Identifying cytochrome P450 functional networks and their allosteric regulatory elements

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Liu, Jin ^a   Tawa, Gregory J ^a   Wallqvist, Anders ^a  

^a U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A; CYTOCHROME P450 2C; CYTOCHROME P450 2D; CYTOCHROME P450 3A;

ALLOSTERISM; ANISOTROPIC THERMAL DIFFUSION; ARTICLE; BINDING SITE; BIOLOGICAL FUNCTIONS; CATALYSIS; CO EVOLUTIONARY ANALYSIS; CONTROLLED STUDY; DIMERIZATION; DRUG TRANSFORMATION; HEME BINDING NETWORK; MEMBRANE BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ALLOSTERIC SITE; BENZOFLAVONES; BIOCATALYSIS; CELL MEMBRANE; COMPUTATIONAL BIOLOGY; CYTOCHROME P-450 ENZYME SYSTEM; EVOLUTION, MOLECULAR; HEME; MOLECULAR DYNAMICS SIMULATION; MUTATION; OXAZINES; PROTEIN CONFORMATION; TEMPERATURE;

EID: 84891687220     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081980     Document Type: Article

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