C-peptide prevents hyperglycemia-induced endothelial apoptosis through inhibition of reactive oxygen species-mediated transglutaminase 2 activation

Diabetes

Volumn 62, Issue 1, 2013, Pages 243-253

  Bhatt, Mahendra Prasad ^a,b   Lim, Young Cheol ^a   Hwang, JongYun ^a   Na, SungHun ^a   Kim, Young Myeong ^a   Ha, Kwon Soo ^a  

^a Kangwon National University College of Medicine   (South Korea)

^b Department of Laboratory Medicine   (Nepal)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CALCIUM ION; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CONTINUOUS INFUSION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART; HUMAN; HUMAN CELL; HYPERGLYCEMIA; KIDNEY CORTEX; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; APOPTOSIS; C-PEPTIDE; CALCIUM; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; ENZYME ACTIVATION; GTP-BINDING PROTEINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPERGLYCEMIA; KIDNEY CORTEX; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; REACTIVE OXYGEN SPECIES; STREPTOZOCIN; TRANSGLUTAMINASES;

EID: 84872019417     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0293     Document Type: Article

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