메뉴 건너뛰기




Volumn 25, Issue 7, 2011, Pages 1137-1144

The induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and dedifferentiation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYTOKERATIN 5; ESTROGEN; KRUPPEL LIKE FACTOR 5; MESSENGER RNA; PROGESTERONE; REPLICATION LICENSING FACTOR CDT1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR E2F3;

EID: 79959832245     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0497     Document Type: Article
Times cited : (51)

References (44)
  • 2
    • 0346996801 scopus 로고    scopus 로고
    • Progesterone involvement in breast development and tumorigenesis-as revealed by progesterone receptor "knockout" and "knockin" mouse models
    • Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW, Lydon JP 2003 Progesterone involvement in breast development and tumorigenesis-as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids 68:779-787
    • (2003) Steroids , vol.68 , pp. 779-787
    • Ismail, P.M.1    Amato, P.2    Soyal, S.M.3    Demayo, F.J.4    Conneely, O.M.5    O'Malley, B.W.6    Lydon, J.P.7
  • 3
    • 44549088535 scopus 로고    scopus 로고
    • Challenges to defining a role for progesterone in breast cancer
    • Lange CA 2008 Challenges to defining a role for progesterone in breast cancer. Steroids 73:914-921
    • (2008) Steroids , vol.73 , pp. 914-921
    • Lange, C.A.1
  • 5
  • 6
    • 0036339068 scopus 로고    scopus 로고
    • Estrogen and estrogen-progestin replacement therapy and risk of postmenopausal breast cancer in Canada
    • Kirsh V, Kreiger N 2002 Estrogen and estrogen-progestin replacement therapy and risk of postmenopausal breast cancer in Canada. Cancer Causes Control 13:583-590
    • (2002) Cancer Causes Control , vol.13 , pp. 583-590
    • Kirsh, V.1    Kreiger, N.2
  • 7
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women Study
    • Beral V 2003 Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 362:419-427
    • (2003) Lancet , vol.362 , pp. 419-427
    • Beral, V.1
  • 8
    • 0023212905 scopus 로고
    • Progestin effects on growth in the human breast cancer cell line T-47D-possible therapeutic implications
    • Hissom JR, Moore MR 1987 Progestin effects on growth in the human breast cancer cell line T-47D-possible therapeutic implications. Biochem Biophys Res Commun 145:706-711
    • (1987) Biochem Biophys Res Commun , vol.145 , pp. 706-711
    • Hissom, J.R.1    Moore, M.R.2
  • 9
    • 35448981411 scopus 로고    scopus 로고
    • Progestin- dependent progression of human breast tumor xenografts: A novel model for evaluating antitumor therapeutics
    • Liang Y, Besch-Williford C, Brekken RA, Hyder SM 2007 Progestin- dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics. Cancer Res 67: 9929-9936
    • (2007) Cancer Res , vol.67 , pp. 9929-9936
    • Liang, Y.1    Besch-Williford, C.2    Brekken, R.A.3    Hyder, S.M.4
  • 10
    • 0014099063 scopus 로고
    • Effects of progesterone on 9,10-dimethyl-1,2- benzanthracene-induced mammary tumours in Sprague-Dawley rats
    • Jabara AG 1967 Effects of progesterone on 9,10-dimethyl-1,2- benzanthracene-induced mammary tumours in Sprague-Dawley rats. Br J Cancer 21:418-429
    • (1967) Br J Cancer , vol.21 , pp. 418-429
    • Jabara, A.G.1
  • 11
    • 33746076355 scopus 로고    scopus 로고
    • Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats
    • Benakanakere I, Besch-Williford C, Schnell J, Brandt S, Ellersieck MR, Molinolo A, Hyder SM 2006 Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats. Clin Cancer Res 12:4062-4071
    • (2006) Clin Cancer Res , vol.12 , pp. 4062-4071
    • Benakanakere, I.1    Besch-Williford, C.2    Schnell, J.3    Brandt, S.4    Ellersieck, M.R.5    Molinolo, A.6    Hyder, S.M.7
  • 12
    • 42149169048 scopus 로고    scopus 로고
    • Both ovarian hormones estrogen and progesterone are neces-sary for hormonal mammary carcinogenesis in ovariectomized ACI rats
    • Blank EW, Wong PY, Lakshmanaswamy R, Guzman R, Nandi S 2008 Both ovarian hormones estrogen and progesterone are neces-sary for hormonal mammary carcinogenesis in ovariectomized ACI rats. Proc Natl Acad Sci USA 105:3527-3532
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3527-3532
    • Blank, E.W.1    Wong, P.Y.2    Lakshmanaswamy, R.3    Guzman, R.4    Nandi, S.5
  • 13
    • 0019816169 scopus 로고
    • Gross and histopathologic effects of medroxyprogesterone acetate and progesterone on the mammary glands of adult beagle bitches
    • Concannon PW, Spraker TR, Casey HW, Hansel W 1981 Gross and histopathologic effects of medroxyprogesterone acetate and progesterone on the mammary glands of adult beagle bitches. Fertil Steril 36:373-387
    • (1981) Fertil Steril , vol.36 , pp. 373-387
    • Concannon, P.W.1    Spraker, T.R.2    Casey, H.W.3    Hansel, W.4
  • 14
    • 27544495512 scopus 로고    scopus 로고
    • Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth
    • Sartorius CA, Harvell DM, Shen T, Horwitz KB 2005 Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth. Cancer Res 65: 9779-9788
    • (2005) Cancer Res , vol.65 , pp. 9779-9788
    • Sartorius, C.A.1    Harvell, D.M.2    Shen, T.3    Horwitz, K.B.4
  • 15
    • 44449142900 scopus 로고    scopus 로고
    • Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts
    • Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA 2008 Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci USA 105:5774-5779
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5774-5779
    • Horwitz, K.B.1    Dye, W.W.2    Harrell, J.C.3    Kabos, P.4    Sartorius, C.A.5
  • 16
    • 79959213451 scopus 로고    scopus 로고
    • Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers
    • 28 July, 1007/ s10549-010-1078-6
    • Kabos P, Haughian JM, Wang X, Dye WW, Finlayson C, Elias A, Horwitz KB, Sartorius CA 28 July 2010 Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers. Breast Cancer Res Treat 10.1007/ s10549-010-1078-6
    • (2010) Breast Cancer Res Treat , vol.10
    • Kabos, P.1    Haughian, J.M.2    Wang, X.3    Dye, W.W.4    Finlayson, C.5    Elias, A.6    Horwitz, K.B.7    Sartorius, C.A.8
  • 17
    • 79959820178 scopus 로고    scopus 로고
    • Role of progesterone in the etiology of breast cancer in an animal model
    • Shanghai, China
    • Haslam S Role of progesterone in the etiology of breast cancer in an animal model. BIT's 3rd World Cancer Congress: Breast Cancer Conference, Shanghai, China, 2010, p. 146.
    • (2010) BIT's 3rd World Cancer Congress: Breast Cancer Conference , pp. 146
    • Haslam, S.1
  • 19
    • 70350575752 scopus 로고    scopus 로고
    • Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1
    • Zheng HQ, Zhou Z, Huang J, Chaudhury L, Dong JT, Chen C 2009 Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1. Oncogene 28:3702-3713
    • (2009) Oncogene , vol.28 , pp. 3702-3713
    • Zheng, H.Q.1    Zhou, Z.2    Huang, J.3    Chaudhury, L.4    Dong, J.T.5    Chen, C.6
  • 20
    • 67650522872 scopus 로고    scopus 로고
    • KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization
    • Liu R, Zheng HQ, Zhou Z, Dong JT, Chen C 2009 KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. J Biol Chem 284:16791-16798
    • (2009) J Biol Chem , vol.284 , pp. 16791-16798
    • Liu, R.1    Zheng, H.Q.2    Zhou, Z.3    Dong, J.T.4    Chen, C.5
  • 25
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA 2008 An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40:499-507
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 26
    • 33646423520 scopus 로고    scopus 로고
    • Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer
    • Tong D, Czerwenka K, Heinze G, Ryffel M, Schuster E, Witt A, Leodolter S, Zeillinger R 2006 Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer. Clin Cancer Res 12:2442-2448
    • (2006) Clin Cancer Res , vol.12 , pp. 2442-2448
    • Tong, D.1    Czerwenka, K.2    Heinze, G.3    Ryffel, M.4    Schuster, E.5    Witt, A.6    Leodolter, S.7    Zeillinger, R.8
  • 27
    • 1842839974 scopus 로고    scopus 로고
    • Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells
    • Chen C, Zhou Y, Zhou Z, Sun X, Otto KB, Uht RM, Dong JT 2004 Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells. Gene 330:133-142
    • (2004) Gene , vol.330 , pp. 133-142
    • Chen, C.1    Zhou, Y.2    Zhou, Z.3    Sun, X.4    Otto, K.B.5    Uht, R.M.6    Dong, J.T.7
  • 30
    • 33846581488 scopus 로고    scopus 로고
    • The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle
    • Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP 2007 The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol 21:359-375
    • (2007) Mol Endocrinol , vol.21 , pp. 359-375
    • Boonyaratanakornkit, V.1    McGowan, E.2    Sherman, L.3    Mancini, M.A.4    Cheskis, B.J.5    Edwards, D.P.6
  • 31
    • 77953158826 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation
    • Zhao D, Zheng HQ, Zhou Z, Chen C 2010 The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation. Cancer Res 70:4728-4738
    • (2010) Cancer Res , vol.70 , pp. 4728-4738
    • Zhao, D.1    Zheng, H.Q.2    Zhou, Z.3    Chen, C.4
  • 32
    • 0030806943 scopus 로고    scopus 로고
    • Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo
    • Said TK, Conneely OM, Medina D, O'Malley BW, Lydon JP 1997 Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology 138: 3933-3939
    • (1997) Endocrinology , vol.138 , pp. 3933-3939
    • Said, T.K.1    Conneely, O.M.2    Medina, D.3    O'Malley, B.W.4    Lydon, J.P.5
  • 33
    • 1842425769 scopus 로고    scopus 로고
    • Intestinal tumor progression is associated with altered function of KLF5
    • Bateman NW, Tan D, Pestell RG, Black JD, Black AR 2004 Intestinal tumor progression is associated with altered function of KLF5. J Biol Chem 279:12093-12101
    • (2004) J Biol Chem , vol.279 , pp. 12093-12101
    • Bateman, N.W.1    Tan, D.2    Pestell, R.G.3    Black, J.D.4    Black, A.R.5
  • 35
    • 73449090855 scopus 로고    scopus 로고
    • Estrogeninduced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells
    • Guo P, Dong XY, Zhao KW, Sun X, Li Q, Dong JT 2010 Estrogeninduced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells. Int J Cancer 126:81-89
    • (2010) Int J Cancer , vol.126 , pp. 81-89
    • Guo, P.1    Dong, X.Y.2    Zhao, K.W.3    Sun, X.4    Li, Q.5    Dong, J.T.6
  • 36
    • 0035831436 scopus 로고    scopus 로고
    • Intestinal-enriched Kruppel-like factor (Kruppel-like factor 5) is a positive regulator of cellular proliferation
    • Sun R, Chen X, Yang VW 2001 Intestinal-enriched Kruppel-like factor (Kruppel-like factor 5) is a positive regulator of cellular proliferation. J Biol Chem 276:6897-6900
    • (2001) J Biol Chem , vol.276 , pp. 6897-6900
    • Sun, R.1    Chen, X.2    Yang, V.W.3
  • 38
    • 0035164288 scopus 로고    scopus 로고
    • Identification of a mouse homolog of the human BTEB2 transcription factor as a β-cateninindependent Wnt-1-responsive gene
    • Ziemer LT, Pennica D, Levine AJ 2001 Identification of a mouse homolog of the human BTEB2 transcription factor as a β-cateninindependent Wnt-1-responsive gene. Mol Cell Biol 21:562-574
    • (2001) Mol Cell Biol , vol.21 , pp. 562-574
    • Ziemer, L.T.1    Pennica, D.2    Levine, A.J.3
  • 39
  • 40
    • 58249088827 scopus 로고    scopus 로고
    • KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells
    • Lee MY, Moon JS, Park SW, Koh YK, Ahn YH, Kim KS 2009 KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells. Biochem J 417:313-322
    • (2009) Biochem J , vol.417 , pp. 313-322
    • Lee, M.Y.1    Moon, J.S.2    Park, S.W.3    Koh, Y.K.4    Ahn, Y.H.5    Kim, K.S.6
  • 41
    • 23044500236 scopus 로고    scopus 로고
    • Progesterone receptor isoforms A and B: Temporal and spatial differences in expression during murine mammary gland development
    • Aupperlee MD, Smith KT, Kariagina A, Haslam SZ 2005 Progesterone receptor isoforms A and B: temporal and spatial differences in expression during murine mammary gland development. Endocrinology 146:3577-3588
    • (2005) Endocrinology , vol.146 , pp. 3577-3588
    • Aupperlee, M.D.1    Smith, K.T.2    Kariagina, A.3    Haslam, S.Z.4
  • 44
    • 18844429239 scopus 로고    scopus 로고
    • Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells
    • Chen C, Sun X, Ran Q, Wilkinson KD, Murphy TJ, Simons JW, Dong JT 2005 Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene 24:3319-3327
    • (2005) Oncogene , vol.24 , pp. 3319-3327
    • Chen, C.1    Sun, X.2    Ran, Q.3    Wilkinson, K.D.4    Murphy, T.J.5    Simons, J.W.6    Dong, J.T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.