PARP-1 Modulation of mTOR Signaling in Response to a DNA Alkylating Agent

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Éthier, Chantal ^a   Tardif, Maxime ^a   Arul, Laura ^a   Poirier, Guy G ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALKYLATING AGENT; CELL DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; N METHYL N' NITRO N' NITROSGUANINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN KINASE B; PROTEIN S6; REACTIVE OXYGEN METABOLITE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL ENERGY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALKYLATING AGENTS; AMP-ACTIVATED PROTEIN KINASES; AUTOPHAGY; BLOTTING, WESTERN; ENZYME ACTIVATION; HEK293 CELLS; HELA CELLS; HUMANS; METHYLNITRONITROSOGUANIDINE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; NAD; NECROSIS; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

RAPTORES;

EID: 84868118383     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047978     Document Type: Article

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