메뉴 건너뛰기




Volumn 10, Issue 5, 2011, Pages 589-603

Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency

Author keywords

Dopamine; Glutamate; Latent inhibition; Prepulse inhibition; Selective attention

Indexed keywords

DIZOCILPINE; NUCLEAR RECEPTOR RELATED FACTOR 1;

EID: 79960015625     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2011.00698.x     Document Type: Article
Times cited : (37)

References (64)
  • 2
    • 0038352093 scopus 로고    scopus 로고
    • Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine.
    • Bäckman, C., You, Z.B., Perlmann, T. & Hoffer, B.J. (2003) Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine. Behav Brain Res 143, 95-100.
    • (2003) Behav Brain Res , vol.143 , pp. 95-100
    • Bäckman, C.1    You, Z.B.2    Perlmann, T.3    Hoffer, B.J.4
  • 3
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients.
    • Braff, D.L., Grillon, C. & Geyer, M.A. (1992) Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 49, 206-215.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1    Grillon, C.2    Geyer, M.A.3
  • 4
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies.
    • Braff, D.L., Geyer, M.A. & Swerdlow, N.R. (2001) Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology 156, 234-258.
    • (2001) Psychopharmacology , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 5
    • 9644268797 scopus 로고    scopus 로고
    • Recognition of visual stimuli and memory for spatial context in schizophrenic patients and healthy volunteers.
    • Brébion, G., David, A.S., Pilowsky, L.S. & Jones, H. (2004) Recognition of visual stimuli and memory for spatial context in schizophrenic patients and healthy volunteers. J Clin Exp Neuropsychol 26, 1093-1102.
    • (2004) J Clin Exp Neuropsychol , vol.26 , pp. 1093-1102
    • Brébion, G.1    David, A.S.2    Pilowsky, L.S.3    Jones, H.4
  • 6
    • 0036641819 scopus 로고    scopus 로고
    • Rodent models of prefrontal cortical function.
    • Brown, V.J. & Bowman, E.M. (2002) Rodent models of prefrontal cortical function. Trends Neurosci 25, 340-343.
    • (2002) Trends Neurosci , vol.25 , pp. 340-343
    • Brown, V.J.1    Bowman, E.M.2
  • 11
    • 35148821488 scopus 로고    scopus 로고
    • Mouse behavioral assays relevant to the symptoms of autism.
    • Crawley, J.N. (2007) Mouse behavioral assays relevant to the symptoms of autism. Brain Pathol 17, 448-459.
    • (2007) Brain Pathol , vol.17 , pp. 448-459
    • Crawley, J.N.1
  • 12
    • 0031019499 scopus 로고    scopus 로고
    • Perseveration in schizophrenia.
    • Crider, A. (1997) Perseveration in schizophrenia. Schizophr Bull 23, 63-74.
    • (1997) Schizophr Bull , vol.23 , pp. 63-74
    • Crider, A.1
  • 13
    • 57749169307 scopus 로고    scopus 로고
    • Impaired prepulse inhibition and prepulse-elicited reactivity but intact reflex circuit excitability in unmedicated schizophrenia patients: a comparison with healthy subjects and medicated schizophrenia patients.
    • Csomor, P.A., Yee, B.K., Feldon, J., Theodoridou, A., Studerus, E. & Vollenweider, F.X. (2009) Impaired prepulse inhibition and prepulse-elicited reactivity but intact reflex circuit excitability in unmedicated schizophrenia patients: a comparison with healthy subjects and medicated schizophrenia patients. Schizophr Bull 35, 244-255.
    • (2009) Schizophr Bull , vol.35 , pp. 244-255
    • Csomor, P.A.1    Yee, B.K.2    Feldon, J.3    Theodoridou, A.4    Studerus, E.5    Vollenweider, F.X.6
  • 14
    • 78049390633 scopus 로고    scopus 로고
    • Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon.
    • Cui, X., Pelekanos, M., Burne, T.H., McGrath, J.J. & Eyles, D.W. (2010) Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon. Neurosci Lett 486, 220-223.
    • (2010) Neurosci Lett , vol.486 , pp. 220-223
    • Cui, X.1    Pelekanos, M.2    Burne, T.H.3    McGrath, J.J.4    Eyles, D.W.5
  • 15
    • 8844286003 scopus 로고    scopus 로고
    • Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates.
    • Dalley, J.W., Cardinal, R.N. & Robbins, T.W. (2004) Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates. Neurosci Biobehav Rev 28, 771-784.
    • (2004) Neurosci Biobehav Rev , vol.28 , pp. 771-784
    • Dalley, J.W.1    Cardinal, R.N.2    Robbins, T.W.3
  • 16
    • 0026660230 scopus 로고
    • A two-trial memory task with automated recording: study in young and aged rats.
    • Dellu, F., Mayo, W., Cherkaoui, J., Le Moal, M. & Simon, H. (1992) A two-trial memory task with automated recording: study in young and aged rats. Brain Res 588, 132-139.
    • (1992) Brain Res , vol.588 , pp. 132-139
    • Dellu, F.1    Mayo, W.2    Cherkaoui, J.3    Le Moal, M.4    Simon, H.5
  • 17
    • 0037126171 scopus 로고    scopus 로고
    • Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity.
    • Eells, J.B., Lipska, B.K., Yeung, S.K., Misler, J.A. & Nikodem, V.M. (2002) Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity. Behav Brain Res 17, 267-275.
    • (2002) Behav Brain Res , vol.17 , pp. 267-275
    • Eells, J.B.1    Lipska, B.K.2    Yeung, S.K.3    Misler, J.A.4    Nikodem, V.M.5
  • 18
    • 33745242524 scopus 로고    scopus 로고
    • Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in Nurr1-null heterozygous mice.
    • Eells, J.B., Misler, J.A. & Nikodem, V.M. (2006) Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in Nurr1-null heterozygous mice. Neuroscience 140, 1117-1126.
    • (2006) Neuroscience , vol.140 , pp. 1117-1126
    • Eells, J.B.1    Misler, J.A.2    Nikodem, V.M.3
  • 20
    • 0027101872 scopus 로고
    • From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia.
    • Feldon, J. & Weiner, I. (1992) From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia. J Psychiatr Res 26, 345-366.
    • (1992) J Psychiatr Res , vol.26 , pp. 345-366
    • Feldon, J.1    Weiner, I.2
  • 21
    • 77749291977 scopus 로고    scopus 로고
    • Negative symptoms in schizophrenia: avolition and Occam's razor.
    • Foussias, G. & Remington, G. (2010) Negative symptoms in schizophrenia: avolition and Occam's razor. Schizophr Bull 36, 356-359.
    • (2010) Schizophr Bull , vol.36 , pp. 356-359
    • Foussias, G.1    Remington, G.2
  • 22
    • 0000546358 scopus 로고    scopus 로고
    • Measurement of startle response, prepulse inhibition and habituation.
    • Geyer, M.A. & Swerdlow, N.R. (1998) Measurement of startle response, prepulse inhibition and habituation. Curr Protoc Neurosci 8, 1-15.
    • (1998) Curr Protoc Neurosci , vol.8 , pp. 1-15
    • Geyer, M.A.1    Swerdlow, N.R.2
  • 25
    • 0008808158 scopus 로고
    • Acoustic variables in the modification of the startle reaction in the rat.
    • Hoffman, H.S. & Searle, J.L. (1965) Acoustic variables in the modification of the startle reaction in the rat. J Comp Physiol Psychol 60, 53-58.
    • (1965) J Comp Physiol Psychol , vol.60 , pp. 53-58
    • Hoffman, H.S.1    Searle, J.L.2
  • 26
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: version III - the final common pathway.
    • Howes, O.D. & Kapur, S. (2009) The dopamine hypothesis of schizophrenia: version III - the final common pathway. Schizophr Bull 35, 549-562.
    • (2009) Schizophr Bull , vol.35 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 28
    • 27844547616 scopus 로고    scopus 로고
    • The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease.
    • Jankovic, J., Chen, S. & Le, W.D. (2005) The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease. Prog Neurobiol 77, 128-138.
    • (2005) Prog Neurobiol , vol.77 , pp. 128-138
    • Jankovic, J.1    Chen, S.2    Le, W.D.3
  • 29
    • 10044247254 scopus 로고    scopus 로고
    • Age-dependent dopaminergic dysfunction in Nurr1 knockout mice.
    • Jiang, C., Wan, X., He, Y., Pan, T., Jankovic, J. & Le, W. (2005) Age-dependent dopaminergic dysfunction in Nurr1 knockout mice. Exp Neurol 191, 154-162.
    • (2005) Exp Neurol , vol.191 , pp. 154-162
    • Jiang, C.1    Wan, X.2    He, Y.3    Pan, T.4    Jankovic, J.5    Le, W.6
  • 31
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
    • Krystal, J.H., Karper, L.P., Seibyl, J.P., Freeman, G.K., Delaney, R., Bremner, J.D., Heninger, G.R., Bowers, M.B. Jr. & Charney, D.S. (1994) Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51, 199-214.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3    Freeman, G.K.4    Delaney, R.5    Bremner, J.D.6    Heninger, G.R.7    Bowers, M.B.8    Charney, D.S.9
  • 35
    • 4143049019 scopus 로고    scopus 로고
    • Acoustic startle response, prepulse inhibition, and spontaneous locomotor activity in MPTP-treated mice.
    • Leng, A., Yee, B.K., Feldon, J. & Ferger, B. (2004) Acoustic startle response, prepulse inhibition, and spontaneous locomotor activity in MPTP-treated mice. Behav Brain Res 154, 449-456.
    • (2004) Behav Brain Res , vol.154 , pp. 449-456
    • Leng, A.1    Yee, B.K.2    Feldon, J.3    Ferger, B.4
  • 36
    • 69249248178 scopus 로고    scopus 로고
    • Neural basis of psychosis-related behaviour in the infection model of schizophrenia.
    • Meyer, U. & Feldon, J. (2009) Neural basis of psychosis-related behaviour in the infection model of schizophrenia. Behav Brain Res 204, 322-334.
    • (2009) Behav Brain Res , vol.204 , pp. 322-334
    • Meyer, U.1    Feldon, J.2
  • 37
    • 77649274922 scopus 로고    scopus 로고
    • Epidemiology-driven neurodevelopmental animal models of schizophrenia.
    • Meyer, U. & Feldon, J. (2010) Epidemiology-driven neurodevelopmental animal models of schizophrenia. Prog Neurobiol 90, 285-326.
    • (2010) Prog Neurobiol , vol.90 , pp. 285-326
    • Meyer, U.1    Feldon, J.2
  • 38
    • 9644290888 scopus 로고    scopus 로고
    • Expression of the CS- and US-pre-exposure effects in the conditioned taste aversion paradigm and their abolition following systemic amphetamine treatment in C57BL6/J mice.
    • Meyer, U., Chang, D.L., Feldon, J. & Yee, B.K. (2004) Expression of the CS- and US-pre-exposure effects in the conditioned taste aversion paradigm and their abolition following systemic amphetamine treatment in C57BL6/J mice. Neuropsychopharmacology 29, 2140-2148.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2140-2148
    • Meyer, U.1    Chang, D.L.2    Feldon, J.3    Yee, B.K.4
  • 39
    • 23244437953 scopus 로고    scopus 로고
    • Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia.
    • Meyer, U., Feldon, J., Schedlowski, M. & Yee, B.K. (2005) Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia. Neurosci Biobehav Rev 29, 913-947.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 913-947
    • Meyer, U.1    Feldon, J.2    Schedlowski, M.3    Yee, B.K.4
  • 40
    • 46549087172 scopus 로고    scopus 로고
    • Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy.
    • Meyer, U., Engler, A., Weber, L., Schedlowski, M. & Feldon, J. (2008a) Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy. Neuroscience 154, 701-709.
    • (2008) Neuroscience , vol.154 , pp. 701-709
    • Meyer, U.1    Engler, A.2    Weber, L.3    Schedlowski, M.4    Feldon, J.5
  • 41
    • 38349115639 scopus 로고    scopus 로고
    • Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling.
    • Meyer, U., Murray, P.J., Urwyler, A., Yee, B.K., Schedlowski, M. & Feldon, J. (2008b) Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling. Mol Psychiatry 13, 208-221.
    • (2008) Mol Psychiatry , vol.13 , pp. 208-221
    • Meyer, U.1    Murray, P.J.2    Urwyler, A.3    Yee, B.K.4    Schedlowski, M.5    Feldon, J.6
  • 42
    • 41349105699 scopus 로고    scopus 로고
    • Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice.
    • Meyer, U., Nyffeler, M., Yee, B.K., Knuesel, I. & Feldon, J. (2008c) Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice. Brain Behav Immun 22, 469-486.
    • (2008) Brain Behav Immun , vol.22 , pp. 469-486
    • Meyer, U.1    Nyffeler, M.2    Yee, B.K.3    Knuesel, I.4    Feldon, J.5
  • 43
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia.
    • Mohn, A.R., Gainetdinov, R.R., Caron, M.G. & Koller, B.H. (1999) Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98, 427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 46
    • 33745190239 scopus 로고    scopus 로고
    • Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?
    • Powell, C.M. & Miyakawa, T. (2006) Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder? Biol Psychiatry 59, 1198-1207.
    • (2006) Biol Psychiatry , vol.59 , pp. 1198-1207
    • Powell, C.M.1    Miyakawa, T.2
  • 47
    • 34547423806 scopus 로고    scopus 로고
    • Adult mice with reduced Nurr1 expression: an animal model for schizophrenia.
    • Rojas, P., Joodmardi, E., Hong, Y., Perlmann, T. & Ogren, S.O. (2007) Adult mice with reduced Nurr1 expression: an animal model for schizophrenia. Mol Psychiatry 12, 756-766.
    • (2007) Mol Psychiatry , vol.12 , pp. 756-766
    • Rojas, P.1    Joodmardi, E.2    Hong, Y.3    Perlmann, T.4    Ogren, S.O.5
  • 48
    • 77953648004 scopus 로고    scopus 로고
    • Rapid increase of Nurr1 mRNA expression in limbic and cortical brain structures related to coping with depression-like behavior in mice.
    • Rojas, P., Joodmardi, E., Perlmann, T. & Ogren, S.O. (2010) Rapid increase of Nurr1 mRNA expression in limbic and cortical brain structures related to coping with depression-like behavior in mice. J Neurosci Res 88, 2284-2293.
    • (2010) J Neurosci Res , vol.88 , pp. 2284-2293
    • Rojas, P.1    Joodmardi, E.2    Perlmann, T.3    Ogren, S.O.4
  • 50
  • 51
    • 33845746199 scopus 로고    scopus 로고
    • How to make a mesodiencephalic dopaminergic neuron.
    • Smidt, M.P. & Burbach, J.P. (2007) How to make a mesodiencephalic dopaminergic neuron. Nat Rev Neurosci 8, 21-32.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 21-32
    • Smidt, M.P.1    Burbach, J.P.2
  • 52
    • 0031720755 scopus 로고    scopus 로고
    • Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia.
    • Swerdlow, N.R. & Geyer, M.A. (1998) Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull 24, 285-301.
    • (1998) Schizophr Bull , vol.24 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 53
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges.
    • Swerdlow, N.R., Geyer, M.A. & Braff, D.L. (2001) Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology 156, 194-215.
    • (2001) Psychopharmacology , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 54
    • 12344254627 scopus 로고    scopus 로고
    • Phenotype of schizophrenia: a review and formulation.
    • Tamminga, C.A. & Holcomb, H.H. (2005) Phenotype of schizophrenia: a review and formulation. Mol Psychiatry 10, 27-39.
    • (2005) Mol Psychiatry , vol.10 , pp. 27-39
    • Tamminga, C.A.1    Holcomb, H.H.2
  • 55
    • 64749106515 scopus 로고    scopus 로고
    • Schizophrenia, "just the facts" 4. Clinical features and conceptualization.
    • Tandon, R., Nasrallah, H.A. & Keshavan, M.S. (2009) Schizophrenia, "just the facts" 4. Clinical features and conceptualization. Schizophr Research 110, 1-23.
    • (2009) Schizophr Research , vol.110 , pp. 1-23
    • Tandon, R.1    Nasrallah, H.A.2    Keshavan, M.S.3
  • 56
    • 10444250176 scopus 로고    scopus 로고
    • Function and dysfunction of the startle reaction in humans.
    • Valls-Solé, J. (2004) Function and dysfunction of the startle reaction in humans. Rev Neurol 39, 946-955.
    • (2004) Rev Neurol , vol.39 , pp. 946-955
    • Valls-Solé, J.1
  • 57
    • 75349096497 scopus 로고    scopus 로고
    • A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia.
    • Vuillermot, S., Weber, L., Feldon, J. & Meyer, U. (2010) A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. J Neurosci 30, 1270-1287.
    • (2010) J Neurosci , vol.30 , pp. 1270-1287
    • Vuillermot, S.1    Weber, L.2    Feldon, J.3    Meyer, U.4
  • 58
    • 0038624724 scopus 로고    scopus 로고
    • The two-headed latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment.
    • Weiner, I. (2003) The two-headed latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment. Psychopharmacology 169, 257-297.
    • (2003) Psychopharmacology , vol.169 , pp. 257-297
    • Weiner, I.1
  • 60
    • 33646524277 scopus 로고    scopus 로고
    • Reduction of dopamine-related transcription factors Nurr1 and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders.
    • Xing, G., Zhang, L., Russell, S. & Post, R. (2006) Reduction of dopamine-related transcription factors Nurr1 and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders. Schizophr Res 84, 36-56.
    • (2006) Schizophr Res , vol.84 , pp. 36-56
    • Xing, G.1    Zhang, L.2    Russell, S.3    Post, R.4
  • 61
    • 69249228701 scopus 로고    scopus 로고
    • Distinct forms of prepulse inhibition disruption distinguishable by the associated changes in prepulse-elicited reaction.
    • Yee, B.K. & Feldon, J. (2009) Distinct forms of prepulse inhibition disruption distinguishable by the associated changes in prepulse-elicited reaction. Behav Brain Res 204, 387-395.
    • (2009) Behav Brain Res , vol.204 , pp. 387-395
    • Yee, B.K.1    Feldon, J.2
  • 62
    • 5044237888 scopus 로고    scopus 로고
    • The effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice.
    • Yee, B.K., Chang, D.L. & Feldon, J. (2004) The effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice. Neuropsychopharmacology 29, 1865-1877.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1865-1877
    • Yee, B.K.1    Chang, D.L.2    Feldon, J.3
  • 64
    • 0000190727 scopus 로고    scopus 로고
    • Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system.
    • Zetterström, R.H., Williams, R., Perlmann, T. & Olson, L. (1996) Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Brain Res Mol Brain Res 41, 111-120.
    • (1996) Brain Res Mol Brain Res , vol.41 , pp. 111-120
    • Zetterström, R.H.1    Williams, R.2    Perlmann, T.3    Olson, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.