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Volumn 45, Issue 4, 2006, Pages 215-220

Defensive and pathological functions of the gastrointestinal NK3 receptor

Author keywords

Intestinal motility; NK3; Osanetant; Tachykinins; Talnetant; Visceral pain

Indexed keywords

N (ALPHA ETHYLBENZYL) 3 METHYL 2 PHENYL 4 QUINOLINECARBOXAMIDE; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; OSANETANT; SB 235375; TACHYKININ; TALNETANT; UNCLASSIFIED DRUG;

EID: 33750977552     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2005.08.026     Document Type: Article
Times cited : (8)

References (56)
  • 1
    • 0035836471 scopus 로고    scopus 로고
    • Comparison of the effects of neurokinin-3 receptor blockade on two forms of slow synaptic transmission in myenteric AH neurons
    • Alex G., Kunze W.A.A., Furness J.B., and Clerc N. Comparison of the effects of neurokinin-3 receptor blockade on two forms of slow synaptic transmission in myenteric AH neurons. Neurosci. 104 (2001) 263-269
    • (2001) Neurosci. , vol.104 , pp. 263-269
    • Alex, G.1    Kunze, W.A.A.2    Furness, J.B.3    Clerc, N.4
  • 2
    • 0028985234 scopus 로고
    • 3 receptor antagonists in modulation of visceral hypersensitivity
    • 3 receptor antagonists in modulation of visceral hypersensitivity. Br. J. Pharmacol. 114 (1995) 558-562
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 558-562
    • Banner, S.E.1    Sanger, G.J.2
  • 3
    • 0022351090 scopus 로고
    • Search for a physiological role of substance P in gastrointestinal motility
    • Barthó L., and Holzer P. Search for a physiological role of substance P in gastrointestinal motility. Neuroscience 16 (1985) 1-32
    • (1985) Neuroscience , vol.16 , pp. 1-32
    • Barthó, L.1    Holzer, P.2
  • 4
    • 0345251975 scopus 로고    scopus 로고
    • Tachykinin receptors are involved in the "local efferent" motor response to capsaicin in the guinea-pig small intestine and oesophagus
    • Barthó L., Lenard L., Patacchini R., Halmai V., Wilhelm M., Holzer P., and Maggi C.A. Tachykinin receptors are involved in the "local efferent" motor response to capsaicin in the guinea-pig small intestine and oesophagus. Neurosci. 90 (1999) 221-228
    • (1999) Neurosci. , vol.90 , pp. 221-228
    • Barthó, L.1    Lenard, L.2    Patacchini, R.3    Halmai, V.4    Wilhelm, M.5    Holzer, P.6    Maggi, C.A.7
  • 6
    • 3042681023 scopus 로고    scopus 로고
    • Immunohistochemical characterization of putative primary afferent (sensory) myenteric neurons in human small intestine
    • Brehmer A., Croner R., Dimmler A., Papadopoulos T., Schrodl F., and Neuhuber W. Immunohistochemical characterization of putative primary afferent (sensory) myenteric neurons in human small intestine. Auton. Neurosci. 112 (2004) 49-59
    • (2004) Auton. Neurosci. , vol.112 , pp. 49-59
    • Brehmer, A.1    Croner, R.2    Dimmler, A.3    Papadopoulos, T.4    Schrodl, F.5    Neuhuber, W.6
  • 7
    • 0032977250 scopus 로고    scopus 로고
    • Long-term effects of synaptic activation at low frequency on excitability of myenteric AH neurons
    • Clerc N., Furness J.B., Kunze W.A.A., Thomas E.A., and Bertrand P.P. Long-term effects of synaptic activation at low frequency on excitability of myenteric AH neurons. Neurosci. 90 (1999) 279-289
    • (1999) Neurosci. , vol.90 , pp. 279-289
    • Clerc, N.1    Furness, J.B.2    Kunze, W.A.A.3    Thomas, E.A.4    Bertrand, P.P.5
  • 9
    • 0036447321 scopus 로고    scopus 로고
    • Role of tachykinergic and cholinergic pathways in modulating canine gastric tone and compliance in vivo
    • Crema F., Moro E., Nardelli G., De Ponti F., Frigo G., and Crema A. Role of tachykinergic and cholinergic pathways in modulating canine gastric tone and compliance in vivo. Pharmacol. Res. 45 (2002) 341-347
    • (2002) Pharmacol. Res. , vol.45 , pp. 341-347
    • Crema, F.1    Moro, E.2    Nardelli, G.3    De Ponti, F.4    Frigo, G.5    Crema, A.6
  • 11
    • 0030932882 scopus 로고    scopus 로고
    • Rectal distension-induced colonic net water secretion in rats involves tachykinins, capsaicin sensory and vagus nerves
    • Eutamene H., Theodorou V., Fioramonti J., and Bueno L. Rectal distension-induced colonic net water secretion in rats involves tachykinins, capsaicin sensory and vagus nerves. Gastroenterol. 112 (1997) 1595-1602
    • (1997) Gastroenterol. , vol.112 , pp. 1595-1602
    • Eutamene, H.1    Theodorou, V.2    Fioramonti, J.3    Bueno, L.4
  • 15
    • 0142165222 scopus 로고    scopus 로고
    • 3 receptors in the modulation of visceral hypersensitivity in the rat
    • 3 receptors in the modulation of visceral hypersensitivity in the rat. Neurosci. Lett. 351 (2003) 59-62
    • (2003) Neurosci. Lett. , vol.351 , pp. 59-62
    • Gaudreau, G.-A.1    Plourde, V.2
  • 16
    • 0032943986 scopus 로고    scopus 로고
    • Involvement of tachykinin receptors in sensitisation to cow's milk proteins in guinea-pigs
    • Gay J., Fioramonti J., Garcia-Villar R., Edmonds-Alt X., and Bueno L. Involvement of tachykinin receptors in sensitisation to cow's milk proteins in guinea-pigs. Gut 44 (1999) 497-503
    • (1999) Gut , vol.44 , pp. 497-503
    • Gay, J.1    Fioramonti, J.2    Garcia-Villar, R.3    Edmonds-Alt, X.4    Bueno, L.5
  • 17
    • 0032545093 scopus 로고    scopus 로고
    • 3 receptor-mediated colonic ion transport in the guinea-pig
    • 3 receptor-mediated colonic ion transport in the guinea-pig. Eur. J. Pharmacol. 363 (1998) 161-168
    • (1998) Eur. J. Pharmacol. , vol.363 , pp. 161-168
    • Goldhill, J.1    Angel, I.2
  • 18
    • 0034809037 scopus 로고    scopus 로고
    • Neural regulation of in vitro giant contractions in the rat colon
    • Gonzalez A., and Sarna S.K. Neural regulation of in vitro giant contractions in the rat colon. Am. J. Physiol. 281 (2001) G275-G282
    • (2001) Am. J. Physiol. , vol.281
    • Gonzalez, A.1    Sarna, S.K.2
  • 20
    • 18244395370 scopus 로고    scopus 로고
    • Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pig's
    • Hay D.W.P., Giardina G.A.M., Griswold D.E., et al. Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pig's. J. Pharmacol. Exp. Ther. 300 (2002) 314-323
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 314-323
    • Hay, D.W.P.1    Giardina, G.A.M.2    Griswold, D.E.3
  • 21
    • 0035144145 scopus 로고    scopus 로고
    • Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine
    • Hens J., Vanderwinden J.M., De Laet M.H., Scheuermann D.W., and Timmermans J.P. Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine. J. Neurochem. 76 (2001) 464-471
    • (2001) J. Neurochem. , vol.76 , pp. 464-471
    • Hens, J.1    Vanderwinden, J.M.2    De Laet, M.H.3    Scheuermann, D.W.4    Timmermans, J.P.5
  • 22
    • 0035656920 scopus 로고    scopus 로고
    • Tachykinin receptors in the gut: physiological and pathological implications
    • Holzer P., and Holzer-Petsche U. Tachykinin receptors in the gut: physiological and pathological implications. Curr. Opin. Pharmacol. 1 (2001) 583-590
    • (2001) Curr. Opin. Pharmacol. , vol.1 , pp. 583-590
    • Holzer, P.1    Holzer-Petsche, U.2
  • 23
    • 0031595205 scopus 로고    scopus 로고
    • 2 receptor mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro
    • 2 receptor mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro. Neuropharmacology 37 (1998) 131-138
    • (1998) Neuropharmacology , vol.37 , pp. 131-138
    • Holzer, P.1    Lippe, I.T.2    Heinemann, A.3    Bartho, L.4
  • 24
    • 0032831255 scopus 로고    scopus 로고
    • Neurons bearing NK3 tachykinin receptors in the guinea-pig ileum revealed by specific binding of fluorescently labelled agonists
    • Jenkinson K.M., Morgan J.M., Furness J.B., and Southwell B.R. Neurons bearing NK3 tachykinin receptors in the guinea-pig ileum revealed by specific binding of fluorescently labelled agonists. Histochem. Cell Biol. 112 (1999) 233-246
    • (1999) Histochem. Cell Biol. , vol.112 , pp. 233-246
    • Jenkinson, K.M.1    Morgan, J.M.2    Furness, J.B.3    Southwell, B.R.4
  • 25
    • 2342521332 scopus 로고    scopus 로고
    • Neurokinin-1 and -3 receptor blockade inhibits slow excitatory synaptic transmission in myenteric neurons and reveals slow inhibitory input
    • Johnson P.J., and Bornstein J.C. Neurokinin-1 and -3 receptor blockade inhibits slow excitatory synaptic transmission in myenteric neurons and reveals slow inhibitory input. Neurosci. 126 (2004) 137-147
    • (2004) Neurosci. , vol.126 , pp. 137-147
    • Johnson, P.J.1    Bornstein, J.C.2
  • 26
    • 0029763623 scopus 로고    scopus 로고
    • Analysis of contributions of acetylcholine and tachykinins to neuro-neuronal transmission in motility reflexes in the guinea-pig ileum
    • Johnson P.J., Bornstein J.C., Yuan S.Y., and Funess J.B. Analysis of contributions of acetylcholine and tachykinins to neuro-neuronal transmission in motility reflexes in the guinea-pig ileum. Br. J. Pharmacol. 118 (1996) 973-983
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 973-983
    • Johnson, P.J.1    Bornstein, J.C.2    Yuan, S.Y.3    Funess, J.B.4
  • 27
    • 0031595235 scopus 로고    scopus 로고
    • 3 receptors in synaptic transmission during motility reflexes in the guinea-pig ileum
    • 3 receptors in synaptic transmission during motility reflexes in the guinea-pig ileum. Br. J. Pharmacol. 124 (1998) 1375-1384
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 1375-1384
    • Johnson, P.J.1    Bornstein, J.C.2    Burcher, E.3
  • 28
    • 0032952503 scopus 로고    scopus 로고
    • Role of neurokinin 3 receptors on responses to colorectal distension in the rat: Electrophysiological and behavioural studies
    • Julia V., Su X., Bueno L., and Gebhart G.F. Role of neurokinin 3 receptors on responses to colorectal distension in the rat: Electrophysiological and behavioural studies. Gastroenterol. 116 (1999) 1124-1131
    • (1999) Gastroenterol. , vol.116 , pp. 1124-1131
    • Julia, V.1    Su, X.2    Bueno, L.3    Gebhart, G.F.4
  • 30
    • 0034807739 scopus 로고    scopus 로고
    • Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia
    • Kamp E.H., Beck D.R., and Gebhart G.F. Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia. J. Pharmacol. Exp. Ther. 299 (2001) 105-113
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 105-113
    • Kamp, E.H.1    Beck, D.R.2    Gebhart, G.F.3
  • 31
    • 0033767709 scopus 로고    scopus 로고
    • Effects of tachykinin receptor agonists and antagonists on the guinea-pig isolated oesophagus
    • Kerr K.P. Effects of tachykinin receptor agonists and antagonists on the guinea-pig isolated oesophagus. Clin. Exp. Pharmacol. Physiol. 27 (2000) 934-938
    • (2000) Clin. Exp. Pharmacol. Physiol. , vol.27 , pp. 934-938
    • Kerr, K.P.1
  • 32
    • 13444283733 scopus 로고    scopus 로고
    • Effect of a selective and potent central nervous system penetrant, neurokinin-3 receptor antagonist (SB-222200), on cisplatin-induced emesis in the ferret
    • King A., and Sanger G.J. Effect of a selective and potent central nervous system penetrant, neurokinin-3 receptor antagonist (SB-222200), on cisplatin-induced emesis in the ferret. Neurosci. Lett. 376 (2005) 5-8
    • (2005) Neurosci. Lett. , vol.376 , pp. 5-8
    • King, A.1    Sanger, G.J.2
  • 34
    • 0033820370 scopus 로고    scopus 로고
    • Neurochemical classification of enteric neurons in the guinea-pig distal colon
    • Lomax A.E.G., and Furness J.B. Neurochemical classification of enteric neurons in the guinea-pig distal colon. Cell Tissue Res. 302 (2000) 59-73
    • (2000) Cell Tissue Res. , vol.302 , pp. 59-73
    • Lomax, A.E.G.1    Furness, J.B.2
  • 35
    • 0030664860 scopus 로고    scopus 로고
    • Cellular pathway mediating tachykinin-evoked secretomotor responses in guinea-pig ileum
    • MacNaughton W., Moore B., and Vanner S. Cellular pathway mediating tachykinin-evoked secretomotor responses in guinea-pig ileum. Am. J. Physiol. 273 (1997) G1127-G1134
    • (1997) Am. J. Physiol. , vol.273
    • MacNaughton, W.1    Moore, B.2    Vanner, S.3
  • 36
    • 0034192260 scopus 로고    scopus 로고
    • The troubled story of tachykinins and neurokinins
    • Maggi C.A. The troubled story of tachykinins and neurokinins. Trends Pharmacol. Sci. 21 (2000) 173-175
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 173-175
    • Maggi, C.A.1
  • 38
    • 0030780796 scopus 로고    scopus 로고
    • Electrophysiological characterisation of tachykinin receptors in the rat nucleus of the solitary tract and dorsal motor nucleus of the vagus in vitro
    • Maubach K.A., and Jones R.S. Electrophysiological characterisation of tachykinin receptors in the rat nucleus of the solitary tract and dorsal motor nucleus of the vagus in vitro. Br. J. Pharmacol. 122 (1997) 1151-1159
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1151-1159
    • Maubach, K.A.1    Jones, R.S.2
  • 39
    • 0032547115 scopus 로고    scopus 로고
    • Comparative effects of non peptide tachykinin receptor antagonists on experimental gut inflammation in rats and guinea-pigs
    • Mazelin L., Theodorou V., More J., Emonds-Alt X., Fioramonti J., and Bueno L. Comparative effects of non peptide tachykinin receptor antagonists on experimental gut inflammation in rats and guinea-pigs. Life Sci. 63 (1998) 293-304
    • (1998) Life Sci. , vol.63 , pp. 293-304
    • Mazelin, L.1    Theodorou, V.2    More, J.3    Emonds-Alt, X.4    Fioramonti, J.5    Bueno, L.6
  • 40
    • 0032568303 scopus 로고    scopus 로고
    • Effects of tachykinin receptor antagonists on the rat jejunal distension pain response
    • McLean P.G., Garcia-Villar R., Fioramonti J., and Bueno L. Effects of tachykinin receptor antagonists on the rat jejunal distension pain response. Eur. J. Pharmacol. 345 (1998) 247-252
    • (1998) Eur. J. Pharmacol. , vol.345 , pp. 247-252
    • McLean, P.G.1    Garcia-Villar, R.2    Fioramonti, J.3    Bueno, L.4
  • 42
    • 0021995138 scopus 로고
    • Significance of slow synaptic potentials for transmission of excitation in guinea-pig myenteric plexus
    • Morita K., and North R.A. Significance of slow synaptic potentials for transmission of excitation in guinea-pig myenteric plexus. Neurosci. 14 (1985) 661-672
    • (1985) Neurosci. , vol.14 , pp. 661-672
    • Morita, K.1    North, R.A.2
  • 43
    • 0033151756 scopus 로고    scopus 로고
    • Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon
    • Neunlist M., Dobreva G., and Schemann M. Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon. J. Physiol. 517.2 (1999) 533-546
    • (1999) J. Physiol. , vol.517 2 , pp. 533-546
    • Neunlist, M.1    Dobreva, G.2    Schemann, M.3
  • 45
    • 0035386848 scopus 로고    scopus 로고
    • Relationship between postsynaptic NK1 receptor distribution and nerve terminals innervating myenteric neurons in the guinea-pig ileum
    • Portbury A.L., Grkovic I., Young H.M., and Furness J.B. Relationship between postsynaptic NK1 receptor distribution and nerve terminals innervating myenteric neurons in the guinea-pig ileum. Anat. Rec. 263 (2001) 248-254
    • (2001) Anat. Rec. , vol.263 , pp. 248-254
    • Portbury, A.L.1    Grkovic, I.2    Young, H.M.3    Furness, J.B.4
  • 46
    • 0033918053 scopus 로고    scopus 로고
    • Role of neurokinin receptors in the behavioral effect of intravesicular antigen infusion in guinea-pig bladder
    • Ruggieri M.R., Filer-Maerten S., Hieble J.P., and Hay D.W. Role of neurokinin receptors in the behavioral effect of intravesicular antigen infusion in guinea-pig bladder. J. Urol. 164 (2000) 197-202
    • (2000) J. Urol. , vol.164 , pp. 197-202
    • Ruggieri, M.R.1    Filer-Maerten, S.2    Hieble, J.P.3    Hay, D.W.4
  • 47
    • 2442476519 scopus 로고    scopus 로고
    • 3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain
    • 3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain. Br. J. Pharmacol. 141 (2004) 1303-1312
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 1303-1312
    • Sanger, G.J.1
  • 49
    • 15144349599 scopus 로고    scopus 로고
    • Nonpeptide tachykinin receptor antagonists .1. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist
    • Sarau H.M., Griswold D.E., Potts W., et al. Nonpeptide tachykinin receptor antagonists .1. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. J. Pharmacol. Exp. Ther. 281 (1997) 1303-1311
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 1303-1311
    • Sarau, H.M.1    Griswold, D.E.2    Potts, W.3
  • 50
    • 0026356035 scopus 로고
    • Effects of tachykinins on myenteric neurones of the guinea-pig gastric corpus: involvement of NK-3 receptors
    • Schemann M., and Kayser H. Effects of tachykinins on myenteric neurones of the guinea-pig gastric corpus: involvement of NK-3 receptors. Pflugers Arch. 419 (1991) 566-571
    • (1991) Pflugers Arch. , vol.419 , pp. 566-571
    • Schemann, M.1    Kayser, H.2
  • 51
    • 0031727610 scopus 로고    scopus 로고
    • NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals
    • Schmid G., Carita F., Bonanno G., and Raiteri M. NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals. Br. J. Pharmacol. 125 (1998) 621-626
    • (1998) Br. J. Pharmacol. , vol.125 , pp. 621-626
    • Schmid, G.1    Carita, F.2    Bonanno, G.3    Raiteri, M.4
  • 52
    • 0036000204 scopus 로고    scopus 로고
    • 1 receptors mediate atropine-resistant net aboral propulsive complexes in porcine ileum
    • 1 receptors mediate atropine-resistant net aboral propulsive complexes in porcine ileum. Scand. J. Gastroenterol. 37 (2002) 531-535
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 531-535
    • Schmidt, P.T.1    Hoist, J.J.2
  • 54
    • 0024998385 scopus 로고
    • Distribution and localisation of neurokinin A-like immunoreactivity and neurokinin B-like immunoreactivity in rat peripheral tissue
    • Tsuchida K., Shigemoto R., Yokota Y., and Nakanishi S. Distribution and localisation of neurokinin A-like immunoreactivity and neurokinin B-like immunoreactivity in rat peripheral tissue. Regul. Pept. 30 (1990) 193-200
    • (1990) Regul. Pept. , vol.30 , pp. 193-200
    • Tsuchida, K.1    Shigemoto, R.2    Yokota, Y.3    Nakanishi, S.4
  • 55
    • 33751009735 scopus 로고    scopus 로고
    • Receptor antagonist talnetant (SB-223412) modulates peristalsis induced by supra-optimal distension pressure in the guinea-pig isolated ileum
    • Tuladhar B.R., Aziz E., and Sanger G.J. Receptor antagonist talnetant (SB-223412) modulates peristalsis induced by supra-optimal distension pressure in the guinea-pig isolated ileum. Gastroenterol. 126 Suppl. 2 (2004) A277
    • (2004) Gastroenterol. , vol.126 , Issue.SUPPL. 2
    • Tuladhar, B.R.1    Aziz, E.2    Sanger, G.J.3
  • 56
    • 0036168146 scopus 로고    scopus 로고
    • Localisation of neurokinin B receptor in mouse gastrointestinal tract
    • Wang H., Zhang Y.-Q., Ding Y.-Q., and Zhang J.-S. Localisation of neurokinin B receptor in mouse gastrointestinal tract. World J. Gastroenterol. 8 (2002) 172-175
    • (2002) World J. Gastroenterol. , vol.8 , pp. 172-175
    • Wang, H.1    Zhang, Y.-Q.2    Ding, Y.-Q.3    Zhang, J.-S.4


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