The macrophage in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 5 II, 1999, Pages

  Shapiro, Steven D ^a,b  

^a ST LOUIS CHILDREN S HOSPITAL   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; EMPHYSEMA; HOST RESISTANCE; HUMAN; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0032698544     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.supplement_1.9     Document Type: Conference Paper

References (22)

1. Bartecchi, C., T. MacKenzie, and K. Schrier. 1994. The human costs of tobacco use. N. Engl. J. Med. 330:907-912, 975-980.
2. Senior, R. M., and S. D. Shapiro. 1997. Chronic obstructive pulmonary disease: epidemiology, pathophysiology and pathogenesis. In Fishman's Pulmonary Diseases and Disorders, 3rd ed. McGraw-Hill, New York.
3. Liou, T. G., and E. J. Campbell. 1996. Quantum proteolysis resulting from release of single granules by human neutrophils: a novel, nonoxidative mechanism of extracellular proteolytic activity. J. Immunol. 157: 2624-2631.
4. Belaaouaj, A., R. McCarthy, M. Baumann, Z. Gao, T. J. Ley, S. N. Abraham, and S. D. Shapiro. 1998. Impaired host defense against bacterial infection in mice lacking neutrophil elastase. Nature Med.
5. Busiek, D. F., F. P. Ross, S. McDonnell, G. Murphy, L. M. Matrisian, and H. G. Welgus. 1992. The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes. J. Biol. Chent. 13:9087-9092.
6. Owen, C. A., M. A. Campbell, S. S. Boukedes, R. A. Stockley, E. J. Campbell. 1994. A discrete subpopulation of human monocytes expresses a neutrophil-like proinflaminatory (P) phenotype. Am. J. Physiol. 267:775-785.
7. Campbell, E. J., J. D. Cury, S. D. Shapiro, G. I. Goldberg, and H. G. Welgus. 1991. Neutral proteinases of human mononuclear phagocytes - cellular-differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases. J. Immunol. 146:1286-1293.
8. Banda, M. J., and Z. Werb. 1981. Mouse macrophage elastase. Purification and characterization as a metalloproteinase. Biochem. J. 193: 589-605.
9. Shapiro, S. D., G. Griffin, D. J. Gilbert, N. A. Jenkins, N. G. Copeland, H. G. Welgus, K. M. Senior, and T. J. Ley. 1992. Molecular cloning, chromosomal localization and bacterial expression of a novel murine macrophage metalloelastase. J. Biol. Chem. 267:4664-4671.
10. Shapiro, S. D., D. Kobayashi, and T. Ley. 1993. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J. Biol. Chem. 268:23824-23829.
11. Cornelius, L. A., L. Nehring, B. Klein, R. Pierce, M. Bolinski, H. G. Welgus, and S. D. Shapiro. 1998. Generation of angiostatin by matrix metalloproteinases: effects on neovascularization. J. Immunol (In press)
12. Chandler, S., J. Cossins, J. Lury, and G. Wells. 1996. Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-alpha fusion protein. Biochem. Biophys. Res. Commun. 228:421-429.
13. Shipley, J. M., R. L. Wesselschmidt, D. K. Kobayashi, T. J. Ley, and S. D. Shapiro. 1996. Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc. Natl. Acad. Sci. U.S.A. 93:3942-3946.
14. Finlay, G. A., L. R. O'Dristoll, K. J. Russell, E. M. D'Arcy, J. B. Masterson, M. X. Fitzgerald, and C. M. O'Connor. 1997. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am. J. Respir. Crit. Care Med. 156:240-247.
15. D'Armiento, J., S. S. Dalal, Y. Okada, R. A. Berg, and K. Chada. 1992. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell 71:955-961.
16. Nagai, A., H. Inano, K. Matsuba, and W. M. Thurlbeck. 1994. Scanning electronmicroscopic morphometry of emphysema in humans. Am. J. Respir. Crit. Care Med. 150:1411-1415.
17. Wright, J. L. 1995. Emphysema: Concepts under change - a pathologists perspective. Modern Pathol. 8:873-880.
18. Wright, J. L., and A. Churg. 1995. Smoke-induced emphysema in guinea pigs is associated with morphometric evidence of collagen breakdown and repair. Am. J. Physiol. 268:L17-L20.
19. Hautamaki, R. D., D. K. Kobayashi, R. M. Senior, and S. D. Shapiro. 1997. Macrophage elastase is required for cigarette smoke-induced emphysema in mice. Science 277:2002-2004.
20. Shapiro, S. B. 1995. The pathogenesis of emphysema: the elastase:anti-elastase hypothesis 30 years later. Proc. Am. Assoc. Phys. 107(3):346-352.
21. Senior, R. M., G. L. Griffin, and R. P. Mecham. 1980. Chemotactic activity of elastin-derived peptides, J. Clin. Invest. 66:859-862.
22. Hunninghake, G. W., J. M. Davidson, S. Rennard, S. Szapiel, J. E. Gadek, and R. G. Crystal. 1981. Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science 212: 925-927.