-
1
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
Xie ZP, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-1109.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.P.1
Klionsky, D.J.2
-
3
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
4
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J Cell Biol 1992; 119:301-311.
-
(1992)
J Cell Biol
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
5
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 1993; 333:169-174.
-
(1993)
FEBS Lett
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
6
-
-
0028800171
-
Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway
-
Harding TM, Morano KA, Scott SV, Klionsky DJ. Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol 1995; 131:591-602.
-
(1995)
J Cell Biol
, vol.131
, pp. 591-602
-
-
Harding, T.M.1
Morano, K.A.2
Scott, S.V.3
Klionsky, D.J.4
-
7
-
-
0033791650
-
Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells
-
Kim J, Klionsky DJ. Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annu Rev Biochem 2000; 69:303-342.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 303-342
-
-
Kim, J.1
Klionsky, D.J.2
-
8
-
-
77957198526
-
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
-
Mari M, Griffith J, Rieter E, Krishnappa L, Klionsky DJ, Reggiori F. An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. J Cell Biol 2010; 190:1005-1022.
-
(2010)
J Cell Biol
, vol.190
, pp. 1005-1022
-
-
Mari, M.1
Griffith, J.2
Rieter, E.3
Krishnappa, L.4
Klionsky, D.J.5
Reggiori, F.6
-
9
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto H, Kakuta S, Watanabe TM, et al. Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol 2012; 198:219-233.
-
(2012)
J Cell Biol
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
Kakuta, S.2
Watanabe, T.M.3
-
10
-
-
0346503885
-
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
-
Reggiori F, Tucker KA, Stromhaug PE, Klionsky DJ. The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 2004; 6:79-90.
-
(2004)
Dev Cell
, vol.6
, pp. 79-90
-
-
Reggiori, F.1
Tucker, K.A.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
11
-
-
84878421591
-
Aggrephagy: Lessons from Celegans
-
Lu Q, Wu F, Zhang H. Aggrephagy: lessons from Celegans. Biochem J 2013; 452:381-390.
-
(2013)
Biochem J
, vol.452
, pp. 381-390
-
-
Lu, Q.1
Wu, F.2
Zhang, H.3
-
12
-
-
58249085224
-
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in Celegans
-
Zhang YX, Yan LB, Zhou Z, et al. SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in Celegans. Cell 2009; 136:308-321.
-
(2009)
Cell
, vol.136
, pp. 308-321
-
-
Zhang, Y.X.1
Yan, L.B.2
Zhou, Z.3
-
13
-
-
77950483610
-
Role of autophagy in Caenorhabditis elegans
-
Kovcs AL, Zhang H. Role of autophagy in Caenorhabditis elegans. FEBS Lett 2010; 584:1335-1341.
-
(2010)
FEBS Lett
, vol.584
, pp. 1335-1341
-
-
Kovcs, A.L.1
Zhang, H.2
-
14
-
-
77953713630
-
Celegans screen identifies autophagy genes specific to multicellular organisms
-
Tian Y, Li ZP, Hu WQ, et al. Celegans screen identifies autophagy genes specific to multicellular organisms. Cell 2010; 141:1042-1055.
-
(2010)
Cell
, vol.141
, pp. 1042-1055
-
-
Tian, Y.1
Li, Z.P.2
Hu, W.Q.3
-
15
-
-
80051474094
-
The WD40 repeat PtdIns( 3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes
-
Lu Q, Yang PG, Huang XX, et al. The WD40 repeat PtdIns( 3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. Dev Cell 2011; 21:343-357.
-
(2011)
Dev Cell
, vol.21
, pp. 343-357
-
-
Lu, Q.1
Yang, P.G.2
Huang, X.X.3
-
16
-
-
67650249774
-
Epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in Celegans
-
Tian E, Wang FX, Han JH, Zhang H. epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in Celegans. Autophagy 2009; 5:608-615.
-
(2009)
Autophagy
, vol.5
, pp. 608-615
-
-
Tian, E.1
Wang, F.X.2
Han, J.H.3
Zhang, H.4
-
17
-
-
79551539513
-
The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway in Celegans
-
Yang PG, Zhang H. The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway in Celegans. Autophagy 2011; 7:159-165.
-
(2011)
Autophagy
, vol.7
, pp. 159-165
-
-
Yang, P.G.1
Zhang, H.2
-
18
-
-
84867251783
-
The Celegans ATG101 homolog EPG-9 directly interacts with EPG- 1/Atg13 and is essential for autophagy
-
Liang QQ, Yang PG, Tian E, Han JH, Zhang H. The Celegans ATG101 homolog EPG-9 directly interacts with EPG- 1/Atg13 and is essential for autophagy. Autophagy 2012; 8:1426-1433.
-
(2012)
Autophagy
, vol.8
, pp. 1426-1433
-
-
Liang, Q.Q.1
Yang, P.G.2
Tian, E.3
Han, J.H.4
Zhang, H.5
-
19
-
-
84876308090
-
Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration
-
Zhao HY, Zhao YG, Wang XW, et al. Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration. J Cell Biol 2013; 200:731-741.
-
(2013)
J Cell Biol
, vol.200
, pp. 731-741
-
-
Zhao, H.Y.1
Zhao, Y.G.2
Wang, X.W.3
-
20
-
-
84865518164
-
Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans
-
Wu F, Li YP, Wang F, Noda NN, Zhang H. Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans. J Biol Chem 2012; 287:29457-29467.
-
(2012)
J Biol Chem
, vol.287
, pp. 29457-29467
-
-
Wu, F.1
Li, Y.P.2
Wang, F.3
Noda, N.N.4
Zhang, H.5
-
21
-
-
84890849916
-
The two Celegans Atg16 homologs have partially redundant functions in the basal autophagy pathway
-
In press
-
Zhang H, Wu F, Wang XW, Du HW, Wang XC, Zhang H. The two Celegans Atg16 homologs have partially redundant functions in the basal autophagy pathway. Autophagy 2013; 9: (in press).
-
(2013)
Autophagy
, vol.9
-
-
Zhang, H.1
Wu, F.2
Wang, X.W.3
Du, H.W.4
Wang, X.C.5
Zhang, H.6
-
22
-
-
38549176248
-
Specification of the germ line
-
Jul
-
Strome S. Specification of the germ line. WormBook 2005 Jul 28:1-10.
-
(2005)
WormBook
, vol.28
, pp. 1-10
-
-
Strome, S.1
-
23
-
-
84876339267
-
The scaffold protein EPG-7 links cargo-receptor complexes with the autophagic assembly machinery
-
Lin L, Yang PG, Huang XX, Zhang H, Lu Q, Zhang H. The scaffold protein EPG-7 links cargo-receptor complexes with the autophagic assembly machinery. J Cell Biol 2013; 201:113-129.
-
(2013)
J Cell Biol
, vol.201
, pp. 113-129
-
-
Lin, L.1
Yang, P.G.2
Huang, X.X.3
Zhang, H.4
Lu, Q.5
Zhang, H.6
-
24
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen T, Lamark T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 2011; 7:279-296.
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
25
-
-
84887132374
-
Arginine methylation modulates autophagic degradation of PGL granules in
-
Li SH, Yang PG, Tian E, Zhang H. Arginine methylation modulates autophagic degradation of PGL granules in Celegans. Mol Cell 2013; 52:421-433.
-
(2013)
C. Elegans. Mol Cell
, vol.52
, pp. 421-433
-
-
Li, S.H.1
Yang, P.G.2
Tian, E.3
Zhang, H.4
-
26
-
-
0036901104
-
Mechanism of cargo selection in the cytoplasm-to-vacuole targeting pathway
-
Shintani T, Huang WP, Stromhaug PE, Klionsky DJ. Mechanism of cargo selection in the cytoplasm-to-vacuole targeting pathway. Dev Cell 2002; 3:825-837.
-
(2002)
Dev Cell
, vol.3
, pp. 825-837
-
-
Shintani, T.1
Huang, W.P.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
27
-
-
29644435706
-
Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast
-
Nair U, Klionsky DJ. Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast. J Biol Chem 2005; 280:41785-41788.
-
(2005)
J Biol Chem
, vol.280
, pp. 41785-41788
-
-
Nair, U.1
Klionsky, D.J.2
-
28
-
-
33845692364
-
Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast
-
He C, Song H, Yorimitsu T, et al. Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast. J Cell Biol 2006; 175:925-935.
-
(2006)
J Cell Biol
, vol.175
, pp. 925-935
-
-
He, C.1
Song, H.2
Yorimitsu, T.3
-
29
-
-
16344365254
-
Atg11 links cargo to the vesicleforming machinery in the cytoplasm to vacuole targeting pathway
-
Yorimitsu T, Klionsky DJ. Atg11 links cargo to the vesicleforming machinery in the cytoplasm to vacuole targeting pathway. Mol Biol Cell 2005; 16:1593-1605.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 1593-1605
-
-
Yorimitsu, T.1
Klionsky, D.J.2
-
30
-
-
33846514235
-
Hierarchy of Atg proteins in pre-autophagosomal structure organization
-
Suzuki K, Kubota Y, Sekito T, Ohsumi Y. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 2007; 12:209-218.
-
(2007)
Genes Cells
, vol.12
, pp. 209-218
-
-
Suzuki, K.1
Kubota, Y.2
Sekito, T.3
Ohsumi, Y.4
-
32
-
-
67650246357
-
Mitochondriaanchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
Okamoto K, Kondo-Okamoto N, Ohsumi Y. Mitochondriaanchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 2009; 17:87-97.
-
(2009)
Dev Cell
, vol.17
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
33
-
-
67650264633
-
Atg32 is a mitochondrial protein that confers selectivity during mitophagy
-
Kanki T, Wang K, Cao Y, Baba M, Klionsky DJ. Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 2009; 17:98-109.
-
(2009)
Dev Cell
, vol.17
, pp. 98-109
-
-
Kanki, T.1
Wang, K.2
Cao, Y.3
Baba, M.4
Klionsky, D.J.5
-
34
-
-
77950903972
-
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
-
Filimonenko M, Isakson P, Finley KD, et al. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy. Mol Cell 2010; 38:265-279.
-
(2010)
Mol Cell
, vol.38
, pp. 265-279
-
-
Filimonenko, M.1
Isakson, P.2
Finley, K.D.3
-
35
-
-
43149090064
-
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
-
Hara T, Takamura A, Kishi C, et al. FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 2008; 181:497-510.
-
(2008)
J Cell Biol
, vol.181
, pp. 497-510
-
-
Hara, T.1
Takamura, A.2
Kishi, C.3
-
36
-
-
63049132756
-
Acetylation targets mutant huntingtin to autophagosomes for degradation
-
Jeong H, Then F, Melia TJ, et al. Acetylation targets mutant huntingtin to autophagosomes for degradation. Cell 2009; 137:60-72.
-
(2009)
Cell
, vol.137
, pp. 60-72
-
-
Jeong, H.1
Then, F.2
Melia, T.J.3
-
37
-
-
82455172117
-
Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins
-
Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Mol Cell 2011, 44:279-289.
-
(2011)
Mol Cell
, vol.44
, pp. 279-289
-
-
Matsumoto, G.1
Wada, K.2
Okuno, M.3
Kurosawa, M.4
Nukina, N.5
-
38
-
-
80052197610
-
Phosphorylation of Serine 114 on Atg32 mediates mitophagy
-
Aoki Y, Kanki T, Hirota Y, et al. Phosphorylation of Serine 114 on Atg32 mediates mitophagy. Mol Biol Cell 2011; 22:3206-3217.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3206-3217
-
-
Aoki, Y.1
Kanki, T.2
Hirota, Y.3
-
39
-
-
84858200622
-
Barriers to male transmission of mitochondrial DNA in sperm development
-
DeLuca SZ, OFarrell PH. Barriers to male transmission of mitochondrial DNA in sperm development. Dev Cell 2012; 22:660-668.
-
(2012)
Dev Cell
, vol.22
, pp. 660-668
-
-
Deluca, S.Z.1
Ofarrell, P.H.2
-
40
-
-
84881410399
-
Unique insights into maternal mitochondrial inheritance in mice
-
Luo SM, Ge ZJ, Wang ZW, et al. Unique insights into maternal mitochondrial inheritance in mice. Proc Natl Acad Sci USA 2013; 110:13038-13043.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 13038-13043
-
-
Luo, S.M.1
Ge, Z.J.2
Wang, Z.W.3
-
41
-
-
82255192465
-
Degradation of paternal mitochondria by fertilization-triggered autophagy in Celegans embryos
-
Sato M, Sato K. Degradation of paternal mitochondria by fertilization-triggered autophagy in Celegans embryos. Science 2011, 334:1141-1144.
-
(2011)
Science
, vol.334
, pp. 1141-1144
-
-
Sato, M.1
Sato, K.2
-
42
-
-
82255183165
-
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission
-
Rawi SA, Louvet-Valle S, Djeddi A, et al. Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission. Science 2011; 334:1144-1147.
-
(2011)
Science
, vol.334
, pp. 1144-1147
-
-
Rawi, S.A.1
Louvet-Valle, S.2
Djeddi, A.3
-
43
-
-
82655187112
-
Elimination of paternal mitochondria through the lysosomal degradation pathway in Celegans
-
Zhou QH, Li HM, Xue D. Elimination of paternal mitochondria through the lysosomal degradation pathway in Celegans. Cell Res 2011; 21:1662-1669.
-
(2011)
Cell Res
, vol.21
, pp. 1662-1669
-
-
Zhou, Q.H.1
Li, H.M.2
Xue, D.3
-
44
-
-
0021869570
-
Morphogenesis and fate of the residual body in human spermiogenesis
-
Breucker H, Schafer E, Holstein AF. Morphogenesis and fate of the residual body in human spermiogenesis. Cell Tis sue Res 1985; 240:303-309.
-
(1985)
Cell Tis Sue Res
, vol.240
, pp. 303-309
-
-
Breucker, H.1
Schafer, E.2
Holstein, A.F.3
-
45
-
-
0023029758
-
The phagocytic function of Sertoli cells: A morphological, biochemical, and endocrinological study of lysosomes and acid phosphatase localization in the rat testis
-
Chemes H. The phagocytic function of Sertoli cells: a morphological, biochemical, and endocrinological study of lysosomes and acid phosphatase localization in the rat testis. Endocrinology 1986; 119:1673-1681.
-
(1986)
Endocrinology
, vol.119
, pp. 1673-1681
-
-
Chemes, H.1
-
46
-
-
38449107711
-
Spermatogenesis
-
Feb
-
LHernault SW. Spermatogenesis. WormBook 2006 Feb 20:1-14.
-
(2006)
WormBook
, vol.20
, pp. 1-14
-
-
Lhernault, S.W.1
-
48
-
-
0020789356
-
The initiation of spermiogenesis in the nematode Caenorhabditis elegans
-
Ward S, Hogan E, Nelson GA. The initiation of spermiogenesis in the nematode Caenorhabditis elegans. Dev Biol 1983; 98:70-79
-
(1983)
Dev Biol
, vol.98
, pp. 70-79
-
-
Ward, S.1
Hogan, E.2
Nelson, G.A.3
-
49
-
-
84870024590
-
Residual body removal during spermatogenesis in Celegans requires genes that mediate cell corpse clearance
-
Huang J, Wang HB, Chen YY, Wang XC, Zhang H. Residual body removal during spermatogenesis in Celegans requires genes that mediate cell corpse clearance. Development 2012; 139:4613-4622.
-
(2012)
Development
, vol.139
, pp. 4613-4622
-
-
Huang, J.1
Wang, H.B.2
Chen, Y.Y.3
Wang, X.C.4
Zhang, H.5
-
50
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan MA, Dillon CP, Tait SW, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007; 450:1253-1257.
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
Dillon, C.P.2
Tait, S.W.3
-
51
-
-
80054825045
-
Microtubuleassociated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
-
Martinez J, Almendinger J, Oberst A, et al. Microtubuleassociated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells. Proc Natl Acad Sci USA 2011; 108:17396-17401.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17396-17401
-
-
Martinez, J.1
Almendinger, J.2
Oberst, A.3
-
52
-
-
80455122654
-
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
-
Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol 2011; 13:1335-1343.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1335-1343
-
-
Florey, O.1
Kim, S.E.2
Sandoval, C.P.3
Haynes, C.M.4
Overholtzer, M.5
-
53
-
-
33847404337
-
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
-
Qu XP, Zou ZJ, Sun QH, et al. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 2007; 128:931-946.
-
(2007)
Cell
, vol.128
, pp. 931-946
-
-
Qu, X.P.1
Zou, Z.J.2
Sun, Q.H.3
-
54
-
-
47249164452
-
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
-
Melln MA, de la Rosa EJ, Boya P. The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium. Cell Death Differ 2008; 15:1279-1290.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1279-1290
-
-
Melln, M.A.1
De La Rosa, E.J.2
Boya, P.3
-
55
-
-
0020858899
-
The embryonic cell lineage of the nematode Caenorhabditis elegans
-
Sulston J E, Schierenberg E, White JG, Thomson JN, The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol 1983; 100:64-119.
-
(1983)
Dev Biol
, vol.100
, pp. 64-119
-
-
Sulston, J.E.1
Schierenberg, E.2
White, J.G.3
Thomson, J.N.4
-
56
-
-
52949150791
-
Phagosome maturation during the removal of apoptotic cells: Receptors lead the way
-
Zhou Z, Yu X. Phagosome maturation during the removal of apoptotic cells: receptors lead the way. Trends Cell Biol 2008; 18:474-485.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 474-485
-
-
Zhou, Z.1
Yu, X.2
-
58
-
-
42549167544
-
Celegans Rab GTPase 2 is required for the degradation of apoptotic cells
-
Lu Q, Zhang Y, Hu T, Guo P, Li W, Wang X. Celegans Rab GTPase 2 is required for the degradation of apoptotic cells. Development 2008; 135:1069-1080.
-
(2008)
Development
, vol.135
, pp. 1069-1080
-
-
Lu, Q.1
Zhang, Y.2
Hu, T.3
Guo, P.4
Li, W.5
Wang, X.6
-
59
-
-
78149270305
-
Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation
-
Guo P, Hu T, Zhang J, Jiang S, Wang X. Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation. Proc Natl Acad Sci USA 2010; 107:18016-18021.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18016-18021
-
-
Guo, P.1
Hu, T.2
Zhang, J.3
Jiang, S.4
Wang, X.5
-
60
-
-
43049147117
-
A pathway for phagosome maturation during engulfment of apoptotic cells
-
Kinchen JM, Doukoumetzidis K, Almendinger J, et al. A pathway for phagosome maturation during engulfment of apoptotic cells. Nat Cell Biol 2008; 10:556-566.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 556-566
-
-
Kinchen, J.M.1
Doukoumetzidis, K.2
Almendinger, J.3
-
61
-
-
84863012304
-
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells
-
Lu N, Shen Q, Mahoney TR, Neukomm LJ, Wang Y, Zhou Z. Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells. PLoS Biol 2012; 10:e1001245.
-
(2012)
PLoS Biol
, vol.10
-
-
Lu, N.1
Shen, Q.2
Mahoney, T.R.3
Neukomm, L.J.4
Wang, Y.5
Zhou, Z.6
-
62
-
-
84873628958
-
Autophagy genes function in apoptotic cell corpse clearance during Celegans embryonic development
-
Huang SY, Jia KL, Wang Y, Zhou Z, Levine B. Autophagy genes function in apoptotic cell corpse clearance during Celegans embryonic development. Autophagy 2013; 9:138-149.
-
(2013)
Autophagy
, vol.9
, pp. 138-149
-
-
Huang, S.Y.1
Jia, K.L.2
Wang, Y.3
Zhou, Z.4
Levine, B.5
-
63
-
-
84890848364
-
Autophagy genes coordinate with the class II PI3 kinase PIKI-1 to regulate maturation of apoptotic cell-containing phagosomes in Celegans
-
in press
-
Cheng SY, Wu YW, Lu Q, Yan JC, Zhang H, Wang XC. Autophagy genes coordinate with the class II PI3 kinase PIKI-1 to regulate maturation of apoptotic cell-containing phagosomes in Celegans. Autophagy 2013; 9: (in press).
-
(2013)
Autophagy
, vol.9
-
-
Cheng, S.Y.1
Wu, Y.W.2
Lu, Q.3
Yan, J.C.4
Zhang, H.5
Wang, X.C.6
-
64
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
Carthew RW, Sontheimer EJ. Origins and mechanisms of miRNAs and siRNAs. Cell 2009; 136:642-655.
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
65
-
-
34548490990
-
GW182 family proteins are crucial for microRNA-mediated gene silencing
-
Ding L, Han M. GW182 family proteins are crucial for microRNA-mediated gene silencing. Trends Cell Biol 2007; 17:411-416.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 411-416
-
-
Ding, L.1
Han, M.2
-
66
-
-
79960924567
-
MicroRNAs and developmental timing
-
Ambros V. MicroRNAs and developmental timing. Curr Opin Genet Dev 2011; 21:511-517.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 511-517
-
-
Ambros, V.1
-
67
-
-
0033634943
-
The lin-41 RBCC gene acts in the Celegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
-
Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the Celegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000; 5:659-669.
-
(2000)
Mol Cell
, vol.5
, pp. 659-669
-
-
Slack, F.J.1
Basson, M.2
Liu, Z.3
Ambros, V.4
Horvitz, H.R.5
Ruvkun, G.6
-
68
-
-
24144494563
-
The let- 7 MicroRNA family members mir-48, mir-84 and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
-
Abbott AL, Alvarez-Saavedra E, Miska EA, et al. The let- 7 MicroRNA family members mir-48, mir-84 and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell 2005; 3:403-414.
-
(2005)
Dev Cell
, vol.3
, pp. 403-414
-
-
Abbott, A.L.1
Alvarez-Saavedra, E.2
Miska, E.A.3
-
69
-
-
24144467823
-
Regulatory mutations of mir-48, a Celegans let-7 family microRNA, cause developmental timing defects
-
Li M, Jones-Rhoades MW, Lau NC, Bartel DP, Rougvie AE. Regulatory mutations of mir-48, a Celegans let-7 family microRNA, cause developmental timing defects. Dev Cell 2005; 9:415-422.
-
(2005)
Dev Cell
, vol.9
, pp. 415-422
-
-
Li, M.1
Jones-Rhoades, M.W.2
Lau, N.C.3
Bartel, D.P.4
Rougvie, A.E.5
-
70
-
-
23744492247
-
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in Celegans
-
Ding L, Spencer A, Morita K, Han M. The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in Celegans. Mol Cell 2005; 19:437-447.
-
(2005)
Mol Cell
, vol.19
, pp. 437-447
-
-
Ding, L.1
Spencer, A.2
Morita, K.3
Han, M.4
-
71
-
-
36249012075
-
Systematic identification of Celegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2
-
Zhang L, Ding L, Cheung TH, et al. Systematic identification of Celegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell 2007; 28:598-613.
-
(2007)
Mol Cell
, vol.28
, pp. 598-613
-
-
Zhang, L.1
Ding, L.2
Cheung, T.H.3
-
72
-
-
84878621387
-
Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in Celegans
-
Zhang PP, Zhang H. Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in Celegans. EMBO Rep 2013; 14:568-576.
-
(2013)
EMBO Rep
, vol.14
, pp. 568-576
-
-
Zhang, P.P.1
Zhang, H.2
-
73
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005; 120:635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
74
-
-
0031767247
-
Genetics of RAS signaling in Celegans
-
Sternberg PW, Han M. Genetics of RAS signaling in Celegans. Trends Genet 1998; 14:466-472.
-
(1998)
Trends Genet
, vol.14
, pp. 466-472
-
-
Sternberg, P.W.1
Han, M.2
-
75
-
-
0347357618
-
A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
-
Johnston RJ, Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 2003; 426:845-849.
-
(2003)
Nature
, vol.426
, pp. 845-849
-
-
Johnston, R.J.1
Hobert, O.2
-
76
-
-
84870601009
-
Selective autophagy degrades DICER and AGO2 and regulates miRNA activity
-
Gibbings D, Mostowy S, Jay F, Schwab Y, Cossar P, Voinnet O. Selective autophagy degrades DICER and AGO2 and regulates miRNA activity. Nat Cell Biol 2012; 14:1314-1321.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1314-1321
-
-
Gibbings, D.1
Mostowy, S.2
Jay, F.3
Schwab, Y.4
Cossar, P.5
Voinnet, O.6
-
77
-
-
84866885431
-
Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway
-
Derrien B, Baumbergera N, Schepetilnikova M, et al. Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway. Proc Natl Acad Sci USA 2012; 109:15942-15946.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 15942-15946
-
-
Derrien, B.1
Baumbergera, N.2
Schepetilnikova, M.3
-
78
-
-
34548421950
-
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation
-
Kang C, You YJ, Avery L. Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation. Genes Dev 2007; 21:2161-2171.
-
(2007)
Genes Dev
, vol.21
, pp. 2161-2171
-
-
Kang, C.1
You, Y.J.2
Avery, L.3
-
79
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in Celegans
-
Melndez A, Tallczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in Celegans. Science 2003; 301:1387-1391.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melndez, A.1
Tallczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
80
-
-
70449769682
-
Lipid droplets finally get a little R-E-S-P-E-C-T
-
Farese RV Jr, Walther TC. Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 2009; 139:855-860.
-
(2009)
Cell
, vol.139
, pp. 855-860
-
-
Farese Jr., R.V.1
Walther, T.C.2
-
81
-
-
40849145708
-
Lipid droplets in lipogenesis and lipolysis
-
Ducharme NA, Bickel PE. Lipid droplets in lipogenesis and lipolysis. Endocrinology 2008; 149:942-949.
-
(2008)
Endocrinology
, vol.149
, pp. 942-949
-
-
Ducharme, N.A.1
Bickel, P.E.2
-
82
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh R, Kaushik S, Wang YJ, et al. Autophagy regulates lipid metabolism. Nature 2009; 458:1131-1135.
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.J.3
-
83
-
-
70449448312
-
Autophagy regulates adipose mass and differentiation in mice
-
Singh R, Xiang YQ, Wang YJ, et al. Autophagy regulates adipose mass and differentiation in mice. J Clin Invest 2009; 119:3329-3339.
-
(2009)
J Clin Invest
, vol.119
, pp. 3329-3339
-
-
Singh, R.1
Xiang, Y.Q.2
Wang, Y.J.3
-
84
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
-
Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin SK. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci USA 2009; 106:19860-19865.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.K.6
-
86
-
-
80053312481
-
Autophagy and lipid metabolism coordinately modulate life span in germline-less Celegans
-
Lapierre LR, Gelino S, Melndez A, Hansen M. Autophagy and lipid metabolism coordinately modulate life span in germline-less Celegans. Curr Biol 2011; 21:1507-1514.
-
(2011)
Curr Biol
, vol.21
, pp. 1507-1514
-
-
Lapierre, L.R.1
Gelino, S.2
Melndez, A.3
Hansen, M.4
-
87
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in Celegans
-
Wang MC, ORourke EJ, Ruvkun G. Fat metabolism links germline stem cells and longevity in Celegans. Science 2008; 322:957-960.
-
(2008)
Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
Orourke, E.J.2
Ruvkun, G.3
-
88
-
-
84874271499
-
Polyunsaturated fatty acids extend life span through the activation of autophagy
-
ORourke EJ, Kuballa P, Xavier R, Ruvkun G. ?-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. Genes Dev 2013; 27:429-440.
-
(2013)
Genes Dev
, vol.27
, pp. 429-440
-
-
Orourke, E.J.1
Kuballa, P.2
Xavier, R.3
Ruvkun, G.4
-
89
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in Celegans
-
Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in Celegans. PLoS Genet 2008; 4:e24.
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
90
-
-
84878533962
-
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
-
ORourke EJ, Ruvkun G. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Nat Cell Biol 2013; 15:668-676.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 668-676
-
-
Orourke, E.J.1
Ruvkun, G.2
-
91
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
Settembre C, Di Malta C, Polito VA, et al. TFEB links autophagy to lysosomal biogenesis. Science 2011; 332:1429-1433.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
-
92
-
-
84883063789
-
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
-
Lapierre LR, De Magalhaes Filho CD, McQuary PR, et al. The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans. Nat Commun 2013; 4:2267.
-
(2013)
Nat Commun
, vol.4
, pp. 2267
-
-
Lapierre, L.R.1
De Magalhaes Filho, C.D.2
McQuary, P.R.3
-
93
-
-
84878606239
-
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
-
Settembre C, De Cegli R, Mansueto G, et al. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop. Nat Cell Biol 2013; 15:647-658.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 647-658
-
-
Settembre, C.1
De Cegli, R.2
Mansueto, G.3
-
94
-
-
78649901091
-
Alternative cell death mechanisms in development and beyond
-
Yuan J, Kroemer G. Alternative cell death mechanisms in development and beyond. Genes Dev 2010; 24:2592-2602.
-
(2010)
Genes Dev
, vol.24
, pp. 2592-2602
-
-
Yuan, J.1
Kroemer, G.2
-
95
-
-
10344262564
-
Role of Bcl- 2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl- 2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6:1221-1228.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
-
96
-
-
78649634635
-
Distinct death mechanisms in Drosophila development
-
Ryoo HD, Baehrecke EH. Distinct death mechanisms in Drosophila development. Curr Opin Cell Biol 2010; 22:889-895.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 889-895
-
-
Ryoo, H.D.1
Baehrecke, E.H.2
-
97
-
-
0842279780
-
Caspases function in autophagic programmed cell death in Drosophila
-
Martin DN, Baehrecke EH. Caspases function in autophagic programmed cell death in Drosophila. Development 2004; 131:275-284.
-
(2004)
Development
, vol.131
, pp. 275-284
-
-
Martin, D.N.1
Baehrecke, E.H.2
-
98
-
-
36849088609
-
Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
-
Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 2007; 131:1137-1148.
-
(2007)
Cell
, vol.131
, pp. 1137-1148
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
99
-
-
65249106660
-
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
-
Nezis IP, Lamark T, Velentzas AD, et al. Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy. Autophagy 2009; 5:298-302.
-
(2009)
Autophagy
, vol.5
, pp. 298-302
-
-
Nezis, I.P.1
Lamark, T.2
Velentzas, A.D.3
-
100
-
-
70350571244
-
Autophagy, not apoptosis, is essential for midgut cell death in Drosophila
-
Denton D, Shravage B, Simin R, et al. Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. Curr Biol 2009; 19:1741-1746.
-
(2009)
Curr Biol
, vol.19
, pp. 1741-1746
-
-
Denton, D.1
Shravage, B.2
Simin, R.3
-
101
-
-
38549161105
-
Programmed cell death
-
Oct
-
Conradt B, Xue D. Programmed cell death. WormBook 2005; Oct 6:1-13.
-
(2005)
WormBook
, vol.6
, pp. 1-13
-
-
Conradt, B.1
Xue, D.2
-
103
-
-
0033026027
-
Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline
-
Gumienny TL, Lambie E, Hartwieg E, Horvitz HR, Hengartner MO. Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development 1999; 126:1011-1022.
-
(1999)
Development
, vol.126
, pp. 1011-1022
-
-
Gumienny, T.L.1
Lambie, E.2
Hartwieg, E.3
Horvitz, H.R.4
Hengartner, M.O.5
-
104
-
-
85047687755
-
Autophagy activity contributes to programmed cell death in Caenorhabditis elegans
-
In press
-
Wang HB, Lu Q, Cheng SY, Wang XC, Zhang H. Autophagy activity contributes to programmed cell death in Caenorhabditis elegans. Autophagy 2013; 9: (in press).
-
(2013)
Autophagy
, vol.9
-
-
Wang, H.B.1
Lu, Q.2
Cheng, S.Y.3
Wang, X.C.4
Zhang, H.5
-
105
-
-
0035849886
-
Phagocytosis promotes programmed cell death in Celegans
-
Reddien PW, Cameron S, Horvitz HR. Phagocytosis promotes programmed cell death in Celegans. Nature 2001; 412:198-202.
-
(2001)
Nature
, vol.412
, pp. 198-202
-
-
Reddien, P.W.1
Cameron, S.2
Horvitz, H.R.3
-
106
-
-
0035849895
-
Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
-
Hoeppner DJ, Hengartner MO, Schnabel R. Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature 2001; 412:202-206.
-
(2001)
Nature
, vol.412
, pp. 202-206
-
-
Hoeppner, D.J.1
Hengartner, M.O.2
Schnabel, R.3
-
107
-
-
0017618537
-
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
-
Sulston JE, Horvitz HR. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol 1977; 56:110-156.
-
(1977)
Dev Biol
, vol.56
, pp. 110-156
-
-
Sulston, J.E.1
Horvitz, H.R.2
|