Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signaling

Journal of Virology

Volumn 75, Issue 13, 2001, Pages 6022-6032

  Johnson, R A ^a   Wang, X ^a   Ma, X L ^a   Huong, S M ^a   Huang, E S ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BISINDOLYLMALEIMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; RAPAMYCIN; VERAPAMIL; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOMEGALIC INCLUSION BODY DISEASE; DNA REPLICATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; ULTRAVIOLET IRRADIATION; VIRUS REPLICATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE; CHROMONES; CYTOMEGALOVIRUS; DNA REPLICATION; GENE EXPRESSION REGULATION, VIRAL; HUMANS; MORPHOLINES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; UP-REGULATION; VIRUS REPLICATION;

EID: 0034973856     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.13.6022-6032.2001     Document Type: Article

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