Isolation of relatively large amounts of endomorphin-1 and endomorphin- 2 from human brain cortex

Peptides

Volumn 18, Issue 10, 1997, Pages 1635-1639

  Hackler, Laszlo ^a   Zadina, James E ^a   Ge, Lin Jun ^a   Kastin, Abba J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain; Endomorphins; HPLC; Human; Opiate; Peptide

Indexed keywords

ENDOMORPHIN 1; ENDOMORPHIN 2; ENDORPHIN DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BRAIN CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION; RADIOIMMUNOASSAY; SOLID PHASE EXTRACTION;

AMINO ACID SEQUENCE; ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; CATTLE; CEREBRAL CORTEX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; HUMANS; OLIGOPEPTIDES; RADIOIMMUNOASSAY; RECEPTORS, OPIOID, MU;

EID: 0031426851     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(97)00259-3     Document Type: Article

References (6)

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4. Mains R. E., Dickerson I. M., May V., Stoffers D. A., Perkins S. N., Ouafik L., Husten E. J., Eipper B. A. Cellular and molecular aspects of peptide hormone biosynthesis. Front. Neuroendocrinol. 11:1990;52-89.
5. Zadina J. E., Kastin A. J., Ge L.-J., Hackler L. Mu, delta, and kappa opiate receptor binding of Tyr-MIF-1 and of Tyr-W-MIF-1, its active fragments, and two potent analogs. Life Sci. 55:1994;L461-L466.
6. Zadina J. E., Hackler L., Ge L.-J., Kastin A. J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature (Lond.). 386:1997;499-502.