-
1
-
-
44949151607
-
Viral control of mitochondrial apoptosis
-
Galluzzi, L.; Brenner, C.; Morselli, E.; Touat, Z.; Kroemer, G. Viral control of mitochondrial apoptosis. PLoS Pathog. 2008, 4, e1000018.
-
(2008)
PLoS Pathog
, vol.4
-
-
Galluzzi, L.1
Brenner, C.2
Morselli, E.3
Touat, Z.4
Kroemer, G.5
-
2
-
-
47749140740
-
Akt and mRNA translation by interferons
-
Kaur, S.; Katsoulidis, E.; Platanias, L.C. Akt and mRNA translation by interferons. Cell Cycle 2008, 7, 2112-2116.
-
(2008)
Cell Cycle
, vol.7
, pp. 2112-2116
-
-
Kaur, S.1
Katsoulidis, E.2
Platanias, L.C.3
-
3
-
-
42449150892
-
Role of the Akt pathway in mRNA translation of interferon-stimulated genes
-
Kaur, S.; Sassano, A.; Dolniak, B.; Joshi, S.; Majchrzak-Kita, B.; Baker, D.P.; Hay, N.; Fish, E.N.; Platanias, L.C. Role of the Akt pathway in mRNA translation of interferon-stimulated genes. Proc. Natl. Acad. Sci. USA 2008, 105, 4808-4813.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4808-4813
-
-
Kaur, S.1
Sassano, A.2
Dolniak, B.3
Joshi, S.4
Majchrzak-Kita, B.5
Baker, D.P.6
Hay, N.7
Fish, E.N.8
Platanias, L.C.9
-
4
-
-
58149179174
-
Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling
-
Kaur, S.; Sassano, A.; Joseph, A.M.; Majchrzak-Kita, B.; Eklund, E.A.; Verma, A.; Brachmann, S.M.; Fish, E.N.; Platanias, L.C. Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling. J. Immunol. 2008, 181, 7316-7323.
-
(2008)
J. Immunol
, vol.181
, pp. 7316-7323
-
-
Kaur, S.1
Sassano, A.2
Joseph, A.M.3
Majchrzak-Kita, B.4
Eklund, E.A.5
Verma, A.6
Brachmann, S.M.7
Fish, E.N.8
Platanias, L.C.9
-
5
-
-
77953430564
-
Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus
-
Freudenburg, W.; Moran, J.M.; Lents, N.H.; Baldassare, J.J.; Buller, R.M.; Corbett, J.A. Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus. J. Innate Immun. 2010, 2, 77-86.
-
(2010)
J. Innate Immun
, vol.2
, pp. 77-86
-
-
Freudenburg, W.1
Moran, J.M.2
Lents, N.H.3
Baldassare, J.J.4
Buller, R.M.5
Corbett, J.A.6
-
6
-
-
31344477977
-
Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kappaB activation
-
Chang, T.H.; Liao, C.L.; Lin, Y.L. Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kappaB activation. Microbes Infect. 2006, 8, 157-171.
-
(2006)
Microbes Infect
, vol.8
, pp. 157-171
-
-
Chang, T.H.1
Liao, C.L.2
Lin, Y.L.3
-
7
-
-
77951621262
-
The emerging mechanisms of isoform-specific PI3K signalling
-
Vanhaesebroeck, B.; Guillermet-Guibert, J.; Graupera, M.; Bilanges, B. The emerging mechanisms of isoform-specific PI3K signalling. Nat. Rev. Mol. Cell Biol. 2010, 11, 329-341.
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 329-341
-
-
Vanhaesebroeck, B.1
Guillermet-Guibert, J.2
Graupera, M.3
Bilanges, B.4
-
8
-
-
0035020950
-
Phosphoinositide 3-kinase signalling pathways
-
Cantrell, D.A. Phosphoinositide 3-kinase signalling pathways. J. Cell Sci. 2001, 114, 1439-1445.
-
(2001)
J. Cell Sci
, vol.114
, pp. 1439-1445
-
-
Cantrell, D.A.1
-
9
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning, B.D.; Cantley, L.C. AKT/PKB signaling: Navigating downstream. Cell 2007, 129, 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
10
-
-
57649219414
-
In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis
-
Surucu, B.; Bozulic, L.; Hynx, D.; Parcellier, A.; Hemmings, B.A. In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis. J. Biol. Chem. 2008, 283, 30025-30033.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 30025-30033
-
-
Surucu, B.1
Bozulic, L.2
Hynx, D.3
Parcellier, A.4
Hemmings, B.A.5
-
11
-
-
42949165854
-
PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival
-
Bozulic, L.; Surucu, B.; Hynx, D.; Hemmings, B.A. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol. Cell 2008, 30, 203-213.
-
(2008)
Mol. Cell
, vol.30
, pp. 203-213
-
-
Bozulic, L.1
Surucu, B.2
Hynx, D.3
Hemmings, B.A.4
-
12
-
-
0000714961
-
Regulation of protein kinase cascades by protein phosphatase 2A
-
Millward, T.A.; Zolnierowicz, S.; Hemmings, B.A. Regulation of protein kinase cascades by protein phosphatase 2A. Trends Biochem. Sci. 1999, 24, 186-191.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 186-191
-
-
Millward, T.A.1
Zolnierowicz, S.2
Hemmings, B.A.3
-
13
-
-
15944406764
-
PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
-
Gao, T.; Furnari, F.; Newton, A.C. PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol. Cell 2005, 18, 13-24.
-
(2005)
Mol. Cell
, vol.18
, pp. 13-24
-
-
Gao, T.1
Furnari, F.2
Newton, A.C.3
-
14
-
-
84877851454
-
Quantitative phosphoproteomics reveals extensive cellular reprogramming during HIV-1 entry
-
Wojcechowskyj, J.A.; Didigu, C.A.; Lee, J.Y.; Parrish, N.F.; Sinha, R.; Hahn, B.H.; Bushman, F.D.; Jensen, S.T.; Seeholzer, S.H.; Doms, R.W. Quantitative phosphoproteomics reveals extensive cellular reprogramming during HIV-1 entry. Cell Host Microbe 2013, 13, 613-623.
-
(2013)
Cell Host Microbe
, vol.13
, pp. 613-623
-
-
Wojcechowskyj, J.A.1
Didigu, C.A.2
Lee, J.Y.3
Parrish, N.F.4
Sinha, R.5
Hahn, B.H.6
Bushman, F.D.7
Jensen, S.T.8
Seeholzer, S.H.9
Doms, R.W.10
-
15
-
-
77955770216
-
Mechanisms of viral entry: Sneaking in the front door
-
Thorley, J.A.; McKeating, J.A.; Rappoport, J.Z. Mechanisms of viral entry: Sneaking in the front door. Protoplasma 2010, 244, 15-24.
-
(2010)
Protoplasma
, vol.244
, pp. 15-24
-
-
Thorley, J.A.1
McKeating, J.A.2
Rappoport, J.Z.3
-
16
-
-
77952692673
-
Virus entry by endocytosis
-
Mercer, J.; Schelhaas, M.; Helenius, A. Virus entry by endocytosis. Annu. Rev. Biochem. 2010, 79, 803-833.
-
(2010)
Annu. Rev. Biochem
, vol.79
, pp. 803-833
-
-
Mercer, J.1
Schelhaas, M.2
Helenius, A.3
-
17
-
-
4043071312
-
Endocytosis of influenza viruses
-
Lakadamyali, M.; Rust, M.J.; Zhuang, X. Endocytosis of influenza viruses. Microbes Infect. 2004, 6, 929-936.
-
(2004)
Microbes Infect
, vol.6
, pp. 929-936
-
-
Lakadamyali, M.1
Rust, M.J.2
Zhuang, X.3
-
18
-
-
79952088584
-
The role of lipids in retrovirus replication
-
Waheed, A.A.; Freed, E.O. The role of lipids in retrovirus replication. Viruses 2010, 2, 1146-1180.
-
(2010)
Viruses
, vol.2
, pp. 1146-1180
-
-
Waheed, A.A.1
Freed, E.O.2
-
19
-
-
0041494100
-
Lipid rafts: Bringing order to chaos
-
Pike, L.J. Lipid rafts: Bringing order to chaos. J. Lipid Res. 2003, 44, 655-667.
-
(2003)
J. Lipid Res
, vol.44
, pp. 655-667
-
-
Pike, L.J.1
-
20
-
-
78149333191
-
The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells
-
Eierhoff, T.; Hrincius, E.R.; Rescher, U.; Ludwig, S.; Ehrhardt, C. The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells. PLoS Pathog. 2010, 6, e1001099.
-
(2010)
PLoS Pathog
, vol.6
-
-
Eierhoff, T.1
Hrincius, E.R.2
Rescher, U.3
Ludwig, S.4
Ehrhardt, C.5
-
21
-
-
79251616335
-
The Ras-PI3K signaling pathway is involved in clathrin-independent endocytosis and the internalization of influenza viruses
-
Fujioka, Y.; Tsuda, M.; Hattori, T.; Sasaki, J.; Sasaki, T.; Miyazaki, T.; Ohba, Y. The Ras-PI3K signaling pathway is involved in clathrin-independent endocytosis and the internalization of influenza viruses. PLoS One 2011, 6, e16324.
-
(2011)
PLoS One
, vol.6
-
-
Fujioka, Y.1
Tsuda, M.2
Hattori, T.3
Sasaki, J.4
Sasaki, T.5
Miyazaki, T.6
Ohba, Y.7
-
22
-
-
79952664121
-
Influenza A virus-induced early activation of ERK and PI3K mediates V-ATPase-dependent intracellular pH change required for fusion
-
Marjuki, H.; Gornitzky, A.; Marathe, B.M.; Ilyushina, N.A.; Aldridge, J.R.; Desai, G.; Webby, R.J.; Webster, R.G. Influenza A virus-induced early activation of ERK and PI3K mediates V-ATPase-dependent intracellular pH change required for fusion. Cell. Microbiol. 2011, 13, 587-601.
-
(2011)
Cell. Microbiol
, vol.13
, pp. 587-601
-
-
Marjuki, H.1
Gornitzky, A.2
Marathe, B.M.3
Ilyushina, N.A.4
Aldridge, J.R.5
Desai, G.6
Webby, R.J.7
Webster, R.G.8
-
23
-
-
84864013018
-
Integrin beta1 mediates vaccinia virus entry through activation of PI3K/Akt signaling
-
Izmailyan, R.; Hsao, J.C.; Chung, C.S.; Chen, C.H.; Hsu, P.W.; Liao, C.L.; Chang, W. Integrin beta1 mediates vaccinia virus entry through activation of PI3K/Akt signaling. J. Virol.2012, 86, 6677-6687.
-
(2012)
J. Virol
, vol.86
, pp. 6677-6687
-
-
Izmailyan, R.1
Hsao, J.C.2
Chung, C.S.3
Chen, C.H.4
Hsu, P.W.5
Liao, C.L.6
Chang, W.7
-
24
-
-
0037025313
-
Beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway
-
Tian, B.; Lessan, K.; Kahm, J.; Kleidon, J.; Henke, C. Beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway. J. Biol. Chem. 2002, 277, 24667-24675.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 24667-24675
-
-
Tian, B.1
Lessan, K.2
Kahm, J.3
Kleidon, J.4
Henke, C.5
-
25
-
-
50849144350
-
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus
-
Saeed, M.F.; Kolokoltsov, A.A.; Freiberg, A.N.; Holbrook, M.R.; Davey, R.A. Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus. PLoS Pathog. 2008, 4, e1000141.
-
(2008)
PLoS Pathog
, vol.4
-
-
Saeed, M.F.1
Kolokoltsov, A.A.2
Freiberg, A.N.3
Holbrook, M.R.4
Davey, R.A.5
-
26
-
-
84871280686
-
Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry
-
Liu, Z.; Tian, Y.; Machida, K.; Lai, M.M.; Luo, G.; Foung, S.K.; Ou, J.H. Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry. J. Biol. Chem. 2012, 287, 41922-41930.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 41922-41930
-
-
Liu, Z.1
Tian, Y.2
Machida, K.3
Lai, M.M.4
Luo, G.5
Foung, S.K.6
Ou, J.H.7
-
27
-
-
79959302808
-
The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses
-
Feng, S.Z.; Cao, W.S.; Liao, M. The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses. J. Gen. Virol. 2011, 92, 1688-1697.
-
(2011)
J. Gen. Virol
, vol.92
, pp. 1688-1697
-
-
Feng, S.Z.1
Cao, W.S.2
Liao, M.3
-
28
-
-
72949083492
-
A role for heparan sulfate in viral surfing
-
Oh, M.J.; Akhtar, J.; Desai, P.; Shukla, D. A role for heparan sulfate in viral surfing. Biochem. Biophys. Res. Commun. 2010, 391, 176-181.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.391
, pp. 176-181
-
-
Oh, M.J.1
Akhtar, J.2
Desai, P.3
Shukla, D.4
-
29
-
-
78650070161
-
Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry
-
Tiwari, V.; Shukla, D. Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry. J. Gen. Virol. 2010, 91, 3002-3009.
-
(2010)
J. Gen. Virol
, vol.91
, pp. 3002-3009
-
-
Tiwari, V.1
Shukla, D.2
-
30
-
-
84875079560
-
African swine fever virus uses macropinocytosis to enter host cells
-
Sanchez, E.G.; Quintas, A.; Perez-Nunez, D.; Nogal, M.; Barroso, S.; Carrascosa, A.L.; Revilla, Y. African swine fever virus uses macropinocytosis to enter host cells. PLoS Pathog. 2012, 8, e1002754.
-
(2012)
PLoS Pathog
, vol.8
-
-
Sanchez, E.G.1
Quintas, A.2
Perez-Nunez, D.3
Nogal, M.4
Barroso, S.5
Carrascosa, A.L.6
Revilla, Y.7
-
31
-
-
84873022115
-
Pick one, but be quick: 5' splice sites and the problems of too many choices
-
Roca, X.; Krainer, A.R.; Eperon, I.C. Pick one, but be quick: 5' splice sites and the problems of too many choices. Genes Dev. 2013, 27, 129-144.
-
(2013)
Genes Dev
, vol.27
, pp. 129-144
-
-
Roca, X.1
Krainer, A.R.2
Eperon, I.C.3
-
32
-
-
38349127601
-
Combinatorial control of exon recognition
-
Hertel, K.J. Combinatorial control of exon recognition. J. Biol. Chem. 2008, 283, 1211-1215.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1211-1215
-
-
Hertel, K.J.1
-
33
-
-
84871401549
-
Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms
-
Erkelenz, S.; Mueller, W.F.; Evans, M.S.; Busch, A.; Schoneweis, K.; Hertel, K.J.; Schaal, H. Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms. RNA 2013, 19, 96-102.
-
(2013)
RNA
, vol.19
, pp. 96-102
-
-
Erkelenz, S.1
Mueller, W.F.2
Evans, M.S.3
Busch, A.4
Schoneweis, K.5
Hertel, K.J.6
Schaal, H.7
-
34
-
-
69949167523
-
Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons
-
Jang, S.W.; Liu, X.; Fu, H.; Rees, H.; Yepes, M.; Levey, A.; Ye, K. Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons. J. Biol. Chem. 2009, 284, 24512-24525.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 24512-24525
-
-
Jang, S.W.1
Liu, X.2
Fu, H.3
Rees, H.4
Yepes, M.5
Levey, A.6
Ye, K.7
-
35
-
-
84864910082
-
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
-
Zhou, Z.; Qiu, J.; Liu, W.; Zhou, Y.; Plocinik, R.M.; Li, H.; Hu, Q.; Ghosh, G.; Adams, J.A.; Rosenfeld, M.G., et al. The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol. Cell 2012, 47, 422-433.
-
(2012)
Mol. Cell
, vol.47
, pp. 422-433
-
-
Zhou, Z.1
Qiu, J.2
Liu, W.3
Zhou, Y.4
Plocinik, R.M.5
Li, H.6
Hu, Q.7
Ghosh, G.8
Adams, J.A.9
Rosenfeld, M.G.10
-
36
-
-
28544450763
-
Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT
-
Blaustein, M.; Pelisch, F.; Tanos, T.; Munoz, M.J.; Wengier, D.; Quadrana, L.; Sanford, J.R.; Muschietti, J.P.; Kornblihtt, A.R.; Caceres, J.F., et al. Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT. Nat. Struct. Mol. Biol. 2005, 12, 1037-1044.
-
(2005)
Nat. Struct. Mol. Biol
, vol.12
, pp. 1037-1044
-
-
Blaustein, M.1
Pelisch, F.2
Tanos, T.3
Munoz, M.J.4
Wengier, D.5
Quadrana, L.6
Sanford, J.R.7
Muschietti, J.P.8
Kornblihtt, A.R.9
Caceres, J.F.10
-
37
-
-
66449111724
-
Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid
-
Jiang, K.; Patel, N.A.; Watson, J.E.; Apostolatos, H.; Kleiman, E.; Hanson, O.; Hagiwara, M.; Cooper, D.R. Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid. Endocrinology 2009, 150, 2087-2097.
-
(2009)
Endocrinology
, vol.150
, pp. 2087-2097
-
-
Jiang, K.1
Patel, N.A.2
Watson, J.E.3
Apostolatos, H.4
Kleiman, E.5
Hanson, O.6
Hagiwara, M.7
Cooper, D.R.8
-
38
-
-
78549234102
-
Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a
-
Shultz, J.C.; Goehe, R.W.; Wijesinghe, D.S.; Murudkar, C.; Hawkins, A.J.; Shay, J.W.; Minna, J.D.; Chalfant, C.E. Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a. Cancer Res. 2010, 70, 9185-9196.
-
(2010)
Cancer Res
, vol.70
, pp. 9185-9196
-
-
Shultz, J.C.1
Goehe, R.W.2
Wijesinghe, D.S.3
Murudkar, C.4
Hawkins, A.J.5
Shay, J.W.6
Minna, J.D.7
Chalfant, C.E.8
-
39
-
-
84875428613
-
Hnrnp U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L
-
Vu, N.T.; Park, M.A.; Shultz, J.C.; Goehe, R.W.; Hoeferlin, L.A.; Shultz, M.D.; Smith, S.A.; Lynch, K.W.; Chalfant, C.E. Hnrnp U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L. J. Biol. Chem. 2013, 288, 8575-8584.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 8575-8584
-
-
Vu, N.T.1
Park, M.A.2
Shultz, J.C.3
Goehe, R.W.4
Hoeferlin, L.A.5
Shultz, M.D.6
Smith, S.A.7
Lynch, K.W.8
Chalfant, C.E.9
-
40
-
-
0033104331
-
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis
-
Srinivasula, S.M.; Ahmad, M.; Guo, Y.; Zhan, Y.; Lazebnik, Y.; Fernandes-Alnemri, T.; Alnemri, E.S. Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Res. 1999, 59, 999-1002.
-
(1999)
Cancer Res
, vol.59
, pp. 999-1002
-
-
Srinivasula, S.M.1
Ahmad, M.2
Guo, Y.3
Zhan, Y.4
Lazebnik, Y.5
Fernandes-Alnemri, T.6
Alnemri, E.S.7
-
41
-
-
0344406975
-
ASAP, a novel protein complex involved in NA processing and apoptosis
-
Schwerk, C.; Prasad, J.; Degenhardt, K.; Erdjument-Bromage, H.; White, E.; Tempst, P.; Kidd, V.J.; Manley, J.L.; Lahti, J.M.; Reinberg, D. ASAP, a novel protein complex involved in NA processing and apoptosis. Mol. Cell. Biol. 2003, 23, 2981-2990.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 2981-2990
-
-
Schwerk, C.1
Prasad, J.2
Degenhardt, K.3
Erdjument-Bromage, H.4
White, E.5
Tempst, P.6
Kidd, V.J.7
Manley, J.L.8
Lahti, J.M.9
Reinberg, D.10
-
42
-
-
78649639485
-
Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold
-
Singh, K.K.; Erkelenz, S.; Rattay, S.; Dehof, A.K.; Hildebrandt, A.; Schulze-Osthoff, K.; Schaal, H.; Schwerk, C. Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold. RNA 2010, 16, 2442-2454.
-
(2010)
RNA
, vol.16
, pp. 2442-2454
-
-
Singh, K.K.1
Erkelenz, S.2
Rattay, S.3
Dehof, A.K.4
Hildebrandt, A.5
Schulze-Osthoff, K.6
Schaal, H.7
Schwerk, C.8
-
43
-
-
27144446343
-
Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation
-
Hu, Y.; Yao, J.; Liu, Z.; Liu, X.; Fu, H.; Ye, K. Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation. EMBO J. 2005, 24, 3543-3554.
-
(2005)
EMBO J
, vol.24
, pp. 3543-3554
-
-
Hu, Y.1
Yao, J.2
Liu, Z.3
Liu, X.4
Fu, H.5
Ye, K.6
-
44
-
-
33749552159
-
Measles virus induces expression of SIP110, a constitutively membrane clustered lipid phosphatase, which inhibits T cell proliferation
-
Avota, E.; Harms, H.; Schneider-Schaulies, S. Measles virus induces expression of SIP110, a constitutively membrane clustered lipid phosphatase, which inhibits T cell proliferation. ell. Microbiol. 2006, 8, 1826-1839.
-
(2006)
Ell. Microbiol
, vol.8
, pp. 1826-1839
-
-
Avota, E.1
Harms, H.2
Schneider-Schaulies, S.3
-
45
-
-
84873267548
-
Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells
-
Riedel, A.; Mofolo, B.; Avota, E.; Schneider-Schaulies, S.; Meintjes, A.; Mulder, N.; Kneitz, S. Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells. LoS One 2013, 8, e50695.
-
(2013)
LoS One
, vol.8
-
-
Riedel, A.1
Mofolo, B.2
Avota, E.3
Schneider-Schaulies, S.4
Meintjes, A.5
Mulder, N.6
Kneitz, S.7
-
46
-
-
0035865268
-
The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins
-
Estmer Nilsson, C.; Petersen-Mahrt, S.; Durot, C.; Shtrichman, R.; Krainer, A.R.; Kleinberger, T.; Akusjarvi, G. The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins. EMBO J. 2001, 20, 864-871.
-
(2001)
EMBO J
, vol.20
, pp. 864-871
-
-
Nilsson, E.C.1
Petersen-Mahrt, S.2
Durot, C.3
Shtrichman, R.4
Krainer, A.R.5
Kleinberger, T.6
Akusjarvi, G.7
-
47
-
-
0037387122
-
ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation
-
Sciabica, K.S.; Dai, Q.J.; Sandri-Goldin, R.M. ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation. EMBO J. 2003, 22, 1608-1619.
-
(2003)
EMBO J
, vol.22
, pp. 1608-1619
-
-
Sciabica, K.S.1
Dai, Q.J.2
Sandri-Goldin, R.M.3
-
48
-
-
41049087051
-
HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages
-
doi:10.1186/1742-4690-5-18
-
Dowling, D.; Nasr-Esfahani, S.; Tan, C.H.; O'Brien, K.; Howard, J.L.; Jans, D.A.; Purcell, D.F.; Stoltzfus, C.M.; Sonza, S. HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages. Retrovirology 2008, 5, doi:10.1186/1742-4690-5-18.
-
(2008)
Retrovirology
, pp. 5
-
-
Dowling, D.1
Nasr-Esfahani, S.2
Tan, C.H.3
O'Brien, K.4
Howard, J.L.5
Jans, D.A.6
Purcell, D.F.7
Stoltzfus, C.M.8
Sonza, S.9
-
50
-
-
58149175555
-
The life of a cell: Apoptosis regulation by the PI3K/PKB pathway
-
Duronio, V. The life of a cell: Apoptosis regulation by the PI3K/PKB pathway. Biochem. J. 2008, 415, 333-344.
-
(2008)
Biochem. J
, vol.415
, pp. 333-344
-
-
Duronio, V.1
-
51
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S.R.; Brunet, A.; Greenberg, M.E. Cellular survival: A play in three Akts. Genes Dev. 1999, 13, 2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
52
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta, S.R.; Dudek, H.; Tao, X.; Masters, S.; Fu, H.; Gotoh, Y.; Greenberg, M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997, 91, 231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
53
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs, W.H., 3rd; Meisenhelder, J.; Hunter, T.; Cavenee, W.K.; Arden, K.C. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. USA 1999, 96, 7421-7426.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7421-7426
-
-
Biggs III, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
54
-
-
0029924156
-
The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1
-
Graziani, A.; Galimi, F.; Medico, E.; Cottone, E.; Gramaglia, D.; Boccaccio, C.; Comoglio, P.M. The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1. J. Biol. Chem. 1996, 271, 6590-6593.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 6590-6593
-
-
Graziani, A.1
Galimi, F.2
Medico, E.3
Cottone, E.4
Gramaglia, D.5
Boccaccio, C.6
Comoglio, P.M.7
-
55
-
-
0035173735
-
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
-
Wolf, D.; Witte, V.; Laffert, B.; Blume, K.; Stromer, E.; Trapp, S.; d'Aloja, P.; Schurmann, A.; Baur, A.S. HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Nat. Med. 2001, 7, 1217-1224.
-
(2001)
Nat. Med
, vol.7
, pp. 1217-1224
-
-
Wolf, D.1
Witte, V.2
Laffert, B.3
Blume, K.4
Stromer, E.5
Trapp, S.6
D'Aloja, P.7
Schurmann, A.8
Baur, A.S.9
-
56
-
-
54449099369
-
The multifunctional NS1 protein of influenza A viruses
-
Hale, B.G.; Randall, R.E.; Ortin, J.; Jackson, D. The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 2008, 89, 2359-2376.
-
(2008)
J. Gen. Virol
, vol.89
, pp. 2359-2376
-
-
Hale, B.G.1
Randall, R.E.2
Ortin, J.3
Jackson, D.4
-
57
-
-
33947381763
-
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses
-
Ehrhardt, C.; Wolff, T.; Pleschka, S.; Planz, O.; Beermann, W.; Bode, J.G.; Schmolke, M.; Ludwig, S. Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses. J. Virol. 2007, 81, 3058-3067.
-
(2007)
J. Virol
, vol.81
, pp. 3058-3067
-
-
Ehrhardt, C.1
Wolff, T.2
Pleschka, S.3
Planz, O.4
Beermann, W.5
Bode, J.G.6
Schmolke, M.7
Ludwig, S.8
-
58
-
-
33749004778
-
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling
-
Hale, B.G.; Jackson, D.; Chen, Y.H.; Lamb, R.A.; Randall, R.E. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proc. Natl. Acad. Sci. USA 2006, 103, 14194-14199.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14194-14199
-
-
Hale, B.G.1
Jackson, D.2
Chen, Y.H.3
Lamb, R.A.4
Randall, R.E.5
-
59
-
-
33846160497
-
Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K
-
Shin, Y.K.; Liu, Q.; Tikoo, S.K.; Babiuk, L.A.; Zhou, Y. Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K. J. Gen. Virol. 2007, 88, 13-18.
-
(2007)
J. Gen. Virol
, vol.88
, pp. 13-18
-
-
Shin, Y.K.1
Liu, Q.2
Tikoo, S.K.3
Babiuk, L.A.4
Zhou, Y.5
-
60
-
-
34250828457
-
Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling
-
Zhirnov, O.P.; Klenk, H.D. Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling. Apoptosis 2007, 12, 1419-1432.
-
(2007)
Apoptosis
, vol.12
, pp. 1419-1432
-
-
Zhirnov, O.P.1
Klenk, H.D.2
-
61
-
-
70649096928
-
Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K)
-
Jackson, D.; Killip, M.J.; Galloway, C.S.; Russell, R.J.; Randall, R.E. Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K). Virology 2010, 396, 94-105.
-
(2010)
Virology
, vol.396
, pp. 94-105
-
-
Jackson, D.1
Killip, M.J.2
Galloway, C.S.3
Russell, R.J.4
Randall, R.E.5
-
62
-
-
84872865078
-
Influenza A viruses and PI3K: Are there time, place and manner restrictions?
-
Ayllon, J.; Garcia-Sastre, A.; Hale, B.G. Influenza A viruses and PI3K: Are there time, place and manner restrictions? Virulence 2012, 3, 411-414.
-
(2012)
Virulence
, vol.3
, pp. 411-414
-
-
Ayllon, J.1
Garcia-Sastre, A.2
Hale, B.G.3
-
63
-
-
84861312430
-
Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence
-
Ayllon, J.; Hale, B.G.; Garcia-Sastre, A. Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence. J. Virol. 2012, 86, 5366-5370.
-
(2012)
J. Virol
, vol.86
, pp. 5366-5370
-
-
Ayllon, J.1
Hale, B.G.2
Garcia-Sastre, A.3
-
64
-
-
33645240426
-
Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1
-
Benetti, L.; Roizman, B. Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1. J. Virol. 2006, 80, 3341-3348.
-
(2006)
J. Virol
, vol.80
, pp. 3341-3348
-
-
Benetti, L.1
Roizman, B.2
-
65
-
-
0036200413
-
Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt
-
Yu, Y.; Alwine, J.C. Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt. J. Virol. 2002, 76, 3731-3738.
-
(2002)
J. Virol
, vol.76
, pp. 3731-3738
-
-
Yu, Y.1
Alwine, J.C.2
-
66
-
-
0037423201
-
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling
-
Dawson, C.W.; Tramountanis, G.; Eliopoulos, A.G.; Young, L.S. Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling. J. Biol. Chem. 2003, 278, 3694-3704.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 3694-3704
-
-
Dawson, C.W.1
Tramountanis, G.2
Eliopoulos, A.G.3
Young, L.S.4
-
67
-
-
0034974152
-
Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation
-
Darr, C.D.; Mauser, A.; Kenney, S. Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J. Virol. 2001, 75, 6135-6142.
-
(2001)
J. Virol
, vol.75
, pp. 6135-6142
-
-
Darr, C.D.1
Mauser, A.2
Kenney, S.3
-
68
-
-
76249099841
-
Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency
-
Peng, L.; Wu, T.T.; Tchieu, J.H.; Feng, J.; Brown, H.J.; Feng, J.; Li, X.; Qi, J.; Deng, H.; Vivanco, I., et al. Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency. J. Gen. Virol. 2010, 91, 463-469.
-
(2010)
J. Gen. Virol
, vol.91
, pp. 463-469
-
-
Peng, L.1
Wu, T.T.2
Tchieu, J.H.3
Feng, J.4
Brown, H.J.5
Feng, J.6
Li, X.7
Qi, J.8
Deng, H.9
Vivanco, I.10
-
69
-
-
2442686585
-
The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival
-
Cooray, S. The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival. J. Gen. Virol. 2004, 85, 1065-1076.
-
(2004)
J. Gen. Virol
, vol.85
, pp. 1065-1076
-
-
Cooray, S.1
-
70
-
-
67449090724
-
Activation of the PI3K/Akt pathway early during vaccinia and cowpox virus infections is required for both host survival andviral replication
-
Soares, J.A.; Leite, F.G.; Andrade, L.G.; Torres, A.A.; de Sousa, L.P.; Barcelos, L.S.; Teixeira, M.M.; Ferreira, P.C.; Kroon, E.G.; Souto-Padron, T., et al. Activation of the PI3K/Akt pathway early during vaccinia and cowpox virus infections is required for both host survival andviral replication. J. Virol. 2009, 83, 6883-6899.
-
(2009)
J. Virol
, vol.83
, pp. 6883-6899
-
-
Soares, J.A.1
Leite, F.G.2
Andrade, L.G.3
Torres, A.A.4
de Sousa, L.P.5
Barcelos, L.S.6
Teixeira, M.M.7
Ferreira, P.C.8
Kroon, E.G.9
Souto-Padron, T.10
-
71
-
-
77953306075
-
Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection
-
Bagchi, P.; Dutta, D.; Chattopadhyay, S.; Mukherjee, A.; Halder, U.C.; Sarkar, S.; Kobayashi, N.; Komoto, S.; Taniguchi, K.; Chawla-Sarkar, M. Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection. J. Virol. 2010, 84, 6834-6845.
-
(2010)
J. Virol
, vol.84
, pp. 6834-6845
-
-
Bagchi, P.1
Dutta, D.2
Chattopadhyay, S.3
Mukherjee, A.4
Halder, U.C.5
Sarkar, S.6
Kobayashi, N.7
Komoto, S.8
Taniguchi, K.9
Chawla-Sarkar, M.10
-
72
-
-
37349043240
-
Rotavirus replication in intestinal cells differentially regulates integrin expression by a phosphatidylinositol 3-kinase-dependent pathway, resulting in increased cell adhesion and virus yield
-
Halasz, P.; Holloway, G.; Turner, S.J.; Coulson, B.S. Rotavirus replication in intestinal cells differentially regulates integrin expression by a phosphatidylinositol 3-kinase-dependent pathway, resulting in increased cell adhesion and virus yield. J. Virol. 2008, 82, 148-160.
-
(2008)
J. Virol
, vol.82
, pp. 148-160
-
-
Halasz, P.1
Holloway, G.2
Turner, S.J.3
Coulson, B.S.4
-
73
-
-
0033517189
-
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes, O.N.; Mayo, L.D.; Gustin, J.A.; Pfeffer, S.R.; Pfeffer, L.M.; Donner, D.B. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999, 401, 82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
74
-
-
20744441155
-
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection
-
Lee, C.J.; Liao, C.L.; Lin, Y.L. Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J. Virol. 2005, 79, 8388-8399.
-
(2005)
J. Virol
, vol.79
, pp. 8388-8399
-
-
Lee, C.J.1
Liao, C.L.2
Lin, Y.L.3
-
75
-
-
1842478144
-
The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade
-
Street, A.; Macdonald, A.; Crowder, K.; Harris, M. The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade. J. Biol. Chem. 2004, 279, 12232-12241.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 12232-12241
-
-
Street, A.1
Macdonald, A.2
Crowder, K.3
Harris, M.4
-
76
-
-
21644460984
-
Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: Control of cell survival and viral replication
-
Mannova, P.; Beretta, L. Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: Control of cell survival and viral replication. J. Virol. 2005, 79, 8742-8749.
-
(2005)
J. Virol
, vol.79
, pp. 8742-8749
-
-
Mannova, P.1
Beretta, L.2
-
77
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P.; Warne, P.H.; Dhand, R.; Vanhaesebroeck, B.; Gout, I.; Fry, M.J.; Waterfield, M.D.; Downward, J. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 1994, 370, 527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
78
-
-
0037016747
-
Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway
-
Thomas, K.W.; Monick, M.M.; Staber, J.M.; Yarovinsky, T.; Carter, A.B.; Hunninghake, G.W. Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 2002, 277, 492-501.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 492-501
-
-
Thomas, K.W.1
Monick, M.M.2
Staber, J.M.3
Yarovinsky, T.4
Carter, A.B.5
Hunninghake, G.W.6
-
79
-
-
34548442100
-
Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability
-
Esfandiarei, M.; Boroomand, S.; Suarez, A.; Si, X.; Rahmani, M.; McManus, B. Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability. Cell Microbiol. 2007, 9, 2358-2371.
-
(2007)
Cell Microbiol
, vol.9
, pp. 2358-2371
-
-
Esfandiarei, M.1
Boroomand, S.2
Suarez, A.3
Si, X.4
Rahmani, M.5
McManus, B.6
-
80
-
-
77649188309
-
Activation of PI 3-kinase/Akt/NF-kappaB and Stat3 signaling by avian reovirus S1133 in the early stages of infection results in an inflammatory response and delayed apoptosis
-
Lin, P.Y.; Liu, H.J.; Liao, M.H.; Chang, C.D.; Chang, C.I.; Cheng, H.L.; Lee, J.W.; Shih, W.L. Activation of PI 3-kinase/Akt/NF-kappaB and Stat3 signaling by avian reovirus S1133 in the early stages of infection results in an inflammatory response and delayed apoptosis. Virology 2010, 400, 104-114.
-
(2010)
Virology
, vol.400
, pp. 104-114
-
-
Lin, P.Y.1
Liu, H.J.2
Liao, M.H.3
Chang, C.D.4
Chang, C.I.5
Cheng, H.L.6
Lee, J.W.7
Shih, W.L.8
-
81
-
-
15744404027
-
The involvement of survival signaling pathways in rubella-virus induced apoptosis
-
doi:10.1186/1743-422X-2-1
-
Cooray, S.; Jin, L.; Best, J.M. The involvement of survival signaling pathways in rubella-virus induced apoptosis. Virol. J. 2005, 2, doi:10.1186/1743-422X-2-1.
-
(2005)
Virol. J
, pp. 2
-
-
Cooray, S.1
Jin, L.2
Best, J.M.3
-
82
-
-
4444367035
-
Importance of Akt signaling pathway for apoptosis in SARS-CoV-infected Vero E6 cells
-
Mizutani, T.; Fukushi, S.; Saijo, M.; Kurane, I.; Morikawa, S. Importance of Akt signaling pathway for apoptosis in SARS-CoV-infected Vero E6 cells. Virology 2004, 327, 169-174.
-
(2004)
Virology
, vol.327
, pp. 169-174
-
-
Mizutani, T.1
Fukushi, S.2
Saijo, M.3
Kurane, I.4
Morikawa, S.5
-
83
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
Sengupta, S.; Peterson, T.R.; Sabatini, D.M. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol. Cell 2010, 40, 310-322.
-
(2010)
Mol. Cell
, vol.40
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
84
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki, K.; Li, Y.; Zhu, T.; Wu, J.; Guan, K.L. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 2002, 4, 648-657.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
85
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma, X.M.; Blenis, J. Molecular mechanisms of mTOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 2009, 10, 307-318.
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
86
-
-
0034973856
-
Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signaling
-
Johnson, R.A.; Wang, X.; Ma, X.L.; Huong, S.M.; Huang, E.S. Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signaling. J. Virol. 2001, 75, 6022-6032.
-
(2001)
J. Virol
, vol.75
, pp. 6022-6032
-
-
Johnson, R.A.1
Wang, X.2
Ma, X.L.3
Huong, S.M.4
Huang, E.S.5
-
87
-
-
4644252994
-
Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase
-
Kudchodkar, S.B.; Yu, Y.; Maguire, T.G.; Alwine, J.C. Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase. J. Virol. 2004, 78, 11030-11039.
-
(2004)
J. Virol
, vol.78
, pp. 11030-11039
-
-
Kudchodkar, S.B.1
Yu, Y.2
Maguire, T.G.3
Alwine, J.C.4
-
88
-
-
20744448501
-
Regulation of the translation initiation factor eIF4F by multiple mechanisms in human cytomegalovirus-infected cells
-
Walsh, D.; Perez, C.; Notary, J.; Mohr, I. Regulation of the translation initiation factor eIF4F by multiple mechanisms in human cytomegalovirus-infected cells. J. Virol. 2005, 79, 8057-8064.
-
(2005)
J. Virol
, vol.79
, pp. 8057-8064
-
-
Walsh, D.1
Perez, C.2
Notary, J.3
Mohr, I.4
-
89
-
-
33749040235
-
Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes
-
Kudchodkar, S.B.; Yu, Y.; Maguire, T.G.; Alwine, J.C. Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes. Proc. Natl. Acad. Sci. USA 2006, 103, 14182-14187.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14182-14187
-
-
Kudchodkar, S.B.1
Yu, Y.2
Maguire, T.G.3
Alwine, J.C.4
-
90
-
-
17444368316
-
Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A
-
Moody, C.A.; Scott, R.S.; Amirghahari, N.; Nathan, C.O.; Young, L.S.; Dawson, C.W.; Sixbey, J.W. Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A. J. Virol. 2005, 79, 5499-5506.
-
(2005)
J. Virol
, vol.79
, pp. 5499-5506
-
-
Moody, C.A.1
Scott, R.S.2
Amirghahari, N.3
Nathan, C.O.4
Young, L.S.5
Dawson, C.W.6
Sixbey, J.W.7
-
91
-
-
64049114343
-
PI3K signaling regulates rapamycin-insensitive translation initiation complex formation in vaccinia virus-infected cells
-
Zaborowska, I.; Walsh, D. PI3K signaling regulates rapamycin-insensitive translation initiation complex formation in vaccinia virus-infected cells. J. Virol. 2009, 83, 3988-3992.
-
(2009)
J. Virol
, vol.83
, pp. 3988-3992
-
-
Zaborowska, I.1
Walsh, D.2
-
92
-
-
28344447599
-
Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A
-
Pim, D.; Massimi, P.; Dilworth, S.M.; Banks, L. Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A. Oncogene 2005, 24, 7830-7838.
-
(2005)
Oncogene
, vol.24
, pp. 7830-7838
-
-
Pim, D.1
Massimi, P.2
Dilworth, S.M.3
Banks, L.4
-
93
-
-
77956024826
-
The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis
-
Spangle, J.M.; Munger, K. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. J. Virol. 2010, 84, 9398-9407.
-
(2010)
J. Virol
, vol.84
, pp. 9398-9407
-
-
Spangle, J.M.1
Munger, K.2
-
94
-
-
84874716169
-
Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy
-
Surviladze, Z.; Sterk, R.T.; DeHaro, S.A.; Ozbun, M.A. Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy. J. Virol. 2013, 87, 2508-2517.
-
(2013)
J. Virol
, vol.87
, pp. 2508-2517
-
-
Surviladze, Z.1
Sterk, R.T.2
Deharo, S.A.3
Ozbun, M.A.4
-
95
-
-
17144403770
-
Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication
-
O'Shea, C.; Klupsch, K.; Choi, S.; Bagus, B.; Soria, C.; Shen, J.; McCornmick, F.; Stokoe, D. Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication. EMBO J. 2005, 24, 1211-1221.
-
(2005)
EMBO J
, vol.24
, pp. 1211-1221
-
-
O'Shea, C.1
Klupsch, K.2
Choi, S.3
Bagus, B.4
Soria, C.5
Shen, J.6
McCornmick, F.7
Stokoe, D.8
-
96
-
-
84865836687
-
The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia
-
Zuurbier, L.; Petricoin, E.F., 3rd; Vuerhard, M.J.; Calvert, V.; Kooi, C.; Buijs-Gladdines, J.G.; Smits, W.K.; Sonneveld, E.; Veerman, A.J.; Kamps, W.A., et al. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia. Haematologica 2012, 97, 1405-1413.
-
(2012)
Haematologica
, vol.97
, pp. 1405-1413
-
-
Zuurbier, L.1
Petricoin III, E.F.2
Vuerhard, M.J.3
Calvert, V.4
Kooi, C.5
Buijs-Gladdines, J.G.6
Smits, W.K.7
Sonneveld, E.8
Veerman, A.J.9
Kamps, W.A.10
-
97
-
-
41749121487
-
Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro
-
Calzavara, E.; Chiaramonte, R.; Cesana, D.; Basile, A.; Sherbet, G.V.; Comi, P. Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro. J. Cell. Biochem. 2008, 103, 1405-1412.
-
(2008)
J. Cell. Biochem
, vol.103
, pp. 1405-1412
-
-
Calzavara, E.1
Chiaramonte, R.2
Cesana, D.3
Basile, A.4
Sherbet, G.V.5
Comi, P.6
|