C-peptide activates AMPKα and prevents ROS-mediated mitochondrial fission and endothelial apoptosis in diabetes

Diabetes

Volumn 62, Issue 11, 2013, Pages 3851-3862

  Bhatt, Mahendra Prasad ^a   Lim, Young Cheol ^a   Kim, Young Myeong ^a   Ha, Kwon Soo ^a  

^a Kangwon National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; C PEPTIDE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; REACTIVE OXYGEN METABOLITE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC ANGIOPATHY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOSOL; DRUG EFFECT; ENZYME ACTIVATION; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; DRUG EFFECTS;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; C-PEPTIDE; CELLS, CULTURED; CYTOSOL; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; ENZYME ACTIVATION; GLUCOSE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; METFORMIN; MICE; MICE, INBRED C57BL; MITOCHONDRIAL DYNAMICS; REACTIVE OXYGEN SPECIES;

EID: 84891350009     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0039     Document Type: Article

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