A mitochondria-targeted mass spectrometry probe to detect glyoxals: Implications for diabetes

Free Radical Biology and Medicine

Volumn 67, Issue , 2014, Pages 437-450

  Pun, Pamela Boon Li ^a   Logan, Angela ^a   Darley Usmar, Victor ^b   Chacko, Balu ^b   Johnson, Michelle S ^b   Huang, Guang W ^b   Rogatti, Sebastian ^a   Prime, Tracy A ^a   Methner, Carmen ^c   Krieg, Thomas ^c   Fearnley, Ian M ^a   Larsen, Lesley ^d   Larsen, David S ^d   Menger, Katja E ^a   Collins, Yvonne ^a   James, Andrew M ^a   Kumar, G D Kishore ^e   Hartley, Richard C ^e   Smith, Robin A J ^d   Murphy, Michael P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF OTAGO   (New Zealand)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Exomarker; Free radicals; Glyoxal; Hyperglycemia; Methylglyoxal; Mitochondria; MitoG

Indexed keywords

1,2 DICARBONYL DERIVATIVE; 1,2 PHENYLENEDIAMINE; GLYOXAL; METHYLGLYOXAL; MITOCHONDRIA TARGETED REAGENT; MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG; MOLECULAR PROBE; ORGANOPHOSPHORUS COMPOUND; PHENYLENEDIAMINE DERIVATIVE; REAGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIABETES MELLITUS; HYPERGLYCEMIA; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; ANIMAL; BOVINE; CELL LINE; CHEMISTRY; DIABETES MELLITUS, TYPE 1; DISEASE MODEL; ENDOTHELIUM CELL; LIQUID CHROMATOGRAPHY; LIVER MITOCHONDRION; METABOLISM; MOLECULAR PROBE; MYOBLAST; OXIDATIVE STRESS; PATHOLOGY; RAT; SYNTHESIS; GLYCATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; QUANTITATIVE ANALYSIS;

ANIMALS; CATTLE; CELL LINE; CHROMATOGRAPHY, LIQUID; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GLYOXAL; HYPERGLYCEMIA; MICE; MITOCHONDRIA, LIVER; MOLECULAR PROBES; MYOBLASTS; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; PHENYLENEDIAMINES; PYRUVALDEHYDE; RATS; TANDEM MASS SPECTROMETRY;

EID: 84891805718     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.11.025     Document Type: Article

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