-
1
-
-
33749056809
-
ALS: a disease of motor neurons and their nonneuronal neighbors
-
Boillée, S., C. Vande Velde, and D.W. Cleveland. 2006. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron. 52:39-59. http://dx.doi.org/10.1016/j.neuron.2006.09.018
-
(2006)
Neuron
, vol.52
, pp. 39-59
-
-
Boillée, S.C.1
Vande Velde, C.2
Cleveland, D.W.3
-
2
-
-
83455173649
-
Autophagy proteins regulate the secretory component of osteoclastic bone resorption
-
DeSelm, C.J., B.C. Miller, W. Zou, W.L. Beatty, E. van Meel, Y. Takahata, J. Klumperman, S.A. Tooze, S.L. Teitelbaum, and H.W. Virgin. 2011. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev. Cell. 21:966-974. http://dx.doi.org/10.1016/j.devcel.2011.08.016
-
(2011)
Dev. Cell
, vol.21
, pp. 966-974
-
-
DeSelm, C.J.1
Miller, B.C.2
Zou, W.3
Beatty, W.L.4
Van Meel, E.5
Takahata, Y.6
Klumperman, J.7
Tooze, S.A.8
Teitelbaum, S.L.9
Virgin, H.W.10
-
3
-
-
80755163102
-
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
-
Ferraiuolo, L., J. Kirby, A.J. Grierson, M. Sendtner, and P.J. Shaw. 2011. Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat. Rev. Neurol. 7:616-630. http://dx.doi.org/10.1038/nrneurol.2011.152
-
(2011)
Nat. Rev. Neurol
, vol.7
, pp. 616-630
-
-
Ferraiuolo, L.1
Kirby, J.2
Grierson, A.J.3
Sendtner, M.4
Shaw, P.J.5
-
4
-
-
35948983328
-
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
-
Filimonenko, M., S. Stuffers, C. Raiborg, A. Yamamoto, L. Malerød, E.M. Fisher, A. Isaacs, A. Brech, H. Stenmark, and A. Simonsen. 2007. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J. Cell Biol. 179:485-500. http://dx.doi.org/10.1083/jcb.200702115
-
(2007)
J. Cell Biol
, vol.179
, pp. 485-500
-
-
Filimonenko, M.1
Stuffers, S.2
Raiborg, C.3
Yamamoto, A.4
Malerød, L.5
Fisher, E.M.6
Isaacs, A.7
Brech, A.8
Stenmark, H.9
Simonsen, A.10
-
5
-
-
18244393223
-
A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q
-
Hand, C.K., J. Khoris, F. Salachas, F. Gros-Louis, A.A. Lopes, V. Mayeux-Portas, C.G. Brewer, R.H. Brown Jr., V. Meininger, W. Camu, and G.A. Rouleau. 2002. A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q. Am. J. Hum. Genet. 70:251-256. http://dx.doi.org/ 10.1086/337945
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 251-256
-
-
Hand, C.K.1
Khoris, J.2
Salachas, F.3
Gros-Louis, F.4
Lopes, A.A.5
Mayeux-Portas, V.6
Brewer, C.G.7
Brown Jr., R.H.8
Meininger, V.9
Camu, W.10
Rouleau, G.A.11
-
6
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara, T., K. Nakamura, M. Matsui, A. Yamamoto, Y. Nakahara, R. Suzuki-Migishima, M. Yokoyama, K. Mishima, I. Saito, H. Okano, and N. Mizushima. 2006. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature. 441:885-889. http://dx.doi .org/10.10 38/nature04724
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
7
-
-
0032491408
-
Genetic classification of primary neurodegenerative disease
-
Hardy, J., and K. Gwinn-Hardy. 1998. Genetic classification of primary neurodegenerative disease. Science. 282:1075-1079. http://dx.doi.org/ 10.1126/science.282.5391.1075
-
(1998)
Science
, vol.282
, pp. 1075-1079
-
-
Hardy, J.1
Gwinn-Hardy, K.2
-
8
-
-
78649941297
-
Exome sequencing reveals VCP mutations as a cause of familial ALS
-
ITALSGEN Consortium
-
Johnson, J.O., J. Mandrioli, M. Benatar, Y. Abramzon, V.M. Van Deerlin, J.Q. Trojanowski, J.R. Gibbs, M. Brunetti, S. Gronka, J. Wuu, et al; ITALSGEN Consortium. 2010. Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron. 68:857-864. http://dx.doi.org/ 10.1016/j.neuron.2010.11.036
-
(2010)
Neuron
, vol.68
, pp. 857-864
-
-
Johnson, J.O.1
Mandrioli, J.2
Benatar, M.3
Abramzon, Y.4
Van Deerlin, V.M.5
Trojanowski, J.Q.6
Gibbs, J.R.7
Brunetti, M.8
Gronka, S.9
Wuu, J.10
-
9
-
-
74049124412
-
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
-
Ju, J.S., R.A. Fuentealba, S.E. Miller, E. Jackson, D. Piwnica-Worms, R.H. Baloh, and C.C. Weihl. 2009. Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease. J. Cell Biol. 187:875-888. http://dx.doi.org/10.1083/jcb.200908115
-
(2009)
J. Cell Biol
, vol.187
, pp. 875-888
-
-
Ju, J.S.1
Fuentealba, R.A.2
Miller, S.E.3
Jackson, E.4
Piwnica-Worms, D.5
Baloh, R.H.6
Weihl, C.C.7
-
10
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu, M., S. Waguri, T. Chiba, S. Murata, J. Iwata, I. Tanida, T. Ueno, M. Koike, Y. Uchiyama, E. Kominami, and K. Tanaka. 2006. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature. 441:880-884. http://dx.doi.org/10.1038/nature04723
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
Tanaka, K.11
-
11
-
-
34548492271
-
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
-
Lee, J.A., A. Beigneux, S.T. Ahmad, S.G. Young, and F.B. Gao. 2007. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr. Biol. 17:1561-1567. http://dx.doi.org/10.1016/j.cub.2007.07.029
-
(2007)
Curr. Biol
, vol.17
, pp. 1561-1567
-
-
Lee, J.A.1
Beigneux, A.2
Ahmad, S.T.3
Young, S.G.4
Gao, F.B.5
-
12
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine, B., and G. Kroemer. 2008. Autophagy in the pathogenesis of disease. Cell. 132:27-42. http://dx.doi.org/10.1016/j.cell.2007.12.018
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
13
-
-
67549139908
-
Vesicular trafficking and autophagosome formation
-
Longatti, A., and S.A. Tooze. 2009. Vesicular trafficking and autophagosome formation. Cell Death Differ. 16:956-965. http://dx.doi.org/10.1038/ cdd.2009.39
-
(2009)
Cell Death Differ
, vol.16
, pp. 956-965
-
-
Longatti, A.1
Tooze, S.A.2
-
14
-
-
80051474094
-
The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes
-
Lu, Q., P.G. Yang, X.X. Huang, W.Q. Hu, B. Guo, F. Wu, L. Lin, A.L. Kovács, L. Yu, and H. Zhang. 2011. The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. Dev. Cell. 21:343-357. http://dx.doi.org/10.1016/j.devcel.2011.06.024
-
(2011)
Dev. Cell
, vol.21
, pp. 343-357
-
-
Lu, Q.1
Yang, P.G.2
Huang, X.X.3
Hu, W.Q.4
Guo, B.5
Wu, F.6
Lin, L.7
Kovács, A.L.8
Yu, L.9
Zhang, H.10
-
15
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima, N., T. Yoshimori, and B. Levine. 2010. Methods in mammalian autophagy research. Cell. 140:313-326. http://dx.doi.org/10.1016/j.cell .2010.01.028
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
16
-
-
67649467294
-
Dynamics and diversity in autophagy mechanisms: lessons from yeast
-
Nakatogawa, H., K. Suzuki, Y. Kamada, and Y. Ohsumi. 2009. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat. Rev. Mol. Cell Biol. 10:458-467. http://dx.doi.org/10.1038/nrm2708
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 458-467
-
-
Nakatogawa, H.1
Suzuki, K.2
Kamada, Y.3
Ohsumi, Y.4
-
17
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann, M., D.M. Sampathu, L.K. Kwong, A.C. Truax, M.C. Micsenyi, T.T. Chou, J. Bruce, T. Schuck, M. Grossman, C.M. Clark, et al. 2006. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science. 314:130-133. http://dx.doi.org/10.1126/ science.1134108
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
-
18
-
-
84866144210
-
Dysregulation of the autophagy- endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases
-
Otomo, A., L. Pan, and S. Hadano. 2012. Dysregulation of the autophagy- endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases. Neurol. Res. Int. 2012:498428.
-
(2012)
Neurol. Res. Int.
, vol.2012
, pp. 498428
-
-
Otomo, A.1
Pan, L.2
Hadano, S.3
-
19
-
-
33749006845
-
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
-
MRC Proteomics in ALS Study; FReJA Consortium
-
Parkinson, N., P.G. Ince, M.O. Smith, R. Highley, G. Skibinski, P.M. Andersen, K.E. Morrison, H.S. Pall, O. Hardiman, J. Collinge, et al; MRC Proteomics in ALS Study; FReJA Consortium. 2006. ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology. 67:1074-1077. http://dx.doi.org/10.1212/01 .wnl.0000231510.89311.8b
-
(2006)
Neurology
, vol.67
, pp. 1074-1077
-
-
Parkinson, N.1
Ince, P.G.2
Smith, M.O.3
Highley, R.4
Skibinski, G.5
Andersen, P.M.6
Morrison, K.E.7
Pall, H.S.8
Hardiman, O.9
Collinge, J.10
-
20
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
-
Pasinelli, P., and R.H. Brown. 2006. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7:710-723. http://dx.doi.org/10.1038/nrn1971
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
21
-
-
77953713630
-
C. elegans screen identifies autophagy genes specific to multicellular organisms
-
Tian, Y., Z.P. Li, W.Q. Hu, H.Y. Ren, E. Tian, Y. Zhao, Q. Lu, X.X. Huang, P.G. Yang, X. Li, et al. 2010. C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell. 141:1042-1055. http://dx.doi .org/10.1016/j.cell.2010.04.034
-
(2010)
Cell
, vol.141
, pp. 1042-1055
-
-
Tian, Y.1
Li, Z.P.2
Hu, W.Q.3
Ren, H.Y.4
Tian, E.5
Zhao, Y.6
Lu, Q.7
Huang, X.X.8
Yang, P.G.9
Li, X.10
-
22
-
-
77952533111
-
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
-
Tresse, E., F.A. Salomons, J. Vesa, L.C. Bott, V. Kimonis, T.P. Yao, N.P. Dantuma, and J.P. Taylor. 2010. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy. 6:217-227. http://dx.doi.org/ 10.4161/auto.6.2.11014
-
(2010)
Autophagy
, vol.6
, pp. 217-227
-
-
Tresse, E.1
Salomons, F.A.2
Vesa, J.3
Bott, L.C.4
Kimonis, V.5
Yao, T.P.6
Dantuma, N.P.7
Taylor, J.P.8
-
23
-
-
84857844643
-
Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets
-
Velikkakath, A.K., T. Nishimura, E. Oita, N. Ishihara, and N. Mizushima. 2012. Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Mol. Biol. Cell. 23:896-909. http://dx.doi.org/10.1091/mbc .E11-09-0785
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 896-909
-
-
Velikkakath, A.K.1
Nishimura, T.2
Oita, E.3
Ishihara, N.4
Mizushima, N.5
-
24
-
-
79953647105
-
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis
-
Zhang, X., L. Li, S. Chen, D. Yang, Y. Wang, X. Zhang, Z. Wang, and W. Le. 2011. Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Autophagy. 7:412-425. http://dx.doi.org/10.4161/auto.7.4.14541
-
(2011)
Autophagy
, vol.7
, pp. 412-425
-
-
Zhang, X.1
Li, L.2
Chen, S.3
Yang, D.4
Wang, Y.5
Zhang, X.6
Wang, Z.7
Le, W.8
-
25
-
-
84871282033
-
The p53-induced gene Ei24 is an essential component of the basal autophagy pathway
-
Zhao, Y.G., H. Zhao, L. Miao, L. Wang, F. Sun, and H. Zhang. 2012. The p53-induced gene Ei24 is an essential component of the basal autophagy pathway. J. Biol. Chem. 287:42053-42063. http://dx.doi.org/10.1074/jbc .M112.415968
-
(2012)
J. Biol. Chem
, vol.287
, pp. 42053-42063
-
-
Zhao, Y.G.1
Zhao, H.2
Miao, L.3
Wang, L.4
Sun, F.5
Zhang, H.6
|