Effect of aging on islet beta-cell function and its mechanisms in Wistar rats

Age

Volumn 34, Issue 6, 2012, Pages 1393-1403

  Gu, Zhaoyan ^a   Du, Yingzhen ^a   Liu, Yu ^a   Ma, Lichao ^a   Li, Lin ^a   Gong, Yanping ^a   Tian, Hui ^a   Li, Chunlin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Aging; Insulin resistance; Islet secretion function; Rats

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUCOSE; GLUTATHIONE PEROXIDASE; LIPOCORTIN 1; MALONALDEHYDE; PALMITIC ACID; SUPEROXIDE DISMUTASE; CYCLINE; MESSENGER RNA;

AGE DISTRIBUTION; AGING; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE INTOLERANCE; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; CELL CULTURE; DNA MICROARRAY; GENE EXPRESSION; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPERINSULINISM; INSULIN RESISTANCE; METABOLISM; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

AGING; ANIMALS; ANNEXIN A1; APOPTOSIS; BLOOD GLUCOSE; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; HYPERINSULINISM; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84876485595     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9312-7     Document Type: Article

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