Targeting the extracellular signal-regulated kinase pathway in cancer therapy

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 12, 2011, Pages 1781-1784

  Kohno, Michiaki ^a   Tanimura, Susumu ^a   Ozaki, Kei Ichi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Anticancer drug; Combination therapy; ERK pathway; MEK inhibitor; Molecular targeted therapy

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; AFATINIB; ANTINEOPLASTIC AGENT; BMS 908662; DABRAFENIB; ERLOTINIB; GDC 0973; GEFITINIB; HISTONE DEACETYLASE INHIBITOR; ICOTINIB; LAPATINIB; MICROTUBULE DESTABILIZING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MSC 1936369; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; NAVELBINE; RDEA 119; RO 4987655; ROMIDEPSIN; SELUMETINIB; SOBLIDOTIN; TRAMETINIB; TRICHOSTATIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VARLITINIB; VEMURAFENIB; VINCRISTINE;

ADVANCED CANCER; APOPTOSIS; ARTICLE; ASTHENIA; CANCER THERAPY; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; DIARRHEA; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG ERUPTION; DRUG POTENTIATION; DRUG SENSITIZATION; DRUG TARGETING; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT NEOPLASTIC DISEASE; NAUSEA AND VOMITING; NONHUMAN; TUMOR CELL; TUMOR XENOGRAFT; UPREGULATION;

EID: 83255162009     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.1781     Document Type: Article

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