The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation

IUBMB Life

Volumn 65, Issue 12, 2013, Pages 999-1011

  Diakiw, Sonya M ^a,b   D'Andrea, Richard J ^b,c,d,e   Brown, Anna L ^b,c,d,e  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b SA Pathology ^*  (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d Centre for Cancer Biology and Department of Haematology   (Australia)

^e UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

context dependent; KLF5; oncogene; transcription factor; tumour suppressor

Indexed keywords

BETA CATENIN; KRUPPEL LIKE FACTOR 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROGESTERONE RECEPTOR; STEROID HORMONE; SURVIVIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; CANCER INHIBITION; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CELL TRANSFORMATION; DOWN REGULATION; EMBRYONIC STEM CELL; FIBROBLAST; G1 PHASE CELL CYCLE CHECKPOINT; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION REGULATION; GENE REPRESSION; HETEROZYGOSITY LOSS; HUMAN; INTESTINE EPITHELIUM CELL; KERATINOCYTE; LIPID METABOLISM; METASTASIS POTENTIAL; MORPHOGENESIS; NONHUMAN; POINT MUTATION; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN STABILITY; PULMONARY HYPERTENSION; REVIEW; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; SQUAMOUS CELL CARCINOMA; TRANSACTIVATION; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE; WNT SIGNALING PATHWAY;

CONTEXT DEPENDENT; KLF5; ONCOGENE; TRANSCRIPTION FACTOR; TUMOUR SUPPRESSOR;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; NEOPLASMS; ONCOGENES; TUMOR SUPPRESSOR PROTEINS;

EID: 84891276839     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1233     Document Type: Review

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