Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 25, 2011, Pages 10139-10143

  Strushkevich, Natallia ^a   MacKenzie, Farrell ^a   Cherkesova, Tatyana ^b   Grabovec, Irina ^b   Usanov, Sergey ^b   Park, Hee Won ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

Author keywords

Ferredoxin hemeprotein electron transfer; Fusion protein; Hydroxysteroids; Inner mitochondrial membrane

Indexed keywords

ADRENODOXIN; CHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; HEME; PREGNENOLONE;

ARTICLE; BIOSYNTHESIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; GEOMETRY; HYDROXYLATION; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; STATIC ELECTRICITY; STEREOSPECIFICITY;

ADRENODOXIN; ANIMALS; CATALYTIC DOMAIN; CATTLE; CHOLESTEROL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; HUMANS; MITOCHONDRIA; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; OXIDATION-REDUCTION; PREGNENOLONE; PROTEIN BINDING; PROTEIN CONFORMATION; STATIC ELECTRICITY;

EUKARYOTA;

EID: 79959950838     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1019441108     Document Type: Article

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