ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites

Biochemical Journal

Volumn 441, Issue 2, 2012, Pages 645-652

  Zampieri, Michele ^a,b   Guastafierro, Tiziana ^a,b   Calabrese, Roberta ^a,b   Ciccarone, Fabio ^a,b   Bacalini, Maria G ^a,b   Reale, Anna ^a,b   Perilli, Mariagrazia ^c   Passananti, Claudio ^d   Caiafa, Paola ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Pasteur Institute   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d CNR   (Italy)

Author keywords

CCCTC binding factor (Ctcf); DNA methylation; DNA methyltranferase 1 (Dnmt1); Epigenetics; Poly(ADP ribose) polymerase 1 (Parp1); Poly(ADP ribosyl)ation (PARylation)

Indexed keywords

DNA METHYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); POLY(ADENOSINE DIPHOSPHATE RIBOSE) GLYCOHYDROLASE; POLYMER; TRANSCRIPTION FACTOR CTCF; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS;

CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; MULTIPROTEIN COMPLEXES; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; REPRESSOR PROTEINS;

EID: 84555178345     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111417     Document Type: Article

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