
Nyberg, L.11
-
66
-
-
59649117521
-
APOE polymorphism affects episodic memory among non demented elderly subjects
-
De Blasi, S., Montesanto, A., Martino, C, Dato, S., De Rango, F., Bruni, A. C, Mari, V., Feraco, E., and Passarino, G. (2009) APOE polymorphism affects episodic memory among non demented elderly subjects. Exp. Gerontol. 44, 224-227
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 224-227
-
-
De Blasi, S.1
Montesanto, A.2
Martino, C.3
Dato, S.4
De Rango, F.5
Bruni, A.C.6
Mari, V.7
Feraco, E.8
Passarino, G.9
-
67
-
-
58049154704
-
Additional evidence for antagonistic pleiotropic effects of APOE
-
Zetterberg, H, Alexander, D. M., Spandidos, D. A., and Blennow, K. (2009) Additional evidence for antagonistic pleiotropic effects of APOE. Alzheimers Dement. 5, 75
-
(2009)
Alzheimers Dement.
, vol.5
, pp. 75
-
-
Zetterberg, H.1
Alexander, D.M.2
Spandidos, D.A.3
Blennow, K.4
-
68
-
-
0036861774
-
Genetic variation in memory functioning
-
Nilsson, L.-G., Nyberg, L., and Bäckman, L. (2002) Genetic variation in memory functioning. Neurosci. Biobehav. Rev. 26, 841-848
-
(2002)
Neurosci. Biobehav. Rev.
, vol.26
, pp. 841-848
-
-
Nilsson, L.-G.1
Nyberg, L.2
Bäckman, L.3
-
69
-
-
15044360058
-
Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults. Results from the National Institute of Mental Health's BIOCARD Study
-
Greenwood, P. M., Lambert, C, Sunderland, T., and Parasuraman, R. (2005) Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults. Results from the National Institute of Mental Health's BIOCARD Study. Neuropsychology 19, 199-211
-
(2005)
Neuropsychology
, vol.19
, pp. 199-211
-
-
Greenwood, P.M.1
Lambert, C.2
Sunderland, T.3
Parasuraman, R.4
-
70
-
-
13244286594
-
Apolipoprotein e e4 allele and lorazepam effects on memory in high-functioning older adults
-
Pomara N, Willoughby, L., Wesnes, K., Greenblatt, D. J., and Sidtis, J. J. (2005) Apolipoprotein e e4 allele and lorazepam effects on memory in high-functioning older adults. Arch. Gen. Psychiatry 62, 209-216
-
(2005)
Arch. Gen. Psychiatry
, vol.62
, pp. 209-216
-
-
Pomara, N.1
Willoughby, L.2
Wesnes, K.3
Greenblatt, D.J.4
Sidtis, J.J.5
-
71
-
-
84877865229
-
Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex
-
Rodriguez, G. A., Burns, M. P., Weeber, E. J., and Rebeck, G. W. (2013) Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. Learn. Mem. 20, 256-266
-
(2013)
Learn. Mem.
, vol.20
, pp. 256-266
-
-
Rodriguez, G.A.1
Burns, M.P.2
Weeber, E.J.3
Rebeck, G.W.4
-
72
-
-
76749163252
-
Apolipoprotein E4 and sex affect neurobehavioral performance in primary school children
-
Acevedo, S. F., Piper, B. J., Craytor, M. J., Benice, T. S., and Raber, J. (2010) Apolipoprotein E4 and sex affect neurobehavioral performance in primary school children. Pediatr. Res. 67, 293-299
-
(2010)
Pediatr. Res.
, vol.67
, pp. 293-299
-
-
Acevedo, S.F.1
Piper, B.J.2
Craytor, M.J.3
Benice, T.S.4
Raber, J.5
-
73
-
-
0842330444
-
Efficacy of doublecortin as a marker to analyze the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus
-
Rao, M. S., and Shetty, A. K. (2004) Efficacy of doublecortin as a marker to analyze the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur. J. Neurosci. 19, 234-246
-
(2004)
Eur. J. Neurosci.
, vol.19
, pp. 234-246
-
-
Rao, M.S.1
Shetty, A.K.2
-
74
-
-
34147177548
-
The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells
-
Walker, T. L., Yasuda, T., Adams, D. J., and Bartlett, P. F. (2007) The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells. J. Neurosci. 27, 3734-3742
-
(2007)
J. Neurosci.
, vol.27
, pp. 3734-3742
-
-
Walker, T.L.1
Yasuda, T.2
Adams, D.J.3
Bartlett, P.F.4
-
75
-
-
23244458855
-
Adult neurogenesis in the mammalian central nervous system
-
Ming, G. L., and Song, H. (2005) Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 28, 223-250
-
(2005)
Annu. Rev. Neurosci.
, vol.28
, pp. 223-250
-
-
Ming, G.L.1
Song, H.2
-
76
-
-
0034668838
-
Neuronal apoptosis by apolipoprotein E4 through low density lipoprotein receptor-related protein and heterotrimeric GTPases
-
Hashimoto, Y., Jiang, H., Niikura, T., Ito, Y., Hagiwara, A., Umezawa, K., Abe, Y., Murayama, Y., and Nishimoto, I. (2000) Neuronal apoptosis by apolipoprotein E4 through low density lipoprotein receptor-related protein and heterotrimeric GTPases. J. Neurosci. 20, 8401-8409
-
(2000)
J. Neurosci.
, vol.20
, pp. 8401-8409
-
-
Hashimoto, Y.1
Jiang, H.2
Niikura, T.3
Ito, Y.4
Hagiwara, A.5
Umezawa, K.6
Abe, Y.7
Murayama, Y.8
Nishimoto, I.9
-
77
-
-
0032189866
-
Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis
-
Michikawa, M., and Yanagisawa, K. (1998) Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis. J. Neurosci. Res. 54, 58-67
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 58-67
-
-
Michikawa, M.1
Yanagisawa, K.2
-
78
-
-
34250308322
-
Apoptosis. A review of programmed cell death
-
Elmore, S. (2007) Apoptosis. A Review of Programmed Cell Death. Toxicol. Pathol. 35, 495-516
-
(2007)
Toxicol. Pathol.
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
79
-
-
0034623304
-
Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain
-
Biebl, M., Cooper, C. M., Winkler, J., and Kuhn, H. G. (2000) Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain. Neurosci. Lett. 291, 17-20
-
(2000)
Neurosci. Lett.
, vol.291
, pp. 17-20
-
-
Biebl, M.1
Cooper, C.M.2
Winkler, J.3
Kuhn, H.G.4
-
80
-
-
84875988066
-
Immature doublecortinpositive hippocampal neurons are important for learning but not for remembering
-
Vukovic, J., Borlikova, G. G., Ruitenberg, M. J., Robinson, G. J., Sullivan, R. K., Walker, T. L., and Bartlett, P. F. (2013) Immature doublecortinpositive hippocampal neurons are important for learning but not for remembering. J. Neurosci. 33, 6603-6613
-
(2013)
J. Neurosci.
, vol.33
, pp. 6603-6613
-
-
Vukovic, J.1
Borlikova, G.G.2
Ruitenberg, M.J.3
Robinson, G.J.4
Sullivan, R.K.5
Walker, T.L.6
Bartlett, P.F.7
-
81
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
De Calignon, A., Fox, L. M., Pitstick, R., Carlson, G. A., Bacskai, B. J., Spires-Jones, T. L., and Hyman, B. T. (2010) Caspase activation precedes and leads to tangles. Nature 464, 1201-1204
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
De Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
Spires-Jones, T.L.6
Hyman, B.T.7
-
82
-
-
78650659370
-
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
-
D'Amelio, M., Cavallucci, V., Middei, S., Marchetti, C, Pacioni, S., Ferri, A., Diamantini, A., De Zio, D., Carrara, P., Battistini, L., Moreno, S., Bacci, A., Ammassari-Teule, M., Marie, H., and Cecconi, F. (2011) Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat. Neurosci. 14, 69-76
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 69-76
-
-
D'Amelio, M.1
Cavallucci, V.2
Middei, S.3
Marchetti, C.4
Pacioni, S.5
Ferri, A.6
Diamantini, A.7
De Zio, D.8
Carrara, P.9
Battistini, L.10
Moreno, S.11
Bacci, A.12
Ammassari-Teule, M.13
Marie, H.14
Cecconi, F.15
-
83
-
-
80051569682
-
Amyloid-dependent and amyloid-independent stages of Alzheimer disease
-
Hyman, B. T. (2011) Amyloid-dependent and amyloid-independent stages of Alzheimer disease. Arch. Neurol. 68, 1062-1064
-
(2011)
Arch. Neurol.
, vol.68
, pp. 1062-1064
-
-
Hyman, B.T.1
-
84
-
-
79953291282
-
ApoE4-driven accumulation of intraneuronal oligomerized Aβ42 following activation of the amyloid cascade in vivo is mediated by a gain of function
-
Zepa, L., Frenkel, M., Belinson, H, Kariv-Inbal, Z., Kayed, R., Masliah, E., and Michaelson, D. M. (2011) ApoE4-driven accumulation of intraneuronal oligomerized Aβ42 following activation of the amyloid cascade in vivo is mediated by a gain of function. Int. J. Alzheimers Dis. 2011, 792070
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 792070
-
-
Zepa, L.1
Frenkel, M.2
Belinson, H.3
Kariv-Inbal, Z.4
Kayed, R.5
Masliah, E.6
Michaelson, D.M.7
-
85
-
-
84055213663
-
Adult hippocampal neurogenesis and its role in Alzheimer's disease
-
Mu, Y., and Gage, F. H. (2011) Adult hippocampal neurogenesis and its role in Alzheimer's disease. Mol. Neurodegener. 6, 85
-
(2011)
Mol. Neurodegener.
, vol.6
, pp. 85
-
-
Mu, Y.1
Gage, F.H.2
-
86
-
-
77950868172
-
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
-
Wang, J. M., Singh, C, Liu, L., Irwin, R. W., Chen, S., Chung, E. J., Thompson, R. F., and Brinton, R. D. (2010) Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. 107, 6498-6503
-
(2010)
Proc. Natl. Acad. Sci.
, vol.107
, pp. 6498-6503
-
-
Wang, J.M.1
Singh, C.2
Liu, L.3
Irwin, R.W.4
Chen, S.5
Chung, E.J.6
Thompson, R.F.7
Brinton, R.D.8
-
87
-
-
51849123324
-
Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease
-
Rodríguez, J. J., Jones, V. C, Tabuchi, M., Allan, S. M., Knight, E. M., La Ferla, F. M., Oddo, S., and Verkhratsky, A. (2008) Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PLoS ONE 3, e2935
-
(2008)
PLoS ONE
, vol.3
-
-
Rodríguez, J.J.1
Jones, V.C.2
Tabuchi, M.3
Allan, S.M.4
Knight, E.M.5
La Ferla, F.M.6
Oddo, S.7
Verkhratsky, A.8
-
88
-
-
0346458659
-
Increased hippocampal neurogenesis in Alzheimer's disease
-
Jin, K., Peel, A. L., Mao, X. O., Xie, L., Cottrell, B. A., Henshall, D. C, and Greenberg, D. A. (2004) Increased hippocampal neurogenesis in Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 101, 343-347
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 343-347
-
-
Jin, K.1
Peel, A.L.2
Mao, X.O.3
Xie, L.4
Cottrell, B.A.5
Henshall, D.C.6
Greenberg, D.A.7
-
89
-
-
71849113134
-
Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model
-
Yu, Y., He, J., Zhang, Y., Luo, H, Zhu, S., Yang, Y., Zhao, T., Wu, J., Huang, Y., Kong, J., Tan, Q., and Li, X.-M. (2009) Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus 19, 1247-1253
-
(2009)
Hippocampus
, vol.19
, pp. 1247-1253
-
-
Yu, Y.1
He, J.2
Zhang, Y.3
Luo, H.4
Zhu, S.5
Yang, Y.6
Zhao, T.7
Wu, J.8
Huang, Y.9
Kong, J.10
Tan, Q.11
Li, X.-M.12
-
90
-
-
38149116895
-
Adult neurogenesis is functionally associated with AD-like neurodegeneration
-
Chen, Q., Nakajima, A., Choi, S. H., Xiong, X., Sisodia, S. S., and Tang, Y.-P. (2008) Adult neurogenesis is functionally associated with AD-like neurodegeneration. Neurobiol. Dis. 29, 316-326
-
(2008)
Neurobiol. Dis.
, vol.29
, pp. 316-326
-
-
Chen, Q.1
Nakajima, A.2
Choi, S.H.3
Xiong, X.4
Sisodia, S.S.5
Tang, Y.-P.6
-
91
-
-
0344198502
-
Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis
-
Drapeau, E., Mayo, W., Aurousseau, C, Le Moal, M., Piazza, P.-V., and Abrous, D. N. (2003) Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc. Natl. Acad. Sci. 100, 14385-14390
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 14385-14390
-
-
Drapeau, E.1
Mayo, W.2
Aurousseau, C.3
Le Moal, M.4
Piazza, P.-V.5
Abrous, D.N.6
-
92
-
-
84876393414
-
Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1AE9 mice
-
Abbott, A. C, Calderon Toledo, C, Aranguiz, F. C, Inestrosa, N. C, and Varela-Nallar, L. (2013) Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1AE9 mice. J. Alzheimers Dis. 34, 873-885
-
(2013)
J. Alzheimers Dis.
, vol.34
, pp. 873-885
-
-
Abbott, A.C.1
Calderon Toledo, C.2
Aranguiz, F.C.3
Inestrosa, N.C.4
Varela-Nallar, L.5
-
93
-
-
13444283646
-
New neurons in the dentate gyrus are involved in the expression of enhanced long-term memory following environmental enrichment
-
Bruel-Jungerman, E., Laroche, S., and Rampon, C. (2005) New neurons in the dentate gyrus are involved in the expression of enhanced long-term memory following environmental enrichment. Eur. J. Neurosci. 21, 513-521
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 513-521
-
-
Bruel-Jungerman, E.1
Laroche, S.2
Rampon, C.3
-
94
-
-
25444533023
-
Exercise enhances learning and hippocampal neurogenesis in aged mice
-
Van Praag, H, Shubert, T., Zhao, C, and Gage, F. H. (2005) Exercise enhances learning and hippocampal neurogenesis in aged mice. J. Neurosci. 25, 8680-8685
-
(2005)
J. Neurosci.
, vol.25
, pp. 8680-8685
-
-
Van Praag, H.1
Shubert, T.2
Zhao, C.3
Gage, F.H.4
-
95
-
-
59649095732
-
Dentate gyrusspecific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats
-
Jessberger, S., Clark, R. E., Broadbent, N. J., Clemenson, G. D., Jr., Consiglio, A., Lie, D. C, Squire, L. R., and Gage, F. H. (2009) Dentate gyrusspecific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn. Mem. 16, 147-154
-
(2009)
Learn. Mem.
, vol.16
, pp. 147-154
-
-
Jessberger, S.1
Clark, R.E.2
Broadbent, N.J.3
Clemenson Jr., G.D.4
Consiglio, A.5
Lie, D.C.6
Squire, L.R.7
Gage, F.H.8
-
96
-
-
80052410357
-
The aging systemic milieu negatively regulates neurogenesis and cognitive function
-
Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N, Ding, Z., Eggel, A., Lucin, K. M., Czirr, E., Park, J.-S., Couillard-Després, S., Aigner, L., Li, G., Peskind, E. R., Kaye, J. A., Quinn, J. F., Galasko, D. R., Xie, X. S., Rando, T. A., and Wyss-Coray, T. (2011) The aging systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90-94
-
(2011)
Nature
, vol.477
, pp. 90-94
-
-
Villeda, S.A.1
Luo, J.2
Mosher, K.I.3
Zou, B.4
Britschgi, M.5
Bieri, G.6
Stan, T.M.7
Fainberg, N.8
Ding, Z.9
Eggel, A.10
Lucin, K.M.11
Czirr, E.12
Park, J.-S.13
Couillard- Després, S.14
Aigner, L.15
Li, G.16
Peskind, E.R.17
Kaye, J.A.18
Quinn, J.F.19
Galasko, D.R.20
Xie, X.S.21
Rando, T.A.22
Wyss-Coray, T.23
more..
-
97
-
-
78049467264
-
Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans
-
Coras, R., Siebzehnrubl, F. A., Pauli, E., Huttner, H. B., Njunting, M., Kobow, K., Villmann, C, Hahnen, E., Neuhuber, W., Weigel, D., Buchfelder, M., Stefan, H., Beck, H., Steindler, D. A., and Blümcke, I. (2010) Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain 133, 3359-3372
-
(2010)
Brain
, vol.133
, pp. 3359-3372
-
-
Coras, R.1
Siebzehnrubl, F.A.2
Pauli, E.3
Huttner, H.B.4
Njunting, M.5
Kobow, K.6
Villmann, C.7
Hahnen, E.8
Neuhuber, W.9
Weigel, D.10
Buchfelder, M.11
Stefan, H.12
Beck, H.13
Steindler, D.A.14
Blümcke, I.15
-
98
-
-
77951498581
-
New neurons and new memories. How does adult hippocampal neurogenesis affect learning and memory?
-
Deng, W., Aimone, J. B., and Gage, F. H. (2010) New neurons and new memories. How does adult hippocampal neurogenesis affect learning and memory? Nat Rev. Neurosci. 11, 339-350
-
(2010)
Nat Rev. Neurosci.
, vol.11
, pp. 339-350
-
-
Deng, W.1
Aimone, J.B.2
Gage, F.H.3
-
99
-
-
70450257814
-
GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knock-in mice
-
Li, G., Bien-Ly, N, Andrews-Zwilling, Y., Xu, Q., Bernardo, A., Ring, K., Halabisky, B., Deng, C, Mahley, R. W., and Huang, Y. (2009) GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knock-in mice. Cell Stem Cell 5, 634-645
-
(2009)
Cell Stem Cell
, vol.5
, pp. 634-645
-
-
Li, G.1
Bien-Ly, N.2
Andrews-Zwilling, Y.3
Xu, Q.4
Bernardo, A.5
Ring, K.6
Halabisky, B.7
Deng, C.8
Mahley, R.W.9
Huang, Y.10
-
100
-
-
70350448412
-
Apolipoprotein E4 domain interaction induces endoplasmic reticulum stress and impairs astrocyte function
-
Zhong, N, Ramaswamy, G., and Weisgraber, K. H. (2009) Apolipoprotein E4 domain interaction induces endoplasmic reticulum stress and impairs astrocyte function. J. Biol. Chem. 284, 27273-27280
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27273-27280
-
-
Zhong, N.1
Ramaswamy, G.2
Weisgraber, K.H.3
-
101
-
-
77954499888
-
Adult neurogenesis. A potential tool for early diagnosis in Alzheimer's disease?
-
Lopez-Toledano, M. A., Ali Faghihi, M., Patel, N. S., and Wahlestedt, C. (2010) Adult neurogenesis. A potential tool for early diagnosis in Alzheimer's disease? J. Alzheimers Dis. 20, 395-408
-
(2010)
J. Alzheimers Dis.
, vol.20
, pp. 395-408
-
-
Lopez-Toledano, M.A.1
Ali Faghihi, M.2
Patel, N.S.3
Wahlestedt, C.4
-
102
-
-
45749095797
-
Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis
-
Han, S. D., and Bondi, M. W. (2008) Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis. Alzheimers Dement. 4, 251-254
-
(2008)
Alzheimers Dement.
, vol.4
, pp. 251-254
-
-
Han, S.D.1
Bondi, M.W.2
|