Analysis of methylglyoxal metabolism in CHO cells grown in culture

Cytotechnology

Volumn 48, Issue 1-3, 2005, Pages 1-13

  Kingkeohoi, Sarocha ^a   Chaplen, Frank W R ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

CHO cell; Inhibitor; Metabolism; Metabolite; Methylglyoxal

Indexed keywords

CARBON; GLYOXALASE; LACTIC ACID; METHYLGLYOXAL; NUCLEIC ACID; PHOSPHATE; PROTEIN;

ANIMAL CELL; ARTICLE; BATCH CELL CULTURE; CELL CULTURE; CELL DEATH; CELL FUNCTION; CELL GROWTH; CELL METABOLISM; CELLULAR DISTRIBUTION; CHO CELL; ENZYME ACTIVITY; FEMALE; GLYCOLYSIS; KINETICS; MAMMAL; MEASUREMENT; NONHUMAN; PROTEIN MODIFICATION; QUALITATIVE ANALYSIS; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

ANIMALIA; MAMMALIA;

EID: 28744442711     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-005-1920-6     Document Type: Article

References (35)

1. M.U. Ahmed E. Brinkmann Frye T.P. Degenhardt S.R. Thorpe J.W. Baynes 1997 N-ε-(carboxyethyl)lysinea product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins Biochem. J. 324 565 70
2. G. Alberts D. Bray J. Lewis M. Raff K. Roberts J.D. Watson 1994 Molecular Biology of the Cell 3 Garland Publishing Inc. New York
3. D.C. Anderson C.F. Goochee 1995 The effect of ammonia on O-linked glycosylation of granulocyte colony-stimulating factor produced by Chinese hamster ovary cells Biotechnol. Bioeng. 47 96 105
4. T.A. Bibila D.K. Robinson 1995 In pursuit of the optimal fed-batch process for monoclonal antibody production Biotechnol. Prog. 11 1 13
5. M. Bourajjaj C.D.A. Stehouwer V.W.M. van Hinsbergh C.G. Schalkwijk 2003 Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus Biochem. Soc. Trans. 31 6 1400 1402
6. F.W.R. Chaplen D.C. Cameron W.E. Fahl 1996a Effect of endogenous methylglyoxal on Chinese hamster ovary cells grown in culture Cytotechnology 22 33 42
7. F.W.R. Chaplen W.E. Fahl D.C. Cameron 1996b Method for determination of free extracellular and intracellular methylglyoxal in animal cells grown in culture Anal. Biochem. 238 171 178
8. F.W.R. Chaplen W.E. Fahl D.C. Cameron 1998 Evidence of high levels of methylglyoxal in Chinese hamster ovary cells grown in culture Proc. Natl. Acad. Sci. USA 95 5533 5538
9. D.J. Creighton M. Migliorine T. Pourmotabbed M.K. Guha 1988 Optimization of the efficiency of the glyoxalase pathway Biochemistry 27 19 7376 84
10. J. Du H. Suzuki F. Nagase A.A. Akhand T. Yokoyama T. Miyata K. Kurokawa I. Nakashima 2000 Methylglyoxal induces apoptosis in Jurkat leukemia cells by activating c-Jun N-terminal kinase J. Cell. Biochem. 77 2 333 44
11. J.P. Godbout J. Pesavento M.E. Hartman S.R. Manson G.G. Freund 2001 Methyglyoxal enhances cisplatin-induced cytotoxicity by activating PKC-δ J. Biol. Chem. 277 4 2554 2561
12. P.C. Jocelyn 1977 Biochemistry of the SH Group Academic Press New York
13. T.W.C. Lo M.E. Westwood A.C. [tmp] McLellan T. Selwood P.J. Thornalley 1994 Binding and modification of proteins by methylglyoxal under physiological conditions J. Biol. Chem. 269 32299 32305
14. Z. Makita H. Vlassara A. Cerami R. Bucala 1992 Immunochemical detection of advanced glycosylation end products in vivo J. Biol. Chem. 267 8 5133 5138
15. A.M. Martins P. Mendes C. Cordeiro A.P. Freire 2001 In situ kinetic analysis of glyoxalase I and glyoxalase II in Saccharomyces cerevisiae Eur. J. Biochem. 268 14 3930 3936
16. A.C. [tmp] McLellan S.A. Phillips P.J. Thornalley 1992 Fluorimetric assay of D-lactate Anal. Biochem. 206 1 12 6
17. W.M. Miller H.W. Blanch 1991 Regulation of animal cell metabolism in bioreactors C.S Ho D.I.C. Wang Animal Cell Bioreactors, Ch. 6 Butterworth-Heinemann Boston 119 157
18. A. Papsoulis Y. Al-Abed R. Bucala 1995 Identification of N2-(1-carboxyethyl)guanine (CEG) as a guanine advanced glycosylation end-product Biochemistry 34 648 655
19. J.P. Richard 1991 Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance Biochemistry 30 4581 4585
20. H. Sakamoto T. Mashima A. Kizaki S. Dan Y. Hashimote M. Naito T. Tsuruo 2000 Glyoxalase I is involved in the resistance of human leukemia cells to antitumor agent-induced apoptosis Blood 95 10 3214 3218
21. F.A. Shamsi A. Partal C. Sady M.A. Glomb R.H. Nagaraj 1998 Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes J. Biol. Chem. 273 12 6928 6936
22. M. Shinohara P.J. Thornalley I. Giadino 1998 Overexpression of glyoxalase I in bovine endothelial cells inhibits intracellular advanced glycation end-product formation and prevents hyperglycemia-induced increases in macromolecular endocytosis J. Clin. Invest. 101 5 1142 1147
23. K. Takahashi 1968 The reaction of phenylglyoxal with arginine residues in proteins J. Biochem. (Tokyo) 23 6171 6179
24. P.J. Thornalley 1988 Modification of the glyoxalase system in human red blood cells by glucose in vitro Biochem. J. 254 751 755
25. P.J. Thornalley 1990 The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life Biochem. J. 269 1 11
26. P.J. Thornalley 1996 Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification - a role in pathogenesis and antiproliferative chemotherapy Gen. Pharmacol. 27 4 565 573
27. P.J. Thornalley L.G. Edwards Y. Kang C. Wyatt N. Davies M.J. Ladan J. Double 1996 Antitumor activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro in vivo. Inhibition of glyoxalase I and the induction of apoptosis Biochem. Pharmacol. 51 10 1365 1372
28. 32P-postlabelling method for the analysis of 2'-deoxyguanosine-3'- monophosphate and DNA adducts of methylglyoxal Carcinogenesis 15 1887 1894
29. D.L. Vander Jagt R.K. Hassebrook L.A. Hunsaker W.M. Brown R.E. Royer 2001 Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications Chem. Biol. Interact. 130-132 13 549 562
30. D.L. Vander Jagt L.P. Han C.H. Lehman 1972 Kinetic evaluation of substrate specificity in the glyoxalase I disproportionation of α-ketoaldehydes Biochemistry 11 20 3735 3740
31. F. Van Herreweghe J. Mao F.W.R. Chaplen J. Grooten K. Gevaert J. Vandekerckhove K. Vancompernolle 2002 Tumor Necrosis Factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of specific methylglyoxal-derived AGEs Proc. Natl. Acad. Sci. USA 99 2 949 954
32. K. Uchida O.T. Khor O. Oya T. Osawa Y. Yasuda T. Miyata 1997 Protein modification by Maillard reaction intermediate methylglyoxal. Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo FEBS Lett. 410 2-3 313 318
33. M.E. Westwood A.C. [tmp] McLellan P.J. Thornalley 1994 Receptor-mediated endocytic uptake of methylglyoxal-modified serum albumin J. Biol. Chem. 269 32293 32298
34. M.E. Westwood P.J. Thornalley 1996 Induction of synthesis and secretion of interleukin 1β in the human monocyteic THP-1 cells by human serum albumins modified by methylglyoxal and advanced glycation endproducts Immunol. Lett. 50 17 21
35. L. Xie D.I. Wang 1994 Applications of an improved stoichiometric model in medium design and fed-batch cultivation of animal cells in a bioreactor Cytotechnology 15 1-3 17 29