메뉴 건너뛰기




Volumn 43, Issue 1, 2014, Pages 82-91

Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; CARBON MONOXIDE; CATHEPSIN L; CATHEPSIN S; CYSTATIN C; GELATINASE B; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MESSENGER RNA; PROTEINASE; PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

EID: 84891910656     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00174612     Document Type: Review
Times cited : (43)

References (58)
  • 1
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality disability by cause 1990-2020: Global burden of disease study
    • Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997; 349: 1498-1504.
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 0034948984 scopus 로고    scopus 로고
    • Epidemiology of chronic obstructive pulmonary disease
    • Antó JM, Vermeire P, Vestbo J, et al. Epidemiology of chronic obstructive pulmonary disease. Eur Respir J 2001; 17: 982-994.
    • (2001) Eur Respir J , vol.17 , pp. 982-994
    • Antó, J.M.1    Vermeire, P.2    Vestbo, J.3
  • 3
    • 0035888763 scopus 로고    scopus 로고
    • Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction
    • McCloskey SC, Patel BD, Hinchliffe SJ, et al. Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction. Am J Respir Crit Care Med 2001; 164: 1419-1424.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1419-1424
    • McCloskey, S.C.1    Patel, B.D.2    Hinchliffe, S.J.3
  • 4
    • 0036729605 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease - Part 2: Pathology and biochemistry of emphysema
    • Hogg JC, Senior RM. Chronic obstructive pulmonary disease - part 2: Pathology and biochemistry of emphysema. Thorax 2002; 57: 830-834.
    • (2002) Thorax , vol.57 , pp. 830-834
    • Hogg, J.C.1    Senior, R.M.2
  • 5
    • 0033618337 scopus 로고    scopus 로고
    • Matrix metalloproteinases
    • Nagase H, Woessner JF. Matrix metalloproteinases. J Biol Chem 1999; 274: 21491-21494.
    • (1999) J Biol Chem , vol.274 , pp. 21491-21494
    • Nagase, H.1    Woessner, J.F.2
  • 6
    • 0032698544 scopus 로고    scopus 로고
    • The macrophage in chronic obstructive pulmonary disease
    • Shapiro SD. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: S29-S32.
    • (1999) Am J Respir Crit Care Med , vol.160
    • Shapiro, S.D.1
  • 7
    • 84855413331 scopus 로고    scopus 로고
    • Metalloproteasesanti-metalloproteases imbalance in chronic obstructive pulmonary disease genetic factors treatment implications
    • Mocchegiani E, Giacconi R, Costarelli L. Metalloproteases/anti- metalloproteases imbalance in chronic obstructive pulmonary disease: Genetic factors and treatment implications. Curr Opin Pulm Med 2011; 17: Suppl. 1, S11-S19.
    • (2011) Curr Opin Pulm Med , vol.17 , Issue.SUPPL. 1
    • Mocchegiani, E.1    Giacconi, R.2    Costarelli, L.3
  • 8
    • 0030970119 scopus 로고    scopus 로고
    • Emerging roles for cysteine proteases in human biology
    • Chapman HA, Riese RJ, Shi GP. Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 1997; 59: 63-88.
    • (1997) Annu Rev Physiol , vol.59 , pp. 63-88
    • Chapman, H.A.1    Riese, R.J.2    Shi, G.P.3
  • 9
    • 0035744614 scopus 로고    scopus 로고
    • Cytokines in chronic obstructive pulmonary disease
    • Chung KF. Cytokines in chronic obstructive pulmonary disease. Eur Respir J 2001; 18: Suppl. 34, 50s-59s.
    • (2001) Eur Respir J , vol.18 , Issue.SUPPL. 34
    • Chung, K.F.1
  • 10
    • 0034960964 scopus 로고    scopus 로고
    • Bacteria, antibiotics and COPD
    • Wilson R. Bacteria, antibiotics and COPD. Eur Respir J 2001; 17: 995-1007.
    • (2001) Eur Respir J , vol.17 , pp. 995-1007
    • Wilson, R.1
  • 11
    • 38949189965 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema
    • Wallace AM, Sandford AJ, English JC, et al. Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema. COPD 2008; 5: 13-23.
    • (2008) COPD , vol.5 , pp. 13-23
    • Wallace, A.M.1    Sandford, A.J.2    English, J.C.3
  • 12
    • 0029442272 scopus 로고
    • Single-breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique - 1995 update
    • American Thoracic Society
    • American Thoracic Society. Single-breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique - 1995 update. Am J Respir Crit Care Med 1995; 152: 2185-2198.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 2185-2198
  • 13
    • 0036501372 scopus 로고    scopus 로고
    • The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function
    • Joos L, He JQ, Shepherdson MB, et al. The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum Mol Genet 2002; 11: 569-576.
    • (2002) Hum Mol Genet , vol.11 , pp. 569-576
    • Joos, L.1    He, J.Q.2    Shepherdson, M.B.3
  • 14
    • 0035941048 scopus 로고    scopus 로고
    • Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema
    • Minematsu N, Nakamura H, Tateno H, et al. Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema. Biochem Biophys Res Commun 2001; 289: 116-119.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 116-119
    • Minematsu, N.1    Nakamura, H.2    Tateno, H.3
  • 15
    • 8844250037 scopus 로고    scopus 로고
    • Genetic polymorphism in matrix metalloproteinase-9 and the susceptibility to chronic obstructive pulmonary disease in Han population of south China
    • Zhou M, Huang SG, Wan HY, et al. Genetic polymorphism in matrix metalloproteinase-9 and the susceptibility to chronic obstructive pulmonary disease in Han population of south China. Chin Med J (Engl) 2004; 117: 1481-1484.
    • (2004) Chin Med J (Engl) , vol.117 , pp. 1481-1484
    • Zhou, M.1    Huang, S.G.2    Wan, H.Y.3
  • 16
    • 0033031593 scopus 로고    scopus 로고
    • Shortened microsatellite d(CA) 21 sequence down-regulates promoter activity of matrix metalloproteinasee gene
    • Shimajiri S, Arima N, Tanimoto A, et al. Shortened microsatellite d(CA)21 sequence down-regulates promoter activity of matrix metalloproteinasee gene. FEBS Lett 1999; 455: 70-74.
    • (1999) FEBS Lett , vol.455 , pp. 70-74
    • Shimajiri, S.1    Arima, N.2    Tanimoto, A.3
  • 17
    • 0035164768 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-2 gene polymorphisms in chronic obstructive pulmonary disease
    • Hirano K, Sakamoto T, Uchida Y, et al. Tissue inhibitor of metalloproteinases-2 gene polymorphisms in chronic obstructive pulmonary disease. Eur Respir J 2001; 18: 748-752.
    • (2001) Eur Respir J , vol.18 , pp. 748-752
    • Hirano, K.1    Sakamoto, T.2    Uchida, Y.3
  • 18
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt DR. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 2004; 74: 765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 20
    • 69249174673 scopus 로고    scopus 로고
    • MMP-1 polymorphism and its relationship to pathological processes
    • Arakaki PA, Marques MR, Santos MC. MMP-1 polymorphism and its relationship to pathological processes. J Biosci 2009; 34: 313-320.
    • (2009) J Biosci , vol.34 , pp. 313-320
    • Arakaki, P.A.1    Marques, M.R.2    Santos, M.C.3
  • 21
    • 84866554963 scopus 로고    scopus 로고
    • Genes and environment: Novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure
    • Mbewe-Campbell N, Wei Z, Zhang K, et al. Genes and environment: Novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure. J Hypertens 2012; 30: 1961-1969.
    • (2012) J Hypertens , vol.30 , pp. 1961-1969
    • Mbewe-Campbell, N.1    Wei, Z.2    Zhang, K.3
  • 22
    • 80155189685 scopus 로고    scopus 로고
    • Contribution of cystatin C gene polymorphisms to cerebral white matter lesions
    • Mitaki S, Nagai A, Sheikh AM, et al. Contribution of cystatin C gene polymorphisms to cerebral white matter lesions. Cerebrovasc Dis 2011; 32: 489-496.
    • (2011) Cerebrovasc Dis , vol.32 , pp. 489-496
    • Mitaki, S.1    Nagai, A.2    Sheikh, A.M.3
  • 23
    • 12144289605 scopus 로고    scopus 로고
    • Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease
    • Eriksson P, Deguchi H, Samnega°rd A, et al. Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease. Arterioscler Thromb Vasc Biol 2004; 24: 551-557.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 551-557
    • Eriksson, P.1    Deguchi, H.2    Samnegard, A.3
  • 24
    • 0038399757 scopus 로고    scopus 로고
    • Alzheimer disease-associated cystatin C variant undergoes impaired secretion
    • Benussi L, Ghidoni R, Steinhoff T, et al. Alzheimer disease-associated cystatin C variant undergoes impaired secretion. Neurobiol Dis 2003; 13: 15-21.
    • (2003) Neurobiol Dis , vol.13 , pp. 15-21
    • Benussi, L.1    Ghidoni, R.2    Steinhoff, T.3
  • 25
    • 21544476972 scopus 로고    scopus 로고
    • Genotype and plasma concentration of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events
    • LoewM, Hoffmann MM, KoenigW, et al. Genotype and plasma concentration of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events. Arterioscler Thromb Vasc Biol 2005; 25: 1470-1474.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1470-1474
    • Loew, M.1    Hoffmann, M.M.2    Koenig W3
  • 26
    • 74049134939 scopus 로고    scopus 로고
    • MMP12, lung function, and COPD in high-risk populations
    • Hunninghake GM, Cho MH, Tesfaigzi Y, et al. MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009; 361: 2599-2608.
    • (2009) N Engl J Med , vol.361 , pp. 2599-2608
    • Hunninghake, G.M.1    Cho, M.H.2    Tesfaigzi, Y.3
  • 27
    • 0030823772 scopus 로고    scopus 로고
    • Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
    • Hautamaki RD, Kobayashi DK, Senior RM, et al. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997; 277: 2002-2004.
    • (1997) Science , vol.277 , pp. 2002-2004
    • Hautamaki, R.D.1    Kobayashi, D.K.2    Senior, R.M.3
  • 28
    • 0037447184 scopus 로고    scopus 로고
    • Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release
    • Churg A, Wang RD, Tai H, et al. Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am J Respir Crit Care Med 2003; 167: 1083-1089.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1083-1089
    • Churg, A.1    Wang, R.D.2    Tai, H.3
  • 29
    • 0026795140 scopus 로고
    • Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties
    • Okada Y, Gonoji Y, Naka K, et al. Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties. J Biol Chem 1992; 267: 21712-21719.
    • (1992) J Biol Chem , vol.267 , pp. 21712-21719
    • Okada, Y.1    Gonoji, Y.2    Naka, K.3
  • 30
    • 1842416597 scopus 로고    scopus 로고
    • Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase
    • Gronski TJ Jr, Martin RL, Kobayashi DK, et al. Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase. J Biol Chem 1997; 272: 12189-12194.
    • (1997) J Biol Chem , vol.272 , pp. 12189-12194
    • Gronski Jr., T.J.1    Martin, R.L.2    Kobayashi, D.K.3
  • 31
    • 15244355257 scopus 로고    scopus 로고
    • Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease
    • Molet S, Belleguic C, Lena H, et al. Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease. Inflamm Res 2005; 54: 31-36.
    • (2005) Inflamm Res , vol.54 , pp. 31-36
    • Molet, S.1    Belleguic, C.2    Lena, H.3
  • 32
    • 33645068585 scopus 로고    scopus 로고
    • Elevated MMP-12 protein levels in induced sputum from patients with COPD
    • Demedts IK, Morel-Montero A, Lebecque S, et al. Elevated MMP-12 protein levels in induced sputum from patients with COPD. Thorax 2006; 61: 196-201.
    • (2006) Thorax , vol.61 , pp. 196-201
    • Demedts, I.K.1    Morel-Montero, A.2    Lebecque, S.3
  • 33
    • 0036010527 scopus 로고    scopus 로고
    • Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease
    • Russell REK, Culpitt SV, DeMatos C, et al. Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2002; 26: 602-609.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 602-609
    • Russell, R.E.K.1    Culpitt, S.V.2    Dematos, C.3
  • 34
    • 27544503143 scopus 로고    scopus 로고
    • Matrix metalloproteinase-12 and cathepsin D expression in pulmonary macrophages and dendritic cells of cigarette smoke-exposed mice
    • Bracke K, Cataldo D, Maes T, et al. Matrix metalloproteinase-12 and cathepsin D expression in pulmonary macrophages and dendritic cells of cigarette smoke-exposed mice. Int Arch Allergy Immunol 2005; 138: 169-179.
    • (2005) Int Arch Allergy Immunol , vol.138 , pp. 169-179
    • Bracke, K.1    Cataldo, D.2    Maes, T.3
  • 35
    • 0025938633 scopus 로고
    • Cigarette smoking induces an elastolytic cysteine proteinase in macrophages distinct from cathepsin L
    • Reilly JJ Jr, Chen P, Sailor LZ, et al. Cigarette smoking induces an elastolytic cysteine proteinase in macrophages distinct from cathepsin L. Am J Physiol 1991; 261: L41-L48.
    • (1991) Am J Physiol , vol.261
    • Reilly Jr., J.J.1    Chen, P.2    Sailor, L.Z.3
  • 36
    • 0035722954 scopus 로고    scopus 로고
    • Matrix metalloproteinases in lung biology
    • Parks WC, Shapiro SD. Matrix metalloproteinases in lung biology. Respir Res 2001; 2: 10-19.
    • (2001) Respir Res , vol.2 , pp. 10-19
    • Parks, W.C.1    Shapiro, S.D.2
  • 37
    • 0026461115 scopus 로고
    • Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema
    • D'Armiento J, Dalal SS, Okada Y, et al. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell 1992; 71: 955-961.
    • (1992) Cell , vol.71 , pp. 955-961
    • D'Armiento, J.1    Dalal, S.S.2    Okada, Y.3
  • 38
    • 0035077465 scopus 로고    scopus 로고
    • Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema
    • Imai K, Dalal SS, Chen ES, et al. Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema. Am J Respir Crit Care Med 2001; 163: 786-791.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 786-791
    • Imai, K.1    Dalal, S.S.2    Chen, E.S.3
  • 39
    • 0034101866 scopus 로고    scopus 로고
    • Upregulation of gelatinases A and B, collagenasess and 2, and increased parenchymal cell death in COPD
    • Segura-Valdez L, Pardo A, Gaxiola M, et al. Upregulation of gelatinases A and B, collagenasess and 2, and increased parenchymal cell death in COPD. Chest 2000; 117: 684-694.
    • (2000) Chest , vol.117 , pp. 684-694
    • Segura-Valdez, L.1    Pardo, A.2    Gaxiola, M.3
  • 40
    • 77954494717 scopus 로고    scopus 로고
    • Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease
    • Gosselink JV, Hayashi S, Elliott WM, et al. Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010; 181: 1329-1335.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 1329-1335
    • Gosselink, J.V.1    Hayashi, S.2    Elliott, W.M.3
  • 41
    • 84863898701 scopus 로고    scopus 로고
    • Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice
    • Xu B, Chen H, Xu W, et al. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol 2012; 303: L89-L96.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.303
    • Xu, B.1    Chen, H.2    Xu, W.3
  • 42
    • 48949119331 scopus 로고    scopus 로고
    • Transgenic expression of matrix metalloproteinase-9 causes adult-onset emphysema in mice associated with the loss of alveolar elastin
    • Foronjy R, Nkyimbeng T, Wallace A, et al. Transgenic expression of matrix metalloproteinase-9 causes adult-onset emphysema in mice associated with the loss of alveolar elastin. Am J Physiol Lung Cell Mol Physiol 2008; 294: L1149-L1157.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Foronjy, R.1    Nkyimbeng, T.2    Wallace, A.3
  • 43
    • 4444322565 scopus 로고    scopus 로고
    • Tumor necrosis factor-A drives 70% of cigarette smoke-induced emphysema in the mouse
    • Churg A, Wang RD, Tai H, et al. Tumor necrosis factor-A drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med 2004; 170: 492-498.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 492-498
    • Churg, A.1    Wang, R.D.2    Tai, H.3
  • 44
    • 0036853166 scopus 로고    scopus 로고
    • Thymocyte expression of cathepsin L is essential for NKT cell development
    • Honey K, Benlagha K, Beers C, et al. Thymocyte expression of cathepsin L is essential for NKT cell development. Nat Immunol 2002; 3: 1069-1074.
    • (2002) Nat Immunol , vol.3 , pp. 1069-1074
    • Honey, K.1    Benlagha, K.2    Beers, C.3
  • 45
    • 42449151214 scopus 로고    scopus 로고
    • Functions of natural killer cells
    • Vivier E, Tomasello E, Baratin M, et al. Functions of natural killer cells. Nat Immunol 2008; 9: 503-510.
    • (2008) Nat Immunol , vol.9 , pp. 503-510
    • Vivier, E.1    Tomasello, E.2    Baratin, M.3
  • 46
    • 0034948629 scopus 로고    scopus 로고
    • Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferó n)
    • Prieto A, Reyes E, Bernstein ED, et al. Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferó n). Am J Respir Crit Care Med 2001; 163: 1578-1583.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 1578-1583
    • Prieto, A.1    Reyes, E.2    Bernstein, E.D.3
  • 47
    • 0032540474 scopus 로고    scopus 로고
    • Cathepsin L: Critical role in Ii degradation and CD4 T cell selection in the thymus
    • Nakagawa T, Roth W, Wong P, et al. Cathepsin L: Critical role in Ii degradation and CD4 T cell selection in the thymus. Science 1998; 280: 450-453.
    • (1998) Science , vol.280 , pp. 450-453
    • Nakagawa, T.1    Roth, W.2    Wong, P.3
  • 48
    • 0034864828 scopus 로고    scopus 로고
    • Treatment with cathepsin L inhibitor potentiates Th2-type immune response in Leishmania major-infected BALB/c mice
    • Zhang T, Maekawa Y, Sakai T, et al. Treatment with cathepsin L inhibitor potentiates Th2-type immune response in Leishmania major-infected BALB/c mice. Int Immunol 2001; 13: 975-982.
    • (2001) Int Immunol , vol.13 , pp. 975-982
    • Zhang, T.1    Maekawa, Y.2    Sakai, T.3
  • 49
    • 78149359763 scopus 로고    scopus 로고
    • Expression of human cathepsin L or human cathepsin v in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice
    • Sevenich L, Hagemann S, Stoeckle C, et al. Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice. Biochimie 2010; 92: 1674-1680.
    • (2010) Biochimie , vol.92 , pp. 1674-1680
    • Sevenich, L.1    Hagemann, S.2    Stoeckle, C.3
  • 50
    • 84865136781 scopus 로고    scopus 로고
    • Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment
    • Schurigt U, Eilenstein R, Gajda M, et al. Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment. Inflamm Res 2012; 61: 1021-1029.
    • (2012) Inflamm Res , vol.61 , pp. 1021-1029
    • Schurigt, U.1    Eilenstein, R.2    Gajda, M.3
  • 51
    • 78349308399 scopus 로고    scopus 로고
    • Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides
    • Funkelstein L, Beinfeld M, Minokadeh A, et al. Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides. Neuropeptides 2010; 44: 457-466.
    • (2010) Neuropeptides , vol.44 , pp. 457-466
    • Funkelstein, L.1    Beinfeld, M.2    Minokadeh, A.3
  • 52
    • 79952278134 scopus 로고    scopus 로고
    • Neuropeptide expression in the airways of COPD patients and smokers with normal lung function
    • Vatrella A, Montagnani S, Calabrese C, et al. Neuropeptide expression in the airways of COPD patients and smokers with normal lung function. J Biol Regul Homeost Agents 2010; 24: 425-432.
    • (2010) J Biol Regul Homeost Agents , vol.24 , pp. 425-432
    • Vatrella, A.1    Montagnani, S.2    Calabrese, C.3
  • 53
    • 80055005681 scopus 로고    scopus 로고
    • Impaired adrenergic- and corticotropic-axis outflow during exercise in chronic obstructive pulmonary disease
    • Iranmanesh A, Rochester DF, Liu J, et al. Impaired adrenergic- and corticotropic-axis outflow during exercise in chronic obstructive pulmonary disease. Metabolism 2011; 60: 1521-1529.
    • (2011) Metabolism , vol.60 , pp. 1521-1529
    • Iranmanesh, A.1    Rochester, D.F.2    Liu, J.3
  • 54
    • 0034959118 scopus 로고    scopus 로고
    • Cell culture conditions affect LPS inducibility of the inflammatory mediators in J774A.1 murine macrophages
    • Cohly H, Stephens J, Markhov A, et al. Cell culture conditions affect LPS inducibility of the inflammatory mediators in J774A.1 murine macrophages. Immunol Invest 2001; 30: 1-15.
    • (2001) Immunol Invest , vol.30 , pp. 1-15
    • Cohly, H.1    Stephens, J.2    Markhov, A.3
  • 55
    • 27344455035 scopus 로고    scopus 로고
    • The expression of native and cultured human retinal pigment epithelial cells grown in different culture conditions
    • Tian J, Ishibashi K, Honda S, et al. The expression of native and cultured human retinal pigment epithelial cells grown in different culture conditions. Br J Ophthalmol 2005; 89: 1510-1517.
    • (2005) Br J Ophthalmol , vol.89 , pp. 1510-1517
    • Tian, J.1    Ishibashi, K.2    Honda, S.3
  • 56
    • 77951997255 scopus 로고    scopus 로고
    • Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
    • Neumann E, Riepl B, Knedla A, et al. Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts. Arthritis Res Ther 2010; 12: R83.
    • (2010) Arthritis Res Ther , vol.12
    • Neumann, E.1    Riepl, B.2    Knedla, A.3
  • 57
    • 84870353204 scopus 로고    scopus 로고
    • Gene expression profiles in alveolar macrophages induced by lipopolysaccharide in humans
    • Reynier F, de Vos AF, Hoogerwerf JJ, et al. Gene expression profiles in alveolar macrophages induced by lipopolysaccharide in humans. Mol Med 2012; 18: 1303-1311.
    • (2012) Mol Med , vol.18 , pp. 1303-1311
    • Reynier, F.1    De Vos, A.F.2    Hoogerwerf, J.J.3
  • 58
    • 84873523398 scopus 로고    scopus 로고
    • Current evidence on the relationship between five polymorphisms in the matrix metalloproteinases (MMP) gene and lung cancer risk: A meta-analysis
    • Hu C, Wang J, Xu Y, et al. Current evidence on the relationship between five polymorphisms in the matrix metalloproteinases (MMP) gene and lung cancer risk: A meta-analysis. Gene 2013; 517: 65-71.
    • (2013) Gene , vol.517 , pp. 65-71
    • Hu, C.1    Wang, J.2    Xu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.