메뉴 건너뛰기




Volumn 77, Issue 1, 2014, Pages 5-20

Neuropeptide receptors as potential drug targets in the treatment of inflammatory conditions

Author keywords

calcitonin gene related peptide; cortistatin; galanin; pituitary adenylate cyclase activating polypeptide; somatostatin; tachykinin

Indexed keywords

17ALPHA ETHYNYL 17BETA HYDROXY 5ALPHA ANDROSTANO[3,2 B]PYRIMIDO[1,2 A]BENZIMIDAZOLE; 2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; 2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; 2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 3 (2 METHOXY 5 TRIFLUOROMETHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; 5 [[2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 MORPHOLINYL]METHYL] N,N DIMETHYL 1H 1,2,3 TRIAZOLE 4 METHANAMINE; ADRENOMEDULLIN; APREPITANT; CORTISTATIN; CYTOKINE; DEXAMETHASONE; GALANIN; GHRELIN; HORMONE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INTERMEDIN; N BENZYL N2 [4 HYDROXY 1 [(1 METHYL 1H INDOL 3 YL)CARBONYL]PROLYL] N METHYL 3 (2 NAPHTHYL)ALANINAMIDE; NEUROPEPTIDE; NEUROPEPTIDE RECEPTOR; NOLPITANTIUM; OPIATE PEPTIDE; PHYSALAEMIN[9 DEXTRO PROLINE SPIRO GAMMA LACTAM 10 LEUCINE 11 TRYPTOPHAN]; ROLAPITANT; SOMATOSTATIN; TACHYKININ; TACHYKININ RECEPTOR; UNINDEXED DRUG; UROCORTIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VOFOPITANT; ANTIINFLAMMATORY AGENT; AUTACOID;

EID: 84891106934     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12097     Document Type: Article
Times cited : (60)

References (173)
  • 1
    • 0028816358 scopus 로고
    • Tachykinins and calcitonin gene-related peptide (CGRP) as cotransmitters released from peripheral endings of sensory nerves
    • Maggi CA,. Tachykinins and calcitonin gene-related peptide (CGRP) as cotransmitters released from peripheral endings of sensory nerves. Prog Neurobiol 1995; 45: 1-98.
    • (1995) Prog Neurobiol , vol.45 , pp. 1-98
    • Maggi, C.A.1
  • 2
    • 0020682887 scopus 로고
    • Substance P - A putative mediator of antidromic vasodilation
    • Pernow B,. Substance P-a putative mediator of antidromic vasodilation. Gen Pharmacol 1983; 14: 13-16.
    • (1983) Gen Pharmacol , vol.14 , pp. 13-16
    • Pernow, B.1
  • 3
    • 0030722614 scopus 로고    scopus 로고
    • Neurokinin-receptor antagonists: Pharmacological tools and therapeutic drugs
    • Longmore J, Hill RG, Hargreaves RJ,. Neurokinin-receptor antagonists: pharmacological tools and therapeutic drugs. Can J Physiol Pharmacol 1997; 75: 612-621.
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 612-621
    • Longmore, J.1    Hill, R.G.2    Hargreaves, R.J.3
  • 6
    • 0033622173 scopus 로고    scopus 로고
    • NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats
    • Zaratin P, Angelici O, Clarke GD, Schmid G, Raiteri M, Carità F, Bonanno G,. NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats. Neuropharmacology 2000; 39: 141-149.
    • (2000) Neuropharmacology , vol.39 , pp. 141-149
    • Zaratin, P.1    Angelici, O.2    Clarke, G.D.3    Schmid, G.4    Raiteri, M.5    Carità, F.6    Bonanno, G.7
  • 8
    • 33750977552 scopus 로고    scopus 로고
    • Defensive and pathological functions of the gastrointestinal NK3 receptor
    • Sanger GJ, Tuladhar BR, Bueno L, Furness JB,. Defensive and pathological functions of the gastrointestinal NK3 receptor. Vascul Pharmacol 2006; 45: 215-220.
    • (2006) Vascul Pharmacol , vol.45 , pp. 215-220
    • Sanger, G.J.1    Tuladhar, B.R.2    Bueno, L.3    Furness, J.B.4
  • 9
    • 0034332431 scopus 로고    scopus 로고
    • Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis
    • Zhang Y, Lu L, Furlonger C, Wu GE, Paige CJ,. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol 2000; 1: 392-397.
    • (2000) Nat Immunol , vol.1 , pp. 392-397
    • Zhang, Y.1    Lu, L.2    Furlonger, C.3    Wu, G.E.4    Paige, C.J.5
  • 11
    • 2442680385 scopus 로고    scopus 로고
    • Cutting edge: Hemokinin has substance P-like function and expression in inflammation
    • Metwali A, Blum AM, Elliott DE, Setiawan T, Weinstock JV,. Cutting edge: hemokinin has substance P-like function and expression in inflammation. J Immunol 2004; 172: 6528-6532.
    • (2004) J Immunol , vol.172 , pp. 6528-6532
    • Metwali, A.1    Blum, A.M.2    Elliott, D.E.3    Setiawan, T.4    Weinstock, J.V.5
  • 12
    • 4444337231 scopus 로고    scopus 로고
    • Non-neuronal mammalian tachykinin expression
    • Nelson DA, Bost KL,. Non-neuronal mammalian tachykinin expression. Front Biosci 2004; 9: 2166-2176.
    • (2004) Front Biosci , vol.9 , pp. 2166-2176
    • Nelson, D.A.1    Bost, K.L.2
  • 13
    • 84862775248 scopus 로고    scopus 로고
    • Hemokinins modulate endothelium function and promote angiogenesis through neurokinin-1 receptor
    • Song H, Yin W, Zeng Q, Jia H, Lin L, Liu X, Mu L, Wang R,. Hemokinins modulate endothelium function and promote angiogenesis through neurokinin-1 receptor. Int J Biochem Cell Biol 2012; 44: 1410-1421.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1410-1421
    • Song, H.1    Yin, W.2    Zeng, Q.3    Jia, H.4    Lin, L.5    Liu, X.6    Mu, L.7    Wang, R.8
  • 14
    • 77955657706 scopus 로고    scopus 로고
    • Subcutaneous injection of endokinin C/D attenuates carrageenan-induced inflammation
    • Naono-Nakayama R, Sunakawa N, Ikeda T, Matsushima O, Nishimori T,. Subcutaneous injection of endokinin C/D attenuates carrageenan-induced inflammation. Peptides 2010; 31: 1767-1771.
    • (2010) Peptides , vol.31 , pp. 1767-1771
    • Naono-Nakayama, R.1    Sunakawa, N.2    Ikeda, T.3    Matsushima, O.4    Nishimori, T.5
  • 15
    • 20444495565 scopus 로고    scopus 로고
    • Hemokinin-1 has substance P-like function in U-251 MG astrocytoma cells: A pharmacological and functional study
    • Berger A, Paige CJ,. Hemokinin-1 has substance P-like function in U-251 MG astrocytoma cells: a pharmacological and functional study. J Neuroimmunol 2005; 164: 48-56.
    • (2005) J Neuroimmunol , vol.164 , pp. 48-56
    • Berger, A.1    Paige, C.J.2
  • 17
    • 3242711140 scopus 로고    scopus 로고
    • Hemokinins and endokinins
    • Page NM,. Hemokinins and endokinins. Cell Mol Life Sci 2004; 61: 1652-1663.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 1652-1663
    • Page, N.M.1
  • 18
    • 33751041140 scopus 로고    scopus 로고
    • Characterization of the gene structures, precursor processing and pharmacology of the endokinin peptides
    • Page NM,. Characterization of the gene structures, precursor processing and pharmacology of the endokinin peptides. Vascul Pharmacol 2006; 45: 200-208.
    • (2006) Vascul Pharmacol , vol.45 , pp. 200-208
    • Page, N.M.1
  • 19
    • 28744438238 scopus 로고    scopus 로고
    • Effect of intrathecal administration of hemokinin-1 on the withdrawal response to noxious thermal stimulation of the rat hind paw
    • Endo D, Ikeda T, Ishida Y, Yoshioka D, Nishimori T,. Effect of intrathecal administration of hemokinin-1 on the withdrawal response to noxious thermal stimulation of the rat hind paw. Neurosci Lett 2006; 392: 114-117.
    • (2006) Neurosci Lett , vol.392 , pp. 114-117
    • Endo, D.1    Ikeda, T.2    Ishida, Y.3    Yoshioka, D.4    Nishimori, T.5
  • 23
    • 33847374339 scopus 로고    scopus 로고
    • Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation
    • Landau AM, Yashpal K, Cahill CM, St Louis M, Ribeiro-da-Silva A, Henry JL,. Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation. Neuroscience 2007; 145: 699-707.
    • (2007) Neuroscience , vol.145 , pp. 699-707
    • Landau, A.M.1    Yashpal, K.2    Cahill, C.M.3    St Louis, M.4    Ribeiro-Da-Silva, A.5    Henry, J.L.6
  • 24
    • 33748961801 scopus 로고    scopus 로고
    • Suppression of autoimmune encephalomyelitis by a neurokinin-1 receptor antagonist - A putative role for substance P in CNS inflammation
    • Nessler S, Stadelmann C, Bittner A, Schlegel K, Gronen F, Brueck W, Hemmer B, Sommer N,. Suppression of autoimmune encephalomyelitis by a neurokinin-1 receptor antagonist-a putative role for substance P in CNS inflammation. J Neuroimmunol 2006; 179: 1-8.
    • (2006) J Neuroimmunol , vol.179 , pp. 1-8
    • Nessler, S.1    Stadelmann, C.2    Bittner, A.3    Schlegel, K.4    Gronen, F.5    Brueck, W.6    Hemmer, B.7    Sommer, N.8
  • 25
    • 84859639678 scopus 로고    scopus 로고
    • Involvement of tachykinins and NK1 receptor in the joint inflammation with collagen type II-specific monoclonal antibody-induced arthritis in mice
    • Makino A, Sakai A, Ito H, Suzuki H,. Involvement of tachykinins and NK1 receptor in the joint inflammation with collagen type II-specific monoclonal antibody-induced arthritis in mice. J Nippon Med Sch 2012; 79: 129-138.
    • (2012) J Nippon Med Sch , vol.79 , pp. 129-138
    • Makino, A.1    Sakai, A.2    Ito, H.3    Suzuki, H.4
  • 26
    • 80052052663 scopus 로고    scopus 로고
    • Intra-articular administration of tachykinin NK1 receptor antagonists reduces hyperalgesia and cartilage destruction in the inflammatory joint in rats with adjuvant-induced arthritis
    • Uematsu T, Sakai A, Ito H, Suzuki H,. Intra-articular administration of tachykinin NK1 receptor antagonists reduces hyperalgesia and cartilage destruction in the inflammatory joint in rats with adjuvant-induced arthritis. Eur J Pharmacol 2011; 668: 163-168.
    • (2011) Eur J Pharmacol , vol.668 , pp. 163-168
    • Uematsu, T.1    Sakai, A.2    Ito, H.3    Suzuki, H.4
  • 27
    • 0036011199 scopus 로고    scopus 로고
    • 1)-Rezeptorantagonisten in der Schmerztherapie?
    • 1)- Rezeptorantagonisten in der Schmerztherapie? Anaesthesist 2002; 51: 308-319.
    • (2002) Anaesthesist , vol.51 , pp. 308-319
    • Herbert, M.K.1    Holzer, P.2
  • 28
    • 0031568237 scopus 로고    scopus 로고
    • The activity of GR205171, a potent non-peptide tachykinin NK1 receptor antagonist, in the trigeminovascular system
    • Polley JS, Gaskin PJ, Perren MJ, Connor HE, Ward P, Beattie DT,. The activity of GR205171, a potent non-peptide tachykinin NK1 receptor antagonist, in the trigeminovascular system. Regul Pept 1997; 68: 23-29.
    • (1997) Regul Pept , vol.68 , pp. 23-29
    • Polley, J.S.1    Gaskin, P.J.2    Perren, M.J.3    Connor, H.E.4    Ward, P.5    Beattie, D.T.6
  • 29
    • 0037192420 scopus 로고    scopus 로고
    • Local neurokinin-1 receptor in the knee joint contributes to the induction, but not maintenance, of arthritic pain in the rat
    • Hong SK, Han JS, Min SS, Hwang JM, Kim YI, Na HS, Yoon YW, Han HC,. Local neurokinin-1 receptor in the knee joint contributes to the induction, but not maintenance, of arthritic pain in the rat. Neurosci Lett 2002; 322: 21-24.
    • (2002) Neurosci Lett , vol.322 , pp. 21-24
    • Hong, S.K.1    Han, J.S.2    Min, S.S.3    Hwang, J.M.4    Kim, Y.I.5    Na, H.S.6    Yoon, Y.W.7    Han, H.C.8
  • 30
    • 77249118278 scopus 로고    scopus 로고
    • Substance P and glutamate receptor antagonists improve the anti-arthritic actions of dexamethasone in rats
    • Lam FF, Ng ES,. Substance P and glutamate receptor antagonists improve the anti-arthritic actions of dexamethasone in rats. Br J Pharmacol 2010; 159: 958-969.
    • (2010) Br J Pharmacol , vol.159 , pp. 958-969
    • Lam, F.F.1    Ng, E.S.2
  • 31
    • 33748702691 scopus 로고    scopus 로고
    • Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice
    • Rijnierse A, van Zijl KM, Koster AS, Nijkamp FP, Kraneveld AD,. Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice. Eur J Pharmacol 2006; 548: 150-157.
    • (2006) Eur J Pharmacol , vol.548 , pp. 150-157
    • Rijnierse, A.1    Van Zijl, K.M.2    Koster, A.S.3    Nijkamp, F.P.4    Kraneveld, A.D.5
  • 32
    • 0142058757 scopus 로고    scopus 로고
    • The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness
    • van der Kleij HP, Kraneveld AD, Redegeld FA, Gerard NP, Morteau O, Nijkamp FP,. The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness. Eur J Pharmacol 2003; 476: 249-255.
    • (2003) Eur J Pharmacol , vol.476 , pp. 249-255
    • Van Der Kleij, H.P.1    Kraneveld, A.D.2    Redegeld, F.A.3    Gerard, N.P.4    Morteau, O.5    Nijkamp, F.P.6
  • 33
    • 0027528405 scopus 로고
    • Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo
    • Hirayama Y, Lei YH, Barnes PJ, Rogers DF,. Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo. Br J Pharmacol 1993; 108: 844-851.
    • (1993) Br J Pharmacol , vol.108 , pp. 844-851
    • Hirayama, Y.1    Lei, Y.H.2    Barnes, P.J.3    Rogers, D.F.4
  • 34
    • 58249101397 scopus 로고    scopus 로고
    • Protection from DNBS-induced colitis by the tachykinin NK(1) receptor antagonist SR140333 in rats
    • Ursino MG, Vasina V, De Ponti F,. Protection from DNBS-induced colitis by the tachykinin NK(1) receptor antagonist SR140333 in rats. Eur J Pharmacol 2009; 603: 133-137.
    • (2009) Eur J Pharmacol , vol.603 , pp. 133-137
    • Ursino, M.G.1    Vasina, V.2    De Ponti, F.3
  • 35
    • 79953024700 scopus 로고    scopus 로고
    • Central substance P NK1 receptors are involved in fever induced by LPS but not by IL-1β and CCL3/MIP-1α in rats
    • Reis RC, Brito HO, Fraga D, Cabrini DA, Zampronio AR,. Central substance P NK1 receptors are involved in fever induced by LPS but not by IL-1β and CCL3/MIP-1α in rats. Brain Res 2011; 1384: 161-169.
    • (2011) Brain Res , vol.1384 , pp. 161-169
    • Reis, R.C.1    Brito, H.O.2    Fraga, D.3    Cabrini, D.A.4    Zampronio, A.R.5
  • 36
    • 0033065527 scopus 로고    scopus 로고
    • Effect of MEN 11467, a new tachykinin NK1 receptor antagonist, in acute rectocolitis induced by acetic acid in guinea-pigs
    • Cutrufo C, Evangelista S, Cirillo R, Ciucci A, Conte B, Lopez G, Manzini S, Maggi CA,. Effect of MEN 11467, a new tachykinin NK1 receptor antagonist, in acute rectocolitis induced by acetic acid in guinea-pigs. Eur J Pharmacol 1999; 374: 277-283.
    • (1999) Eur J Pharmacol , vol.374 , pp. 277-283
    • Cutrufo, C.1    Evangelista, S.2    Cirillo, R.3    Ciucci, A.4    Conte, B.5    Lopez, G.6    Manzini, S.7    Maggi, C.A.8
  • 37
    • 84861340551 scopus 로고    scopus 로고
    • Neurogenic airway microvascular leakage induced by toluene inhalation in rats
    • Sakamoto T, Kamijima M, Miyake M,. Neurogenic airway microvascular leakage induced by toluene inhalation in rats. Eur J Pharmacol 2012; 685: 180-185.
    • (2012) Eur J Pharmacol , vol.685 , pp. 180-185
    • Sakamoto, T.1    Kamijima, M.2    Miyake, M.3
  • 39
    • 84859930834 scopus 로고    scopus 로고
    • Rolapitant (SCH 619734): A potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets
    • Duffy RA, Morgan C, Naylor R, Higgins GA, Varty GB, Lachowicz JE, Parker EM,. Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets. Pharmacol Biochem Behav 2012; 102: 95-100.
    • (2012) Pharmacol Biochem Behav , vol.102 , pp. 95-100
    • Duffy, R.A.1    Morgan, C.2    Naylor, R.3    Higgins, G.A.4    Varty, G.B.5    Lachowicz, J.E.6    Parker, E.M.7
  • 40
    • 0035793345 scopus 로고    scopus 로고
    • Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist
    • Ballard TM, Sänger S, Higgins GA,. Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist. Eur J Pharmacol 2001; 412: 255-264.
    • (2001) Eur J Pharmacol , vol.412 , pp. 255-264
    • Ballard, T.M.1    Sänger, S.2    Higgins, G.A.3
  • 41
    • 0035850886 scopus 로고    scopus 로고
    • Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils
    • Cheeta S, Tucci S, Sandhu J, Williams AR, Rupniak NM, File SE,. Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils. Brain Res 2001; 915: 170-175.
    • (2001) Brain Res , vol.915 , pp. 170-175
    • Cheeta, S.1    Tucci, S.2    Sandhu, J.3    Williams, A.R.4    Rupniak, N.M.5    File, S.E.6
  • 43
    • 0037331104 scopus 로고    scopus 로고
    • The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test
    • Varty GB, Cohen-Williams ME, Hunter JC,. The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test. Behav Pharmacol 2003; 14: 87-95.
    • (2003) Behav Pharmacol , vol.14 , pp. 87-95
    • Varty, G.B.1    Cohen-Williams, M.E.2    Hunter, J.C.3
  • 44
    • 45149083874 scopus 로고    scopus 로고
    • Behavioral and pharmacological validation of the gerbil forced-swim test: Effects of neurokinin-1 receptor antagonists
    • Wallace-Boone TL, Newton AE, Wright RN, Lodge NJ, McElroy JF,. Behavioral and pharmacological validation of the gerbil forced-swim test: effects of neurokinin-1 receptor antagonists. Neuropsychopharmacology 2008; 33: 1919-1928.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1919-1928
    • Wallace-Boone, T.L.1    Newton, A.E.2    Wright, R.N.3    Lodge, N.J.4    McElroy, J.F.5
  • 45
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists - Why are they not analgesic in humans?
    • Hill R,. NK1 (substance P) receptor antagonists-why are they not analgesic in humans? Trends Pharmacol Sci 2000; 21: 244-246.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 46
    • 0034406976 scopus 로고    scopus 로고
    • NK1 receptor antagonists - Are they really without effect in the pain clinic?
    • Urban LA, Fox AJ,. NK1 receptor antagonists-are they really without effect in the pain clinic? Trends Pharmacol Sci 2000; 21: 462-464.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 462-464
    • Urban, L.A.1    Fox, A.J.2
  • 47
    • 67650569457 scopus 로고    scopus 로고
    • Tachykinin receptors as therapeutic targets in stress-related disorders
    • Ebner K, Sartori SB, Singewald N,. Tachykinin receptors as therapeutic targets in stress-related disorders. Curr Pharm Des 2009; 15: 1647-1674.
    • (2009) Curr Pharm des , vol.15 , pp. 1647-1674
    • Ebner, K.1    Sartori, S.B.2    Singewald, N.3
  • 48
    • 84871485341 scopus 로고    scopus 로고
    • Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder
    • Michelson D, Hargreaves R, Alexander R, Ceesay P, Hietala J, Lines C, Reines S,. Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder. Int J Neuropsychopharmacol 2012; 20: 1-11.
    • (2012) Int J Neuropsychopharmacol , vol.20 , pp. 1-11
    • Michelson, D.1    Hargreaves, R.2    Alexander, R.3    Ceesay, P.4    Hietala, J.5    Lines, C.6    Reines, S.7
  • 51
    • 67650750902 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonists in the prevention of postoperative nausea and vomiting
    • Diemunsch P, Joshi GP, Brichant J-F,. Neurokinin-1 receptor antagonists in the prevention of postoperative nausea and vomiting. Br J Anaesth 2009; 103: 7-13.
    • (2009) Br J Anaesth , vol.103 , pp. 7-13
    • Diemunsch, P.1    Joshi, G.P.2    Brichant, J.-F.3
  • 52
    • 85047690901 scopus 로고    scopus 로고
    • Aprepitant - A novel NK1-receptor antagonist
    • Patel L, Lindley C,. Aprepitant-a novel NK1-receptor antagonist. Expert Opin Pharmacother 2003; 4: 2279-2296.
    • (2003) Expert Opin Pharmacother , vol.4 , pp. 2279-2296
    • Patel, L.1    Lindley, C.2
  • 53
    • 69749103385 scopus 로고    scopus 로고
    • Aprepitant: A review of its use in the prevention of nausea and vomiting
    • Curran MP, Robinson DM,. Aprepitant: a review of its use in the prevention of nausea and vomiting. Drugs 2009; 69: 1853-1878.
    • (2009) Drugs , vol.69 , pp. 1853-1878
    • Curran, M.P.1    Robinson, D.M.2
  • 54
    • 39549115523 scopus 로고    scopus 로고
    • Fosaprepitant (MK-0517): A neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting
    • Navari RM,. Fosaprepitant (MK-0517): a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting. Expert Opin Investig Drugs 2007; 16: 1977-1985.
    • (2007) Expert Opin Investig Drugs , vol.16 , pp. 1977-1985
    • Navari, R.M.1
  • 58
    • 80755175887 scopus 로고    scopus 로고
    • Results from 2 randomized, double-blind, placebo-controlled studies of the novel NK1 receptor antagonist casopitant in patients with major depressive disorder
    • Erratum in: J Clin Psychopharmacol. 2012; 32: 185
    • Ratti E, Bellew K, Bettica P, Bryson H, Zamuner S, Archer G, Squassante L, Bye A, Trist D, Krishnan KR, Fernandes S,. Results from 2 randomized, double-blind, placebo-controlled studies of the novel NK1 receptor antagonist casopitant in patients with major depressive disorder. J Clin Psychopharmacol 2011; 31: 727-733. Erratum in: J Clin Psychopharmacol. 2012; 32: 185.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 727-733
    • Ratti, E.1    Bellew, K.2    Bettica, P.3    Bryson, H.4    Zamuner, S.5    Archer, G.6    Squassante, L.7    Bye, A.8    Trist, D.9    Krishnan, K.R.10    Fernandes, S.11
  • 59
    • 33947732192 scopus 로고    scopus 로고
    • Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse
    • Elekes K, Helyes Z, Németh J, Sándor K, Pozsgai G, Kereskai L, Börzsei R, Pintér E, Szabõ A, Szolcsányi J,. Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse. Regul Pept 2007; 141: 44-54.
    • (2007) Regul Pept , vol.141 , pp. 44-54
    • Elekes, K.1    Helyes, Z.2    Németh, J.3    Sándor, K.4    Pozsgai, G.5    Kereskai, L.6    Börzsei, R.7    Pintér, E.8    Szabõ, A.9    Szolcsányi, J.10
  • 60
    • 0031815845 scopus 로고    scopus 로고
    • The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics
    • Van Schoor J, Joos GF, Chasson BL, Brouard RJ, Pauwels RA,. The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics. Eur Respir J 1998; 12: 17-23.
    • (1998) Eur Respir J , vol.12 , pp. 17-23
    • Van Schoor, J.1    Joos, G.F.2    Chasson, B.L.3    Brouard, R.J.4    Pauwels, R.A.5
  • 62
    • 0034467519 scopus 로고    scopus 로고
    • Protective effect of the tachykinin NK2 receptor antagonist nepadutant in acute rectocolitis induced by diluted acetic acid in guinea-pigs
    • Cutrufo C, Evangelista S, Cirillo R, Ciucci A, Conte B, Lopez G, Manzini S, Maggi CA,. Protective effect of the tachykinin NK2 receptor antagonist nepadutant in acute rectocolitis induced by diluted acetic acid in guinea-pigs. Neuropeptides 2000; 34: 355-359.
    • (2000) Neuropeptides , vol.34 , pp. 355-359
    • Cutrufo, C.1    Evangelista, S.2    Cirillo, R.3    Ciucci, A.4    Conte, B.5    Lopez, G.6    Manzini, S.7    Maggi, C.A.8
  • 64
    • 79960892635 scopus 로고    scopus 로고
    • Tachykinin receptors antagonism for asthma: A systematic review
    • DOI: 10.1186/1471-2466-11-41
    • Ramalho R, Soares R, Couto N, Moreira A,. Tachykinin receptors antagonism for asthma: a systematic review. BMC Pulm Med 2011; 11: 41. DOI: 10.1186/1471-2466-11-41.
    • (2011) BMC Pulm Med , vol.11 , pp. 41
    • Ramalho, R.1    Soares, R.2    Couto, N.3    Moreira, A.4
  • 65
    • 0029951892 scopus 로고    scopus 로고
    • The effect of inhaled FK224, a tachykinin NK-1 and NK-2 receptor antagonist, on neurokinin A-induced bronchoconstriction in asthmatics
    • Joos GF, Van Schoor J, Kips JC, Pauwels RA,. The effect of inhaled FK224, a tachykinin NK-1 and NK-2 receptor antagonist, on neurokinin A-induced bronchoconstriction in asthmatics. Am J Respir Crit Care Med 1996; 153: 1781-1784.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1781-1784
    • Joos, G.F.1    Van Schoor, J.2    Kips, J.C.3    Pauwels, R.A.4
  • 68
    • 70449934590 scopus 로고    scopus 로고
    • The effect of the tachykinin NK(2) receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in asthmatics
    • Schelfhout V, Van De Velde V, Maggi C, Pauwels R, Joos G,. The effect of the tachykinin NK(2) receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in asthmatics. Ther Adv Respir Dis 2009; 3: 219-226.
    • (2009) Ther Adv Respir Dis , vol.3 , pp. 219-226
    • Schelfhout, V.1    Van De Velde, V.2    Maggi, C.3    Pauwels, R.4    Joos, G.5
  • 69
    • 79956138710 scopus 로고    scopus 로고
    • Randomised clinical trial: The clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea-predominant irritable bowel syndrome
    • Zakko S, Barton G, Weber E, Dunger-Baldauf C, Rühl A,. Randomised clinical trial: the clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2011; 33: 1311-1321.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1311-1321
    • Zakko, S.1    Barton, G.2    Weber, E.3    Dunger-Baldauf, C.4    Rühl, A.5
  • 70
    • 33747169863 scopus 로고    scopus 로고
    • The triple neurokinin-receptor antagonist CS-003 inhibits neurokinin A-induced bronchoconstriction in patients with asthma
    • Schelfhout V, Louis R, Lenz W, Heyrman R, Pauwels R, Joos G,. The triple neurokinin-receptor antagonist CS-003 inhibits neurokinin A-induced bronchoconstriction in patients with asthma. Pulm Pharmacol Ther 2006; 19: 413-418.
    • (2006) Pulm Pharmacol Ther , vol.19 , pp. 413-418
    • Schelfhout, V.1    Louis, R.2    Lenz, W.3    Heyrman, R.4    Pauwels, R.5    Joos, G.6
  • 71
    • 30444455299 scopus 로고    scopus 로고
    • Neuropeptides and their receptors: Innovative science providing novel therapeutic targets
    • Brain SD, Cox HM,. Neuropeptides and their receptors: innovative science providing novel therapeutic targets. Br J Pharmacol 2006; 147 (Suppl. 1): S202-211.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Brain, S.D.1    Cox, H.M.2
  • 73
    • 34547964091 scopus 로고    scopus 로고
    • What makes a CGRP2 receptor?
    • Hay DL,. What makes a CGRP2 receptor? Clin Exp Pharmacol Physiol 2007; 34: 963-971.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 963-971
    • Hay, D.L.1
  • 74
    • 1542346238 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
    • BIBN 4096 BS Clinical Proof of Concept Study Group
    • Olesen J, Diener HC, Husstedt IW, Goadsby PJ, Hall D, Meier U, Pollentier S, Lesko LM, BIBN 4096 BS Clinical Proof of Concept Study Group. Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med 2004; 350: 1104-1110.
    • (2004) N Engl J Med , vol.350 , pp. 1104-1110
    • Olesen, J.1    Diener, H.C.2    Husstedt, I.W.3    Goadsby, P.J.4    Hall, D.5    Meier, U.6    Pollentier, S.7    Lesko, L.M.8
  • 75
    • 84857633644 scopus 로고    scopus 로고
    • New agents for acute treatment of migraine: CGRP receptor antagonists, iNOS inhibitors
    • Hoffmann J, Goadsby PJ,. New agents for acute treatment of migraine: CGRP receptor antagonists, iNOS inhibitors. Curr Treat Options Neurol 2012; 14: 50-59.
    • (2012) Curr Treat Options Neurol , vol.14 , pp. 50-59
    • Hoffmann, J.1    Goadsby, P.J.2
  • 76
    • 0014954352 scopus 로고
    • Polypeptide with broad biological activity: Isolation from small intestine
    • Said SI, Mutt V,. Polypeptide with broad biological activity: isolation from small intestine. Science 1970; 169: 1217-1218.
    • (1970) Science , vol.169 , pp. 1217-1218
    • Said, S.I.1    Mutt, V.2
  • 77
    • 0017128428 scopus 로고
    • Vasoactive intestinal polypeptide: Abundant immunoreactivity in neural cell lines and normal nervous tissue
    • Said SI, Rosenberg RN,. Vasoactive intestinal polypeptide: abundant immunoreactivity in neural cell lines and normal nervous tissue. Science 1976; 192: 907-908.
    • (1976) Science , vol.192 , pp. 907-908
    • Said, S.I.1    Rosenberg, R.N.2
  • 79
    • 0025075727 scopus 로고
    • Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38)
    • Miyata A, Jiang L, Dahl RD, Kitada C, Kubo K, Fujino M, Minamino N, Arimura A,. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem Biophys Res Commun 1990; 170: 643-648.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 643-648
    • Miyata, A.1    Jiang, L.2    Dahl, R.D.3    Kitada, C.4    Kubo, K.5    Fujino, M.6    Minamino, N.7    Arimura, A.8
  • 81
    • 33751062608 scopus 로고    scopus 로고
    • Effect of pituitary adenylate cyclase activating polypeptide-38 on sensory neuropeptide release and neurogenic inflammation in rats and mice
    • Németh J, Reglodi D, Pozsgai G, Szabõ A, Elekes K, Pintér E, Szolcsányi J, Helyes Z,. Effect of pituitary adenylate cyclase activating polypeptide-38 on sensory neuropeptide release and neurogenic inflammation in rats and mice. Neuroscience 2006; 143: 223-230.
    • (2006) Neuroscience , vol.143 , pp. 223-230
    • Németh, J.1    Reglodi, D.2    Pozsgai, G.3    Szabõ, A.4    Elekes, K.5    Pintér, E.6    Szolcsányi, J.7    Helyes, Z.8
  • 82
    • 34548429606 scopus 로고    scopus 로고
    • Anti-inflammatory neuropeptide receptors: New therapeutic targets for immune disorders?
    • Gonzalez-Rey E, Delgado M,. Anti-inflammatory neuropeptide receptors: new therapeutic targets for immune disorders? Trends Pharmacol Sci 2007; 28: 482-491.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 482-491
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 83
    • 0035884986 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide inhibits collagen-induced arthritis: An experimental immunomodulatory therapy
    • Abad C, Martinez C, Leceta J, Gomariz RP, Delgado M,. Pituitary adenylate cyclase-activating polypeptide inhibits collagen-induced arthritis: an experimental immunomodulatory therapy. J Immunol 2001; 167: 3182-3189.
    • (2001) J Immunol , vol.167 , pp. 3182-3189
    • Abad, C.1    Martinez, C.2    Leceta, J.3    Gomariz, R.P.4    Delgado, M.5
  • 84
    • 77957021157 scopus 로고    scopus 로고
    • Regulatory effect of vasoactive intestinal peptide on the balance of Treg and Th17 in collagen-induced arthritis
    • Deng S, Xi Y, Wang H, Hao J, Niu X, Li W, Tao Y, Chen G,. Regulatory effect of vasoactive intestinal peptide on the balance of Treg and Th17 in collagen-induced arthritis. Cell Immunol 2010; 265: 105-110.
    • (2010) Cell Immunol , vol.265 , pp. 105-110
    • Deng, S.1    Xi, Y.2    Wang, H.3    Hao, J.4    Niu, X.5    Li, W.6    Tao, Y.7    Chen, G.8
  • 85
    • 60549089799 scopus 로고    scopus 로고
    • Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis
    • Tan YV, Abad C, Lopez R, Dong H, Liu S, Lee A, Gomariz RP, Leceta J, Waschek JA,. Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2009; 106: 2012-2017.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2012-2017
    • Tan, Y.V.1    Abad, C.2    Lopez, R.3    Dong, H.4    Liu, S.5    Lee, A.6    Gomariz, R.P.7    Leceta, J.8    Waschek, J.A.9
  • 86
    • 33746433951 scopus 로고    scopus 로고
    • VIP prevents experimental multiple sclerosis by downregulating both inflammatory and autoimmune components of the disease
    • Fernandez-Martin A, Gonzalez-Rey E, Chorny A, Martin J, Pozo D, Ganea D, Delgado M,. VIP prevents experimental multiple sclerosis by downregulating both inflammatory and autoimmune components of the disease. Ann N Y Acad Sci 2006; 1070: 276-281.
    • (2006) Ann N y Acad Sci , vol.1070 , pp. 276-281
    • Fernandez-Martin, A.1    Gonzalez-Rey, E.2    Chorny, A.3    Martin, J.4    Pozo, D.5    Ganea, D.6    Delgado, M.7
  • 87
    • 40349093079 scopus 로고    scopus 로고
    • Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP
    • Nemetz N, Abad C, Lawson G, Nobuta H, Chhith S, Duong L, Tse G, Braun J, Waschek JA,. Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP. Int J Cancer 2008; 122: 1803-1809.
    • (2008) Int J Cancer , vol.122 , pp. 1803-1809
    • Nemetz, N.1    Abad, C.2    Lawson, G.3    Nobuta, H.4    Chhith, S.5    Duong, L.6    Tse, G.7    Braun, J.8    Waschek, J.A.9
  • 88
    • 0037379777 scopus 로고    scopus 로고
    • Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease
    • Abad C, Martinez C, Juarranz MG, Arranz A, Leceta J, Delgado M, Gomariz RP,. Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease. Gastroenterology 2003; 124: 961-971.
    • (2003) Gastroenterology , vol.124 , pp. 961-971
    • Abad, C.1    Martinez, C.2    Juarranz, M.G.3    Arranz, A.4    Leceta, J.5    Delgado, M.6    Gomariz, R.P.7
  • 89
    • 43449087928 scopus 로고    scopus 로고
    • Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1
    • Chorny A, Delgado M,. Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1. Am J Pathol 2008; 172: 1297-1307.
    • (2008) Am J Pathol , vol.172 , pp. 1297-1307
    • Chorny, A.1    Delgado, M.2
  • 91
    • 19944429783 scopus 로고    scopus 로고
    • VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production
    • Kojima M, Ito T, Oono T, Hisano T, Igarashi H, Arita Y, Kawabe K, Coy DH, Jensen RT, Nawata H,. VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production. Pancreas 2005; 30: 62-70.
    • (2005) Pancreas , vol.30 , pp. 62-70
    • Kojima, M.1    Ito, T.2    Oono, T.3    Hisano, T.4    Igarashi, H.5    Arita, Y.6    Kawabe, K.7    Coy, D.H.8    Jensen, R.T.9    Nawata, H.10
  • 93
    • 18244374194 scopus 로고    scopus 로고
    • Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock
    • Martínez C, Juarranz Y, Abad C, Arranz A, Miguel BG, Rosignoli F, Leceta J, Gomariz RP,. Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock. J Leukoc Biol 2005; 77: 729-738.
    • (2005) J Leukoc Biol , vol.77 , pp. 729-738
    • Martínez, C.1    Juarranz, Y.2    Abad, C.3    Arranz, A.4    Miguel, B.G.5    Rosignoli, F.6    Leceta, J.7    Gomariz, R.P.8
  • 95
    • 78650588402 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis
    • Abad C, Tan YV, Lopez R, Nobuta H, Dong H, Phan P, Feng JM, Campagnoni AT, Waschek JA,. Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2010; 107: 19555-19560.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19555-19560
    • Abad, C.1    Tan, Y.V.2    Lopez, R.3    Nobuta, H.4    Dong, H.5    Phan, P.6    Feng, J.M.7    Campagnoni, A.T.8    Waschek, J.A.9
  • 97
    • 78650217363 scopus 로고    scopus 로고
    • Investigation of carbachol and PACAP38 in a human model of migraine
    • Schytz HW,. Investigation of carbachol and PACAP38 in a human model of migraine. Dan Med Bull 2010; 57: B4223.
    • (2010) Dan Med Bull , vol.57
    • Schytz, H.W.1
  • 100
    • 31544470059 scopus 로고    scopus 로고
    • Immobilized alpha-melanocyte stimulating hormone 10-13 (GKPV) inhibits tumor necrosis factor-alpha stimulated NF-kappaB activity
    • Kelly JM, Moir AJ, Carlson K, Yang Y, MacNeil S, Haycock JW,. Immobilized alpha-melanocyte stimulating hormone 10-13 (GKPV) inhibits tumor necrosis factor-alpha stimulated NF-kappaB activity. Peptides 2006; 27: 431-437.
    • (2006) Peptides , vol.27 , pp. 431-437
    • Kelly, J.M.1    Moir, A.J.2    Carlson, K.3    Yang, Y.4    Macneil, S.5    Haycock, J.W.6
  • 101
    • 17044392279 scopus 로고    scopus 로고
    • The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages
    • Taylor AW,. The immunomodulating neuropeptide alpha-melanocyte- stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages. J Neuroimmunol 2005; 162: 43-50.
    • (2005) J Neuroimmunol , vol.162 , pp. 43-50
    • Taylor, A.W.1
  • 102
    • 44149087565 scopus 로고    scopus 로고
    • Anti-inflammatory action of alpha-melanocyte stimulating hormone (alpha-MSH) in anti-CD3/CD28-mediated spleen and CD4(+)CD25(-) T cells and a partial participation of IL-10
    • Chang SH, Jung EJ, Lim DG, Park YH, Wee YM, Kim JH, Kim YH, Choi MY, Koo SK, Choi KD, Han DJ, Kim SC,. Anti-inflammatory action of alpha-melanocyte stimulating hormone (alpha-MSH) in anti-CD3/CD28-mediated spleen and CD4(+)CD25(-) T cells and a partial participation of IL-10. Immunol Lett 2008; 118: 44-48.
    • (2008) Immunol Lett , vol.118 , pp. 44-48
    • Chang, S.H.1    Jung, E.J.2    Lim, D.G.3    Park, Y.H.4    Wee, Y.M.5    Kim, J.H.6    Kim, Y.H.7    Choi, M.Y.8    Koo, S.K.9    Choi, K.D.10    Han, D.J.11    Kim, S.C.12
  • 103
    • 77949412581 scopus 로고    scopus 로고
    • The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells
    • Rennalls LP, Seidl T, Larkin JM, Wellbrock C, Gore ME, Eisen T, Bruno L,. The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells. Immunology 2010; 129: 610-619.
    • (2010) Immunology , vol.129 , pp. 610-619
    • Rennalls, L.P.1    Seidl, T.2    Larkin, J.M.3    Wellbrock, C.4    Gore, M.E.5    Eisen, T.6    Bruno, L.7
  • 107
    • 79960189090 scopus 로고    scopus 로고
    • Immunosuppressive activity of a novel peptide analog of α-melanocyte stimulating hormone (α-MSH) in experimental autoimmune uveitis
    • Edling AE, Gomes D, Weeden T, Dzuris J, Stefano J, Pan C, Williams J, Kaplan J, Perricone MA,. Immunosuppressive activity of a novel peptide analog of α-melanocyte stimulating hormone (α-MSH) in experimental autoimmune uveitis. J Neuroimmunol 2011; 236: 1-9.
    • (2011) J Neuroimmunol , vol.236 , pp. 1-9
    • Edling, A.E.1    Gomes, D.2    Weeden, T.3    Dzuris, J.4    Stefano, J.5    Pan, C.6    Williams, J.7    Kaplan, J.8    Perricone, M.A.9
  • 108
    • 21044431964 scopus 로고    scopus 로고
    • The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: Potential therapeutic applications
    • Gravanis A, Margioris AN,. The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: potential therapeutic applications. Curr Med Chem 2005; 12: 1503-1512.
    • (2005) Curr Med Chem , vol.12 , pp. 1503-1512
    • Gravanis, A.1    Margioris, A.N.2
  • 109
    • 33646779859 scopus 로고    scopus 로고
    • Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease
    • Gonzalez-Rey E, Fernandez-Martin A, Chorny A, Delgado M,. Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease. Gut 2006; 55: 824-832.
    • (2006) Gut , vol.55 , pp. 824-832
    • Gonzalez-Rey, E.1    Fernandez-Martin, A.2    Chorny, A.3    Delgado, M.4
  • 112
    • 33747762945 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses
    • Kokkotou E, Torres D, Moss AC, O'Brien M, Grigoriadis DE, Karalis K, Pothoulakis C,. Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses. J Immunol 2006; 177: 3355-3361.
    • (2006) J Immunol , vol.177 , pp. 3355-3361
    • Kokkotou, E.1    Torres, D.2    Moss, A.C.3    O'Brien, M.4    Grigoriadis, D.E.5    Karalis, K.6    Pothoulakis, C.7
  • 113
    • 33847080383 scopus 로고    scopus 로고
    • Therapeutic effect of urocortin on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of regulatory T cells
    • Gonzalez-Rey E, Chorny A, Varela N, O'Valle F, Delgado M,. Therapeutic effect of urocortin on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of regulatory T cells. Arthritis Rheum 2007; 56: 531-543.
    • (2007) Arthritis Rheum , vol.56 , pp. 531-543
    • Gonzalez-Rey, E.1    Chorny, A.2    Varela, N.3    O'Valle, F.4    Delgado, M.5
  • 115
    • 0031570394 scopus 로고    scopus 로고
    • Stress and autoimmunity: The neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system
    • Poliak S, Mor F, Conlon P, Wong T, Ling N, Rivier J, Vale W, Steinman L,. Stress and autoimmunity: the neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system. J Immunol 1997; 158: 5751-5756.
    • (1997) J Immunol , vol.158 , pp. 5751-5756
    • Poliak, S.1    Mor, F.2    Conlon, P.3    Wong, T.4    Ling, N.5    Rivier, J.6    Vale, W.7    Steinman, L.8
  • 116
    • 3042597423 scopus 로고    scopus 로고
    • Vascular actions of calcitonin gene-related peptide and adrenomedullin
    • Brain SD, Grant AD,. Vascular actions of calcitonin gene-related peptide and adrenomedullin. Physiol Rev 2004; 84: 903-934.
    • (2004) Physiol Rev , vol.84 , pp. 903-934
    • Brain, S.D.1    Grant, A.D.2
  • 117
    • 35349012981 scopus 로고    scopus 로고
    • Adrenomedullin reduces the severity of cerulein-induced acute pancreatitis
    • Onur OE, Guneysel O, Akoglu H, Denizbasi A, Onur E,. Adrenomedullin reduces the severity of cerulein-induced acute pancreatitis. Peptides 2007; 28: 2179-2183.
    • (2007) Peptides , vol.28 , pp. 2179-2183
    • Onur, O.E.1    Guneysel, O.2    Akoglu, H.3    Denizbasi, A.4    Onur, E.5
  • 118
    • 77951254830 scopus 로고    scopus 로고
    • Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats
    • Yang J, Wu R, Zhou M, Wang P,. Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats. Peptides 2010; 31: 872-877.
    • (2010) Peptides , vol.31 , pp. 872-877
    • Yang, J.1    Wu, R.2    Zhou, M.3    Wang, P.4
  • 121
    • 80655126779 scopus 로고    scopus 로고
    • Adrenomedullin inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and MMPs, COX-2 and PGE2 production
    • Lee EG, Lee SI, Chae HJ, Park SJ, Lee YC, Yoo WH,. Adrenomedullin inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and MMPs, COX-2 and PGE2 production. Inflammation 2011; 34: 335-343.
    • (2011) Inflammation , vol.34 , pp. 335-343
    • Lee, E.G.1    Lee, S.I.2    Chae, H.J.3    Park, S.J.4    Lee, Y.C.5    Yoo, W.H.6
  • 123
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and its receptor family
    • Patel YC,. Somatostatin and its receptor family. Front Neuroendocrinol 1999; 20: 157-198.
    • (1999) Front Neuroendocrinol , vol.20 , pp. 157-198
    • Patel, Y.C.1
  • 124
    • 0033773979 scopus 로고    scopus 로고
    • Somatostatin and somatostatin receptors in the immune system: A review
    • ten Bokum AM, Hofland LJ, van Hagen PM,. Somatostatin and somatostatin receptors in the immune system: a review. Eur Cytokine Netw 2000; 11: 161-176.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 161-176
    • Ten Bokum, A.M.1    Hofland, L.J.2    Van Hagen, P.M.3
  • 126
    • 33749443206 scopus 로고    scopus 로고
    • Inhibitory effect of somatostatin on inflammation and nociception
    • Pintér E, Helyes Z, Szolcsányi J,. Inhibitory effect of somatostatin on inflammation and nociception. Pharmacol Ther 2006; 112: 440-456.
    • (2006) Pharmacol Ther , vol.112 , pp. 440-456
    • Pintér, E.1    Helyes, Z.2    Szolcsányi, J.3
  • 127
    • 0031728130 scopus 로고    scopus 로고
    • Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors
    • Szolcsányi J, Pintér E, Helyes Z, Oroszi G, Németh J,. Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors. Br J Pharmacol 1998; 125: 916-922.
    • (1998) Br J Pharmacol , vol.125 , pp. 916-922
    • Szolcsányi, J.1    Pintér, E.2    Helyes, Z.3    Oroszi, G.4    Németh, J.5
  • 133
    • 0032772728 scopus 로고    scopus 로고
    • SSTR2A is the dominant somatostatin receptor subtype expressed by inflammatory cells, is widely expressed and directly regulates T cell IFN-gamma release
    • Elliott DE, Li J, Blum AM, Metwali A, Patel YC, Weinstock JV,. SSTR2A is the dominant somatostatin receptor subtype expressed by inflammatory cells, is widely expressed and directly regulates T cell IFN-gamma release. Eur J Immunol 1999; 29: 2454-2463.
    • (1999) Eur J Immunol , vol.29 , pp. 2454-2463
    • Elliott, D.E.1    Li, J.2    Blum, A.M.3    Metwali, A.4    Patel, Y.C.5    Weinstock, J.V.6
  • 134
    • 0027515873 scopus 로고
    • In vivo inhibition of the rat primary antibody response to antigenic stimulation by somatostatin
    • Eglezos A, Andrews PV, Helme RD,. In vivo inhibition of the rat primary antibody response to antigenic stimulation by somatostatin. Immunol Cell Biol 1993; 71: 125-129.
    • (1993) Immunol Cell Biol , vol.71 , pp. 125-129
    • Eglezos, A.1    Andrews, P.V.2    Helme, R.D.3
  • 135
    • 0027328678 scopus 로고
    • Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin
    • Wiedermann CJ, Reinisch N, Braunsteiner H,. Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin. Blood 1993; 82: 954-960.
    • (1993) Blood , vol.82 , pp. 954-960
    • Wiedermann, C.J.1    Reinisch, N.2    Braunsteiner, H.3
  • 136
    • 79961122138 scopus 로고    scopus 로고
    • Differential antiinflammatory and antinociceptive effects of the somatostatin analogs octreotide and pasireotide in a mouse model of immune-mediated arthritis
    • Imhof AK, Glück L, Gajda M, Lupp A, Bräuer R, Schaible HG, Schulz S,. Differential antiinflammatory and antinociceptive effects of the somatostatin analogs octreotide and pasireotide in a mouse model of immune-mediated arthritis. Arthritis Rheum 2011; 63: 2352-2362.
    • (2011) Arthritis Rheum , vol.63 , pp. 2352-2362
    • Imhof, A.K.1    Glück, L.2    Gajda, M.3    Lupp, A.4    Bräuer, R.5    Schaible, H.G.6    Schulz, S.7
  • 143
    • 0027469452 scopus 로고
    • Octreotide effectively decreases mucosal damage in experimental colitis
    • Eliakim R, Karmeli F, Okon E, Rachmilewitz D,. Octreotide effectively decreases mucosal damage in experimental colitis. Gut 1993; 34: 264-269.
    • (1993) Gut , vol.34 , pp. 264-269
    • Eliakim, R.1    Karmeli, F.2    Okon, E.3    Rachmilewitz, D.4
  • 145
    • 12344308382 scopus 로고    scopus 로고
    • Octreotide ameliorates sepsis-induced pelvic inflammation in female rats by a neutrophil-dependent mechanism
    • Sener G, Cetinel S, Erkanli G, Gedik N, Yeǧen BC,. Octreotide ameliorates sepsis-induced pelvic inflammation in female rats by a neutrophil-dependent mechanism. Peptides 2005; 26: 493-499.
    • (2005) Peptides , vol.26 , pp. 493-499
    • Sener, G.1    Cetinel, S.2    Erkanli, G.3    Gedik, N.4    Yeǧen, B.C.5
  • 146
    • 79959967389 scopus 로고    scopus 로고
    • Somatostatin and octreotide on the treatment of acute pancreatitis - Basic and clinical studies for three decades
    • Li J, Wang R, Tang C,. Somatostatin and octreotide on the treatment of acute pancreatitis-basic and clinical studies for three decades. Curr Pharm Des 2011; 17: 1594-1601.
    • (2011) Curr Pharm des , vol.17 , pp. 1594-1601
    • Li, J.1    Wang, R.2    Tang, C.3
  • 147
    • 84872082771 scopus 로고    scopus 로고
    • Protective effects of saizen in combination with stilamin on intestinal mucosa of a rabbit model of severe acute pancreatitis
    • Lu Y, Yu Y, Yang M, Liu H, Li B, Xu H,. Protective effects of saizen in combination with stilamin on intestinal mucosa of a rabbit model of severe acute pancreatitis. Pancreas 2013; 42: 102-107.
    • (2013) Pancreas , vol.42 , pp. 102-107
    • Lu, Y.1    Yu, Y.2    Yang, M.3    Liu, H.4    Li, B.5    Xu, H.6
  • 148
    • 43549110929 scopus 로고    scopus 로고
    • Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders
    • Gonzalez-Rey E, Delgado M,. Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders. Mol Cell Endocrinol 2008; 286: 135-140.
    • (2008) Mol Cell Endocrinol , vol.286 , pp. 135-140
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 150
    • 34047199656 scopus 로고    scopus 로고
    • Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses
    • Gonzalez-Rey E, Chorny A, Del Moral RG, Varela N, Delgado M,. Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses. Ann Rheum Dis 2007; 66: 582-588.
    • (2007) Ann Rheum Dis , vol.66 , pp. 582-588
    • Gonzalez-Rey, E.1    Chorny, A.2    Del Moral, R.G.3    Varela, N.4    Delgado, M.5
  • 152
    • 33645080443 scopus 로고    scopus 로고
    • Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia
    • Gonzalez-Rey E, Chorny A, Robledo G, Delgado M,. Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia. J Exp Med 2006; 203: 563-571.
    • (2006) J Exp Med , vol.203 , pp. 563-571
    • Gonzalez-Rey, E.1    Chorny, A.2    Robledo, G.3    Delgado, M.4
  • 154
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely AJ, Tschöp M, Heiman ML, Ghigo E,. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev 2004; 25: 426-457.
    • (2004) Endocr Rev , vol.25 , pp. 426-457
    • Van Der Lely, A.J.1    Tschöp, M.2    Heiman, M.L.3    Ghigo, E.4
  • 157
    • 50949098239 scopus 로고    scopus 로고
    • Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria
    • Chorny A, Anderson P, Gonzalez-Rey E, Delgado M,. Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria. J Immunol 2008; 180: 8369-8377.
    • (2008) J Immunol , vol.180 , pp. 8369-8377
    • Chorny, A.1    Anderson, P.2    Gonzalez-Rey, E.3    Delgado, M.4
  • 158
    • 84866363001 scopus 로고    scopus 로고
    • Use of ghrelin as a treatment for inflammatory bowel disease: Mechanistic considerations
    • Deboer MD,. Use of ghrelin as a treatment for inflammatory bowel disease: mechanistic considerations. Int J Pept 2011; 2011: 189242.
    • (2011) Int J Pept , vol.2011 , pp. 189242
    • Deboer, M.D.1
  • 159
    • 34447255940 scopus 로고    scopus 로고
    • The galanin peptide family: Receptor pharmacology, pleiotropic biological actions, and implications in health and disease
    • Lang R, Gundlach AL, Kofler B,. The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol Ther 2007; 115: 177-207.
    • (2007) Pharmacol Ther , vol.115 , pp. 177-207
    • Lang, R.1    Gundlach, A.L.2    Kofler, B.3
  • 160
    • 84863376198 scopus 로고    scopus 로고
    • Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model
    • Zhang L, Yu W, Schroedter I, Kong J, Vrontakis M,. Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model. PLoS ONE 2012; 7: e33901.
    • (2012) PLoS ONE , vol.7
    • Zhang, L.1    Yu, W.2    Schroedter, I.3    Kong, J.4    Vrontakis, M.5
  • 161
    • 33947591092 scopus 로고    scopus 로고
    • Chronic administration of galanin attenuates the TNBS-induced colitis in rats
    • Talero E, Sánchez-Fidalgo S, Calvo JR, Motilva V,. Chronic administration of galanin attenuates the TNBS-induced colitis in rats. Regul Pept 2007; 141: 96-104.
    • (2007) Regul Pept , vol.141 , pp. 96-104
    • Talero, E.1    Sánchez-Fidalgo, S.2    Calvo, J.R.3    Motilva, V.4
  • 162
    • 3543112679 scopus 로고    scopus 로고
    • Galanin contributes to the excess colonic fluid secretion observed in dextran sulfate sodium murine colitis
    • Matkowskyj KA, Nathaniel R, Prasad R, Weihrauch D, Rao M, Benya RV,. Galanin contributes to the excess colonic fluid secretion observed in dextran sulfate sodium murine colitis. Inflamm Bowel Dis 2004; 10: 408-416.
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 408-416
    • Matkowskyj, K.A.1    Nathaniel, R.2    Prasad, R.3    Weihrauch, D.4    Rao, M.5    Benya, R.V.6
  • 166
    • 42949164536 scopus 로고    scopus 로고
    • Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin
    • Schmidhuber SM, Starr A, Wynick D, Kofler B, Brain SD,. Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin. J Mol Neurosci 2008; 34: 149-155.
    • (2008) J Mol Neurosci , vol.34 , pp. 149-155
    • Schmidhuber, S.M.1    Starr, A.2    Wynick, D.3    Kofler, B.4    Brain, S.D.5
  • 167
    • 0030933655 scopus 로고    scopus 로고
    • A potent and selective endogenous agonist for the mu-opiate receptor
    • Zadina JE, Hackler L, Ge LJ, Kastin AJ,. A potent and selective endogenous agonist for the mu-opiate receptor. Nature 1997; 386: 499-502.
    • (1997) Nature , vol.386 , pp. 499-502
    • Zadina, J.E.1    Hackler, L.2    Ge, L.J.3    Kastin, A.J.4
  • 168
    • 0031426851 scopus 로고    scopus 로고
    • Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex
    • Hackler L, Zadina JE, Ge LJ, Kastin AJ,. Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex. Peptides 1997; 18: 1635-1639.
    • (1997) Peptides , vol.18 , pp. 1635-1639
    • Hackler, L.1    Zadina, J.E.2    Ge, L.J.3    Kastin, A.J.4
  • 169
    • 0033103146 scopus 로고    scopus 로고
    • Endomorphin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons in vitro
    • Wu SY, Dun SL, Wright MT, Chang JK, Dun NJ,. Endomorphin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons in vitro. Neuroscience 1999; 89: 317-321.
    • (1999) Neuroscience , vol.89 , pp. 317-321
    • Wu, S.Y.1    Dun, S.L.2    Wright, M.T.3    Chang, J.K.4    Dun, N.J.5
  • 170
    • 0036300956 scopus 로고    scopus 로고
    • Opioid peptides endomorphin-1 and endomorphin-2 in the immune system in humans and in a rodent model of inflammation
    • Jessop DS, Richards LJ, Harbuz MS,. Opioid peptides endomorphin-1 and endomorphin-2 in the immune system in humans and in a rodent model of inflammation. Ann N Y Acad Sci 2002; 966: 456-463.
    • (2002) Ann N y Acad Sci , vol.966 , pp. 456-463
    • Jessop, D.S.1    Richards, L.J.2    Harbuz, M.S.3
  • 171
    • 0032536431 scopus 로고    scopus 로고
    • Immunoreactivity for endomorphin-2 occurs in primary afferents in rats and monkey
    • Pierce TL, Grahek MD, Wessendorf MW,. Immunoreactivity for endomorphin-2 occurs in primary afferents in rats and monkey. Neuroreport 1998; 9: 385-389.
    • (1998) Neuroreport , vol.9 , pp. 385-389
    • Pierce, T.L.1    Grahek, M.D.2    Wessendorf, M.W.3
  • 173
    • 81355156238 scopus 로고    scopus 로고
    • Guide to receptors and channels (GRAC), 5th edition
    • Alexander SP, Mathie A, Peters JA,. Guide to receptors and channels (GRAC), 5th edition. Br J Pharmacol 2011; 164 (Suppl. 1): S1-324.
    • (2011) Br J Pharmacol , vol.164 , Issue.SUPPL. 1
    • Alexander, S.P.1    Mathie, A.2    Peters, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.