Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype

Hypertension

Volumn 44, Issue 5, 2004, Pages 649-654

  Feoktistov, Igor ^a   Ryzhov, Sergey ^a,b   Zhong, Hongyan ^c   Goldstein, Anna E ^a   Matafonov, Anton ^a,b   Zeng, Dewan ^c   Biaggioni, Italo ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CV THERAPEUTICS INC   (United States)

Author keywords

Adenosine; Endothelium; Endothelium derived factors; Hypoxia; Muscle, smooth; Receptors, purinergic; Vasculature

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR; BETA ACTIN; CVT 6694; CYCLIC AMP; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; HYPOXIA; MOLECULAR MECHANICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REPORTER GENE; SMOOTH MUSCLE FIBER; UPREGULATION;

CELL HYPOXIA; CELLS, CULTURED; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; NUCLEAR PROTEINS; PHENOTYPE; RECEPTOR, ADENOSINE A2B; RECEPTORS, PURINERGIC P1; RNA, MESSENGER; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 7244234161     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000144800.21037.a5     Document Type: Article

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