Impaired autophagic function in rat islets with aging

Age

Volumn 35, Issue 5, 2013, Pages 1531-1544

  Liu, Yu ^a   Shi, Suozhu ^a   Gu, Zhaoyan ^a   Du, Yingzhen ^a   Liu, Minyan ^a   Yan, Shuangtong ^a   Gao, Jianjun ^a   Li, Jian ^a   Shao, Yinghong ^a   Zhong, Wenwen ^a   Chen, Xiangmei ^a   Li, Chunlin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Aging; Autophagy; Islet; Mitochondria; Oxidative damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BECLIN 1; GLUCOSE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYUBIQUITIN; PROTEIN ATG14; PROTEIN ATG7; PROTEIN ATG8; PROTEIN P62; PROTEIN SERINE THREONINE KINASE VPS15; UNCLASSIFIED DRUG;

ADULT; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; GLUCOSE BLOOD LEVEL; MALE; MITOCHONDRION SWELLING; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PROTEIN AGGREGATION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

AGING; ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DISEASE PROGRESSION; IMMUNOHISTOCHEMISTRY; INSULIN-SECRETING CELLS; MALE; MICROSCOPY, ELECTRON; MICROTUBULE-ASSOCIATED PROTEINS; RATS; RATS, WISTAR; UBIQUITIN-ACTIVATING ENZYMES;

EID: 84892608397     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-012-9456-0     Document Type: Article

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