Chronic obstructive pulmonary disease • 2: Pathology and biochemistry of emphysema

Thorax

Volumn 57, Issue 9, 2002, Pages 830-834

  Hogg, J C ^a   Senior, R M ^b  

^a ST PAUL S HOSPITAL   (Canada)

^b BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; GELATINASE B; LEUKOCYTE ELASTASE; LUNG ENZYME; MATRIX METALLOPROTEINASE;

BIOCHEMISTRY; CELL KINETICS; CHRONIC OBSTRUCTIVE LUNG DISEASE; DEGRADATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; LEUKOCYTE MOTILITY; LUNG ALVEOLUS WALL; LUNG EMPHYSEMA; LUNG INJURY; NONHUMAN; PATHOGENESIS; PATHOLOGY; PRIORITY JOURNAL; REVIEW;

ENDOPEPTIDASES; HUMANS; LEUKOCYTES; METALLOENDOPEPTIDASES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA;

EID: 0036729605     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.57.9.830     Document Type: Review

References (52)

1. Types of injury: Destruction of the respiratory tract
2. Terminology, definitions and classifications of chronic pulmonary emphysema and related conditions
3. Definition of emphysema. Report of a National Heart, Lung and Blood Institute, Division of Lung Diseases
4. Microscopic anatomy of pulmonary emphysema
5. Centrilobular form of hypertrophic emphysema and its relation to chronic bronchitis
6. Further observations on the pathology of pulmonary emphysema in chronic bronchitis
7. The incidence of pulmonary emphysema with observations on the relative incidence and spatial distribution of various types of emphysema
8. Chronic pulmonary emphysema: Anatomy and pathogenesis
9. Emphysema
10. Panlobular emphysema: Anatomy and pathogenesis
11. Neutrophil kinetics and lung injury
12. The effect of cigarette smoking on neutrophil kinetics in human lungs
13. Quantification of neutrophil migration in acute bacterial pneumonia in rabbits
14. Fibroblasts are in a position to provide directional information to migrating neutrophils during pneumonia in rabbit lungs
15. Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B
16. The pathogenesis of emphysema: The elastase:antielastase hypothesis 30 years later
17. Animal models of chronic obstructive pulmonary disease
18. Effects of cigarette smoke in mice with different levels of α1-proteinase inhibitor and sensitivity to oxidants
19. Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema
20. Alveolar inflammation and its relation to emphysema in smokers
21. Amplification of inflammation in emphysema and its association with latent adenoviral infection
22. Relationship of alveolar macrophage plasminogen activator and elastase activities to lung function and CT evidence of emphysema
23. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes
24. Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema
25. Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase
26. Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias
27. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
28. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
29. Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
30. Induction of emphysematous lesions in rat lung by beta-D-xyloside, an inhibitor of proteoglycan synthesis
31. Acute effect of smoking on elastaselike esterase activity and immunologic neutrophil elastase levels in bronchoalveolar lavage fluid
32. Neutrophil granule protein in bronchoalveolar lavage fluid from subjects with subclinical emphysema
33. 1 in community-based older volunteers with higher levels of neutrophil elastase in bronchoalveolar lavage fluid
34. Proteinase-antiproteinase imbalance in the pathogenesis of emphysema: The role of metalloproteinases in lung damage
35. Matrix metalloproteinases in lung biology
36. Matrix metalloproteinases. Matrix degradation and more
37. Requirement for macrophage elastase for cigarette induced emphysema in mice
38. Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema
39. Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema
40. Relationship between elastolytic activity and experimental emphysema-induced properties of papain preparations
41. Morphogenesis of abnormal elastic fibers in lungs of patients with panacinar and centriacinar emphysema
42. The role of collagenase in emphysema
43. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema
44. Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha-1-antitrypsin
45. Smoke-induced emphysema in guinea pigs is associated with morphometric evidence of collagen breakdown and repair
46. Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs
47. Cellular and connective tissue changes in alveolar septal walls in emphysema
48. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema
49. Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients
50. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD