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Volumn 437, Issue 2, 2011, Pages 323-333

Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells

Author keywords

Breast cancer; Kr ppel like factor 5 (KLF5); Oestrogen; Oestrogen receptor (ER); Oestrogen responsive finger protein (EFP)

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RESPONSIVE FINGER PROTEIN; KRUPPEL LIKE FACTOR 5; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 79959704555     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101388     Document Type: Article
Times cited : (36)

References (49)
  • 1
    • 0021464779 scopus 로고
    • Kruppel, a gene whose activity is required early in the zygotic genome for normal embryonic segmentation
    • Wieschaus, E., Nusslein-Volhard, C. and Kluding, H. (1984) Kruppel, a gene whose activity is required early in the zygotic genome for normal embryonic segmentation. Dev. Biol. 104, 172-186
    • (1984) Dev. Biol. , vol.104 , pp. 172-186
    • Wieschaus, E.1    Nusslein-Volhard, C.2    Kluding, H.3
  • 2
    • 0027299626 scopus 로고
    • cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2
    • Sogawa, K., Imataka, H., Yamasaki, Y., Kusume, H., Abe, H. and Fujii-Kuriyama, Y. (1993) cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2. Nucleic Acids Res. 21, 1527-1532
    • (1993) Nucleic Acids Res , vol.21 , pp. 1527-1532
    • Sogawa, K.1    Imataka, H.2    Yamasaki, Y.3    Kusume, H.4    Abe, H.5    Fujii-Kuriyama, Y.6
  • 5
    • 33644871873 scopus 로고    scopus 로고
    • Kruppel-like factor 5 is an important mediator for lipopolysaccharide- induced proinflammatory response in intestinal epithelial cells
    • Chanchevalap, S., Nandan, M. O., McConnell, B. B., Charrier, L., Merlin, D., Katz, J. P. and Yang, V. W. (2006) Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells. Nucleic Acids Res. 34, 1216-1223
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1216-1223
    • Chanchevalap, S.1    Nandan, M.O.2    McConnell, B.B.3    Charrier, L.4    Merlin, D.5    Katz, J.P.6    Yang, V.W.7
  • 6
  • 7
    • 1842425769 scopus 로고    scopus 로고
    • Intestinal tumor progression is associated with altered function of KLF5
    • Bateman, N. W., Tan, D., Pestell, R. G., Black, J. D. and Black, A. R. (2004) Intestinal tumor progression is associated with altered function of KLF5. J. Biol. Chem. 279, 12093-12101
    • (2004) J. Biol. Chem. , vol.279 , pp. 12093-12101
    • Bateman, N.W.1    Tan, D.2    Pestell, R.G.3    Black, J.D.4    Black, A.R.5
  • 8
    • 67650555438 scopus 로고    scopus 로고
    • Acetylation of KLF5 alters the assembly of P15 transcription factors in TGFβ-mediated induction in epithelial cells
    • Guo, P., Zhao, K. W., Dong, X. Y., Sun, X. and Dong, J. T. (2009) Acetylation of KLF5 alters the assembly of P15 transcription factors in TGFβ-mediated induction in epithelial cells. J. Biol. Chem. 284, 18184-18193
    • (2009) J. Biol. Chem. , vol.284 , pp. 18184-18193
    • Guo, P.1    Zhao, K.W.2    Dong, X.Y.3    Sun, X.4    Dong, J.T.5
  • 9
    • 70350502092 scopus 로고    scopus 로고
    • Opposing effects of KLF5 on the transcription of Myc in epithelial proliferation in the context of TGFβ
    • Guo, P., Dong, X. Y., Zhao, K. W., Sun, X., Li, Q. and Dong, J. T. (2009) Opposing effects of KLF5 on the transcription of Myc in epithelial proliferation in the context of TGFβ. J. Biol. Chem. 284, 28243-28252
    • (2009) J. Biol. Chem. , vol.284 , pp. 28243-28252
    • Guo, P.1    Dong, X.Y.2    Zhao, K.W.3    Sun, X.4    Li, Q.5    Dong, J.T.6
  • 10
    • 0035831436 scopus 로고    scopus 로고
    • Intestinal-enriched kruppel-like factor (kruppel-like factor 5) is a positive regulator of cellular proliferation
    • Sun, R., Chen, X. and Yang, V. W. (2001) Intestinal-enriched kruppel-like factor (kruppel-like factor 5) is a positive regulator of cellular proliferation. J. Biol. Chem. 276, 6897-6900
    • (2001) J. Biol. Chem. , vol.276 , pp. 6897-6900
    • Sun, R.1    Chen, X.2    Yang, V.W.3
  • 11
    • 0034532401 scopus 로고    scopus 로고
    • Positive- And negative-acting Kruppel-like transcription factors bind a transforming growth factor β control element required for expression of the smooth muscle cell differentiation marker SM22α in vivo
    • Adam, P. J., Regan, C. P., Hautmann, M. B. and Owens, G. K. (2000) Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor β control element required for expression of the smooth muscle cell differentiation marker SM22α in vivo. J. Biol. Chem. 275, 37798-37806
    • (2000) J. Biol. Chem. , vol.275 , pp. 37798-37806
    • Adam, P.J.1    Regan, C.P.2    Hautmann, M.B.3    Owens, G.K.4
  • 12
    • 33646435815 scopus 로고    scopus 로고
    • KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells
    • Yang, Y., Goldstein, B. G., Chao, H. H. and Katz, J. P. (2005) KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol. Ther. 4, 1216-1221
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1216-1221
    • Yang, Y.1    Goldstein, B.G.2    Chao, H.H.3    Katz, J.P.4
  • 13
    • 68549104124 scopus 로고    scopus 로고
    • Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases
    • Dong, J. T. and Chen, C. (2009) Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases. Cell. Mol. Life Sci. 66, 2691-2706
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 2691-2706
    • Dong, J.T.1    Chen, C.2
  • 14
    • 65249114297 scopus 로고    scopus 로고
    • Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification
    • Guo, P., Dong, X. Y., Zhang, X., Zhao, K. W., Sun, X., Li, Q. and Dong, J. T. (2009) Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. J. Biol. Chem. 284, 6071-6078
    • (2009) J. Biol. Chem. , vol.284 , pp. 6071-6078
    • Guo, P.1    Dong, X.Y.2    Zhang, X.3    Zhao, K.W.4    Sun, X.5    Li, Q.6    Dong, J.T.7
  • 15
    • 33749423046 scopus 로고    scopus 로고
    • Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis
    • DOI 10.1242/jcs.03070
    • Sur, I., Rozell, B., Jaks, V., Bergstrom, A. and Toftgard, R. (2006) Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis. J. Cell Sci. 119, 3593-3601 (Pubitemid 44501863)
    • (2006) Journal of Cell Science , vol.119 , Issue.17 , pp. 3593-3601
    • Sur, I.1    Rozell, B.2    Jaks, V.3    Bergstrom, A.4    Toftgard, R.5
  • 17
    • 41349110850 scopus 로고    scopus 로고
    • Kruppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection
    • McConnell, B. B., Klapproth, J. M., Sasaki, M., Nandan, M. O. and Yang, V. W. (2008) Kruppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection. Gastroenterology 134, 1007-1016
    • (2008) Gastroenterology , vol.134 , pp. 1007-1016
    • McConnell, B.B.1    Klapproth, J.M.2    Sasaki, M.3    Nandan, M.O.4    Yang, V.W.5
  • 18
    • 34447502510 scopus 로고    scopus 로고
    • Overexpression of Kruppel-like factor 5 in esophageal epithelia in vivo leads to increased proliferation in basal but not suprabasal cells
    • Goldstein, B. G., Chao, H. H., Yang, Y., Yermolina, Y. A., Tobias, J. W. and Katz, J. P. (2007) Overexpression of Kruppel-like factor 5 in esophageal epithelia in vivo leads to increased proliferation in basal but not suprabasal cells. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G1784-G1792
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.292
    • Goldstein, B.G.1    Chao, H.H.2    Yang, Y.3    Yermolina, Y.A.4    Tobias, J.W.5    Katz, J.P.6
  • 19
    • 0037179848 scopus 로고    scopus 로고
    • A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
    • Chen, C., Bhalala, H. V., Qiao, H. and Dong, J. T. (2002) A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 21, 6567-6572
    • (2002) Oncogene , vol.21 , pp. 6567-6572
    • Chen, C.1    Bhalala, H.V.2    Qiao, H.3    Dong, J.T.4
  • 20
    • 0037405689 scopus 로고    scopus 로고
    • KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer
    • Chen, C., Bhalala, H. V., Vessella, R. L. and Dong, J. T. (2003) KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer. Prostate 55, 81-88
    • (2003) Prostate , vol.55 , pp. 81-88
    • Chen, C.1    Bhalala, H.V.2    Vessella, R.L.3    Dong, J.T.4
  • 21
    • 9644277225 scopus 로고    scopus 로고
    • All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5
    • Chanchevalap, S., Nandan, M. O., Merlin, D. and Yang, V. W. (2004) All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5. FEBS Lett. 578, 99-105
    • (2004) FEBS Lett. , vol.578 , pp. 99-105
    • Chanchevalap, S.1    Nandan, M.O.2    Merlin, D.3    Yang, V.W.4
  • 24
    • 33646423520 scopus 로고    scopus 로고
    • Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer
    • Tong, D., Czerwenka, K., Heinze, G., Ryffel, M., Schuster, E., Witt, A., Leodolter, S. and Zeillinger, R. (2006) Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer. Clin. Cancer Res. 12, 2442-2448
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2442-2448
    • Tong, D.1    Czerwenka, K.2    Heinze, G.3    Ryffel, M.4    Schuster, E.5    Witt, A.6    Leodolter, S.7    Zeillinger, R.8
  • 25
    • 73449090855 scopus 로고    scopus 로고
    • Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells
    • Guo, P., Dong, X. Y., Zhao, K. W., Sun, X., Li, Q. and Dong, J. T. (2010) Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells. Int. J. Cancer. 126, 81-89
    • (2010) Int. J. Cancer. , vol.126 , pp. 81-89
    • Guo, P.1    Dong, X.Y.2    Zhao, K.W.3    Sun, X.4    Li, Q.5    Dong, J.T.6
  • 26
    • 0034696939 scopus 로고    scopus 로고
    • Efp as a primary estrogen-responsive gene in human breast cancer
    • DOI 10.1016/S0014-5793(00)01421-6, PII S0014579300014216
    • Ikeda, K., Orimo, A., Higashi, Y., Muramatsu, M. and Inoue, S. (2000) Efp as a primary estrogen-responsive gene in human breast cancer. FEBS Lett. 472, 9-13 (Pubitemid 30224576)
    • (2000) FEBS Letters , vol.472 , Issue.1 , pp. 9-13
    • Ikeda, K.1    Orimo, A.2    Higashi, Y.3    Muramatsu, M.4    Inoue, S.5
  • 27
    • 33645217490 scopus 로고    scopus 로고
    • The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase
    • Zou, W. and Zhang, D. E. (2006) The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase. J. Biol. Chem. 281, 3989-3994
    • (2006) J. Biol. Chem. , vol.281 , pp. 3989-3994
    • Zou, W.1    Zhang, D.E.2
  • 30
    • 33746892585 scopus 로고    scopus 로고
    • Identification and Herc5-mediated ISGylation of novel target proteins
    • Takeuchi, T., Inoue, S. and Yokosawa, H. (2006) Identification and Herc5-mediated ISGylation of novel target proteins. Biochem. Biophys. Res. Commun. 348, 473-477
    • (2006) Biochem. Biophys. Res. Commun. , vol.348 , pp. 473-477
    • Takeuchi, T.1    Inoue, S.2    Yokosawa, H.3
  • 31
    • 33846317359 scopus 로고    scopus 로고
    • Negative regulation of ISG15 E3 ligase EFP through its autoISGylation
    • Zou, W., Wang, J. and Zhang, D. E. (2007) Negative regulation of ISG15 E3 ligase EFP through its autoISGylation. Biochem. Biophys. Res. Commun. 354, 321-327
    • (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 321-327
    • Zou, W.1    Wang, J.2    Zhang, D.E.3
  • 32
    • 33947124663 scopus 로고    scopus 로고
    • Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway
    • Chen, C., Zhou, Z., Guo, P. and Dong, J. T. (2007) Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway. FEBS Lett. 581, 1124-1130
    • (2007) FEBS Lett. , vol.581 , pp. 1124-1130
    • Chen, C.1    Zhou, Z.2    Guo, P.3    Dong, J.T.4
  • 33
    • 18844429239 scopus 로고    scopus 로고
    • Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells
    • Chen, C., Sun, X., Ran, Q., Wilkinson, K. D., Murphy, T. J., Simons, J. W. and Dong, J. T. (2005) Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene 24, 3319-3327
    • (2005) Oncogene , vol.24 , pp. 3319-3327
    • Chen, C.1    Sun, X.2    Ran, Q.3    Wilkinson, K.D.4    Murphy, T.J.5    Simons, J.W.6    Dong, J.T.7
  • 34
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 35
    • 70350575752 scopus 로고    scopus 로고
    • Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1
    • Zheng, H. Q., Zhou, Z., Huang, J., Chaudhury, L., Dong, J. T. and Chen, C. (2009) Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1. Oncogene 28, 3702-3713
    • (2009) Oncogene , vol.28 , pp. 3702-3713
    • Zheng, H.Q.1    Zhou, Z.2    Huang, J.3    Chaudhury, L.4    Dong, J.T.5    Chen, C.6
  • 36
    • 1842839974 scopus 로고    scopus 로고
    • Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells
    • Chen, C., Zhou, Y., Zhou, Z., Sun, X., Otto, K. B., Uht, R. M. and Dong, J. T. (2004) Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells. Gene 330, 133-142
    • (2004) Gene , vol.330 , pp. 133-142
    • Chen, C.1    Zhou, Y.2    Zhou, Z.3    Sun, X.4    Otto, K.B.5    Uht, R.M.6    Dong, J.T.7
  • 37
    • 77953158826 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation
    • Zhao, D., Zheng, H.Q., Zhou, Z. and Chen, C. (2010) The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation. Cancer Res. 70, 4728-4738
    • (2010) Cancer Res. , vol.70 , pp. 4728-4738
    • Zhao, D.1    Zheng, H.Q.2    Zhou, Z.3    Chen, C.4
  • 38
    • 77953310667 scopus 로고    scopus 로고
    • The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs
    • Liu, N., Li, H., Li, S., Shen, M., Xiao, N., Chen, Y., Wang, Y., Wang, W., Wang, R., Wang, Q. et al. (2010) The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J. Biol. Chem. 285, 18858-18867
    • (2010) J. Biol. Chem. , vol.285 , pp. 18858-18867
    • Liu, N.1    Li, H.2    Li, S.3    Shen, M.4    Xiao, N.5    Chen, Y.6    Wang, Y.7    Wang, W.8    Wang, R.9    Wang, Q.10
  • 40
    • 0030016595 scopus 로고    scopus 로고
    • Structure and functions of the 20S and 26S proteasomes
    • Coux, O., Tanaka, K. and Goldberg, A. L. (1996) Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801-847
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 801-847
    • Coux, O.1    Tanaka, K.2    Goldberg, A.L.3
  • 41
    • 11844287006 scopus 로고    scopus 로고
    • Mobilizing the proteolytic machine: Cell biological roles of proteasome activators and inhibitors
    • DOI 10.1016/j.tcb.2004.11.003, PII S0962892404003149
    • Rechsteiner, M. and Hill, C. P. (2005) Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol. 15, 27-33 (Pubitemid 40094678)
    • (2005) Trends in Cell Biology , vol.15 , Issue.1 , pp. 27-33
    • Rechsteiner, M.1    Hill, C.P.2
  • 42
    • 56249108370 scopus 로고    scopus 로고
    • Ubiquitin-independent degradation of proteins by the proteasome
    • Jariel-Encontre, I., Bossis, G. and Piechaczyk, M. (2008) Ubiquitin-independent degradation of proteins by the proteasome. Biochim. Biophys. Acta 1786, 153-177
    • (2008) Biochim. Biophys. Acta , vol.1786 , pp. 153-177
    • Jariel-Encontre, I.1    Bossis, G.2    Piechaczyk, M.3
  • 44
    • 0028875245 scopus 로고
    • Molecular cloning, structure, and expression of mouse estrogen-responsive finger protein Efp. Co-localization with estrogen receptor mRNA in target organs
    • Orimo, A., Inoue, S., Ikeda, K., Noji, S. and Muramatsu, M. (1995) Molecular cloning, structure, and expression of mouse estrogen-responsive finger protein Efp. Co-localization with estrogen receptor mRNA in target organs. J. Biol. Chem. 270, 24406-24413
    • (1995) J. Biol. Chem. , vol.270 , pp. 24406-24413
    • Orimo, A.1    Inoue, S.2    Ikeda, K.3    Noji, S.4    Muramatsu, M.5
  • 46
    • 0030993837 scopus 로고    scopus 로고
    • Uterine preparation for implantation in the mouse is associated with coordinate expression of estrogen-responsive finger protein and estrogen receptor
    • Das, N., Wang, J. and Dey, S. K. (1997) Uterine preparation for implantation in the mouse is associated with coordinate expression of estrogen-responsive finger protein and estrogen receptor. Mol. Reprod. Dev. 46, 499-506
    • (1997) Mol. Reprod. Dev. , vol.46 , pp. 499-506
    • Das, N.1    Wang, J.2    Dey, S.K.3


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