The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins

EMBO Journal

Volumn 20, Issue 4, 2001, Pages 864-871

  Nilsson, Camilla Estmer ^a   Petersen Mahrt, Svend ^a,b   Durot, Céline ^c   Shtrichman, Ronit ^d,e   Krainer, Adrian R ^f   Kleinberger, Tamar ^d   Akusjärvi, Göran ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MRC LMB   (United Kingdom)

^c UNIVERSITÉ DE LYON   (France)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

Adenovirus; E4 ORF protein; Protein phosphatase 2A; Splicing enhancer; SR proteins

Indexed keywords

ADENOVIRUS E4 ORF4 PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; DEPHOSPHORYLATION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA SPLICING;

ADENOVIRUS E4 PROTEINS; HELA CELLS; HUMANS; NEOPLASM PROTEINS; OPEN READING FRAMES; PHOSPHORYLATION; PROTEIN BINDING; RNA SPLICING;

ADENOVIRIDAE;

EID: 0035865268     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.4.864     Document Type: Article

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34. Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs
35. The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation
36. The protein kinase Clk/Sty directly modulates SR protein activity: Both hyper- and hypophosphorylation inhibit splicing
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38. A monoclonal antibody that recognizes a phosphorylated epitope stains lampbrush chromosome loops and small granules in the amphibian germinal vesicle
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