Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles

ACS Nano

Volumn 7, Issue 12, 2013, Pages 10834-10849

  Sun, Bingbing ^a   Ji, Zhaoxia ^b   Liao, Yu Pei ^a   Wang, Meiying ^a   Wang, Xiang ^a   Dong, Juyao ^b   Chang, Chong Hyun ^b   Li, Ruibin ^a   Zhang, Haiyuan ^a   Nel, André E ^a,b   Xia, Tian ^a,b  

^a Division of NanoMedicine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alum; aluminum oxyhydroxide; humoral and cellular immune responses; IL 1 ; NLRP3 inflammasome; oxidative stress; vaccine adjuvant

Indexed keywords

ALUM; IMMUNE RESPONSE; INFLAMMASOME; OXYHYDROXIDES; VACCINE ADJUVANTS;

ASPECT RATIO; CELLS; IMMUNE SYSTEM; NANOPARTICLES; NANORODS; OXIDATIVE STRESS; VACCINES;

ALUMINUM;

ALUMINUM; ALUMINUM HYDROXIDE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 1BETA; METAL NANOPARTICLE; NANOTUBE; OVALBUMIN;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; FEMALE; HUMAN; HUMORAL IMMUNITY; INFLAMMATION; INNATE IMMUNITY; LYSOSOME; METABOLISM; MOUSE; NANOTECHNOLOGY; OXIDATIVE STRESS; SURFACE PROPERTY;

ADJUVANTS, IMMUNOLOGIC; ALUMINUM; ALUMINUM HYDROXIDE; ANIMALS; CELL LINE; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNITY, HUMORAL; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-1BETA; LYSOSOMES; METAL NANOPARTICLES; MICE; NANOTECHNOLOGY; NANOTUBES; OVALBUMIN; OXIDATIVE STRESS; SURFACE PROPERTIES;

EID: 84891363798     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn404211j     Document Type: Article

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