Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells: The Role of Protein Kinase C and NAD(P)H-Oxidase Activation

Diabetes

Volumn 52, Issue 11, 2003, Pages 2795-2804

  Quagliaro, Lisa ^a   Piconi, Ludovica ^a   Assaloni, Roberta ^b   Martinelli, Lucia ^b   Motz, Enrico ^b   Ceriello, Antonio ^b  

^a Morpurgo Hofman Research Laboratory on Aging   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; BISINDOLYLMALEIMIDE; GENE PRODUCT; GLUCOSE; LY 379196; MANGANESE SUPEROXIDE DISMUTASE; MANNITOL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN P22PHOX; PROTEIN P47; PROTEIN P67PHOX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETIC MICROANGIOPATHY; DISEASE MARKER; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE OVEREXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; TIME SERIES ANALYSIS; UMBILICAL VEIN;

CELL CULTURE TECHNIQUES; CELLS, CULTURED; DEOXYGUANOSINE; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GLUCOSE; HUMANS; MANNITOL; MESYLATES; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; PROTEIN KINASE C; PYRROLES; TIME FACTORS; TYROSINE; UMBILICAL VEINS;

EID: 0242300561     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.11.2795     Document Type: Article

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