메뉴 건너뛰기




Volumn 19, Issue 1, 2014, Pages 1-18

Green tea catechins: A fresh flavor to anticancer therapy

Author keywords

Anticancer mechanisms; EGCG; Green tea catechins; Synergetic effects; Therapeutic agents

Indexed keywords

ANTINEOPLASTIC AGENT; CATECHIN; CATECHIN DERIVATIVE; CATECHOL DERIVATIVE; CYTOTOXIC AGENT; EPICATECHIN GALLATE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; FLUOROURACIL; GLUTATHIONE TRANSFERASE; GLYCOGEN SYNTHASE KINASE 3; GREEN TEA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OXALIPLATIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHENOL DERIVATIVE; POLYPHENON E; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 8; SOMATOMEDIN C; SULINDAC; TAMOXIFEN; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84892754530     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0908-5     Document Type: Review
Times cited : (65)

References (144)
  • 1
    • 79959538813 scopus 로고    scopus 로고
    • The chemistry and biotransformation of tea constituents
    • Sang S, Lambert JD, Ho C-T, Yang CS (2011) The chemistry and biotransformation of tea constituents. Pharmacol Res 64:87-99
    • (2011) Pharmacol Res , vol.64 , pp. 87-99
    • Sang, S.1    Lambert, J.D.2    Ho, C.-T.3    Yang, C.S.4
  • 2
    • 67649449180 scopus 로고    scopus 로고
    • Cancer prevention by tea: Animal studies, molecular mechanisms and human relevance
    • Yang CS, Wang X, Lu G, Picinich SC (2009) Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer 9:429-439
    • (2009) Nat Rev Cancer , vol.9 , pp. 429-439
    • Yang, C.S.1    Wang, X.2    Lu, G.3    Picinich, S.C.4
  • 3
    • 33749446855 scopus 로고    scopus 로고
    • Metabolism of green tea catechins: An overview
    • Feng WY (2006) Metabolism of green tea catechins: an overview. Curr Drug Metab 7:755-809
    • (2006) Curr Drug Metab , vol.7 , pp. 755-809
    • Feng, W.Y.1
  • 4
    • 0033118504 scopus 로고    scopus 로고
    • Angiogenesis inhibited by drinking tea
    • Cao Y, Cao R (1999) Angiogenesis inhibited by drinking tea. Nature 398:381
    • (1999) Nature , vol.398 , pp. 381
    • Cao, Y.1    Cao, R.2
  • 5
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
    • Singh BN, Shankar S, Srivastava RK (2011) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol 82:1807-1821
    • (2011) Biochem Pharmacol , vol.82 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 6
    • 35348923465 scopus 로고    scopus 로고
    • Tea and cancer prevention: Molecular mechanisms and human relevance
    • Yang CS, Lambert JD, Ju J, Lu G, Sang S (2007) Tea and cancer prevention: molecular mechanisms and human relevance. Toxicol Appl Pharm 224:265-273
    • (2007) Toxicol Appl Pharm , vol.224 , pp. 265-273
    • Yang, C.S.1    Lambert, J.D.2    Ju, J.3    Lu, G.4    Sang, S.5
  • 7
    • 0038121053 scopus 로고    scopus 로고
    • Tea catechins and polyphenols: Health effects, metabolism, and antioxidant functions
    • Higdon JV, Frei B (2003) Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci 43(1):89-143
    • (2003) Crit Rev Food Sci , vol.43 , Issue.1 , pp. 89-143
    • Higdon, J.V.1    Frei, B.2
  • 8
    • 0032953802 scopus 로고    scopus 로고
    • Synergistic effects of (-)-epigallocatechin gallate with (-)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9
    • Suganuma M, Okabe S, Kai Y, Sueoka N, Sueoka E, Fujiki H (1999) Synergistic effects of (-)-epigallocatechin gallate with (-)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9. Cancer Res 59:44-47
    • (1999) Cancer Res , vol.59 , pp. 44-47
    • Suganuma, M.1    Okabe, S.2    Kai, Y.3    Sueoka, N.4    Sueoka, E.5    Fujiki, H.6
  • 9
    • 62249140928 scopus 로고    scopus 로고
    • Efficient procedure for isolating methylated catechins from green tea and effective simultaneous analysis of ten catechins, three purine alkaloids, and gallic acid in tea by high-performance liquid chromatography with diode array detection
    • Hu B, Wang L, Zhou B, Zhang X, Sun Y, Ye H et al (2009) Efficient procedure for isolating methylated catechins from green tea and effective simultaneous analysis of ten catechins, three purine alkaloids, and gallic acid in tea by high-performance liquid chromatography with diode array detection. J Chromatogr A 1216:3223-3231
    • (2009) J Chromatogr A , vol.1216 , pp. 3223-3231
    • Hu, B.1    Wang, L.2    Zhou, B.3    Zhang, X.4    Sun, Y.5    Ye, H.6
  • 10
    • 77955439007 scopus 로고    scopus 로고
    • New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin
    • Saha A, Kuzuhara T, Echigo N, Suganuma M, Fujiki H (2010) New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin. Cancer Prev Res 3:953-962
    • (2010) Cancer Prev Res , vol.3 , pp. 953-962
    • Saha, A.1    Kuzuhara, T.2    Echigo, N.3    Suganuma, M.4    Fujiki, H.5
  • 11
    • 0035937335 scopus 로고    scopus 로고
    • EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells
    • Jung YD, Kim MS, Shin BA, Chay KO, Ahn BW, Liu W et al (2001) EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. BRIT J Cancer 84:844
    • (2001) BRIT J Cancer , vol.84 , pp. 844
    • Jung, Y.D.1    Kim, M.S.2    Shin, B.A.3    Chay, K.O.4    Ahn, B.W.5    Liu, W.6
  • 12
    • 17644401337 scopus 로고    scopus 로고
    • Epigallocatechin gallate and polyphenon e inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells
    • Shimizu M, Deguchi A, Lim JT, Moriwaki H, Kopelovich L, Weinstein IB (2005) (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells. Clin Cancer Res 11:2735-2746
    • (2005) Clin Cancer Res , vol.11 , pp. 2735-2746
    • Shimizu, M.1    Deguchi, A.2    Lim, J.T.3    Moriwaki, H.4    Kopelovich, L.5    Weinstein, I.B.6
  • 13
    • 0031590962 scopus 로고    scopus 로고
    • Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7, 12-dimethylbenz (\i[a\/i[) anthracene
    • Hirose M, Mizoguchi Y, Yaono M, Tanaka H, Yamaguchi T, Shirai T (1997) Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7, 12-dimethylbenz (\i[a\/i[) anthracene. Cancer Lett 112:141-147
    • (1997) Cancer Lett , vol.112 , pp. 141-147
    • Hirose, M.1    Mizoguchi, Y.2    Yaono, M.3    Tanaka, H.4    Yamaguchi, T.5    Shirai, T.6
  • 14
    • 34249002243 scopus 로고    scopus 로고
    • Chemopreventive effect of aerosolized polyphenon e on lung tumorigenesis in A/J mice
    • Yan Y, Cook J, McQuillan J, Zhang G, Hitzman CJ, Wang Y et al (2007) Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice. Neoplasia 9:401
    • (2007) Neoplasia , vol.9 , pp. 401
    • Yan, Y.1    Cook, J.2    McQuillan, J.3    Zhang, G.4    Hitzman, C.J.5    Wang, Y.6
  • 15
    • 20444480574 scopus 로고    scopus 로고
    • Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of polyphenon e in healthy individuals
    • Chow HH, Hakim IA, Vining DR, Crowell JA, Ranger-Moore J, Chew WM et al (2005) Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of polyphenon E in healthy individuals. Clin Cancer Res 11:4627-4633
    • (2005) Clin Cancer Res , vol.11 , pp. 4627-4633
    • Chow, H.H.1    Hakim, I.A.2    Vining, D.R.3    Crowell, J.A.4    Ranger-Moore, J.5    Chew, W.M.6
  • 16
    • 78650994500 scopus 로고    scopus 로고
    • EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment
    • Chen D, Wan SB, Yang H, Yuan J, Chan TH, Dou QP (2011) EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment. Adv Clin Chem 53:155
    • (2011) Adv Clin Chem , vol.53 , pp. 155
    • Chen, D.1    Wan, S.B.2    Yang, H.3    Yuan, J.4    Chan, T.H.5    Dou, Q.P.6
  • 17
    • 70549097006 scopus 로고    scopus 로고
    • Green tea polyphenols for prostate cancer chemoprevention: A translational perspective
    • Johnson J, Bailey H, Mukhtar H (2010) Green tea polyphenols for prostate cancer chemoprevention: a translational perspective. Phytomedicine 17:3-13
    • (2010) Phytomedicine , vol.17 , pp. 3-13
    • Johnson, J.1    Bailey, H.2    Mukhtar, H.3
  • 18
    • 58149288672 scopus 로고    scopus 로고
    • Green tea consumption and risk of stomach cancer: A metaanalysis of epidemiologic studies
    • Myung SK, Bae WK, Oh SM, Kim Y, Ju W, Sung J et al (2009) Green tea consumption and risk of stomach cancer: a metaanalysis of epidemiologic studies. Int J Cancer 124:670-677
    • (2009) Int J Cancer , vol.124 , pp. 670-677
    • Myung, S.K.1    Bae, W.K.2    Oh, S.M.3    Kim, Y.4    Ju, W.5    Sung, J.6
  • 19
    • 84869209964 scopus 로고    scopus 로고
    • Green tea consumption and risk of esophageal cancer: A meta-Analysis of epidemiologic studies
    • Zheng P, H-m Zheng, X-m Deng (2012) Green tea consumption and risk of esophageal cancer: a meta-Analysis of epidemiologic studies. BMC gastroenterol 12:165
    • (2012) BMC Gastroenterol , vol.12 , pp. 165
    • Zheng, P.1    Zheng, H.2    Deng, X.3
  • 20
    • 79958724660 scopus 로고    scopus 로고
    • Green tea drinking habits and esophageal cancer in southern China: A case-control study
    • Chen Z, Chen Q, Xia H, Lin J (2011) Green tea drinking habits and esophageal cancer in southern China: a case-control study. Asian Pac J Cancer Prev 12:229-233
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 229-233
    • Chen, Z.1    Chen, Q.2    Xia, H.3    Lin, J.4
  • 21
    • 24944492224 scopus 로고    scopus 로고
    • Green tea intake ACE gene polymorphism and breast cancer risk among Chinese women in Singapore
    • Yuan J-M, Koh W-P, Sun C-L, Lee H-P, Mimi CY (2005) Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore. Carcinogenesis 26:1389-1394
    • (2005) Carcinogenesis , vol.26 , pp. 1389-1394
    • Yuan, J.-M.1    Koh, W.-P.2    Sun, C.-L.3    Lee, H.-P.4    Mimi, C.Y.5
  • 22
    • 84863078577 scopus 로고    scopus 로고
    • Smoking, green tea consumption, genetic polymorphisms in the insulin-like growth factors and lung cancer risk
    • Lin IH, Ho ML, Chen HY, Lee HS, Huang CC, Chu YH et al (2012) Smoking, green tea consumption, genetic polymorphisms in the insulin-like growth factors and lung cancer risk. PLoS ONE 7:e30951
    • (2012) PLoS ONE , vol.7
    • Lin, I.H.1    Ho, M.L.2    Chen, H.Y.3    Lee, H.S.4    Huang, C.C.5    Chu, Y.H.6
  • 24
    • 0042334847 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon e in healthy individuals
    • Chow HH, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA et al (2003) Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res 9:3312-3319
    • (2003) Clin Cancer Res , vol.9 , pp. 3312-3319
    • Chow, H.H.1    Cai, Y.2    Hakim, I.A.3    Crowell, J.A.4    Shahi, F.5    Brooks, C.A.6
  • 25
    • 74049144587 scopus 로고    scopus 로고
    • Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions
    • Tsao AS, Liu D, Martin J, Tang XM, Lee JJ, El-Naggar AK et al (2009) Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev Res 2:931-941
    • (2009) Cancer Prev Res , vol.2 , pp. 931-941
    • Tsao, A.S.1    Liu, D.2    Martin, J.3    Tang, X.M.4    Lee, J.J.5    El-Naggar, A.K.6
  • 26
    • 0037443797 scopus 로고    scopus 로고
    • A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma
    • Jatoi A, Ellison N, Burch PA, Sloan JA, Dakhil SR, Novotny P et al (2003) A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer 97:1442-1446
    • (2003) Cancer , vol.97 , pp. 1442-1446
    • Jatoi, A.1    Ellison, N.2    Burch, P.A.3    Sloan, J.A.4    Dakhil, S.R.5    Novotny, P.6
  • 27
    • 31544477698 scopus 로고    scopus 로고
    • Phase IIa chemoprevention trial of green tea polyphenols in high-risk individuals of liver cancer: Modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine
    • Luo H, Tang L, Tang M, Billam M, Huang T, Yu J et al (2006) Phase IIa chemoprevention trial of green tea polyphenols in high-risk individuals of liver cancer: modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Carcinogenesis 27:262-268
    • (2006) Carcinogenesis , vol.27 , pp. 262-268
    • Luo, H.1    Tang, L.2    Tang, M.3    Billam, M.4    Huang, T.5    Yu, J.6
  • 28
    • 84876488340 scopus 로고    scopus 로고
    • Molecular mechanism of the inhibition of EGCG on the Alzheimer's Ab1-42 dimer
    • Zhang T, Zhang J, Derreumaux P, Mu Y (2013) Molecular mechanism of the inhibition of EGCG on the Alzheimer's Ab1-42 dimer. J Phys Chem B 117:3993-4002
    • (2013) J Phys Chem B , vol.117 , pp. 3993-4002
    • Zhang, T.1    Zhang, J.2    Derreumaux, P.3    Mu, Y.4
  • 29
    • 84862783302 scopus 로고    scopus 로고
    • Novel epigallocatechin gallate (EGCG) analogs activate AMP-Activated protein kinase pathway and target cancer stem cells
    • Chen D, Pamu S, Cui Q, Chan TH, Dou QP (2012) Novel epigallocatechin gallate (EGCG) analogs activate AMP-Activated protein kinase pathway and target cancer stem cells. Bioorgan Med Chem 20:3031-3037
    • (2012) Bioorgan Med Chem , vol.20 , pp. 3031-3037
    • Chen, D.1    Pamu, S.2    Cui, Q.3    Chan, T.H.4    Dou, Q.P.5
  • 30
    • 33845705480 scopus 로고    scopus 로고
    • Dietary polyphenolic phytochemicals-Promising cancer chemopreventive agents in humans? A review of their clinical properties
    • Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ (2007) Dietary polyphenolic phytochemicals-Promising cancer chemopreventive agents in humans? A review of their clinical properties. Int J Cancer 120:451-458
    • (2007) Int J Cancer , vol.120 , pp. 451-458
    • Thomasset, S.C.1    Berry, D.P.2    Garcea, G.3    Marczylo, T.4    Steward, W.P.5    Gescher, A.J.6
  • 31
    • 77958020749 scopus 로고    scopus 로고
    • Green tea and cancer prevention
    • Yang CS, Wang X (2010) Green tea and cancer prevention. Nutr Cancer 62:931-937
    • (2010) Nutr Cancer , vol.62 , pp. 931-937
    • Yang, C.S.1    Wang, X.2
  • 32
    • 33645094927 scopus 로고    scopus 로고
    • Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate
    • Khan N, Afaq F, Saleem M, Ahmad N, Mukhtar H (2006) Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res 66:2500-2505
    • (2006) Cancer Res , vol.66 , pp. 2500-2505
    • Khan, N.1    Afaq, F.2    Saleem, M.3    Ahmad, N.4    Mukhtar, H.5
  • 33
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh Y-J (2003) Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3:768-780
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.-J.1
  • 34
    • 0043067996 scopus 로고    scopus 로고
    • Role of p53 and NF-jB in epigallocatechin-3-gallateinduced apoptosis of LNCaP cells
    • Hastak K,Gupta S,Ahmad N,AgarwalMK,AgarwalML,Mukhtar H (2003) Role of p53 and NF-jB in epigallocatechin-3-gallateinduced apoptosis of LNCaP cells. Oncogene 22:4851-4859
    • (2003) Oncogene , vol.22 , pp. 4851-4859
    • Hastak, K.1    Gupta, S.2    Ahmad, N.3    Agarwal, M.K.4    Agarwal, M.L.5    Mukhtar, H.6
  • 35
    • 77956178353 scopus 로고    scopus 로고
    • The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention
    • Lambert JD, Elias RJ (2010) The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch Biochem Biophys 501:65-72
    • (2010) Arch Biochem Biophys , vol.501 , pp. 65-72
    • Lambert, J.D.1    Elias, R.J.2
  • 36
    • 0141639855 scopus 로고    scopus 로고
    • Antioxidant activity of tea polyphenols in vivo: Evidence from animal studies
    • Frei B, Higdon JV (2003) Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr 133:3275S-3284S
    • (2003) J Nutr , vol.133
    • Frei, B.1    Higdon, J.V.2
  • 37
    • 37649006065 scopus 로고    scopus 로고
    • Tea catechin consumption reduces circulating oxidized low-density lipoprotein
    • Inami S, Takano M, Yamamoto M, Murakami D, Tajika K, Yodogawa K et al (2007) Tea catechin consumption reduces circulating oxidized low-density lipoprotein. Int Heart J 48:725-732
    • (2007) Int Heart J , vol.48 , pp. 725-732
    • Inami, S.1    Takano, M.2    Yamamoto, M.3    Murakami, D.4    Tajika, K.5    Yodogawa, K.6
  • 38
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-jB pathway in the treatment of inflammation and cancer
    • Yamamoto Y, Gaynor RB (2001) Therapeutic potential of inhibition of the NF-jB pathway in the treatment of inflammation and cancer. J Clin Invest 107:135-142
    • (2001) J Clin Invest , vol.107 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 39
    • 0030799429 scopus 로고    scopus 로고
    • Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols,-)-epigallocatechin gallate, and theaflavins
    • Dong Z, W-y Ma, Huang C, Yang CS (1997) Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res 57:4414-4419
    • (1997) Cancer Res , vol.57 , pp. 4414-4419
    • Dong, Z.1    Huang, C.2    Yang, C.S.3
  • 40
    • 0036546501 scopus 로고    scopus 로고
    • NF-jB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, LiZW(2002) NF-jB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2:301-310
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Lizw, G.3
  • 41
    • 0026695822 scopus 로고
    • Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: Possible role in cancer chemoprevention
    • Khan SG, Katiyar SK, Agarwal R, Mukhtar H (1992) Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention. Cancer Res 52:4050-4052
    • (1992) Cancer Res , vol.52 , pp. 4050-4052
    • Khan, S.G.1    Katiyar, S.K.2    Agarwal, R.3    Mukhtar, H.4
  • 42
    • 84872159740 scopus 로고    scopus 로고
    • Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress
    • Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF et al (2013) Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress. Free Radic Bio Med 56:102-111
    • (2013) Free Radic Bio Med , vol.56 , pp. 102-111
    • Reuland, D.J.1    Khademi, S.2    Castle, C.J.3    Irwin, D.C.4    McCord, J.M.5    Miller, B.F.6
  • 43
    • 39249085843 scopus 로고    scopus 로고
    • Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
    • Na H-K, Surh Y-J (2008) Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food Chem Toxicol 46:1271-1278
    • (2008) Food Chem Toxicol , vol.46 , pp. 1271-1278
    • Na, H.-K.1    Surh, Y.-J.2
  • 44
    • 20044385140 scopus 로고    scopus 로고
    • Carcinogenesis, cancer therapy and chemoprevention
    • Blagosklonny M (2005) Carcinogenesis, cancer therapy and chemoprevention. Cell Death Differ 12:592-602
    • (2005) Cell Death Differ , vol.12 , pp. 592-602
    • Blagosklonny, M.1
  • 45
    • 33845636448 scopus 로고    scopus 로고
    • Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo
    • Thangapazham RL, Singh AK, Sharma A, Warren J, Gaddipati JP, Maheshwari RK (2007) Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo. Cancer Lett 245:232
    • (2007) Cancer Lett , vol.245 , pp. 232
    • Thangapazham, R.L.1    Singh, A.K.2    Sharma, A.3    Warren, J.4    Gaddipati, J.P.5    Maheshwari, R.K.6
  • 46
    • 28544452861 scopus 로고    scopus 로고
    • Inhibition of intestinal tumorigenesis in Apcmin/? Mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea
    • Ju J, Hong J, Zhou JN, Pan Z, Bose M, Liao J et al (2005) Inhibition of intestinal tumorigenesis in Apcmin/? mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea. Cancer Res 65:10623-10631
    • (2005) Cancer Res , vol.65 , pp. 10623-10631
    • Ju, J.1    Hong, J.2    Zhou, J.N.3    Pan, Z.4    Bose, M.5    Liao, J.6
  • 47
    • 4444307804 scopus 로고    scopus 로고
    • Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines
    • Huh SW, Bae SM, Kim YW, Lee JM, Namkoong SE, Lee IP et al (2004) Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines. Gynecol Oncol 94:760
    • (2004) Gynecol Oncol , vol.94 , pp. 760
    • Huh, S.W.1    Bae, S.M.2    Kim, Y.W.3    Lee, J.M.4    Namkoong, S.E.5    Lee, I.P.6
  • 48
    • 0029810269 scopus 로고    scopus 로고
    • Cell cycle control of DNA replication
    • Stillman B (1996) Cell cycle control of DNA replication. Science 274:1659-1663
    • (1996) Science , vol.274 , pp. 1659-1663
    • Stillman, B.1
  • 49
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs
    • Graña X, Reddy EP (1995) Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11:211
    • (1995) Oncogene , vol.11 , pp. 211
    • Graña, X.1    Reddy, E.P.2
  • 50
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg EA (1995) Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays 17:471-480
    • (1995) BioEssays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 51
    • 9244239811 scopus 로고    scopus 로고
    • G1 cell-cycle control and cancer
    • Massague J (2004) G1 cell-cycle control and cancer. Nature 432:298-306
    • (2004) Nature , vol.432 , pp. 298-306
    • Massague, J.1
  • 52
    • 13544258719 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate causes the p21/WAF1-mediated G(1)-phase arrest of cell cycle and inhibits matrix metalloproteinase-9 expression in TNF-Alpha-induced vascular smooth muscle cells
    • Kim CH, Moon SK (2005) Epigallocatechin-3-gallate causes the p21/WAF1-mediated G(1)-phase arrest of cell cycle and inhibits matrix metalloproteinase-9 expression in TNF-Alpha-induced vascular smooth muscle cells. Arch Biochem Biophys 435:264-272
    • (2005) Arch Biochem Biophys , vol.435 , pp. 264-272
    • Kim, C.H.1    Moon, S.K.2
  • 53
    • 33744969549 scopus 로고    scopus 로고
    • Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells
    • Peng G, Wargovich MJ, Dixon DA (2006) Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells. Cancer Lett 238:260-270
    • (2006) Cancer Lett , vol.238 , pp. 260-270
    • Peng, G.1    Wargovich, M.J.2    Dixon, D.A.3
  • 54
    • 0034730948 scopus 로고    scopus 로고
    • Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells
    • Tan X, Hu D, Li S, Han Y, Zhang Y, Zhou D (2000) Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. Cancer Lett 158:1-6
    • (2000) Cancer Lett , vol.158 , pp. 1-6
    • Tan, X.1    Hu, D.2    Li, S.3    Han, Y.4    Zhang, Y.5    Zhou, D.6
  • 55
    • 79959740010 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-jB in human dermal fibroblasts
    • Han DW, Lee MH, Kim HH, Hyon SH, Park JC (2011) Epigallocatechin-3- gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-jB in human dermal fibroblasts. Acta Pharmacol Sin 32:637-646
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 637-646
    • Han, D.W.1    Lee, M.H.2    Kim, H.H.3    Hyon, S.H.4    Park, J.C.5
  • 56
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J (2003) Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3:11-22
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 57
    • 0034668148 scopus 로고    scopus 로고
    • Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents
    • Agarwal R (2000) Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochem Pharmacol 60:1051-1059
    • (2000) Biochem Pharmacol , vol.60 , pp. 1051-1059
    • Agarwal, R.1
  • 58
    • 67650747279 scopus 로고    scopus 로고
    • Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signaling
    • Wu D, Guo Z, Ren Z, Guo W, Meydani SN (2009) Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signaling. Free Radic Bio Med 47:636-643
    • (2009) Free Radic Bio Med , vol.47 , pp. 636-643
    • Wu, D.1    Guo, Z.2    Ren, Z.3    Guo, W.4    Meydani, S.N.5
  • 59
    • 33646526291 scopus 로고    scopus 로고
    • The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells
    • Lin SC, Li WC, Shih JW, Hong KF, Pan YR, Lin JJ (2006) The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells. Cancer Lett 236:80-88
    • (2006) Cancer Lett , vol.236 , pp. 80-88
    • Lin, S.C.1    Li, W.C.2    Shih, J.W.3    Hong, K.F.4    Pan, Y.R.5    Lin, J.J.6
  • 60
    • 23044507681 scopus 로고    scopus 로고
    • Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma
    • Baatout S, Derradji H, Jacquet P, Mergeay M (2005) Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma. Int J Mol Med 15:337-352
    • (2005) Int J Mol Med , vol.15 , pp. 337-352
    • Baatout, S.1    Derradji, H.2    Jacquet, P.3    Mergeay, M.4
  • 61
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal BB, Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 71:1397-1421
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 62
    • 51549087131 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by green tea polyphenols
    • Khan N, Mukhtar H (2008) Multitargeted therapy of cancer by green tea polyphenols. Cancer Lett 269:269-280
    • (2008) Cancer Lett , vol.269 , pp. 269-280
    • Khan, N.1    Mukhtar, H.2
  • 63
    • 69049087664 scopus 로고    scopus 로고
    • Cellular signaling perturbation by natural products
    • Sarkar FH, Li Y, Wang Z, Kong D (2009) Cellular signaling perturbation by natural products. Cell Signal 21:1541-1547
    • (2009) Cell Signal , vol.21 , pp. 1541-1547
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 64
    • 0141863400 scopus 로고    scopus 로고
    • Mechanisms of cancer prevention by tea constituents
    • Lambert JD, Yang CS (2003) Mechanisms of cancer prevention by tea constituents. J Nutr 133:3262S-3267S
    • (2003) J Nutr , vol.133
    • Lambert, J.D.1    Yang, C.S.2
  • 65
    • 0027058940 scopus 로고
    • The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element
    • Miner JN, Yamamoto KR (1992) The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element. Gene Dev 6:2491-2501
    • (1992) Gene Dev , vol.6 , pp. 2491-2501
    • Miner, J.N.1    Yamamoto, K.R.2
  • 66
    • 33744976109 scopus 로고    scopus 로고
    • Molecular targets for the cancer preventive activity of tea polyphenols
    • Yang CS, Lambert JD, Hou Z, Ju J, Lu G, Hao X (2006) Molecular targets for the cancer preventive activity of tea polyphenols. Mol Carcinog 45:431-435
    • (2006) Mol Carcinog , vol.45 , pp. 431-435
    • Yang, C.S.1    Lambert, J.D.2    Hou, Z.3    Ju, J.4    Lu, G.5    Hao, X.6
  • 68
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • Samani AA, Yakar S, LeRoith D, Brodt P (2007) The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 28:20-47
    • (2007) Endocr Rev , vol.28 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    Leroith, D.3    Brodt, P.4
  • 69
    • 33644637252 scopus 로고    scopus 로고
    • Possible mechanisms of the cancer-preventive activities of green tea
    • Yang CS, Sang S, Lambert JD, Hou Z, Ju J, Lu G (2006) Possible mechanisms of the cancer-preventive activities of green tea. Mol Nutr Food Res 50:170-175
    • (2006) Mol Nutr Food Res , vol.50 , pp. 170-175
    • Yang, C.S.1    Sang, S.2    Lambert, J.D.3    Hou, Z.4    Ju, J.5    Lu, G.6
  • 70
    • 0033568515 scopus 로고    scopus 로고
    • Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells structure-Activity relationship and mechanisms involved
    • Chung JY, Huang C, Meng X, Dong Z, Yang CS (1999) Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells structure-Activity relationship and mechanisms involved. Cancer Res 59:4610-4617
    • (1999) Cancer Res , vol.59 , pp. 4610-4617
    • Chung, J.Y.1    Huang, C.2    Meng, X.3    Dong, Z.4    Yang, C.S.5
  • 71
    • 0036428820 scopus 로고    scopus 로고
    • Synthetic analogs of green tea polyphenols as proteasome inhibitors
    • Smith DM, Wang Z, Kazi A, Li L-H, Chan T-H, Dou QP (2002) Synthetic analogs of green tea polyphenols as proteasome inhibitors. Mol Med 8:382-392
    • (2002) Mol Med , vol.8 , pp. 382-392
    • Smith, D.M.1    Wang, Z.2    Kazi, A.3    Li, L.-H.4    Chan, T.-H.5    Dou, Q.P.6
  • 72
    • 0034909129 scopus 로고    scopus 로고
    • A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    • Gusman J, Malonne H, Atassi G (2001) A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis 22:1111-1117
    • (2001) Carcinogenesis , vol.22 , pp. 1111-1117
    • Gusman, J.1    Malonne, H.2    Atassi, G.3
  • 73
    • 0345862319 scopus 로고    scopus 로고
    • Nutraceuticals, apoptosis, and disease prevention
    • Gosslau A, Chen KY (2004) Nutraceuticals, apoptosis, and disease prevention. Nutrition 20:95-102
    • (2004) Nutrition , vol.20 , pp. 95-102
    • Gosslau, A.1    Chen, K.Y.2
  • 74
    • 0037126058 scopus 로고    scopus 로고
    • Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice
    • Lu YP, Lou YR, Xie JG, Peng QY, Liao J, Yang CS et al (2002) Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice. P Natl Acad Sci USA 99:12455-12460
    • (2002) P Natl Acad Sci USA , vol.99 , pp. 12455-12460
    • Lu, Y.P.1    Lou, Y.R.2    Xie, J.G.3    Peng, Q.Y.4    Liao, J.5    Yang, C.S.6
  • 75
    • 3242703539 scopus 로고    scopus 로고
    • VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia
    • Lee YK, Bone ND, Strege AK, Shanafelt TD, Jelinek DF, Kay NE (2004) VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia. Blood 104:788-794
    • (2004) Blood , vol.104 , pp. 788-794
    • Lee, Y.K.1    Bone, N.D.2    Strege, A.K.3    Shanafelt, T.D.4    Jelinek, D.F.5    Kay, N.E.6
  • 76
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO (2000) The biochemistry of apoptosis. Nature 407:770-776
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 78
    • 0033613143 scopus 로고    scopus 로고
    • Caspase activation: The inducedproximity model
    • Salvesen GS, Dixit VM (1999) Caspase activation: the inducedproximity model. P Natl Acad Sci USA 96:10964-10967
    • (1999) P Natl Acad Sci USA , vol.96 , pp. 10964-10967
    • Salvesen, G.S.1    Dixit, V.M.2
  • 79
    • 33846821868 scopus 로고    scopus 로고
    • A component of green tea, (-)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins
    • Qin J, Xie LP, Zheng XY, Wang YB, Bai Y, Shen HF et al (2007) A component of green tea, (-)-epigallocatechin-3-gallate, promotes apoptosis in T24 human bladder cancer cells via modulation of the PI3K/Akt pathway and Bcl-2 family proteins. Biochem Bioph Res Co 354:852-857
    • (2007) Biochem Bioph Res Co , vol.354 , pp. 852-857
    • Qin, J.1    Xie, L.P.2    Zheng, X.Y.3    Wang, Y.B.4    Bai, Y.5    Shen, H.F.6
  • 80
    • 1942532874 scopus 로고    scopus 로고
    • Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis
    • Gupta S, Hastak K, Afaq F, Ahmad N, Mukhtar H (2004) Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. Oncogene 23:2507-2522
    • (2004) Oncogene , vol.23 , pp. 2507-2522
    • Gupta, S.1    Hastak, K.2    Afaq, F.3    Ahmad, N.4    Mukhtar, H.5
  • 81
    • 0041337028 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells
    • Brusselmans K, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV (2003) Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells. Int J Cancer 106:856-862
    • (2003) Int J Cancer , vol.106 , pp. 856-862
    • Brusselmans, K.1    De Schrijver, E.2    Heyns, W.3    Verhoeven, G.4    Swinnen, J.V.5
  • 82
    • 41149143243 scopus 로고    scopus 로고
    • Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis
    • Siddiqui IA, Malik A, Adhami VM, Asim M, Hafeez BB, Sarfaraz S et al (2008) Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis. Oncogene 27:2055-2063
    • (2008) Oncogene , vol.27 , pp. 2055-2063
    • Siddiqui, I.A.1    Malik, A.2    Adhami, V.M.3    Asim, M.4    Hafeez, B.B.5    Sarfaraz, S.6
  • 83
    • 13944278899 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation
    • Roy AM, Baliga MS, Katiyar SK (2005) Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation. Mol Cancer Ther 4:81-90
    • (2005) Mol Cancer Ther , vol.4 , pp. 81-90
    • Roy, A.M.1    Baliga, M.S.2    Katiyar, S.K.3
  • 84
    • 41749102898 scopus 로고    scopus 로고
    • Inhibition of pi3k/ akt and mek/erk pathways act synergistically to enhance antiangiogenic effects of egcg through activation of foxo transcription factor
    • Shankar S, Chen Q, Srivastava RK (2008) Inhibition of PI3K/ AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor. J Mol Signal 3:7
    • (2008) J Mol Signal , vol.3 , pp. 7
    • Shankar, S.1    Chen, Q.2    Srivastava, R.K.3
  • 85
    • 33846474121 scopus 로고    scopus 로고
    • G-protein-coupled receptors and cancer
    • Dorsam RT, Gutkind JS (2007) G-protein-coupled receptors and cancer. Nat Rev Cancer 7:79-94
    • (2007) Nat Rev Cancer , vol.7 , pp. 79-94
    • Dorsam, R.T.1    Gutkind, J.S.2
  • 86
    • 0035682310 scopus 로고    scopus 로고
    • Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea
    • Jung YD, Ellis LM (2001) Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol 82:309-316
    • (2001) Int J Exp Pathol , vol.82 , pp. 309-316
    • Jung, Y.D.1    Ellis, L.M.2
  • 87
    • 2542421799 scopus 로고    scopus 로고
    • Epigallocatechin gallate inhibits membranetype 1 matrix metalloproteinase MT1-MMP, and tumor angiogenesis
    • Yamakawa S, Asai T, Uchida T, Matsukawa M, Akizawa T, Oku N (2004) (-)-Epigallocatechin gallate inhibits membranetype 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis. Cancer Lett 210:47-55
    • (2004) Cancer Lett , vol.210 , pp. 47-55
    • Yamakawa, S.1    Asai, T.2    Uchida, T.3    Matsukawa, M.4    Akizawa, T.5    Oku, N.6
  • 88
    • 77957590316 scopus 로고    scopus 로고
    • Cancer and metastasis: Prevention and treatment by green tea
    • Khan N, Mukhtar H (2010) Cancer and metastasis: prevention and treatment by green tea. Cancer Metast Rev 29:435-445
    • (2010) Cancer Metast Rev , vol.29 , pp. 435-445
    • Khan, N.1    Mukhtar, H.2
  • 90
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2:161-174
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 91
    • 33645320220 scopus 로고    scopus 로고
    • The green tea catechins, -)-epigallocatechin-3-gallate (EGCG) and (-)-epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells
    • Bigelow R, Cardelli J (2006) The green tea catechins,(-)- epigallocatechin-3-gallate (EGCG) and (-)-epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells. Oncogene 25:1922-1930
    • (2006) Oncogene , vol.25 , pp. 1922-1930
    • Bigelow, R.1    Cardelli, J.2
  • 92
    • 0035829013 scopus 로고    scopus 로고
    • Inhibitory effect of epigallocatechin gallate on adhesion of murine melanoma cells to laminin
    • Suzuki Y, Isemura M (2001) Inhibitory effect of epigallocatechin gallate on adhesion of murine melanoma cells to laminin. Cancer letters 173:15-20
    • (2001) Cancer Letters , vol.173 , pp. 15-20
    • Suzuki, Y.1    Isemura, M.2
  • 93
    • 50149087741 scopus 로고    scopus 로고
    • EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase
    • Punathil T, Tollefsbol TO, Katiyar SK (2008) EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase. Biochem Biophys Res Co 375:162-167
    • (2008) Biochem Biophys Res Co , vol.375 , pp. 162-167
    • Punathil, T.1    Tollefsbol, T.O.2    Katiyar, S.K.3
  • 94
    • 34248363654 scopus 로고    scopus 로고
    • Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells
    • Tang FY, Chiang EP, Shih CJ (2007) Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells. J Nutr Biochem 18:391-399
    • (2007) J Nutr Biochem , vol.18 , pp. 391-399
    • Tang, F.Y.1    Chiang, E.P.2    Shih, C.J.3
  • 95
    • 3242664189 scopus 로고    scopus 로고
    • Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate
    • Fassina G, Vene R, Morini M, Minghelli S, Benelli R, Noonan DM et al (2004) Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin Cancer Res 10:4865-4873
    • (2004) Clin Cancer Res , vol.10 , pp. 4865-4873
    • Fassina, G.1    Vene, R.2    Morini, M.3    Minghelli, S.4    Benelli, R.5    Noonan, D.M.6
  • 96
    • 0037081274 scopus 로고    scopus 로고
    • Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation
    • Lamy S, Gingras D, Beliveau R (2002) Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. Cancer Res 62:381-385
    • (2002) Cancer Res , vol.62 , pp. 381-385
    • Lamy, S.1    Gingras, D.2    Beliveau, R.3
  • 97
    • 0037189026 scopus 로고    scopus 로고
    • Tea catechins inhibit angiogenesis in vitro, measured by human endothelial cell growth, migration and tube formation, through inhibition of VEGF receptor binding
    • Kondo T, Ohta T, Igura K, Hara Y, Kaji K (2002) Tea catechins inhibit angiogenesis in vitro, measured by human endothelial cell growth, migration and tube formation, through inhibition of VEGF receptor binding. Cancer Lett 180:139-144
    • (2002) Cancer Lett , vol.180 , pp. 139-144
    • Kondo, T.1    Ohta, T.2    Igura, K.3    Hara, Y.4    Kaji, K.5
  • 98
    • 55449105561 scopus 로고    scopus 로고
    • The modulation of endothelial cell gene expression by green tea polyphenol-EGCG
    • Liu L, Lai CQ, Nie L, Ordovas J, Band M, Moser L et al (2008) The modulation of endothelial cell gene expression by green tea polyphenol-EGCG. Mol Nutr Food Res 52:1182-1192
    • (2008) Mol Nutr Food Res , vol.52 , pp. 1182-1192
    • Liu, L.1    Lai, C.Q.2    Nie, L.3    Ordovas, J.4    Band, M.5    Moser, L.6
  • 99
    • 79957870537 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 via Stat3 in gastric cancer
    • Zhu BH, Chen HY, Zhan WH, Wang CY, Cai SR, Wang Z et al (2011) (-)-Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 via Stat3 in gastric cancer. WJG 17:2315-2325
    • (2011) WJG , vol.17 , pp. 2315-2325
    • Zhu, B.H.1    Chen, H.Y.2    Zhan, W.H.3    Wang, C.Y.4    Cai, S.R.5    Wang, Z.6
  • 100
    • 0035527489 scopus 로고    scopus 로고
    • Green tea catechins and vitamin e inhibit angiogenesis of human microvascular endothelial cells through suppression of IL-8 production
    • Tang FY, Meydani M (2001) Green tea catechins and vitamin E inhibit angiogenesis of human microvascular endothelial cells through suppression of IL-8 production. Nutr Cancer 41:119-125
    • (2001) Nutr Cancer , vol.41 , pp. 119-125
    • Tang, F.Y.1    Meydani, M.2
  • 101
    • 84862318675 scopus 로고    scopus 로고
    • Cancer stem cells: Potential target for bioactive food components
    • Kim YS, Farrar W, Colburn NH, Milner JA (2012) Cancer stem cells: potential target for bioactive food components. J Nutr Biochem 23:691-698
    • (2012) J Nutr Biochem , vol.23 , pp. 691-698
    • Kim, Y.S.1    Farrar, W.2    Colburn, N.H.3    Milner, J.A.4
  • 102
    • 79958160079 scopus 로고    scopus 로고
    • Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds
    • Li Y, Wicha MS, Schwartz SJ, Sun D (2011) Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. J Nutr Biochem 22:799-806
    • (2011) J Nutr Biochem , vol.22 , pp. 799-806
    • Li, Y.1    Wicha, M.S.2    Schwartz, S.J.3    Sun, D.4
  • 103
    • 77955641868 scopus 로고    scopus 로고
    • The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
    • Tang S-N, Singh C, Nall D, Meeker D, Shankar S, Srivastava RK (2010) The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition. J Mol Signal 5:14
    • (2010) J Mol Signal , vol.5 , pp. 14
    • Tang, S.-N.1    Singh, C.2    Nall, D.3    Meeker, D.4    Shankar, S.5    Srivastava, R.K.6
  • 104
    • 79957989939 scopus 로고    scopus 로고
    • Drug discovery approaches to target Wnt signaling in cancer stem cells
    • Curtin JC, Lorenzi MV (2010) Drug discovery approaches to target Wnt signaling in cancer stem cells. Oncotarget 1:552
    • (2010) Oncotarget , vol.1 , pp. 552
    • Curtin, J.C.1    Lorenzi, M.V.2
  • 105
    • 68949194441 scopus 로고    scopus 로고
    • Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail
    • Bode AM, Dong Z (2009) Epigallocatechin 3-gallate and green tea catechins: united they work, divided they fail. Cancer Prev Res 2:514-517
    • (2009) Cancer Prev Res , vol.2 , pp. 514-517
    • Bode, A.M.1    Dong, Z.2
  • 106
    • 79952081301 scopus 로고    scopus 로고
    • New cancer treatment strategy using combination of green tea catechins and anticancer drugs
    • Suganuma M, Saha A, Fujiki H (2011) New cancer treatment strategy using combination of green tea catechins and anticancer drugs. Cancer Sci 102:317-323
    • (2011) Cancer Sci , vol.102 , pp. 317-323
    • Suganuma, M.1    Saha, A.2    Fujiki, H.3
  • 107
    • 53049096668 scopus 로고    scopus 로고
    • A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate
    • Scandlyn M, Stuart E, Somers-Edgar T, Menzies A, Rosengren R (2008) A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate. BRIT J Cancer 99:1056-1063
    • (2008) BRIT J Cancer , vol.99 , pp. 1056-1063
    • Scandlyn, M.1    Stuart, E.2    Somers-Edgar, T.3    Menzies, A.4    Rosengren, R.5
  • 109
    • 9344257283 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis
    • Boolbol SK, Dannenberg AJ, Chadburn A, Martucci C, Guo XJ, Ramonetti JT et al (1996) Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Cancer Res 56:2556-2560
    • (1996) Cancer Res , vol.56 , pp. 2556-2560
    • Boolbol, S.K.1    Dannenberg, A.J.2    Chadburn, A.3    Martucci, C.4    Guo, X.J.5    Ramonetti, J.T.6
  • 110
    • 0036177847 scopus 로고    scopus 로고
    • Long-term treatment with sulindac in familial adenomatous polyposis: A prospective cohort study
    • Cruz-Correa M, Hylind LM, Romans KE, Booker SV, Giardiello FM (2002) Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Gastroenterology 122:641-645
    • (2002) Gastroenterology , vol.122 , pp. 641-645
    • Cruz-Correa, M.1    Hylind, L.M.2    Romans, K.E.3    Booker, S.V.4    Giardiello, F.M.5
  • 111
    • 0037292963 scopus 로고    scopus 로고
    • New TNF-A releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen
    • Fujiki H, Suganuma M, Kurusu M, Okabe S, Imayoshi Y, Taniguchi S et al (2003) New TNF-A releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen. Mutat Res-Fund Mol M 523:119-125
    • (2003) Mutat Res-Fund Mol M , vol.523 , pp. 119-125
    • Fujiki, H.1    Suganuma, M.2    Kurusu, M.3    Okabe, S.4    Imayoshi, Y.5    Taniguchi, S.6
  • 114
    • 33646521308 scopus 로고    scopus 로고
    • Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene
    • Suganuma M, Kurusu M, Suzuki K, Tasaki E, Fujiki H (2006) Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene. Int J Cancer 119:33-40
    • (2006) Int J Cancer , vol.119 , pp. 33-40
    • Suganuma, M.1    Kurusu, M.2    Suzuki, K.3    Tasaki, E.4    Fujiki, H.5
  • 115
  • 116
    • 0031927214 scopus 로고    scopus 로고
    • Quantitation of chemopreventive synergism between (-)-epigallocatechin-3- gallate and curcumin in normal, premalignant and malignant human oral epithelial cells
    • Khafif A, Schantz SP, Chou TC, Edelstein D, Sacks PG (1998) Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. Carcinogenesis 19:419-424
    • (1998) Carcinogenesis , vol.19 , pp. 419-424
    • Khafif, A.1    Schantz, S.P.2    Chou, T.C.3    Edelstein, D.4    Sacks, P.G.5
  • 117
    • 68949173809 scopus 로고    scopus 로고
    • Synergistic growth inhibition of squamous cell carcinoma of the head and neck by erlotinib and epigallocatechin-3-gallate: The role of p53-dependent inhibition of nuclear factor-jB
    • Amin AR, Khuri FR, Shin DM (2009) Synergistic growth inhibition of squamous cell carcinoma of the head and neck by erlotinib and epigallocatechin-3-gallate: the role of p53-dependent inhibition of nuclear factor-jB. Cancer Prev Res 2:538-545
    • (2009) Cancer Prev Res , vol.2 , pp. 538-545
    • Amin, A.R.1    Khuri, F.R.2    Shin, D.M.3
  • 118
    • 24744471877 scopus 로고    scopus 로고
    • Mechanism of action of (-)-epigallocatechin-3-gallate: Autooxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells
    • Hou Z, Sang S, You H, Lee MJ, Hong J, Chin KV et al (2005) Mechanism of action of (-)-epigallocatechin-3-gallate: autooxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells. Cancer Res 65:8049-8056
    • (2005) Cancer Res , vol.65 , pp. 8049-8056
    • Hou, Z.1    Sang, S.2    You, H.3    Lee, M.J.4    Hong, J.5    Chin, K.V.6
  • 119
    • 33845789994 scopus 로고    scopus 로고
    • Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway
    • Hwang JT, Ha J, Park IJ, Lee SK, Baik HW, Kim YM et al (2007) Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway. Cancer Lett 247:115-121
    • (2007) Cancer Lett , vol.247 , pp. 115-121
    • Hwang, J.T.1    Ha, J.2    Park, I.J.3    Lee, S.K.4    Baik, H.W.5    Kim, Y.M.6
  • 120
    • 84873992343 scopus 로고    scopus 로고
    • Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation
    • Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO (2013) Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation. Exp Cell Res 319:697-706
    • (2013) Exp Cell Res , vol.319 , pp. 697-706
    • Chen, H.1    Landen, C.N.2    Li, Y.3    Alvarez, R.D.4    Tollefsbol, T.O.5
  • 121
    • 77956038678 scopus 로고    scopus 로고
    • Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma
    • doi:10.1186/bcr2473
    • Luo T, Wang J, Yin Y, Hua H, Jing J, Sun X et al (2010) (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma. Breast Cancer Res. doi:10.1186/bcr2473
    • (2010) Breast Cancer Res
    • Luo, T.1    Wang, J.2    Yin, Y.3    Hua, H.4    Jing, J.5    Sun, X.6
  • 122
    • 33845964413 scopus 로고    scopus 로고
    • Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate
    • Kweon MH, Adhami VM, Lee JS, Mukhtar H (2006) Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate. J Biol Chem 281:33761-33772
    • (2006) J Biol Chem , vol.281 , pp. 33761-33772
    • Kweon, M.H.1    Adhami, V.M.2    Lee, J.S.3    Mukhtar, H.4
  • 123
    • 0037163110 scopus 로고    scopus 로고
    • Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y, Amit T, Youdim MBH, Mandel S (2002) Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J Biol Chem 277:30574-30580
    • (2002) J Biol Chem , vol.277 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Mbh, Y.3    Mandel, S.4
  • 125
    • 77957602526 scopus 로고    scopus 로고
    • Micronutrient synergy-A new tool in effective control of metastasis and other key mechanisms of cancer
    • Niedzwiecki A, Roomi MW, Kalinovsky T, Rath M (2010) Micronutrient synergy-A new tool in effective control of metastasis and other key mechanisms of cancer. Cancer Metast Rev 29:529-542
    • (2010) Cancer Metast Rev , vol.29 , pp. 529-542
    • Niedzwiecki, A.1    Roomi, M.W.2    Kalinovsky, T.3    Rath, M.4
  • 126
    • 35348855249 scopus 로고    scopus 로고
    • Keratinocyte proliferation, differentiation, and apoptosis-differential mechanisms of regulation by curcumin, EGCG and apigenin
    • Balasubramanian S, Eckert RL (2007) Keratinocyte proliferation, differentiation, and apoptosis-differential mechanisms of regulation by curcumin, EGCG and apigenin. Toxicol Appl Pharm 224:214-219
    • (2007) Toxicol Appl Pharm , vol.224 , pp. 214-219
    • Balasubramanian, S.1    Eckert, R.L.2
  • 127
    • 33845357645 scopus 로고    scopus 로고
    • Epigallocatechin gallate induced apoptosis in Sarcoma180 cells in vivo: Mediated by p53 pathway and inhibition in U1B U4-U6 UsnRNAs expression
    • Manna S, Banerjee S, Mukherjee S, Das S, Panda CK (2006) Epigallocatechin gallate induced apoptosis in Sarcoma180 cells in vivo: mediated by p53 pathway and inhibition in U1B, U4-U6 UsnRNAs expression. Apoptosis 11:2267-2276
    • (2006) Apoptosis , vol.11 , pp. 2267-2276
    • Manna, S.1    Banerjee, S.2    Mukherjee, S.3    Das, S.4    Panda, C.K.5
  • 128
    • 34247136212 scopus 로고    scopus 로고
    • Green tea and skin cancer: Photoimmunology, angiogenesis and DNA repair
    • Katiyar S, Elmets CA, Katiyar SK (2007) Green tea and skin cancer: photoimmunology, angiogenesis and DNA repair. J Nutr Biochem 18:287-296
    • (2007) J Nutr Biochem , vol.18 , pp. 287-296
    • Katiyar, S.1    Elmets, C.A.2    Katiyar, S.K.3
  • 129
    • 0034495023 scopus 로고    scopus 로고
    • Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-A expression
    • Suganuma M, Sueoka E, Sueoka N, Okabe S, Fujiki H (2000) Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-A expression. Biofactors 13:67-72
    • (2000) Biofactors , vol.13 , pp. 67-72
    • Suganuma, M.1    Sueoka, E.2    Sueoka, N.3    Okabe, S.4    Fujiki, H.5
  • 130
    • 0037040434 scopus 로고    scopus 로고
    • Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane
    • Ohishi T, Kishimoto Y, Miura N, Shiota G, Kohri T, Hara Y et al (2002) Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane. Cancer Lett 177:49-56
    • (2002) Cancer Lett , vol.177 , pp. 49-56
    • Ohishi, T.1    Kishimoto, Y.2    Miura, N.3    Shiota, G.4    Kohri, T.5    Hara, Y.6
  • 131
    • 84891917085 scopus 로고    scopus 로고
    • Pancreatic cancer chemoprevention by phytochemicals
    • Boreddy SR, Srivastava SK (2012) Pancreatic cancer chemoprevention by phytochemicals. Cancer Lett 334:86-94
    • (2012) Cancer Lett , vol.334 , pp. 86-94
    • Boreddy, S.R.1    Srivastava, S.K.2
  • 132
    • 84863003468 scopus 로고    scopus 로고
    • Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway
    • Ha J, Zhao L, Zhao Q, Yao J, Zhu BB, Lu N et al (2012) Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway. Biochem Cell Biol 90:521-531
    • (2012) Biochem Cell Biol , vol.90 , pp. 521-531
    • Ha, J.1    Zhao, L.2    Zhao, Q.3    Yao, J.4    Zhu, B.B.5    Lu, N.6
  • 133
    • 0031907021 scopus 로고    scopus 로고
    • Modulation of cancer chemotherapy by green tea
    • Sadzuka Y, Sugiyama T, Hirota S (1998) Modulation of cancer chemotherapy by green tea. Clin Cancer Res 4:153-156
    • (1998) Clin Cancer Res , vol.4 , pp. 153-156
    • Sadzuka, Y.1    Sugiyama, T.2    Hirota, S.3
  • 134
    • 84866436804 scopus 로고    scopus 로고
    • Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2
    • Chang CM, Chang PY, Tu MG, Lu CC, Kuo SC, Amagaya S et al (2012) Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2. Oncol Rep 28:1799-1807
    • (2012) Oncol Rep , vol.28 , pp. 1799-1807
    • Chang, C.M.1    Chang, P.Y.2    Tu, M.G.3    Lu, C.C.4    Kuo, S.C.5    Amagaya, S.6
  • 135
    • 0030930265 scopus 로고    scopus 로고
    • Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells
    • Liang Y-C, Lin-Shiau S-Y, Chen C-F, Lin J-K (1997) Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J Cell Biochem 67:55-65
    • (1997) J Cell Biochem , vol.67 , pp. 55-65
    • Liang, Y.-C.1    Lin-Shiau, S.-Y.2    Chen, C.-F.3    Lin, J.-K.4
  • 136
    • 33745627071 scopus 로고    scopus 로고
    • Green tea, black tea and breast cancer risk: A meta-Analysis of epidemiological studies
    • Sun C-L, Yuan J-M, Koh W-P, Mimi CY (2006) Green tea, black tea and breast cancer risk: a meta-Analysis of epidemiological studies. Carcinogenesis 27:1310-1315
    • (2006) Carcinogenesis , vol.27 , pp. 1310-1315
    • Sun, C.-L.1    Yuan, J.-M.2    Koh, W.-P.3    Mimi, C.Y.4
  • 137
    • 0034494832 scopus 로고    scopus 로고
    • Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention
    • Nakachi K, Matsuyama S, Miyake S, Suganuma M, Imai K (2000) Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention. Biofactors 13:49-54
    • (2000) Biofactors , vol.13 , pp. 49-54
    • Nakachi, K.1    Matsuyama, S.2    Miyake, S.3    Suganuma, M.4    Imai, K.5
  • 139
    • 0030689057 scopus 로고    scopus 로고
    • Cancer-preventive effects of drinking green tea among a Japanese population
    • Imai K, Suga K, Nakachi K (1997) Cancer-preventive effects of drinking green tea among a Japanese population. Prev Med 26:769
    • (1997) Prev Med , vol.26 , pp. 769
    • Imai, K.1    Suga, K.2    Nakachi, K.3
  • 140
    • 84866145433 scopus 로고    scopus 로고
    • Phase IB randomized, double-blinded, placebocontrolled, dose escalation study of polyphenon e in women with hormone receptor-negative breast cancer
    • Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C et al (2012) Phase IB randomized, double-blinded, placebocontrolled, dose escalation study of polyphenon e in women with hormone receptor-negative breast cancer. Cancer Prev Res 5:1144-1154
    • (2012) Cancer Prev Res , vol.5 , pp. 1144-1154
    • Crew, K.D.1    Brown, P.2    Greenlee, H.3    Bevers, T.B.4    Arun, B.5    Hudis, C.6
  • 142
    • 84872058507 scopus 로고    scopus 로고
    • Phase 2 trial of daily, oral polyphenon e in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia
    • Shanafelt TD, Call TG, Zent CS, Leis JF, LaPlant B, Bowen DA et al (2012) Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer 119(2):363-370
    • (2012) Cancer , vol.119 , Issue.2 , pp. 363-370
    • Shanafelt, T.D.1    Call, T.G.2    Zent, C.S.3    Leis, J.F.4    Laplant, B.5    Bowen, D.A.6
  • 143
    • 2542520785 scopus 로고    scopus 로고
    • Green tea polyphenols and cancer chemoprevention: Multiple mechanisms and endpoints for phase II trials
    • Moyers SB, Kumar NB (2004) Green tea polyphenols and cancer chemoprevention: multiple mechanisms and endpoints for phase II trials. Nutr Rev 62:204-211
    • (2004) Nutr Rev , vol.62 , pp. 204-211
    • Moyers, S.B.1    Kumar, N.B.2
  • 144
    • 0034608780 scopus 로고    scopus 로고
    • Green tea experiments in lab, clinic yield mixed results
    • Webb T (2000) Green tea experiments in lab, clinic yield mixed results. J Natl Cancer I 92:1038-1039
    • (2000) J Natl Cancer i , vol.92 , pp. 1038-1039
    • Webb, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.