메뉴 건너뛰기




Volumn 80, Issue 7, 2006, Pages 3341-3348

Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of ΔUS3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENYLATE CYCLASE ACTIVATOR; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; EPIDERMAL GROWTH FACTOR; FORSKOLIN; LACTACYSTIN; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEASOME INHIBITOR; PROTEIN KINASE B;

EID: 33645240426     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.7.3341-3348.2006     Document Type: Article
Times cited : (61)

References (48)
  • 1
    • 0021228172 scopus 로고
    • Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies
    • Ackermann, M., D. K. Braun, L. Pereira, and B. Roizman. 1984. Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies. J. Virol. 52:108-118.
    • (1984) J. Virol. , vol.52 , pp. 108-118
    • Ackermann, M.1    Braun, D.K.2    Pereira, L.3    Roizman, B.4
  • 4
    • 3042636651 scopus 로고    scopus 로고
    • S3 activates and functionally overlaps protein kinase a to block apoptosis
    • S3 activates and functionally overlaps protein kinase A to block apoptosis. Proc. Natl. Acad. Sci. USA 101:9411-9416.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9411-9416
    • Benetti, L.1    Roizman, B.2
  • 5
    • 0038702481 scopus 로고    scopus 로고
    • S3 protein kinase blocks caspase dependent double cleavage and activation of the proapoptotic protein BAD
    • S3 protein kinase blocks caspase dependent double cleavage and activation of the proapoptotic protein BAD. J. Virol. 77:6567-6573.
    • (2003) J. Virol. , vol.77 , pp. 6567-6573
    • Benetti, L.1    Munger, J.2    Roizman, B.3
  • 6
    • 20444480256 scopus 로고    scopus 로고
    • SV40-dependent AKT activity drives mesothelial cell transformation after asbestos exposure
    • Cacciotti, P., D. Barbone, C. Porta, D. A. Altomare, J. R. Testa, L. Mutti, and G. Gaudino. 2005. SV40-dependent AKT activity drives mesothelial cell transformation after asbestos exposure. Cancer Res. 15:5256-5262.
    • (2005) Cancer Res. , vol.15 , pp. 5256-5262
    • Cacciotti, P.1    Barbone, D.2    Porta, C.3    Altomare, D.A.4    Testa, J.R.5    Mutti, L.6    Gaudino, G.7
  • 8
    • 0242377107 scopus 로고    scopus 로고
    • The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B
    • Cartier, A., E. Broberg, T. Komai, M. Henriksson, and M. G. Masucci. 2003. The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B. Cell Death Differ. 10:1320-1328.
    • (2003) Cell Death Differ. , vol.10 , pp. 1320-1328
    • Cartier, A.1    Broberg, E.2    Komai, T.3    Henriksson, M.4    Masucci, M.G.5
  • 9
    • 0242302347 scopus 로고    scopus 로고
    • The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosphorylation of the Bcl-2 family member Bad
    • Cartier, A., T. Komai, and M. G. Masucci. 2003. The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosphorylation of the Bcl-2 family member Bad. Exp. Cell Res. 291:242-250.
    • (2003) Exp. Cell Res. , vol.291 , pp. 242-250
    • Cartier, A.1    Komai, T.2    Masucci, M.G.3
  • 10
    • 0026539149 scopus 로고
    • 134.5 gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programmed cell death in neuronal cells
    • 134.5 gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programmed cell death in neuronal cells. Proc. Natl. Acad. Sci. USA 89:3266-3270.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3266-3270
    • Chou, J.1    Roizman, B.2
  • 11
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta, S. R., A. Brunet, and M. E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13:2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 12
    • 0022358365 scopus 로고
    • Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4
    • DeLuca, N. A., M. McCarth, and P. A. Schaffer. 1985. Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56:558-570.
    • (1985) J. Virol. , vol.56 , pp. 558-570
    • Deluca, N.A.1    McCarth, M.2    Schaffer, P.A.3
  • 13
    • 0032584081 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner
    • Galvan, V., and B. Roizman. 1998. Herpes simplex virus type 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. Proc. Natl. Acad. Sci. USA 95:3931-3936.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3931-3936
    • Galvan, V.1    Roizman, B.2
  • 14
    • 0033050202 scopus 로고    scopus 로고
    • Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death
    • Galvan, V., R. Brandimarti, and B. Roizman. 1999. Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death. J. Virol. 73:3219-3226.
    • (1999) J. Virol. , vol.73 , pp. 3219-3226
    • Galvan, V.1    Brandimarti, R.2    Roizman, B.3
  • 15
    • 0032749021 scopus 로고    scopus 로고
    • Antiapoptotic activity of herpes simplex virus type 2: The role of US3 protein kinase gene
    • Hata, S., A. H. Koyama, H. Shiota, A. Adachi, F. Goshima, and Y. Nishiyama. 1999. Antiapoptotic activity of herpes simplex virus type 2: the role of US3 protein kinase gene. Microbes Infect. 1:601-607.
    • (1999) Microbes Infect. , vol.1 , pp. 601-607
    • Hata, S.1    Koyama, A.H.2    Shiota, H.3    Adachi, A.4    Goshima, F.5    Nishiyama, Y.6
  • 16
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signaling
    • Janssens, V., and J. Goris. 2001. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signaling. Biochem. J. 353:417-439.
    • (2001) Biochem. J. , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 17
    • 0032830315 scopus 로고    scopus 로고
    • Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3
    • Jerome, K. R., R. Fox, Z. Chen, A. E. Sears, and L. Corey. 1999. Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3. J. Virol. 73:8950-8957.
    • (1999) J. Virol. , vol.73 , pp. 8950-8957
    • Jerome, K.R.1    Fox, R.2    Chen, Z.3    Sears, A.E.4    Corey, L.5
  • 20
    • 0034973856 scopus 로고    scopus 로고
    • Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signaling
    • Johnson, R. A., X. Wang, X. L. Ma, S. M. Huong, and E. S. Huang. 2001. Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signaling. J. Virol. 75:6022-6032.
    • (2001) J. Virol. , vol.75 , pp. 6022-6032
    • Johnson, R.A.1    Wang, X.2    Ma, X.L.3    Huong, S.M.4    Huang, E.S.5
  • 22
    • 0031041895 scopus 로고    scopus 로고
    • Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells
    • Koyama, A. H., and Y. Miwa. 1997. Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells. J. Virol. 71:2567-2571.
    • (1997) J. Virol. , vol.71 , pp. 2567-2571
    • Koyama, A.H.1    Miwa, Y.2
  • 23
    • 20744441155 scopus 로고    scopus 로고
    • Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection
    • Lee, C. J., C. L. Liao, and Y. L. Lin. 2005. Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J. Virol. 79:8388-8399.
    • (2005) J. Virol. , vol.79 , pp. 8388-8399
    • Lee, C.J.1    Liao, C.L.2    Lin, Y.L.3
  • 24
    • 0029843942 scopus 로고    scopus 로고
    • The herpes simplex major regulatory protein ICP4 blocks apoptosis induced by the virus or hyperthermia
    • Leopardi, R., and B. Roizman. 1996. The herpes simplex major regulatory protein ICP4 blocks apoptosis induced by the virus or hyperthermia. Proc. Natl. Acad. Sci. USA 93:9583-9587.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9583-9587
    • Leopardi, R.1    Roizman, B.2
  • 25
    • 0030878879 scopus 로고    scopus 로고
    • The herpes simplex virus 1 protein kinase Us3 is required for protection from apoptosis induced by the virus
    • Leopardi, R., C. Van Sant, and B. Roizman. 1997. The herpes simplex virus 1 protein kinase Us3 is required for protection from apoptosis induced by the virus. Proc. Natl. Acad. Sci. USA 94:7891-7896.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7891-7896
    • Leopardi, R.1    Van Sant, C.2    Roizman, B.3
  • 26
    • 21644460984 scopus 로고    scopus 로고
    • Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: Control of cell survival and viral replication
    • Mannova, P., and L. Beretta. 2005. Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication. J. Virol. 79:8742-8749.
    • (2005) J. Virol. , vol.79 , pp. 8742-8749
    • Mannova, P.1    Beretta, L.2
  • 27
    • 20444507288 scopus 로고    scopus 로고
    • JNK and PI3K/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells
    • Mizutani, T., S. Fukushi, M. Saijo, I. Kurane, and S. Morikawa. 2005. JNK and PI3K/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells. Biochim. Biophys. Acta 1741:4-10.
    • (2005) Biochim. Biophys. Acta , vol.1741 , pp. 4-10
    • Mizutani, T.1    Fukushi, S.2    Saijo, M.3    Kurane, I.4    Morikawa, S.5
  • 29
    • 0035964094 scopus 로고    scopus 로고
    • S3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins
    • S3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proc. Natl. Acad. Sci. USA 98:10410-10415.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10410-10415
    • Munger, J.1    Roizman, B.2
  • 30
    • 0034997338 scopus 로고    scopus 로고
    • S3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage
    • S3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. J. Virol. 75:5491-5497.
    • (2001) J. Virol. , vol.75 , pp. 5491-5497
    • Munger, J.1    Chee, A.V.2    Roizman, B.3
  • 31
    • 0037225685 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKCζ-MEK-ERK signaling pathway in target cells early during infection: Implications for infectivity
    • Naranatt, P. P., S. M. Akula, C. A. Zien, H. H. Krishnan, and B. Chandran. 2003. Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKCζ-MEK-ERK signaling pathway in target cells early during infection: implications for infectivity. J. Virol. 77:1524-1539.
    • (2003) J. Virol. , vol.77 , pp. 1524-1539
    • Naranatt, P.P.1    Akula, S.M.2    Zien, C.A.3    Krishnan, H.H.4    Chandran, B.5
  • 32
    • 1342279571 scopus 로고    scopus 로고
    • S3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members
    • S3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members. Virology 319:212-224.
    • (2004) Virology , vol.319 , pp. 212-224
    • Ogg, P.D.1    McDonell, P.J.2    Ryckman, B.J.3    Knudson, C.M.4    Roller, R.J.5
  • 33
    • 0036145517 scopus 로고    scopus 로고
    • The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway
    • Perkins, D., E. F. R. Pereira, M. Gober, P. J. Yarowsky, and L. Aurelian. 2002. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. J. Virol. 76:1435-1449.
    • (2002) J. Virol. , vol.76 , pp. 1435-1449
    • Perkins, D.1    Pereira, E.F.R.2    Gober, M.3    Yarowsky, P.J.4    Aurelian, L.5
  • 34
    • 20744442545 scopus 로고    scopus 로고
    • S3 protein kinase that exhibits altered functions
    • S3 protein kinase that exhibits altered functions. J. Virol. 79:8470-8479.
    • (2005) J. Virol. , vol.79 , pp. 8470-8479
    • Poon, A.P.W.1    Roizman, B.2
  • 35
    • 0242661003 scopus 로고    scopus 로고
    • Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0
    • Poon, A. P. W., Y. Liang, and B. Roizman. 2003. Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0. J. Virol. 77:12671-12678.
    • (2003) J. Virol. , vol.77 , pp. 12671-12678
    • Poon, A.P.W.1    Liang, Y.2    Roizman, B.3
  • 36
    • 9644279753 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Rasa/PI3K/Akt pathway
    • Portis, T., and R. Longnecker. 2004. Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Rasa/PI3K/Akt pathway. Oncogene 23:8619-8628.
    • (2004) Oncogene , vol.23 , pp. 8619-8628
    • Portis, T.1    Longnecker, R.2
  • 38
    • 25144461602 scopus 로고    scopus 로고
    • Corneal cell survival in adenovirus type 19 infection requires phosphoinositide 3-kinase/Akt activation
    • Rajala, M. S., R. V. S. Rajala, R. A. Astley, A. L. Butt, and J. Chodosh. 2005. Corneal cell survival in adenovirus type 19 infection requires phosphoinositide 3-kinase/Akt activation. J. Virol. 79:12332-12341.
    • (2005) J. Virol. , vol.79 , pp. 12332-12341
    • Rajala, M.S.1    Rajala, R.V.S.2    Astley, R.A.3    Butt, A.L.4    Chodosh, J.5
  • 40
    • 0035413602 scopus 로고    scopus 로고
    • Physiological substrates of cAMP-dependent protein kinase
    • Shabb, J. B. 2001. Physiological substrates of cAMP-dependent protein kinase. Chem. Rev. 101:2381-2411.
    • (2001) Chem. Rev. , vol.101 , pp. 2381-2411
    • Shabb, J.B.1
  • 41
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • Song, G., G. Ouyang, and S. Bao. 2005. The activation of Akt/PKB signaling pathway and cell survival. J. Cell Mol. Med. 9:59-71.
    • (2005) J. Cell Mol. Med. , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 42
    • 16244364798 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription
    • Street, A., A. Macdonald, C. McCormick, and M. Harris. 2005. Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin- responsive transcription. J. Virol. 79:5006-5016.
    • (2005) J. Virol. , vol.79 , pp. 5006-5016
    • Street, A.1    Macdonald, A.2    McCormick, C.3    Harris, M.4
  • 43
    • 0035949699 scopus 로고    scopus 로고
    • AKT plays a central role in tumorigenesis
    • Testa, J. R., and A. Bellacosa. 2001. AKT plays a central role in tumorigenesis. Proc. Natl. Acad. Ssi. USA 98:10983-10985.
    • (2001) Proc. Natl. Acad. Ssi. USA , vol.98 , pp. 10983-10985
    • Testa, J.R.1    Bellacosa, A.2
  • 45
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholmyl)-8-phenyl-4H-1-benzopyran-4-one (LY 294002)
    • Vlahos, C. J., W. F. Matter, K. Y. Hui, and R. F. Brown. 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholmyl)-8-phenyl-4H-1- benzopyran-4-one (LY 294002). J. Biol. Chem. 269:5241-5248.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 46
    • 0028791442 scopus 로고
    • Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεRI-mediated signal transduction
    • Yano, H., T. Agatsuma, S. Nakanishi, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1995. Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεRI-mediated signal transduction. Biochem. J. 312:145-150.
    • (1995) Biochem. J. , vol.312 , pp. 145-150
    • Yano, H.1    Agatsuma, T.2    Nakanishi, S.3    Saitoh, Y.4    Fukui, Y.5    Nonomura, Y.6    Matsuda, Y.7
  • 47
    • 0036200413 scopus 로고    scopus 로고
    • Human cytomegalovirus major immediate early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3′-OH pathway and the cellular kinase Akt
    • Yu, Y., and J. C. Alwine. 2002. Human cytomegalovirus major immediate early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3′-OH pathway and the cellular kinase Akt. J. Virol. 76:3731-3738.
    • (2002) J. Virol. , vol.76 , pp. 3731-3738
    • Yu, Y.1    Alwine, J.C.2
  • 48
    • 0034468747 scopus 로고    scopus 로고
    • Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins
    • Zhou, G., V. Galvan, G. Campadelli-Fiume, and B. Roizman. 2000. Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. J. Virol. 74:11782-11791.
    • (2000) J. Virol. , vol.74 , pp. 11782-11791
    • Zhou, G.1    Galvan, V.2    Campadelli-Fiume, G.3    Roizman, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.