-
1
-
-
33747892114
-
A concise review of DNA damage checkpoints and repair in mammalian cells
-
doi: 10.1016/j.carrev.2006.02.002
-
Houtgraaf JH, Versmissen J, van der Giessen WJ. A concise review of DNA damage checkpoints and repair in mammalian cells. Cardiovasc Revasc Med (2006) 7(3):165-72. doi: 10.1016/j.carrev.2006.02.002
-
(2006)
Cardiovasc Revasc Med
, vol.7
, Issue.3
, pp. 165-72
-
-
Houtgraaf, J.H.1
Versmissen, J.2
van der Giessen, W.J.3
-
2
-
-
10744226451
-
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361
-
doi:10.1093/jnci/djh005
-
Calabrese CR, Almassy R, Barton S, Batey MA, Calvert AH, Canan-Koch S, et al. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J Natl Cancer Inst (2004) 96(1):56-67. doi:10.1093/jnci/djh005
-
(2004)
J Natl Cancer Inst
, vol.96
, Issue.1
, pp. 56-67
-
-
Calabrese, C.R.1
Almassy, R.2
Barton, S.3
Batey, M.A.4
Calvert, A.H.5
Canan-Koch, S.6
-
3
-
-
59449085305
-
Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors
-
doi:10.1158/1078-0432.CCR-08-1223
-
Plummer R, Jones C, Middleton M, Wilson R, Evans J, Olsen A, et al. Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors. Clin Cancer Res (2008) 14(23):7917-23. doi:10.1158/1078-0432.CCR-08-1223
-
(2008)
Clin Cancer Res
, vol.14
, Issue.23
, pp. 7917-23
-
-
Plummer, R.1
Jones, C.2
Middleton, M.3
Wilson, R.4
Evans, J.5
Olsen, A.6
-
4
-
-
79952281417
-
A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours
-
doi:10.1038/bjc.2011.8
-
Khan OA, Gore M, Lorigan P, Stone J, Greystoke A, Burke W, et al. A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours. Br J Cancer (2011) 104(5):750-5. doi:10.1038/bjc.2011.8
-
(2011)
Br J Cancer
, vol.104
, Issue.5
, pp. 750-5
-
-
Khan, O.A.1
Gore, M.2
Lorigan, P.3
Stone, J.4
Greystoke, A.5
Burke, W.6
-
5
-
-
84863236347
-
A phase I study of veliparib in combination with metronomic cyclophosphamide in adults with refractory solid tumors and lymphomas
-
doi:10.1158/1078-0432.CCR-11-2821
-
Kummar S, Ji J, Morgan R, Lenz HJ, Puhalla SL, Belani CP, et al. A phase I study of veliparib in combination with metronomic cyclophosphamide in adults with refractory solid tumors and lymphomas. Clin Cancer Res (2012) 18(6):1726-34. doi:10.1158/1078-0432.CCR-11-2821
-
(2012)
Clin Cancer Res
, vol.18
, Issue.6
, pp. 1726-34
-
-
Kummar, S.1
Ji, J.2
Morgan, R.3
Lenz, H.J.4
Puhalla, S.L.5
Belani, C.P.6
-
6
-
-
79960359070
-
The poly(ADP-ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy
-
doi:10.1016/j.radonc.2011.05.084
-
Nowsheen S, Bonner JA, Yang ES. The poly(ADP-ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy. Radiother Oncol (2011) 99(3):331-8. doi:10.1016/j.radonc.2011.05.084
-
(2011)
Radiother Oncol
, vol.99
, Issue.3
, pp. 331-8
-
-
Nowsheen, S.1
Bonner, J.A.2
Yang, E.S.3
-
7
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
doi:10.1038/nature03443
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature (2005) 434(7035):913-7. doi:10.1038/nature03443
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-7
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
-
8
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
doi:10.1038/nature03445
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature (2005) 434(7035):917-21. doi:10.1038/nature03445
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-21
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
-
9
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
doi:10.1056/NEJMoa0900212
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med (2009) 361(2):123-34. doi:10.1056/NEJMoa0900212
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-34
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
-
10
-
-
68149161777
-
Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer
-
CRA501. doi:10.1016/S0140-6736(10)60892-6
-
Tutt A, Robson M, Garber JE, Domchek S, Audeh MW, Weitzel JN, et al. Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer. J Clin Oncol (2009) 27(185):CRA501. doi:10.1016/S0140-6736(10)60892-6
-
(2009)
J Clin Oncol
, vol.27
, Issue.185
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.4
Audeh, M.W.5
Weitzel, J.N.6
-
11
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study
-
doi:10.1016/S1470-2045(11)70214-5
-
Gelmon KA, Tischkowitz M, Mackay H, Swenerton K, Robidoux A, Tonkin K, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study. Lancet Oncol (2011) 12(9):852-61. doi:10.1016/S1470-2045(11)70214-5
-
(2011)
Lancet Oncol
, vol.12
, Issue.9
, pp. 852-61
-
-
Gelmon, K.A.1
Tischkowitz, M.2
Mackay, H.3
Swenerton, K.4
Robidoux, A.5
Tonkin, K.6
-
12
-
-
70350243066
-
Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity
-
doi:10.1158/1078-0432.ccr-09-0910.
-
Melisi D, Ossovskaya V, Zhu C, Rosa R, Ling J, Dougherty PM, et al. Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity. Clin Cancer Res (2009) 15(20):6367-77. doi:10.1158/1078-0432.ccr-09-0910.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.20
, pp. 6367-77
-
-
Melisi, D.1
Ossovskaya, V.2
Zhu, C.3
Rosa, R.4
Ling, J.5
Dougherty, P.M.6
-
13
-
-
84866391539
-
HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair
-
doi:10.1158/0008-5472.CAN-12-1287
-
Nowsheen S, Cooper T, Bonner JA, LoBuglio AF, Yang ES. HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair. Cancer Res (2012) 72(18):4796-806. doi:10.1158/0008-5472.CAN-12-1287
-
(2012)
Cancer Res
, vol.72
, Issue.18
, pp. 4796-806
-
-
Nowsheen, S.1
Cooper, T.2
Bonner, J.A.3
LoBuglio, A.F.4
Yang, E.S.5
-
14
-
-
79955968629
-
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
-
doi:10.1016/j.ccr.2011.04.010
-
Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, et al. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell (2011) 19(5):664-78. doi:10.1016/j.ccr.2011.04.010
-
(2011)
Cancer Cell
, vol.19
, Issue.5
, pp. 664-78
-
-
Brenner, J.C.1
Ateeq, B.2
Li, Y.3
Yocum, A.K.4
Cao, Q.5
Asangani, I.A.6
-
15
-
-
84859391984
-
PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma
-
doi:10.1158/0008-5472.CAN-11-3648
-
Brenner JC, Feng FY, Han S, Patel S, Goyal SV, Bou-Maroun LM, et al. PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma. Cancer Res (2012) 72(7):1608-13. doi:10.1158/0008-5472.CAN-11-3648
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1608-13
-
-
Brenner, J.C.1
Feng, F.Y.2
Han, S.3
Patel, S.4
Goyal, S.V.5
Bou-Maroun, L.M.6
-
16
-
-
84870806776
-
Investigation of PARP1 as a therapeutic target in small cell lung cancer
-
doi:10.1371/journal.pone.0056284
-
Byers LA, Nilsson MB, Masrorpour F, Wang J, Diao L, Bhardwaj V, et al. Investigation of PARP1 as a therapeutic target in small cell lung cancer. J Clin Oncol (2012) 30(Suppl):7096. doi:10.1371/journal.pone.0056284
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
, pp. 7096
-
-
Byers, L.A.1
Nilsson, M.B.2
Masrorpour, F.3
Wang, J.4
Diao, L.5
Bhardwaj, V.6
-
17
-
-
84891116356
-
Preclinical study of a PARP inhibitor in neuroblastoma
-
Addioui A, Belounis A, Cournoyer S, Nyalendo C, Brito R-M, Beaunoyer M, et al. Preclinical study of a PARP inhibitor in neuroblastoma. J Clin Oncol (2012) 30(Suppl):9570.
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
, pp. 9570
-
-
Addioui, A.1
Belounis, A.2
Cournoyer, S.3
Nyalendo, C.4
Brito, R.-M.5
Beaunoyer, M.6
-
18
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
doi:10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144(5):646-74. doi:10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-74
-
-
Hanahan, D.1
Weinberg, R.A.2
-
19
-
-
0037043125
-
Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer
-
doi:10.1016/S0304-3835(01)00795-9
-
Gilmore T, Gapuzan ME, Kalaitzidis D, Starczynowski D. Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer. Cancer Lett (2002) 181(1):1-9. doi:10.1016/S0304-3835(01)00795-9
-
(2002)
Cancer Lett
, vol.181
, Issue.1
, pp. 1-9
-
-
Gilmore, T.1
Gapuzan, M.E.2
Kalaitzidis, D.3
Starczynowski, D.4
-
20
-
-
84880869807
-
The complexity of NF-kappaB signaling in inflammation and cancer
-
doi:10.1186/1476-4598-12-86
-
Hoesel B, Schmid JA. The complexity of NF-kappaB signaling in inflammation and cancer. Mol Cancer (2013) 12:86. doi:10.1186/1476-4598-12-86
-
(2013)
Mol Cancer
, vol.12
, pp. 86
-
-
Hoesel, B.1
Schmid, J.A.2
-
21
-
-
0242496900
-
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1
-
doi:10.1074/jbc.M307957200
-
Hassa PO, Buerki C, Lombardi C, Imhof R, Hottiger MO. Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. J Biol Chem (2003) 278(46):45145-53. doi:10.1074/jbc.M307957200
-
(2003)
J Biol Chem
, vol.278
, Issue.46
, pp. 45145-53
-
-
Hassa, P.O.1
Buerki, C.2
Lombardi, C.3
Imhof, R.4
Hottiger, M.O.5
-
22
-
-
28844493947
-
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription
-
doi:10.1074/jbc.M507553200
-
Hassa PO, Haenni SS, Buerki C, Meier NI, Lane WS, Owen H, et al. Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. J Biol Chem (2005) 280(49):40450-64. doi:10.1074/jbc.M507553200
-
(2005)
J Biol Chem
, vol.280
, Issue.49
, pp. 40450-64
-
-
Hassa, P.O.1
Haenni, S.S.2
Buerki, C.3
Meier, N.I.4
Lane, W.S.5
Owen, H.6
-
23
-
-
70350548179
-
Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function
-
doi:10.1096/fj.09-137695
-
Messner S, Schuermann D, Altmeyer M, Kassner I, Schmidt D, Schar P, et al. Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB J (2009) 23(11):3978-89. doi:10.1096/fj.09-137695
-
(2009)
FASEB J
, vol.23
, Issue.11
, pp. 3978-89
-
-
Messner, S.1
Schuermann, D.2
Altmeyer, M.3
Kassner, I.4
Schmidt, D.5
Schar, P.6
-
24
-
-
70449102637
-
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation
-
doi:10.1016/j.molcel.2009.09.032
-
Stilmann M, Hinz M, Arslan SC, Zimmer A, Schreiber V, Scheidereit C. A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell (2009) 36(3):365-78. doi:10.1016/j.molcel.2009.09.032
-
(2009)
Mol Cell
, vol.36
, Issue.3
, pp. 365-78
-
-
Stilmann, M.1
Hinz, M.2
Arslan, S.C.3
Zimmer, A.4
Schreiber, V.5
Scheidereit, C.6
-
25
-
-
0035861675
-
The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1
-
doi:10.1074/jbc.M104666200
-
Chang WJ, Alvarez-Gonzalez R. The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1. J Biol Chem (2001) 276(50):47664-70. doi:10.1074/jbc.M104666200
-
(2001)
J Biol Chem
, vol.276
, Issue.50
, pp. 47664-70
-
-
Chang, W.J.1
Alvarez-Gonzalez, R.2
-
26
-
-
77956402804
-
Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation
-
doi:10.4049/jimmunol.1000646
-
Zerfaoui M, Errami Y, Naura AS, Suzuki Y, Kim H, Ju J, et al. Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation. J Immunol (2010) 185(3):1894-902. doi:10.4049/jimmunol.1000646
-
(2010)
J Immunol
, vol.185
, Issue.3
, pp. 1894-902
-
-
Zerfaoui, M.1
Errami, Y.2
Naura, A.S.3
Suzuki, Y.4
Kim, H.5
Ju, J.6
-
27
-
-
60149100173
-
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance
-
doi:10.1038/onc.2008.439
-
Veuger SJ, Hunter JE, Durkacz BW. Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. Oncogene (2009) 28(6):832-42. doi:10.1038/onc.2008.439
-
(2009)
Oncogene
, vol.28
, Issue.6
, pp. 832-42
-
-
Veuger, S.J.1
Hunter, J.E.2
Durkacz, B.W.3
-
28
-
-
33748070489
-
Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice
-
doi:10.1038/sj.bjp.0706837
-
Haddad M, Rhinn H, Bloquel C, Coqueran B, Szabo C, Plotkine M, et al. Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice. Br J Pharmacol (2006) 149(1):23-30. doi:10.1038/sj.bjp.0706837
-
(2006)
Br J Pharmacol
, vol.149
, Issue.1
, pp. 23-30
-
-
Haddad, M.1
Rhinn, H.2
Bloquel, C.3
Coqueran, B.4
Szabo, C.5
Plotkine, M.6
-
29
-
-
0033825626
-
Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis
-
Jijon HB, Churchill T, Malfair D, Wessler A, Jewell LD, Parsons HG, et al. Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis. Am J Physiol Gastrointest Liver Physiol (2000) 279(3):G641-51.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
, Issue.3
-
-
Jijon, H.B.1
Churchill, T.2
Malfair, D.3
Wessler, A.4
Jewell, L.D.5
Parsons, H.G.6
-
30
-
-
59649084921
-
Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia
-
doi:10.1183/09031936.00089008
-
Naura AS, Datta R, Hans CP, Zerfaoui M, Rezk BM, Errami Y, et al. Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia. Eur Respir J (2009) 33(2):252-62. doi:10.1183/09031936.00089008
-
(2009)
Eur Respir J
, vol.33
, Issue.2
, pp. 252-62
-
-
Naura, A.S.1
Datta, R.2
Hans, C.P.3
Zerfaoui, M.4
Rezk, B.M.5
Errami, Y.6
-
31
-
-
40149095477
-
Effects of poly(ADP-ribose) polymerase inhibition in bladder damage caused by cyclophosphamide in rats
-
doi:10.3181/0706-RM-151
-
Korkmaz A, Kurt B, Yildirim I, Basal S, Topal T, Sadir S, et al. Effects of poly(ADP-ribose) polymerase inhibition in bladder damage caused by cyclophosphamide in rats. Exp Biol Med (Maywood) (2008) 233(3):338-43. doi:10.3181/0706-RM-151
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, Issue.3
, pp. 338-43
-
-
Korkmaz, A.1
Kurt, B.2
Yildirim, I.3
Basal, S.4
Topal, T.5
Sadir, S.6
-
32
-
-
3442890964
-
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia
-
doi:10.1038/sj.onc.1207696
-
Martin-Oliva D, O'Valle F, Munoz-Gamez JA, Valenzuela MT, Nunez MI, Aguilar M, et al. Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia. Oncogene (2004) 23(31):5275-83. doi:10.1038/sj.onc.1207696
-
(2004)
Oncogene
, vol.23
, Issue.31
, pp. 5275-83
-
-
Martin-Oliva, D.1
O'Valle, F.2
Munoz-Gamez, J.A.3
Valenzuela, M.T.4
Nunez, M.I.5
Aguilar, M.6
-
33
-
-
0035849720
-
Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
-
doi:10.1038/sj.onc.1204535
-
Huang S, Pettaway CA, Uehara H, Bucana CD, Fidler IJ. Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene (2001) 20(31):4188-97. doi:10.1038/sj.onc.1204535
-
(2001)
Oncogene
, vol.20
, Issue.31
, pp. 4188-97
-
-
Huang, S.1
Pettaway, C.A.2
Uehara, H.3
Bucana, C.D.4
Fidler, I.J.5
-
34
-
-
79959635610
-
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
-
doi:10.1101/gad.625811
-
Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, et al. Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS). Genes Dev (2011) 25(12):1245-61. doi:10.1101/gad.625811
-
(2011)
Genes Dev
, vol.25
, Issue.12
, pp. 1245-61
-
-
Ohanna, M.1
Giuliano, S.2
Bonet, C.3
Imbert, V.4
Hofman, V.5
Zangari, J.6
-
35
-
-
35648970074
-
IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
-
doi:10.1073/pnas.0706728104
-
Cao Y, Luo JL, Karin M. IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. Proc Natl Acad Sci U S A (2007) 104(40):15852-7. doi:10.1073/pnas.0706728104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.40
, pp. 15852-7
-
-
Cao, Y.1
Luo, J.L.2
Karin, M.3
-
36
-
-
29844443023
-
Physiological ageing: role of p53 and PARP-1 tumor suppressors in the regulation of terminal senescence
-
Wesierska-Gadek J, Ranftler C, Schmid G. Physiological ageing: role of p53 and PARP-1 tumor suppressors in the regulation of terminal senescence. J Physiol Pharmacol (2005) 56(Suppl 2):77-88.
-
(2005)
J Physiol Pharmacol
, vol.56
, Issue.SUPPL. 2
, pp. 77-88
-
-
Wesierska-Gadek, J.1
Ranftler, C.2
Schmid, G.3
-
37
-
-
84883469199
-
PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy
-
doi:10.1158/1078-0432.CCR-13-0516
-
Yuan K, Sun Y, Zhou T, McDonald JM, Chen Y. PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. Clin Cancer Res (2013) 19(17):4750-9. doi:10.1158/1078-0432.CCR-13-0516
-
(2013)
Clin Cancer Res
, vol.19
, Issue.17
, pp. 4750-9
-
-
Yuan, K.1
Sun, Y.2
Zhou, T.3
McDonald, J.M.4
Chen, Y.5
-
38
-
-
79953840957
-
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)
-
doi:10.1126/scisignal.2000902
-
Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, et al. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal (2011) 4(167):ra20. doi:10.1126/scisignal.2000902
-
(2011)
Sci Signal
, vol.4
, Issue.167
-
-
Wang, Y.1
Kim, N.S.2
Haince, J.F.3
Kang, H.C.4
David, K.K.5
Andrabi, S.A.6
-
39
-
-
0036022402
-
Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update
-
doi:10.1023/A:1016119328968
-
Soldani C, Scovassi AI. Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis (2002) 7(4):321-8. doi:10.1023/A:1016119328968
-
(2002)
Apoptosis
, vol.7
, Issue.4
, pp. 321-8
-
-
Soldani, C.1
Scovassi, A.I.2
-
40
-
-
4143092815
-
Modulation of poly(ADP-ribosylation) in apoptotic cells
-
doi:10.1016/j.bcp.2004.04.023
-
Ivana Scovassi A, Diederich M. Modulation of poly(ADP-ribosylation) in apoptotic cells. Biochem Pharmacol (2004) 68(6):1041-7. doi:10.1016/j.bcp.2004.04.023
-
(2004)
Biochem Pharmacol
, vol.68
, Issue.6
, pp. 1041-7
-
-
Ivana Scovassi, A.1
Diederich, M.2
-
41
-
-
0032577703
-
Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis
-
doi:10.1074/jbc.273.22.13703
-
Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, Boulares AH, Smulson ME. Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis. J Biol Chem (1998) 273(22):13703-12. doi:10.1074/jbc.273.22.13703
-
(1998)
J Biol Chem
, vol.273
, Issue.22
, pp. 13703-12
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Iyer, S.3
Boulares, A.H.4
Smulson, M.E.5
-
42
-
-
0037087592
-
BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity
-
doi:10.1016/S0006-2952(01)00935-2
-
Racz I, Tory K, Gallyas F Jr, Berente Z, Osz E, Jaszlits L, et al. BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. Biochem Pharmacol (2002) 63(6):1099-111. doi:10.1016/S0006-2952(01)00935-2
-
(2002)
Biochem Pharmacol
, vol.63
, Issue.6
, pp. 1099-111
-
-
Racz, I.1
Tory, K.2
Gallyas Jr., F.3
Berente, Z.4
Osz, E.5
Jaszlits, L.6
-
43
-
-
84867559728
-
Potential role of poly(ADP-ribose) polymerase (PARP) activation in methotrexate-induced nephrotoxicity and tubular apoptosis
-
doi:10.1177/1091581812457430
-
Dalaklioglu S, Sahin P, Ordueri EG, Celik-Ozenci C, Tasatargil A. Potential role of poly(ADP-ribose) polymerase (PARP) activation in methotrexate-induced nephrotoxicity and tubular apoptosis. Int J Toxicol (2012) 31(5):430-40. doi:10.1177/1091581812457430
-
(2012)
Int J Toxicol
, vol.31
, Issue.5
, pp. 430-40
-
-
Dalaklioglu, S.1
Sahin, P.2
Ordueri, E.G.3
Celik-Ozenci, C.4
Tasatargil, A.5
-
44
-
-
0035872409
-
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice
-
Chen N, Nomura M, She QB, Ma WY, Bode AM, Wang L, et al. Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice. Cancer Res (2001) 61(10):3908-12.
-
(2001)
Cancer Res
, vol.61
, Issue.10
, pp. 3908-12
-
-
Chen, N.1
Nomura, M.2
She, Q.B.3
Ma, W.Y.4
Bode, A.M.5
Wang, L.6
-
45
-
-
1642486367
-
Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling
-
doi:10.1111/j.1349-7006.2004.tb03200.x
-
Yang Y, Ikezoe T, Saito T, Kobayashi M, Koeffler HP, Taguchi H. Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. Cancer Sci (2004) 95(2):176-80. doi:10.1111/j.1349-7006.2004.tb03200.x
-
(2004)
Cancer Sci
, vol.95
, Issue.2
, pp. 176-80
-
-
Yang, Y.1
Ikezoe, T.2
Saito, T.3
Kobayashi, M.4
Koeffler, H.P.5
Taguchi, H.6
-
46
-
-
78650174952
-
Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation
-
doi:10.1016/j.freeradbiomed.2010.09.026
-
Racz B, Hanto K, Tapodi A, Solti I, Kalman N, Jakus P, et al. Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation. Free Radic Biol Med (2010) 49(12):1978-88. doi:10.1016/j.freeradbiomed.2010.09.026
-
(2010)
Free Radic Biol Med
, vol.49
, Issue.12
, pp. 1978-88
-
-
Racz, B.1
Hanto, K.2
Tapodi, A.3
Solti, I.4
Kalman, N.5
Jakus, P.6
-
47
-
-
62749143454
-
PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol
-
doi:10.1016/j.bcp.2009.01.008
-
Szanto A, Hellebrand EE, Bognar Z, Tucsek Z, Szabo A, Gallyas F Jr, et al. PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol. Biochem Pharmacol (2009) 77(8):1348-57. doi:10.1016/j.bcp.2009.01.008
-
(2009)
Biochem Pharmacol
, vol.77
, Issue.8
, pp. 1348-57
-
-
Szanto, A.1
Hellebrand, E.E.2
Bognar, Z.3
Tucsek, Z.4
Szabo, A.5
Gallyas Jr., F.6
-
48
-
-
34247383146
-
c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation
-
doi:10.1038/sj.cdd.4402088
-
Zhang S, Lin Y, Kim YS, Hande MP, Liu ZG, Shen HM. c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation. Cell Death Differ (2007) 14(5):1001-10. doi:10.1038/sj.cdd.4402088
-
(2007)
Cell Death Differ
, vol.14
, Issue.5
, pp. 1001-10
-
-
Zhang, S.1
Lin, Y.2
Kim, Y.S.3
Hande, M.P.4
Liu, Z.G.5
Shen, H.M.6
-
49
-
-
84886727189
-
Poly(ADP-ribose) signaling in cell death
-
doi:10.1016/j.mam.2013.01.007
-
Virag L, Robaszkiewicz A, Vargas JM, Javier Oliver F. Poly(ADP-ribose) signaling in cell death. Mol Aspects Med (2013) 34(6):1153-67. doi:10.1016/j.mam.2013.01.007
-
(2013)
Mol Aspects Med
, vol.34
, Issue.6
, pp. 1153-67
-
-
Virag, L.1
Robaszkiewicz, A.2
Vargas, J.M.3
Javier Oliver, F.4
-
50
-
-
84868118383
-
PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent
-
doi:10.1371/journal.pone.0047978
-
Ethier C, Tardif M, Arul L, Poirier GG. PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent. PLoS One (2012) 7(10):e47978. doi:10.1371/journal.pone.0047978
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Ethier, C.1
Tardif, M.2
Arul, L.3
Poirier, G.G.4
-
51
-
-
80052035265
-
PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1
-
doi:10.1016/j.bbrc.2011.07.107
-
Wang S, Wang H, Davis BC, Liang J, Cui R, Chen SJ, et al. PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1. Biochem Biophys Res Commun (2011) 412(2):379-84. doi:10.1016/j.bbrc.2011.07.107
-
(2011)
Biochem Biophys Res Commun
, vol.412
, Issue.2
, pp. 379-84
-
-
Wang, S.1
Wang, H.2
Davis, B.C.3
Liang, J.4
Cui, R.5
Chen, S.J.6
-
52
-
-
84860242440
-
BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases
-
doi:10.1007/s11010-012-1252-8
-
Sarszegi Z, Bognar E, Gaszner B, Konyi A, Gallyas F Jr, Sumegi B, et al. BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases. Mol Cell Biochem (2012) 365(1-2):129-37. doi:10.1007/s11010-012-1252-8
-
(2012)
Mol Cell Biochem
, vol.365
, Issue.1-2
, pp. 129-37
-
-
Sarszegi, Z.1
Bognar, E.2
Gaszner, B.3
Konyi, A.4
Gallyas Jr., F.5
Sumegi, B.6
-
53
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
doi:10.1002/1097-4644(20001201)79:3<355::AID-JCB20>3.0.CO;2-0
-
Boucher MJ, Morisset J, Vachon PH, Reed JC, Laine J, Rivard N. MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem (2000) 79(3):355-69. doi:10.1002/1097-4644(20001201)79:3<355::AID-JCB20>3.0.CO;2-0
-
(2000)
J Cell Biochem
, vol.79
, Issue.3
, pp. 355-69
-
-
Boucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Laine, J.5
Rivard, N.6
-
54
-
-
84858658094
-
Blocking epidermal growth factor receptor activation by 3,3'-diindolylmethane suppresses ovarian tumor growth in vitro and in vivo
-
doi:10.1124/jpet.111.188706
-
Kandala PK, Wright SE, Srivastava SK. Blocking epidermal growth factor receptor activation by 3,3'-diindolylmethane suppresses ovarian tumor growth in vitro and in vivo. J Pharmacol Exp Ther (2012) 341(1):24-32. doi:10.1124/jpet.111.188706
-
(2012)
J Pharmacol Exp Ther
, vol.341
, Issue.1
, pp. 24-32
-
-
Kandala, P.K.1
Wright, S.E.2
Srivastava, S.K.3
-
55
-
-
84455208086
-
Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression
-
doi:10.1016/j.bcp.2011.11.008
-
Kim HS, Kim MJ, Kim EJ, Yang Y, Lee MS, Lim JS. Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. Biochem Pharmacol (2012) 83(3):385-94. doi:10.1016/j.bcp.2011.11.008
-
(2012)
Biochem Pharmacol
, vol.83
, Issue.3
, pp. 385-94
-
-
Kim, H.S.1
Kim, M.J.2
Kim, E.J.3
Yang, Y.4
Lee, M.S.5
Lim, J.S.6
-
56
-
-
83255162009
-
Targeting the extracellular signal-regulated kinase pathway in cancer therapy
-
doi:10.1248/bpb.34.1781
-
Kohno M, Tanimura S, Ozaki K. Targeting the extracellular signal-regulated kinase pathway in cancer therapy. Biol Pharm Bull (2011) 34(12):1781-4. doi:10.1248/bpb.34.1781
-
(2011)
Biol Pharm Bull
, vol.34
, Issue.12
, pp. 1781-4
-
-
Kohno, M.1
Tanimura, S.2
Ozaki, K.3
-
57
-
-
33846362869
-
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation
-
doi:10.1016/j.molcel.2006.12.012
-
Cohen-Armon M, Visochek L, Rozensal D, Kalal A, Geistrikh I, Klein R, et al. DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Mol Cell (2007) 25(2):297-308. doi:10.1016/j.molcel.2006.12.012
-
(2007)
Mol Cell
, vol.25
, Issue.2
, pp. 297-308
-
-
Cohen-Armon, M.1
Visochek, L.2
Rozensal, D.3
Kalal, A.4
Geistrikh, I.5
Klein, R.6
-
58
-
-
46749119301
-
Inhibition of angiogenesis by the poly(ADP-ribose) polymerase inhibitor PJ-34
-
Pyriochou A, Olah G, Deitch EA, Szabo C, Papapetropoulos A. Inhibition of angiogenesis by the poly(ADP-ribose) polymerase inhibitor PJ-34. Int J Mol Med (2008) 22(1):113-8.
-
(2008)
Int J Mol Med
, vol.22
, Issue.1
, pp. 113-8
-
-
Pyriochou, A.1
Olah, G.2
Deitch, E.A.3
Szabo, C.4
Papapetropoulos, A.5
-
59
-
-
64549160302
-
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells
-
doi:10.3892/ijo_00000213
-
Lacal PM, Tentori L, Muzi A, Ruffini F, Dorio AS, Xu W, et al. Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells. Int J Oncol (2009) 34(3):861-72. doi:10.3892/ijo_00000213
-
(2009)
Int J Oncol
, vol.34
, Issue.3
, pp. 861-72
-
-
Lacal, P.M.1
Tentori, L.2
Muzi, A.3
Ruffini, F.4
Dorio, A.S.5
Xu, W.6
-
60
-
-
44449115048
-
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity
-
doi:10.1016/j.ejca.2008.03.019
-
Tentori L, Muzi A, Dorio AS, Bultrini S, Mazzon E, Lacal PM, et al. Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity. Eur J Cancer (2008) 44(9):1302-14. doi:10.1016/j.ejca.2008.03.019
-
(2008)
Eur J Cancer
, vol.44
, Issue.9
, pp. 1302-14
-
-
Tentori, L.1
Muzi, A.2
Dorio, A.S.3
Bultrini, S.4
Mazzon, E.5
Lacal, P.M.6
-
61
-
-
33745288540
-
Inhibition of poly(ADP-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis
-
doi:10.1158/0008-5472.CAN-05-3050
-
Martin-Oliva D, Aguilar-Quesada R, O'Valle F, Munoz-Gamez JA, Martinez-Romero R, Garcia Del Moral R, et al. Inhibition of poly(ADP-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis. Cancer Res (2006) 66(11):5744-56. doi:10.1158/0008-5472.CAN-05-3050
-
(2006)
Cancer Res
, vol.66
, Issue.11
, pp. 5744-56
-
-
Martin-Oliva, D.1
Aguilar-Quesada, R.2
O'Valle, F.3
Munoz-Gamez, J.A.4
Martinez-Romero, R.5
Garcia Del Moral, R.6
-
62
-
-
33750046338
-
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis
-
doi:10.1016/j.bbrc.2006.09.160
-
Rajesh M, Mukhopadhyay P, Godlewski G, Batkai S, Hasko G, Liaudet L, et al. Poly(ADP-ribose)polymerase inhibition decreases angiogenesis. Biochem Biophys Res Commun (2006) 350(4):1056-62. doi:10.1016/j.bbrc.2006.09.160
-
(2006)
Biochem Biophys Res Commun
, vol.350
, Issue.4
, pp. 1056-62
-
-
Rajesh, M.1
Mukhopadhyay, P.2
Godlewski, G.3
Batkai, S.4
Hasko, G.5
Liaudet, L.6
-
63
-
-
84879677739
-
PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation
-
doi:10.1371/journal.pgen.1003531
-
Rodriguez MI, Peralta-Leal A, O'Valle F, Rodriguez-Vargas JM, Gonzalez-Flores A, Majuelos-Melguizo J, et al. PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. PLoS Genet (2013) 9(6):e1003531. doi:10.1371/journal.pgen.1003531
-
(2013)
PLoS Genet
, vol.9
, Issue.6
-
-
Rodriguez, M.I.1
Peralta-Leal, A.2
O'Valle, F.3
Rodriguez-Vargas, J.M.4
Gonzalez-Flores, A.5
Majuelos-Melguizo, J.6
-
64
-
-
1342326790
-
An investigation of the MEK/ERK inhibitor U0126 in acute myeloid leukemia
-
doi:10.1196/annals.1299.013
-
Kerr AHJ, James JA, Smith MA, Willson C, Court EL, Smith JG. An investigation of the MEK/ERK inhibitor U0126 in acute myeloid leukemia. Ann N Y Acad Sci (2003) 1010(1):86-9. doi:10.1196/annals.1299.013
-
(2003)
Ann N Y Acad Sci
, vol.1010
, Issue.1
, pp. 86-9
-
-
Kerr, A.H.J.1
James, J.A.2
Smith, M.A.3
Willson, C.4
Court, E.L.5
Smith, J.G.6
-
65
-
-
33947401129
-
Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor
-
doi:10.1158/1078-0432.CCR-06-1150
-
Yeh TC, Marsh V, Bernat BA, Ballard J, Colwell H, Evans RJ, et al. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor. Clin Cancer Res (2007) 13(5):1576-83. doi:10.1158/1078-0432.CCR-06-1150
-
(2007)
Clin Cancer Res
, vol.13
, Issue.5
, pp. 1576-83
-
-
Yeh, T.C.1
Marsh, V.2
Bernat, B.A.3
Ballard, J.4
Colwell, H.5
Evans, R.J.6
-
66
-
-
34548844157
-
Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis
-
doi:10.1182/blood-2007-03-081240
-
Tai YT, Fulciniti M, Hideshima T, Song W, Leiba M, Li XF, et al. Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis. Blood (2007) 110(5):1656-63. doi:10.1182/blood-2007-03-081240
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1656-63
-
-
Tai, Y.T.1
Fulciniti, M.2
Hideshima, T.3
Song, W.4
Leiba, M.5
Li, X.F.6
-
67
-
-
84880254869
-
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors
-
doi:10.1158/2159-8290.CD-13-0070
-
Morris EJ, Jha S, Restaino CR, Dayananth P, Zhu H, Cooper A, et al. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors. Cancer Discov (2013) 3(7):742-50. doi:10.1158/2159-8290.CD-13-0070
-
(2013)
Cancer Discov
, vol.3
, Issue.7
, pp. 742-50
-
-
Morris, E.J.1
Jha, S.2
Restaino, C.R.3
Dayananth, P.4
Zhu, H.5
Cooper, A.6
-
68
-
-
17144375950
-
ARRY-142886, a potent and selective MEK inhibitor: III) efficacy in murine xenograft models correlates with decreased ERK phosphorylation
-
Lee P, Wallace E, Yeh T, Poch G, Litwiler K, Pheneger T, et al. ARRY-142886, a potent and selective MEK inhibitor: III) efficacy in murine xenograft models correlates with decreased ERK phosphorylation. Proc Am Assoc Cancer Res (2004) 45:3890.
-
(2004)
Proc Am Assoc Cancer Res
, vol.45
, pp. 3890
-
-
Lee, P.1
Wallace, E.2
Yeh, T.3
Poch, G.4
Litwiler, K.5
Pheneger, T.6
-
69
-
-
10344234720
-
Poly(ADP-ribose) is required for spindle assembly and structure
-
doi:10.1038/nature03061
-
Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature (2004) 432(7017):645-9. doi:10.1038/nature03061
-
(2004)
Nature
, vol.432
, Issue.7017
, pp. 645-9
-
-
Chang, P.1
Jacobson, M.K.2
Mitchison, T.J.3
-
70
-
-
0037178870
-
Centromere proteins cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated
-
doi:10.1074/jbc.M200620200
-
Saxena A, Saffery R, Wong LH, Kalitsis P, Choo KH. Centromere proteins cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated. J Biol Chem (2002) 277(30):26921-6. doi:10.1074/jbc.M200620200
-
(2002)
J Biol Chem
, vol.277
, Issue.30
, pp. 26921-6
-
-
Saxena, A.1
Saffery, R.2
Wong, L.H.3
Kalitsis, P.4
Choo, K.H.5
-
71
-
-
0037379179
-
Involvement of poly(ADP-ribose) polymerase 1 and poly(ADP-ribosyl)ation in regulation of centrosome function
-
doi:10.1128/MCB.23.7.2451-2462.2003
-
Kanai M, Tong WM, Sugihara E, Wang ZQ, Fukasawa K, Miwa M. Involvement of poly(ADP-ribose) polymerase 1 and poly(ADP-ribosyl)ation in regulation of centrosome function. Mol Cell Biol (2003) 23(7):2451-62. doi:10.1128/MCB.23.7.2451-2462.2003
-
(2003)
Mol Cell Biol
, vol.23
, Issue.7
, pp. 2451-62
-
-
Kanai, M.1
Tong, W.M.2
Sugihara, E.3
Wang, Z.Q.4
Fukasawa, K.5
Miwa, M.6
-
72
-
-
67649280395
-
Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes
-
doi:10.1016/j.ydbio.2009.05.550
-
Yang F, Baumann C, De La Fuente R. Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes. Dev Biol (2009) 331(2):326-38. doi:10.1016/j.ydbio.2009.05.550
-
(2009)
Dev Biol
, vol.331
, Issue.2
, pp. 326-38
-
-
Yang, F.1
Baumann, C.2
De La Fuente, R.3
-
73
-
-
16544373283
-
Defective control of mitotic and post-mitotic checkpoints in poly(ADP-ribose) polymerase-1(-/-) fibroblasts after mitotic spindle disruption
-
doi:10.4161/cc.3.3.670
-
Halappanavar SS, Shah GM. Defective control of mitotic and post-mitotic checkpoints in poly(ADP-ribose) polymerase-1(-/-) fibroblasts after mitotic spindle disruption. Cell Cycle (2004) 3(3):335-42. doi:10.4161/cc.3.3.670
-
(2004)
Cell Cycle
, vol.3
, Issue.3
, pp. 335-42
-
-
Halappanavar, S.S.1
Shah, G.M.2
-
74
-
-
34249948702
-
Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice
-
doi:10.1038/sj.onc.1210156
-
Tong WM, Yang YG, Cao WH, Galendo D, Frappart L, Shen Y, et al. Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice. Oncogene (2007) 26(26):3857-67. doi:10.1038/sj.onc.1210156
-
(2007)
Oncogene
, vol.26
, Issue.26
, pp. 3857-67
-
-
Tong, W.M.1
Yang, Y.G.2
Cao, W.H.3
Galendo, D.4
Frappart, L.5
Shen, Y.6
-
75
-
-
84859766576
-
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation
-
doi:10.1074/jbc.M111.321828
-
Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, et al. CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation. J Biol Chem (2012) 287(16):12975-84. doi:10.1074/jbc.M111.321828
-
(2012)
J Biol Chem
, vol.287
, Issue.16
, pp. 12975-84
-
-
Kashima, L.1
Idogawa, M.2
Mita, H.3
Shitashige, M.4
Yamada, T.5
Ogi, K.6
-
76
-
-
33847784252
-
Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells
-
doi:10.1186/1471-2164-8-41
-
Ogino H, Nozaki T, Gunji A, Maeda M, Suzuki H, Ohta T, et al. Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells. BMC Genomics (2007) 8:41. doi:10.1186/1471-2164-8-41
-
(2007)
BMC Genomics
, vol.8
, pp. 41
-
-
Ogino, H.1
Nozaki, T.2
Gunji, A.3
Maeda, M.4
Suzuki, H.5
Ohta, T.6
-
77
-
-
73449100129
-
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
-
doi:10.1002/hep.23249
-
Quiles-Perez R, Munoz-Gamez JA, Ruiz-Extremera A, O'Valle F, Sanjuan-Nunez L, Martin-Alvarez AB, et al. Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology (2010) 51(1):255-66. doi:10.1002/hep.23249
-
(2010)
Hepatology
, vol.51
, Issue.1
, pp. 255-66
-
-
Quiles-Perez, R.1
Munoz-Gamez, J.A.2
Ruiz-Extremera, A.3
O'Valle, F.4
Sanjuan-Nunez, L.5
Martin-Alvarez, A.B.6
-
78
-
-
79955012081
-
Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin
-
doi:10.1073/pnas.1019644108
-
Kotova E, Lodhi N, Jarnik M, Pinnola AD, Ji Y, Tulin AV. Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin. Proc Natl Acad Sci U S A (2011) 108(15):6205-10. doi:10.1073/pnas.1019644108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.15
, pp. 6205-10
-
-
Kotova, E.1
Lodhi, N.2
Jarnik, M.3
Pinnola, A.D.4
Ji, Y.5
Tulin, A.V.6
-
79
-
-
10944227347
-
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
-
doi:10.1016/j.cell.2004.11.002
-
Kim MY, Mauro S, Gevry N, Lis JT, Kraus WL. NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell (2004) 119(6):803-14. doi:10.1016/j.cell.2004.11.002
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 803-14
-
-
Kim, M.Y.1
Mauro, S.2
Gevry, N.3
Lis, J.T.4
Kraus, W.L.5
-
80
-
-
77954222814
-
Chromatin regulation by Brg1 underlies heart muscle development and disease
-
doi:10.1038/nature09130
-
Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, et al. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature (2010) 466(7302):62-7. doi:10.1038/nature09130
-
(2010)
Nature
, vol.466
, Issue.7302
, pp. 62-7
-
-
Hang, C.T.1
Yang, J.2
Han, P.3
Cheng, H.L.4
Shang, C.5
Ashley, E.6
-
81
-
-
2942703171
-
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure
-
doi:10.1073/pnas.79.11.3423
-
Poirier GG, de Murcia G, Jongstra-Bilen J, Niedergang C, Mandel P. Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure. Proc Natl Acad Sci U S A (1982) 79(11):3423-7. doi:10.1073/pnas.79.11.3423
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, Issue.11
, pp. 3423-7
-
-
Poirier, G.G.1
de Murcia, G.2
Jongstra-Bilen, J.3
Niedergang, C.4
Mandel, P.5
-
82
-
-
77956526559
-
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway
-
doi:10.1016/j.molcel.2010.08.014
-
Krishnakumar R, Kraus WL. PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. Mol Cell (2010) 39(5):736-49. doi:10.1016/j.molcel.2010.08.014
-
(2010)
Mol Cell
, vol.39
, Issue.5
, pp. 736-49
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
83
-
-
0038682011
-
PARP goes transcription
-
doi:10.1016/S0092-8674(03)00433-1
-
Kraus WL, Lis JT. PARP goes transcription. Cell (2003) 113(6):677-83. doi:10.1016/S0092-8674(03)00433-1
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 677-83
-
-
Kraus, W.L.1
Lis, J.T.2
-
84
-
-
71749119589
-
Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells
-
doi:10.1074/jbc.M109.023879
-
Frizzell KM, Gamble MJ, Berrocal JG, Zhang T, Krishnakumar R, Cen Y, et al. Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells. J Biol Chem (2009) 284(49):33926-38. doi:10.1074/jbc.M109.023879
-
(2009)
J Biol Chem
, vol.284
, Issue.49
, pp. 33926-38
-
-
Frizzell, K.M.1
Gamble, M.J.2
Berrocal, J.G.3
Zhang, T.4
Krishnakumar, R.5
Cen, Y.6
-
85
-
-
12444253985
-
Modulation of DNMT1 activity by ADP-ribose polymers
-
doi:10.1038/sj.onc.1208005
-
Reale A, Matteis GD, Galleazzi G, Zampieri M, Caiafa P. Modulation of DNMT1 activity by ADP-ribose polymers. Oncogene (2005) 24(1):13-9. doi:10.1038/sj.onc.1208005
-
(2005)
Oncogene
, vol.24
, Issue.1
, pp. 13-9
-
-
Reale, A.1
Matteis, G.D.2
Galleazzi, G.3
Zampieri, M.4
Caiafa, P.5
-
86
-
-
6944231017
-
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation
-
doi:10.1038/ng1426
-
Yu W, Ginjala V, Pant V, Chernukhin I, Whitehead J, Docquier F, et al. Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet (2004) 36(10):1105-10. doi:10.1038/ng1426
-
(2004)
Nat Genet
, vol.36
, Issue.10
, pp. 1105-10
-
-
Yu, W.1
Ginjala, V.2
Pant, V.3
Chernukhin, I.4
Whitehead, J.5
Docquier, F.6
-
87
-
-
84884840336
-
Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila
-
doi:10.1016/j.cell.2013.08.052
-
Ong CT, Van Bortle K, Ramos E, Corces VG. Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila. Cell (2013) 155(1):148-59. doi:10.1016/j.cell.2013.08.052
-
(2013)
Cell
, vol.155
, Issue.1
, pp. 148-59
-
-
Ong, C.T.1
Van Bortle, K.2
Ramos, E.3
Corces, V.G.4
-
88
-
-
65549159993
-
Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary
-
doi:10.1016/j.molcel.2009.04.001
-
Witcher M, Emerson BM. Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary. Mol Cell (2009) 34(3):271-84. doi:10.1016/j.molcel.2009.04.001
-
(2009)
Mol Cell
, vol.34
, Issue.3
, pp. 271-84
-
-
Witcher, M.1
Emerson, B.M.2
-
89
-
-
76749171311
-
Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation
-
doi:10.1128/MCB.00827-09
-
Farrar D, Rai S, Chernukhin I, Jagodic M, Ito Y, Yammine S, et al. Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation. Mol Cell Biol (2010) 30(5):1199-216. doi:10.1128/MCB.00827-09
-
(2010)
Mol Cell Biol
, vol.30
, Issue.5
, pp. 1199-216
-
-
Farrar, D.1
Rai, S.2
Chernukhin, I.3
Jagodic, M.4
Ito, Y.5
Yammine, S.6
-
90
-
-
0035863455
-
DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers
-
doi:10.1002/1097-0215(200002)9999:9999<::AID-IJC1040>3.0.CO;2-2
-
Kanai Y, Ushijima S, Kondo Y, Nakanishi Y, Hirohashi S. DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. Int J Cancer (2001) 91(2):205-12. doi:10.1002/1097-0215(200002)9999:9999<::AID-IJC1040>3.0.CO;2-2
-
(2001)
Int J Cancer
, vol.91
, Issue.2
, pp. 205-12
-
-
Kanai, Y.1
Ushijima, S.2
Kondo, Y.3
Nakanishi, Y.4
Hirohashi, S.5
-
91
-
-
61849171655
-
Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity
-
doi:10.1371/journal.pone.0004717
-
Zampieri M, Passananti C, Calabrese R, Perilli M, Corbi N, De Cave F, et al. Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. PLoS One (2009) 4(3):e4717. doi:10.1371/journal.pone.0004717
-
(2009)
PLoS One
, vol.4
, Issue.3
-
-
Zampieri, M.1
Passananti, C.2
Calabrese, R.3
Perilli, M.4
Corbi, N.5
De Cave, F.6
-
92
-
-
84555178345
-
ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites
-
doi:10.1042/BJ20111417
-
Zampieri M, Guastafierro T, Calabrese R, Ciccarone F, Bacalini MG, Reale A, et al. ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites. Biochem J (2012) 441(2):645-52. doi:10.1042/BJ20111417
-
(2012)
Biochem J
, vol.441
, Issue.2
, pp. 645-52
-
-
Zampieri, M.1
Guastafierro, T.2
Calabrese, R.3
Ciccarone, F.4
Bacalini, M.G.5
Reale, A.6
-
93
-
-
27144509196
-
DNA methyltransferase inhibitors and the development of epigenetic cancer therapies
-
doi:10.1093/jnci/dji311
-
Lyko F, Brown R. DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J Natl Cancer Inst (2005) 97(20):1498-506. doi:10.1093/jnci/dji311
-
(2005)
J Natl Cancer Inst
, vol.97
, Issue.20
, pp. 1498-506
-
-
Lyko, F.1
Brown, R.2
-
94
-
-
34249898088
-
SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery
-
doi:10.1038/nsmb1248
-
Gamble MJ, Fisher RP. SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery. Nat Struct Mol Biol (2007) 14(6):548-55. doi:10.1038/nsmb1248
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.6
, pp. 548-55
-
-
Gamble, M.J.1
Fisher, R.P.2
-
95
-
-
78650250161
-
Recruitment timing and dynamics of transcription factors at the Hsp70 loci in living cells
-
doi:10.1016/j.molcel.2010.11.022
-
Zobeck KL, Buckley MS, Zipfel WR, Lis JT. Recruitment timing and dynamics of transcription factors at the Hsp70 loci in living cells. Mol Cell (2010) 40(6):965-75. doi:10.1016/j.molcel.2010.11.022
-
(2010)
Mol Cell
, vol.40
, Issue.6
, pp. 965-75
-
-
Zobeck, K.L.1
Buckley, M.S.2
Zipfel, W.R.3
Lis, J.T.4
-
96
-
-
84868444460
-
The PARP inhibitor PJ34 modifies proliferation, NIS expression and epigenetic marks in thyroid cancer cell lines
-
doi:10.1016/j.mce.2012.08.019
-
Lavarone E, Puppin C, Passon N, Filetti S, Russo D, Damante G. The PARP inhibitor PJ34 modifies proliferation, NIS expression and epigenetic marks in thyroid cancer cell lines. Mol Cell Endocrinol (2013) 365(1):1-10. doi:10.1016/j.mce.2012.08.019
-
(2013)
Mol Cell Endocrinol
, vol.365
, Issue.1
, pp. 1-10
-
-
Lavarone, E.1
Puppin, C.2
Passon, N.3
Filetti, S.4
Russo, D.5
Damante, G.6
-
97
-
-
10944253639
-
Activating the PARP-1 sensor component of the groucho/TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway
-
doi:10.1016/j.cell.2004.11.017
-
Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, et al. Activating the PARP-1 sensor component of the groucho/TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell (2004) 119(6):815-29. doi:10.1016/j.cell.2004.11.017
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 815-29
-
-
Ju, B.G.1
Solum, D.2
Song, E.J.3
Lee, K.J.4
Rose, D.W.5
Glass, C.K.6
-
98
-
-
20144389926
-
PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator
-
doi:10.1016/j.molcel.2005.02.034
-
Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, et al. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol Cell (2005) 18(1):83-96. doi:10.1016/j.molcel.2005.02.034
-
(2005)
Mol Cell
, vol.18
, Issue.1
, pp. 83-96
-
-
Pavri, R.1
Lewis, B.2
Kim, T.K.3
Dilworth, F.J.4
Erdjument-Bromage, H.5
Tempst, P.6
-
99
-
-
0035937826
-
A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression
-
doi:10.1074/jbc.M009897200
-
Nirodi C, NagDas S, Gygi SP, Olson G, Aebersold R, Richmond A. A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression. J Biol Chem (2001) 276(12):9366-74. doi:10.1074/jbc.M009897200
-
(2001)
J Biol Chem
, vol.276
, Issue.12
, pp. 9366-74
-
-
Nirodi, C.1
NagDas, S.2
Gygi, S.P.3
Olson, G.4
Aebersold, R.5
Richmond, A.6
-
100
-
-
0346122893
-
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase
-
doi:10.1038/sj.onc.1206897
-
Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Samara R, Espinoza LA, Hassa PO, et al. PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. Oncogene (2003) 22(52):8460-71. doi:10.1038/sj.onc.1206897
-
(2003)
Oncogene
, vol.22
, Issue.52
, pp. 8460-71
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Luo, R.3
Samara, R.4
Espinoza, L.A.5
Hassa, P.O.6
-
101
-
-
0344258423
-
PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation
-
doi:10.1093/nar/27.3.866
-
Kannan P, Yu Y, Wankhade S, Tainsky MA. PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation. Nucleic Acids Res (1999) 27(3):866-74. doi:10.1093/nar/27.3.866
-
(1999)
Nucleic Acids Res
, vol.27
, Issue.3
, pp. 866-74
-
-
Kannan, P.1
Yu, Y.2
Wankhade, S.3
Tainsky, M.A.4
-
102
-
-
0031012251
-
AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression
-
doi:10.1038/ng0197-78
-
Zeng Y-X, Somasundaram K, El-Deiry WS. AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression. Nat Genet (1997) 15(1):78-82. doi:10.1038/ng0197-78
-
(1997)
Nat Genet
, vol.15
, Issue.1
, pp. 78-82
-
-
Zeng, Y.-X.1
Somasundaram, K.2
El-Deiry, W.S.3
-
103
-
-
78649791361
-
Identification of PARP-1 as one of the transcription factors binding to the repressor element in the promoter region of COX-2
-
doi:10.1016/j.abb.2010.09.016
-
Lin Y, Tang X, Zhu Y, Shu T, Han X. Identification of PARP-1 as one of the transcription factors binding to the repressor element in the promoter region of COX-2. Arch Biochem Biophys (2011) 505(1):123-9. doi:10.1016/j.abb.2010.09.016
-
(2011)
Arch Biochem Biophys
, vol.505
, Issue.1
, pp. 123-9
-
-
Lin, Y.1
Tang, X.2
Zhu, Y.3
Shu, T.4
Han, X.5
-
104
-
-
80054856209
-
RAS oncogenes: weaving a tumorigenic web
-
doi:10.1038/nrc3106
-
Pylayeva-Gupta Y, Grabocka E, Bar-Sagi D. RAS oncogenes: weaving a tumorigenic web. Nat Rev Cancer (2011) 11(11):761-74. doi:10.1038/nrc3106
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.11
, pp. 761-74
-
-
Pylayeva-Gupta, Y.1
Grabocka, E.2
Bar-Sagi, D.3
-
105
-
-
77956944344
-
Influence of sex hormones on cancer progression
-
doi:10.1200/JCO.2009.27.4290
-
Folkerd EJ, Dowsett M. Influence of sex hormones on cancer progression. J Clin Oncol (2010) 28(26):4038-44. doi:10.1200/JCO.2009.27.4290
-
(2010)
J Clin Oncol
, vol.28
, Issue.26
, pp. 4038-44
-
-
Folkerd, E.J.1
Dowsett, M.2
-
106
-
-
84876531873
-
Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor alpha-dependent gene transcription
-
doi:10.1074/jbc.M112.429134
-
Zhang F, Wang Y, Wang L, Luo X, Huang K, Wang C, et al. Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor alpha-dependent gene transcription. J Biol Chem (2013) 288(16):11348-57. doi:10.1074/jbc.M112.429134
-
(2013)
J Biol Chem
, vol.288
, Issue.16
, pp. 11348-57
-
-
Zhang, F.1
Wang, Y.2
Wang, L.3
Luo, X.4
Huang, K.5
Wang, C.6
-
107
-
-
33745255099
-
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription
-
doi:10.1126/science.1127196
-
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, et al. A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science (2006) 312(5781):1798-802. doi:10.1126/science.1127196
-
(2006)
Science
, vol.312
, Issue.5781
, pp. 1798-802
-
-
Ju, B.G.1
Lunyak, V.V.2
Perissi, V.3
Garcia-Bassets, I.4
Rose, D.W.5
Glass, C.K.6
-
108
-
-
84865839222
-
CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
-
doi:10.1101/gad.193193.112
-
Wright RH, Castellano G, Bonet J, Le Dily F, Font-Mateu J, Ballare C, et al. CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. Genes Dev (2012) 26(17):1972-83. doi:10.1101/gad.193193.112
-
(2012)
Genes Dev
, vol.26
, Issue.17
, pp. 1972-83
-
-
Wright, R.H.1
Castellano, G.2
Bonet, J.3
Le Dily, F.4
Font-Mateu, J.5
Ballare, C.6
-
109
-
-
10744232066
-
Poly(ADP-ribose) polymerase-1, a novel partner of progesterone receptors in endometrial cancer and its precursors
-
doi:10.1002/ijc.11731
-
Ghabreau L, Roux JP, Frappart PO, Mathevet P, Patricot LM, Mokni M, et al. Poly(ADP-ribose) polymerase-1, a novel partner of progesterone receptors in endometrial cancer and its precursors. Int J Cancer (2004) 109(3):317-21. doi:10.1002/ijc.11731
-
(2004)
Int J Cancer
, vol.109
, Issue.3
, pp. 317-21
-
-
Ghabreau, L.1
Roux, J.P.2
Frappart, P.O.3
Mathevet, P.4
Patricot, L.M.5
Mokni, M.6
-
110
-
-
84871516837
-
Dual roles of PARP-1 promote cancer growth and progression
-
doi:10.1158/2159-8290.CD-12-0120
-
Schiewer MJ, Goodwin JF, Han S, Brenner JC, Augello MA, Dean JL, et al. Dual roles of PARP-1 promote cancer growth and progression. Cancer Discov (2012) 2(12):1134-49. doi:10.1158/2159-8290.CD-12-0120
-
(2012)
Cancer Discov
, vol.2
, Issue.12
, pp. 1134-49
-
-
Schiewer, M.J.1
Goodwin, J.F.2
Han, S.3
Brenner, J.C.4
Augello, M.A.5
Dean, J.L.6
-
111
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
doi:10.1038/nature06548
-
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature (2008) 451(7182):1111-5. doi:10.1038/nature06548
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-5
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
|