Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients

Diabetologia

Volumn 56, Issue 5, 2013, Pages 1068-1077

  Caton, P W ^a   Richardson, S J ^b   Kieswich, J ^a   Bugliani, M ^c   Holland, M L ^a   Marchetti, P ^c   Morgan, N G ^b   Yaqoob, M M ^a   Holness, M J ^a   Sugden, M C ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

Beta cell; Pancreatic islets; SIRT3

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; DIABETIC PATIENT; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION;

AGED; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; CELL LINE; CYTOKINES; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; RATS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIRTUIN 3; TISSUE CULTURE TECHNIQUES;

EID: 84876502959     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2851-y     Document Type: Article

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