Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors

Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2000, Pages 1165-1172

  Kim, Yong Chul ^a   Ji, Xiao Duo ^a   Melman, Neli ^a   Linden, Joel ^b   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR; ADENOSINE A2B RECEPTOR ANTAGONIST; ANILIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANILIDES; ANIMALS; CALCIUM; CELL LINE; HUMANS; RADIOLIGAND ASSAY; RATS; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHINES;

EID: 0034704901     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990421v     Document Type: Article

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