Structure and dynamics of the membrane-bound cytochrome P450 2C9

PLoS Computational Biology

Volumn 7, Issue 8, 2011, Pages

  Cojocaru, Vlad ^a,b   Balali Mood, Kia ^c,d   Sansom, Mark S P ^c   Wade, Rebecca C ^a  

^a HEIDELBERG INSTITUTE FOR THEORETICAL STUDIES   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d ID Business Solutions   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON TRANSITIONS; MAMMALS; SUBSTRATES;

CYTOCHROME P450 REDUCTASE; CYTOCHROMES P450; DRUG METABOLISMS; ELECTRON TRANSFER; HUMAN CYTOCHROMES P450; MEMBRANE-BOUND; MICROSOMAL MEMBRANES; MONOOXYGENASES; STRUCTURAL-FUNCTIONAL; STRUCTURE AND DYNAMICS;

MEMBRANES;

CYTOCHROME P450 2C9; CYP2C9 PROTEIN, HUMAN; UNSPECIFIC MONOOXYGENASE;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME LOCALIZATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; MEMBRANE BIOLOGY; MEMBRANE PERMEABILITY; MOLECULAR DYNAMICS; PROCESS MODEL; PROTEIN FUNCTION; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; CELL MEMBRANE; CHEMISTRY; HUMAN; METABOLISM; MICROSOME; PLIABILITY; PROTEIN BINDING; PROTEIN CONFORMATION;

MAMMALIA;

ARYL HYDROCARBON HYDROXYLASES; CATALYTIC DOMAIN; CELL MEMBRANE; HUMANS; MICROSOMES; MOLECULAR DYNAMICS SIMULATION; PLIABILITY; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 80052340721     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002152     Document Type: Article

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