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Volumn 417, Issue 1, 2009, Pages 313-322

KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells

Author keywords

Androgen receptor (AR); Fatty acid synthase (FASN); Kr ppel like factor (KLF) family; Sterol regulatory elementbindingprotein 1 (SREBP 1); Synergism

Indexed keywords

ACETYL-COA CARBOXYLASE; ANDROGEN RECEPTOR (AR); ANDROGEN-DEPENDENT; ATP-CITRATE LYASE; CELLULAR SIGNALLING; ELEMENT-BINDING PROTEINS; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE (FASN); HMG-COA REDUCTASE; KEY REGULATORS; LOW DENSITY LIPOPROTEINS; MRNA LEVEL; ONCOGENESIS; PROMOTER ACTIVITIES; PROMOTER REGION; PROSTATE CANCER CELLS; SMALL INTERFERING RNA; STEROL-REGULATORY-ELEMENTBINDINGPROTEIN-1 (SREBP-1); SYNERGISM; SYNERGISTIC ACTION; SYNTHASE; TRANSCRIPTIONAL REGULATION; ZINC-FINGER TRANSCRIPTION;

EID: 58249088827     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080762     Document Type: Article
Times cited : (32)

References (54)
  • 2
    • 33746623315 scopus 로고    scopus 로고
    • Molecular regulation of androgen action in prostate cancer
    • Dehm, S. M. and Tindall, D. J. (2006) Molecular regulation of androgen action in prostate cancer. J. Cell. Biochem. 99, 333-344
    • (2006) J. Cell. Biochem , vol.99 , pp. 333-344
    • Dehm, S.M.1    Tindall, D.J.2
  • 3
    • 0031007690 scopus 로고    scopus 로고
    • Prostate cancer diagnosis and management
    • Frydenberg, M., Stricker, P. D. and Kaye, K. W. (1997) Prostate cancer diagnosis and management. Lancet 349, 1681-1687
    • (1997) Lancet , vol.349 , pp. 1681-1687
    • Frydenberg, M.1    Stricker, P.D.2    Kaye, K.W.3
  • 4
    • 0029743674 scopus 로고    scopus 로고
    • Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP
    • Swinnen, J. V., Van Veldhoven, P. P., Esquenet, M., Heyns, W. and Verhoeven, G. (1996) Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP. Endocrinology 137, 4468-4474
    • (1996) Endocrinology , vol.137 , pp. 4468-4474
    • Swinnen, J.V.1    Van Veldhoven, P.P.2    Esquenet, M.3    Heyns, W.4    Verhoeven, G.5
  • 5
    • 0030936232 scopus 로고    scopus 로고
    • Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP
    • Swinnen, J. V., Esquenet, M., Goossens, K., Heyns, W. and Verhoeven, G. (1997) Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP. Cancer Res. 57, 1086-1090
    • (1997) Cancer Res , vol.57 , pp. 1086-1090
    • Swinnen, J.V.1    Esquenet, M.2    Goossens, K.3    Heyns, W.4    Verhoeven, G.5
  • 9
    • 0031007392 scopus 로고    scopus 로고
    • Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
    • Gansler, T. S., Hardman, III, W., Hunt, D. A., Schaffel, S. and Hennigar, R. A. (1997) Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum. Pathol. 28, 686-692
    • (1997) Hum. Pathol , vol.28 , pp. 686-692
    • Gansler, T.S.1    Hardman III, W.2    Hunt, D.A.3    Schaffel, S.4    Hennigar, R.A.5
  • 10
    • 0030706079 scopus 로고    scopus 로고
    • Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
    • Milgraum, L. Z., Witters, L. A., Pasternack, G. R. and Kuhajda, F. P. (1997) Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Clin. Cancer Res. 3, 2115-2120
    • (1997) Clin. Cancer Res , vol.3 , pp. 2115-2120
    • Milgraum, L.Z.1    Witters, L.A.2    Pasternack, G.R.3    Kuhajda, F.P.4
  • 12
    • 0033808261 scopus 로고    scopus 로고
    • The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
    • Piyathilake, C. J., Frost, A. R., Manne, U., Bell, W. C., Weiss, H., Heimburger, D. C. and Grizzle, W. E. (2000) The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Hum. Pathol. 31, 1068-1073
    • (2000) Hum. Pathol , vol.31 , pp. 1068-1073
    • Piyathilake, C.J.1    Frost, A.R.2    Manne, U.3    Bell, W.C.4    Weiss, H.5    Heimburger, D.C.6    Grizzle, W.E.7
  • 13
    • 0036151105 scopus 로고    scopus 로고
    • Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach
    • Kusakabe, T., Nashimoto, A., Honma, K. and Suzuki, T. (2002) Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach. Histopathology 40, 71-79
    • (2002) Histopathology , vol.40 , pp. 71-79
    • Kusakabe, T.1    Nashimoto, A.2    Honma, K.3    Suzuki, T.4
  • 16
    • 0034002793 scopus 로고    scopus 로고
    • Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
    • Kuhajda, F. P. (2000) Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 16, 202-208
    • (2000) Nutrition , vol.16 , pp. 202-208
    • Kuhajda, F.P.1
  • 17
    • 0030666828 scopus 로고    scopus 로고
    • Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins
    • Swinnen, J. V., Ulrix, W., Heyns, W. and Verhoeven, G. (1997) Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins. Proc. Natl. Acad. Sci. U.S.A. 94, 12975-12980
    • (1997) Proc. Natl. Acad. Sci. U.S.A , vol.94 , pp. 12975-12980
    • Swinnen, J.V.1    Ulrix, W.2    Heyns, W.3    Verhoeven, G.4
  • 18
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J. D., Goldstein, J. L. and Brown, M. S. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109, 1125-1131
    • (2002) J. Clin. Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 19
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang, T., Espenshade, P. J., Wright, M. E., Yabe, D., Gong, Y., Aebersold, R., Goldstein, J. L. and Brown, M. S. (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110, 489-500
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 20
    • 0030745393 scopus 로고    scopus 로고
    • Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: A critical role for the Btd domain of Sp1
    • Athanikar, J. N., Sanchez, H. B. and Osborne, T. F. (1997) Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: a critical role for the Btd domain of Sp1. Mol. Cell. Biol. 17, 5193-5200
    • (1997) Mol. Cell. Biol , vol.17 , pp. 5193-5200
    • Athanikar, J.N.1    Sanchez, H.B.2    Osborne, T.F.3
  • 21
    • 0037218919 scopus 로고    scopus 로고
    • Sp1- and Kruppel-like transcription factors
    • Kaczynski, J., Cook, T. and Urrutia, R. (2003) Sp1- and Kruppel-like transcription factors. Genome Biol. 4, 206
    • (2003) Genome Biol , vol.4 , pp. 206
    • Kaczynski, J.1    Cook, T.2    Urrutia, R.3
  • 22
    • 0023663884 scopus 로고
    • Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
    • Kadonaga, J. T., Carner, K. R., Masiarz, F. R. and Tjian, R. (1987) Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 51, 1079-1090
    • (1987) Cell , vol.51 , pp. 1079-1090
    • Kadonaga, J.T.1    Carner, K.R.2    Masiarz, F.R.3    Tjian, R.4
  • 23
    • 0036510378 scopus 로고    scopus 로고
    • Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2
    • Song, C. Z., Keller, K., Murata, K., Asano, H. and Stamatoyannopoulos, G. (2002) Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2. J. Biol. Chem. 277, 7029-7036
    • (2002) J. Biol. Chem , vol.277 , pp. 7029-7036
    • Song, C.Z.1    Keller, K.2    Murata, K.3    Asano, H.4    Stamatoyannopoulos, G.5
  • 24
    • 0035099483 scopus 로고    scopus 로고
    • Site-specific acetylation by p300 or CREB binding protein regulates erythroid Kruppel-like factor transcriptional activity via its interaction with the SWI-SNF complex
    • Zhang, W., Kadam, S., Emerson, B. M. and Bieker, J. J. (2001) Site-specific acetylation by p300 or CREB binding protein regulates erythroid Kruppel-like factor transcriptional activity via its interaction with the SWI-SNF complex. Mol. Cell. Biol. 21, 2413-2422
    • (2001) Mol. Cell. Biol , vol.21 , pp. 2413-2422
    • Zhang, W.1    Kadam, S.2    Emerson, B.M.3    Bieker, J.J.4
  • 25
    • 0037106344 scopus 로고    scopus 로고
    • Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter
    • Kaczynski, J. A., Conley, A. A., Fernandez Zapico, M., Delgado, S. M., Zhang, J. S. and Urrutia, R. (2002) Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter. Biochem. J. 366, 873-882
    • (2002) Biochem. J , vol.366 , pp. 873-882
    • Kaczynski, J.A.1    Conley, A.A.2    Fernandez Zapico, M.3    Delgado, S.M.4    Zhang, J.S.5    Urrutia, R.6
  • 26
    • 0031041167 scopus 로고    scopus 로고
    • Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains
    • Majello, B., De Luca, P. and Lania, L. (1997) Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains. J. Biol. Chem. 272, 4021-4026
    • (1997) J. Biol. Chem , vol.272 , pp. 4021-4026
    • Majello, B.1    De Luca, P.2    Lania, L.3
  • 27
    • 0035831436 scopus 로고    scopus 로고
    • Intestinal-enriched Kruppel-like factor (Kruppel-like factor 5) is a positive regulator of cellular proliferation
    • Sun, R., Chen, X. and Yang, V. W. (2001) Intestinal-enriched Kruppel-like factor (Kruppel-like factor 5) is a positive regulator of cellular proliferation. J. Biol. Chem. 276, 6897-6900
    • (2001) J. Biol. Chem , vol.276 , pp. 6897-6900
    • Sun, R.1    Chen, X.2    Yang, V.W.3
  • 28
    • 33644559042 scopus 로고    scopus 로고
    • KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line
    • Chen, C., Benjamin, M. S., Sun, X., Otto, K. B., Guo, P., Dong, X. Y., Bao, Y., Zhou, Z., Cheng, X., Simons, J. W. and Dong, J. T. (2006) KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line. Int. J. Cancer 118, 1346-1355
    • (2006) Int. J. Cancer , vol.118 , pp. 1346-1355
    • Chen, C.1    Benjamin, M.S.2    Sun, X.3    Otto, K.B.4    Guo, P.5    Dong, X.Y.6    Bao, Y.7    Zhou, Z.8    Cheng, X.9    Simons, J.W.10    Dong, J.T.11
  • 29
    • 66849132951 scopus 로고    scopus 로고
    • Leake, R. E., Freshney, R. I. and Munir, I. (1987) Steroid response in vivo and in vitro. In Steroid Hormones: a Practical Approach (Green, B. and Leake, R. E., eds.), p. 214, IRL Press, Washington D.C.
    • Leake, R. E., Freshney, R. I. and Munir, I. (1987) Steroid response in vivo and in vitro. In Steroid Hormones: a Practical Approach (Green, B. and Leake, R. E., eds.), p. 214, IRL Press, Washington D.C.
  • 30
    • 66849096285 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted
  • 31
    • 12644314084 scopus 로고    scopus 로고
    • Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter
    • Magana, M. M. and Osborne, T. F. (1996) Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. J. Biol. Chem. 271, 32689-32694
    • (1996) J. Biol. Chem , vol.271 , pp. 32689-32694
    • Magana, M.M.1    Osborne, T.F.2
  • 32
    • 0031801013 scopus 로고    scopus 로고
    • Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase
    • Inoue, J., Sato, R. and Maeda, M. (1998) Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase. J. Biochem. (Tokyo) 123, 1191-1198
    • (1998) J. Biochem. (Tokyo) , vol.123 , pp. 1191-1198
    • Inoue, J.1    Sato, R.2    Maeda, M.3
  • 33
    • 0028799622 scopus 로고
    • Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene
    • Sanchez, H. B., Yieh, L. and Osborne, T. F. (1995) Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene. J. Biol. Chem. 270, 1161-1169
    • (1995) J. Biol. Chem , vol.270 , pp. 1161-1169
    • Sanchez, H.B.1    Yieh, L.2    Osborne, T.F.3
  • 34
    • 0043210499 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase β gene is regulated by sterol regulatory element-binding protein-1 in liver
    • Oh, S. Y., Park, S. K., Kim, J. W., Ahn, Y. H., Park, S. W. and Kim, K. S. (2003) Acetyl-CoA carboxylase β gene is regulated by sterol regulatory element-binding protein-1 in liver. J. Biol. Chem. 278, 28410-28417
    • (2003) J. Biol. Chem , vol.278 , pp. 28410-28417
    • Oh, S.Y.1    Park, S.K.2    Kim, J.W.3    Ahn, Y.H.4    Park, S.W.5    Kim, K.S.6
  • 35
    • 0031892148 scopus 로고    scopus 로고
    • Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y
    • Dooley, K. A., Millinder, S. and Osborne, T. F. (1998) Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y. J. Biol. Chem. 273, 1349-1356
    • (1998) J. Biol. Chem , vol.273 , pp. 1349-1356
    • Dooley, K.A.1    Millinder, S.2    Osborne, T.F.3
  • 36
    • 0034730504 scopus 로고    scopus 로고
    • The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter
    • Moon, Y. A., Lee, J. J., Park, S. W., Ahn, Y. H. and Kim, K. S. (2000) The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter. J. Biol. Chem. 275, 30280-30286
    • (2000) J. Biol. Chem , vol.275 , pp. 30280-30286
    • Moon, Y.A.1    Lee, J.J.2    Park, S.W.3    Ahn, Y.H.4    Kim, K.S.5
  • 37
    • 33744955883 scopus 로고    scopus 로고
    • KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia
    • Zhu, N., Gu, L., Findley, H. W., Chen, C., Dong, J. T., Yang, L. and Zhou, M. (2006) KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia. J. Biol. Chem. 281, 14711-14718
    • (2006) J. Biol. Chem , vol.281 , pp. 14711-14718
    • Zhu, N.1    Gu, L.2    Findley, H.W.3    Chen, C.4    Dong, J.T.5    Yang, L.6    Zhou, M.7
  • 38
    • 0036639383 scopus 로고    scopus 로고
    • Opposing effects of Kruppel-like factor 4 (gut-enriched Kruppel-like factor) and Kruppel-like factor 5 (intestinal-enriched Kruppel-like factor) on the promoter of the Kruppel-like factor 4 gene
    • Dang, D. T., Zhao, W., Mahatan, C. S., Geiman, D. E. and Yang, V. W. (2002) Opposing effects of Kruppel-like factor 4 (gut-enriched Kruppel-like factor) and Kruppel-like factor 5 (intestinal-enriched Kruppel-like factor) on the promoter of the Kruppel-like factor 4 gene. Nucleic Acids Res. 30, 2736-2741
    • (2002) Nucleic Acids Res , vol.30 , pp. 2736-2741
    • Dang, D.T.1    Zhao, W.2    Mahatan, C.S.3    Geiman, D.E.4    Yang, V.W.5
  • 39
    • 27544446292 scopus 로고    scopus 로고
    • 12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells
    • 12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells. Mol. Pharmacol. 68, 1203-1213
    • (2005) Mol. Pharmacol , vol.68 , pp. 1203-1213
    • Chen, Z.Y.1    Tseng, C.C.2
  • 42
    • 0034791515 scopus 로고    scopus 로고
    • Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway
    • Heemers, H., Maes, B., Foufelle, F., Heyns, W., Verhoeven, G. and Swinnen, J. V. (2001) Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway. Mol. Endocrinol. 15, 1817-1828
    • (2001) Mol. Endocrinol , vol.15 , pp. 1817-1828
    • Heemers, H.1    Maes, B.2    Foufelle, F.3    Heyns, W.4    Verhoeven, G.5    Swinnen, J.V.6
  • 43
    • 34548814981 scopus 로고    scopus 로고
    • Up-regulation of acetyl-CoA carboxylase α and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
    • Yoon, S., Lee, M. Y., Park, S. W., Moon, J. S., Koh, Y. K., Ahn, Y. H., Park, B. W. and Kim, K. S. (2007) Up-regulation of acetyl-CoA carboxylase α and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. J. Biol. Chem. 282, 26122-26131
    • (2007) J. Biol. Chem , vol.282 , pp. 26122-26131
    • Yoon, S.1    Lee, M.Y.2    Park, S.W.3    Moon, J.S.4    Koh, Y.K.5    Ahn, Y.H.6    Park, B.W.7    Kim, K.S.8
  • 44
    • 0035860820 scopus 로고    scopus 로고
    • Kruppel-like factors: Three fingers in many pies
    • Bieker, J. J. (2001) Kruppel-like factors: three fingers in many pies. J. Biol. Chem. 276, 34355-34358
    • (2001) J. Biol. Chem , vol.276 , pp. 34355-34358
    • Bieker, J.J.1
  • 45
    • 0034532675 scopus 로고    scopus 로고
    • The biology of the mammalian Kruppel-like family of transcription factors
    • Dang, D. T., Pevsner, J. and Yang, V. W. (2000) The biology of the mammalian Kruppel-like family of transcription factors. Int. J. Biochem. Cell Biol. 32, 1103-1121
    • (2000) Int. J. Biochem. Cell Biol , vol.32 , pp. 1103-1121
    • Dang, D.T.1    Pevsner, J.2    Yang, V.W.3
  • 47
    • 0035839554 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen, X., Johns, D. C., Geiman, D. E., Marban, E., Dang, D. T., Hamlin, G., Sun, R. and Yang, V. W. (2001) Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 276, 30423-30428
    • (2001) J. Biol. Chem , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3    Marban, E.4    Dang, D.T.5    Hamlin, G.6    Sun, R.7    Yang, V.W.8
  • 48
    • 2442686555 scopus 로고    scopus 로고
    • Kruppel-like factor 5 mediates the transforming activity of oncogenic H-Ras
    • Nandan, M. O., Yoon, H. S., Zhao, W., Ouko, L. A., Chanchevalap, S. and Yang, V. W. (2004) Kruppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. Oncogene 23, 3404-3413
    • (2004) Oncogene , vol.23 , pp. 3404-3413
    • Nandan, M.O.1    Yoon, H.S.2    Zhao, W.3    Ouko, L.A.4    Chanchevalap, S.5    Yang, V.W.6
  • 50
    • 34250216304 scopus 로고    scopus 로고
    • The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology
    • McConnell, B. B., Ghaleb, A. M., Nandan, M. O. and Yang, V. W. (2007) The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology. BioEssays 29, 549-557
    • (2007) BioEssays , vol.29 , pp. 549-557
    • McConnell, B.B.1    Ghaleb, A.M.2    Nandan, M.O.3    Yang, V.W.4
  • 51
    • 0034532401 scopus 로고    scopus 로고
    • Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor β control element required for expression of the smooth muscle cell differentiation marker SM22α in vivo
    • Adam, P. J., Regan, C. P., Hautmann, M. B. and Owens, G. K. (2000) Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor β control element required for expression of the smooth muscle cell differentiation marker SM22α in vivo. J. Biol. Chem. 275, 37798-37806
    • (2000) J. Biol. Chem , vol.275 , pp. 37798-37806
    • Adam, P.J.1    Regan, C.P.2    Hautmann, M.B.3    Owens, G.K.4
  • 52
    • 0032503693 scopus 로고    scopus 로고
    • The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion
    • Zhang, W., Shields, J. M., Sogawa, K., Fujii-Kuriyama, Y. and Yang, V. W. (1998) The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. J. Biol. Chem. 273, 17917-17925
    • (1998) J. Biol. Chem , vol.273 , pp. 17917-17925
    • Zhang, W.1    Shields, J.M.2    Sogawa, K.3    Fujii-Kuriyama, Y.4    Yang, V.W.5
  • 53
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest
    • Shields, J. M., Christy, R. J. and Yang, V. W. (1996) Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest. J. Biol. Chem. 271, 20009-20017
    • (1996) J. Biol. Chem , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 54
    • 0033104158 scopus 로고    scopus 로고
    • A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells
    • Conkright, M. D., Wani, M. A., Anderson, K. P. and Lingrel, J. B. (1999) A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells. Nucleic Acids Res. 27, 1263-1270
    • (1999) Nucleic Acids Res , vol.27 , pp. 1263-1270
    • Conkright, M.D.1    Wani, M.A.2    Anderson, K.P.3    Lingrel, J.B.4


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